MrtfbGt(RRJ478)Byg
Gene trapped Allele Detail
|
Symbol: |
MrtfbGt(RRJ478)Byg |
Name: |
myocardin related transcription factor B; gene trap RRJ478, BayGenomics |
MGI ID: |
MGI:3587937 |
Synonyms: |
Mkl2Gt(pGT0Lxf)1Ucd, MRTF-Bdelta |
Gene: |
Mrtfb Location: Chr16:13074345-13235393 bp, + strand Genetic Position: Chr16, 9.24 cM
|
Alliance: |
MrtfbGt(RRJ478)Byg page
|
|
Mutant Cell Line: |
RRJ478 |
Germline Transmission: |
Earliest citation of germline transmission:
J:160964
|
Parent Cell Line: |
E14TG2a (ES Cell)
|
Strain of Origin: |
129P2/OlaHsd
|
|
Allele Type: |
|
Gene trapped (Null/knockout, Reporter) |
Mutation: |
|
Insertion of gene trap vector
Vector: pGT0Lxf
|
|
|
Mutation details: A gene trap vector was inserted into intron 10, resulting in the production of a fusion protein encoded by the first 10 exons of MKL/myocardin-like 2 fused in-frame to a beta-galactosidase-neomycin phosphotransferase II reporter gene. Northern blot failed to detect transcript in mutants.
(J:117226, J:160964)
|
Sequence Tags: |
|
Sequence tag details (1 tag)
Tag ID |
GenBank ID |
Method |
Tag Location (trapped strand)* |
Select |
|
Genome Context: |
|
Genome Browser view of this mutation
23 gene trap insertions have trapped this gene
View all gene trap sequence tags in this region
|
|
|
|
View phenotypes and curated references for all genotypes (concatenated display).
|
|
|
Original: |
J:160964 Li J, et al., Myocardin-related transcription factor B is required in cardiac neural crest for smooth muscle differentiation and cardiovascular development. Proc Natl Acad Sci U S A. 2005 Jun 21;102(25):8916-21 |
All: |
3 reference(s) |
|