Gt(ROSA)26Sor^tm2(DTA)Riet
Targeted Allele Detail

Summary

• Symbol: Gt(ROSA)26Sor^tm2(DTA)Riet
• Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 2, Dieter Riethmacher
• MGI ID: MGI:3653504
• Synonyms: R26:lacZbpA^floxDTA
• Gene: Gt(ROSA)26Sor Location: Chr6:113044389-113054205 bp, - strand Genetic Position: Chr6, 52.73 cM
• Alliance: Gt(ROSA)26Sor^tm2(DTA)Riet page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:110983
• Parent Cell Line: E14.1 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Conditional ready, Inserted expressed sequence, No functional change, Reporter)
• Mutation: Insertion
• Mutation details: A targeting vector was designed to insert a splice acceptor sequence, a floxed lacZ-bpA, a DT-A cassette and a PGK-neo into intron 1. (J:110983)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gt(ROSA)26Sor Mutation: 942 strains or lines available

References

• Original: J:110983 Brockschnieder D, et al., An improved mouse line for Cre-induced cell ablation due to diphtheria toxin A, expressed from the Rosa26 locus. Genesis. 2006 Jul;44(7):322-7
• All: 17 reference(s)