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Disease Ontology Browser
Alzheimer's disease (DOID:10652)
Alliance: disease page
Synonyms: Alzheimer disease; Alzheimers dementia
Alt IDs: EFO:0000249, ICD10CM:G30, ICD9CM:331.0, KEGG:05010, MESH:D000544, NCI:C2866, UMLS_CUI:C0002395
Definition: A tauopathy that is characterized by memory lapses, confusion, emotional instability and progressive loss of mental ability and results in progressive memory loss, impaired thinking, disorientation, and changes in personality and mood starting and leads in advanced cases to a profound decline in cognitive and physical functioning and is marked histologically by the degeneration of brain neurons especially in the cerebral cortex and by the presence of neurofibrillary tangles and plaques containing beta-amyloid.

Disease References using Mouse Models (601)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
10/20/2020
MGI 6.16 		The Jackson Laboratory