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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Col1a1
collagen, type I, alpha 1
MGI:88467
321 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
ApcMin/Apc+
Col1a1tm1(CAG-Sirt1)Dsin/Col1a1+
involves: 129S4/SvJae * C57BL/6 * C57BL/6J 		anemia J:134301
cachexia J:134301
increased gastrointestinal tumor incidence J:134301
ApcMin/Apc+
Col1a1tm1(CAG-Sirt1)Dsin/Col1a1+
Tg(Vil1-cre)997Gum/0
involves: 129S4/SvJae * C57BL/6 * C57BL/6J * SJL 		decreased tumor incidence J:134301
ApcMin/Apc+
Col1a1tm9(tetO-Dnmt3b_i1)Jae/Col1a1+
Gt(ROSA)26Sortm1(rtTA*M2)Jae/Gt(ROSA)26Sor+
involves: 129S4/SvJae * C57BL/6 * C57BL/6J 		abnormal DNA methylation J:127808
increased intestinal adenoma incidence J:127808
increased tumor growth/size J:127808
ApcMin/Apc+
Col1a1tm10(tetO-Dnmt3b_i3)Jae/Col1a1+
Gt(ROSA)26Sortm1(rtTA*M2)Jae/Gt(ROSA)26Sor+
involves: 129S4/SvJae * C57BL/6 * C57BL/6J 		normal neoplasm J:127808
ApcMin/Apc+
Col1a1tm11(tetO-Dnmt3b_i6)Jae/Col1a1+
Gt(ROSA)26Sortm1(rtTA*M2)Jae/Gt(ROSA)26Sor+
involves: 129S4/SvJae * C57BL/6 * C57BL/6J 		normal neoplasm J:127808
ApcMin/Apc+
Col1a1tm12(tetO-Dnmt3a_i1)Jae/Col1a1+
Gt(ROSA)26Sortm1(rtTA*M2)Jae/Gt(ROSA)26Sor+
involves: 129S4/SvJae * C57BL/6 * C57BL/6J 		normal neoplasm J:127808
ApcMin/Apc+
Col1a1tm11(tetO-Nup88)Jvd/Col1a1+
involves: 129S4/SvJae * C57BL/6 * C57BL/6J 		increased colon tumor incidence J:231166
Atg5tm1.1Myok/Atg5tm1.1Myok
Col1a1tm3(tetO-Pou5f1,-Sox2,-Klf4,-Myc)Jae/Col1a1+
involves: 129S/SvEv * 129S4/SvJae * C57BL/6 * FVB/N 		abnormal cell physiology J:205532
Cdkn2atm1Rdp/Cdkn2atm1Rdp
Col1a1tm1(CAG-EGFR)Char/Col1a1tm1(CAG-EGFR)Char
Ptentm1Hwu/Ptentm1Hwu
involves: 129/Sv * 129S4/SvJae * C57BL/6 * SJL 		decreased tumor-free survival time J:146494
increased glioblastoma incidence J:146494
Cdkn2atm1Rdp/Cdkn2atm1Rdp
Col1a1tm1(CAG-EGFR)Char/Col1a1tm2(CAG-EGFR*)Char
Ptentm1Hwu/Ptentm1Hwu
involves: 129/Sv * 129S4/SvJae * C57BL/6 * SJL 		decreased tumor-free survival time J:146494
increased glioblastoma incidence J:146494
Cdkn2atm1Rdp/Cdkn2atm1Rdp
Col1a1tm2(CAG-EGFR*)Char/Col1a1tm2(CAG-EGFR*)Char
Ptentm1Hwu/Ptentm1Hwu
involves: 129/Sv * 129S4/SvJae * C57BL/6 * SJL 		decreased tumor-free survival time J:146494
increased glioblastoma incidence J:146494
Col1a1tm1(CAG-EGFR*T790M*C797S*L858R)Mje/Col1a1+
involves: 129S4/SvJae * BALB/c * C57BL/6 		increased lung adenocarcinoma incidence J:235747
Col1a1tm1(CAG-Ezh2*)Meln/Col1a1+
Ighg1tm1(cre)Cgn/Ighg1+
involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6 		normal immune system phenotype J:199122
increased germinal center B cell number J:199122
increased spleen germinal center number J:199122
increased spleen germinal center size J:199122
normal neoplasm J:199122
Col1a1tm1(CAG-Mir22)Ppp/Col1a1tm1(CAG-Mir22)Ppp
Tg(Mx1-cre)1Cgn/0
Not Specified 		abnormal erythropoiesis J:199366
abnormal hematopoietic system morphology/development J:199366
anemia J:199366
decreased leukocyte cell number J:199366
enlarged spleen J:199366
increased hematopoietic stem cell number J:199366
increased leukemia incidence J:199366
increased myeloid dendritic cell number J:199366
increased T cell derived lymphoma incidence J:199366
Col1a1tm1(CAG-Sirt2)Jmi/Col1a1+
Tg(Mpz-cre)26Mes/0
involves: 129S4/SvJae * C57BL/6 * FVB/N 		abnormal myelination J:177468
abnormal response to nerve crush injury J:177468
Col1a1tm1(hs1473-PITX1)Smun/Col1a1+
involves: 129S4/SvJae * C57BL/6 		abnormal digit morphology J:203670
abnormal forelimb morphology J:203670
abnormal forelimb zeugopod morphology J:203670
abnormal humerus morphology J:203670
fused carpal bones J:203670
oligodactyly J:203670
syndactyly J:203670
Col1a1tm1(tetO-CDKN2A)Ibp/Col1a1+
Tg(KRT5-rtTA)#Glk/0
involves: 129S4/SvJae * C57BL/6 * FVB 		abnormal hair cycle J:196969
abnormal hair follicle development J:196969
abnormal skin physiology J:196969
alopecia J:196969
decreased hair follicle number J:196969
early cellular replicative senescence J:196969
thick epidermis J:196969
Col1a1tm1(tetO-CDKN2A)Ibp/Col1a1tm2(tetO-GFP/RNAi:Trp53)Slowe
Tg(KRT5-rtTA)#Glk/0
involves: 129S4/SvJae * C57BL/6 * FVB 		normal cellular phenotype J:196969
normal integument phenotype J:196969
Col1a1tm1(tetO-cre)Haho/?
Gfi1btm1.1Haho/Gfi1btm1.1Haho
involves: 129S4/SvJaeSor * C57BL/6 		abnormal megakaryocyte differentiation J:207446
abnormal megakaryocyte progenitor cell morphology J:207446
absent erythroid progenitor cell J:207446
absent platelets J:207446
anemia J:207446
decreased hemoglobin content J:207446
postnatal lethality, complete penetrance J:207446
thrombocytopenia J:207446
Col1a1tm1(tetO-CTNNB1)Tcd/Col1a1+
Gt(ROSA)26Sortm1(rtTA*M2)Jae/Gt(ROSA)26Sor+
involves: 129S4/SvJae * C57BL/6 * C57BL/6J 		abnormal crypts of Lieberkuhn morphology J:193365
abnormal enterocyte apoptosis J:193365
abnormal enterocyte proliferation J:193365
abnormal intestine development J:193365
decreased body weight J:193365
normal digestive/alimentary phenotype J:193365
increased enterocyte apoptosis J:193365
Col1a1tm1(tetO-Cyp26b1)Mfra/Col1a1+
Gt(ROSA)26Sortm1(rtTA*M2)Jae/Gt(ROSA)26Sor+
involves: 129S4/SvJae * C57BL/6 		abnormal lymphatic vessel morphology J:206581
Col1a1tm1(tetO-Deptor)Dmsa/Col1a1+
Gt(ROSA)26Sortm1(rtTA*M2)Jae/?
involves: 129S4/SvJae * C57BL/6 * C57BL/6J 		hepatic steatosis J:187378
increased circulating leptin level J:187378
increased liver weight J:187378
increased susceptibility to diet-induced obesity J:187378
increased triglyceride level J:187378
increased white adipose tissue amount J:187378
Col1a1tm1(tetO-EML4/ALK)Kkw/Col1a1+
Tg(Scgb1a1-rtTA)1Jaw/0
involves: 129 * C57BL/6 		abnormal tumor pathology J:166724
increased lung carcinoma incidence J:166724
increased lung tumor incidence J:166724
premature death J:166724
normal respiratory system phenotype J:166724
weight loss J:166724
Col1a1tm1(tetO-EWSR1/ATF1)Yasu/Col1a1+
Gt(ROSA)26Sortm1(rtTA*M2)Jae/Gt(ROSA)26Sor+
involves: 129S4/SvJae * C57BL/6 		decreased fibroblast proliferation J:194505
increased sarcoma incidence J:194505
premature death J:194505
tumor regression J:194505
Col1a1tm1(tetO-EWSR1/ATF1)Yasu/Col1a1+
Gt(ROSA)26Sortm1(rtTA*M2)Jae/Gt(ROSA)26Sor+
H2az2Tg(Wnt1-cre)11Rth/H2az2+
Tg(CAG-cat,-lacZ)11Miya/0
involves: 129S4/SvJae * C57BL/6 * CBA/J * DBA/2 		increased sarcoma incidence J:194505
Col1a1tm1(tetO-EWSR1/ATF1)Yasu/Col1a1+
Gt(ROSA)26Sortm1(rtTA*M2)Jae/Gt(ROSA)26Sortm1(EYFP)Cos
Tg(Mpz-cre)94Imeg/0
involves: 129S4/SvJae * 129X1/SvJ * C57BL/6 		increased sarcoma incidence J:194505
Col1a1tm1(tetO-Fos)Wag/Col1a1+
Rag1tm1Mom/Rag1tm1Mom
Tg(KRT5-rtTA)T2D6Sgkd/0
involves: 129S4/SvJae * 129S7/SvEvBrd * C57BL/6 * FVB/N 		normal integument phenotype J:201145
skin hyperplasia J:201145
skin lesions J:201145
Col1a1tm1(tetO-Fos)Wag/Col1a1+
Gt(ROSA)26Sortm1(rtTA,EGFP)Nagy/Gt(ROSA)26Sor+
Tg(Alb1-cre)7Gsc/0
involves: 129 * C57BL/6 * FVB/N 		abnormal liver morphology J:210545
premature death J:210545
Col1a1tm1(tetO-Fos)Wag/Col1a1+
Tg(KRT5-rtTA)T2D6Sgkd/0
involves: 129S4/SvJae * C57BL/6 * FVB/N 		abnormal forestomach morphology J:201145
absent hair follicles J:201145
alopecia J:201145
decreased body size J:201145
epidermal hyperplasia J:201145
hyperkeratosis J:201145
normal immune system phenotype J:201145
increased CD4-positive, alpha-beta T cell number J:201145
increased granulocyte number J:201145
increased incidence of tumors by chemical induction J:201145
increased keratinocyte proliferation J:201145
increased papilloma incidence J:201145
parakeratosis J:201145
premature death J:201145
skin hyperplasia J:201145
skin inflammation J:201145
skin lesions J:201145
thick skin J:201145
Col1a1tm1(tetO-GFP,-RNAi:Eef1a1)Mcg/Col1a1+
Tg(Prkcd-glc-1/CFP,-cre)EH124Gsat/0
involves: C57BL/6J * FVB/NTac 		abnormal cued conditioning behavior J:297390
decreased anxiety-related response J:297390
Col1a1tm1(tetO-GFP,-RNAi:Eef1a1)Mcg/Col1a1+
Ssttm2.1(cre)Zjh/Sst+
involves: 129S4/SvJae * C57BL/6J 		normal behavior/neurological phenotype J:297390
impaired cued conditioning behavior J:297390
Col1a1tm1(tetO-GFP/RNAi:luc)Slowe/Col1a1+
Gt(ROSA)26Sortm1(rtTA*M2)Jae/Gt(ROSA)26Sor+
involves: 129S4/SvJae * C57BL/6 		no abnormal phenotype detected J:171191
Col1a1tm1(tetO-GFP/RNAi:Rad21)Iaai/Col1a1+
Gt(ROSA)26Sortm1(rtTA*M2)Jae/Gt(ROSA)26Sor+
involves: 129S4/SvJae * C57BL/6 		abnormal bone marrow cell number J:229031
abnormal definitive hematopoiesis J:229031
abnormal hematopoietic stem cell morphology J:229031
decreased B cell number J:229031
extramedullary hematopoiesis J:229031
increased hematopoietic stem cell number J:229031
increased myeloid cell number J:229031
Col1a1tm1(tetO-Irf4)Sing/Col1a1tm1(tetO-Irf4)Sing
Gt(ROSA)26Sortm1(rtTA*M2)Jae/Gt(ROSA)26Sor+
Irf4tm1Mak/Irf4+
involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6 		abnormal class switch recombination J:203903
abnormal plasma cell differentiation J:203903
Col1a1tm1(tetO-Irf4)Sing/Col1a1tm1(tetO-Irf4)Sing
Gt(ROSA)26Sortm1(rtTA*M2)Jae/Gt(ROSA)26Sor+
Irf4tm1Mak/Irf4tm1Mak
involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6 		abnormal class switch recombination J:203903
abnormal plasma cell differentiation J:203903
Col1a1tm1(tetO-Lin28a)Gqda/Col1a1+
involves: 129S4/SvJae * C57BL/6 * CD-1 		abnormal digestive system morphology J:166568
abnormal skeleton morphology J:166568
big ears J:166568
broad face J:166568
coarse hair J:166568
decreased circulating glucose level J:166568
decreased circulating insulin level J:166568
decreased susceptibility to age related obesity J:177113
decreased susceptibility to diet-induced hepatic steatosis J:177113
decreased susceptibility to diet-induced obesity J:177113
decreased total body fat amount J:177113
delayed female fertility J:166568
delayed sexual maturation J:166568
delayed vaginal opening J:166568
improved glucose tolerance J:166568, J:177113
increased body length J:166568
increased body size J:166568
increased body weight J:166568
increased bone mineral content J:166568
increased bone mineral density J:166568
increased cell proliferation J:166568
increased growth rate J:166568
increased hepatocyte proliferation J:166568
increased insulin sensitivity J:166568, J:177113
increased lean body mass J:177113
increased litter size J:166568
liver hyperplasia J:166568
premature death J:166568
normal reproductive system phenotype J:166568
skin hyperplasia J:166568
small pancreatic islets J:166568
thick skin J:166568
Col1a1tm1(tetO-RNAi:Rps19)Karl/Col1a1+
Gt(ROSA)26Sortm1(rtTA*M2)Jae/Gt(ROSA)26Sortm1(rtTA*M2)Jae
involves: 129S4/SvJae * C57BL/6 		abnormal bone marrow cell morphology/development J:179085
abnormal bone marrow cell physiology J:179085
abnormal proerythroblast morphology J:179085
decreased bone marrow cell number J:179085
decreased erythrocyte cell number J:179085
decreased hematopoietic cell number J:179085
decreased lymphocyte cell number J:179085
decreased megakaryocyte cell number J:179085
macrocytosis J:179085
normal mortality/aging J:179085
postnatal growth retardation J:179085
reticulocytopenia J:179085
thrombocytosis J:179085
Col1a1tm1(tetO-RNAi:Rps19)Karl/Col1a1tm1(tetO-RNAi:Rps19)Karl
Gt(ROSA)26Sortm1(rtTA*M2)Jae/Gt(ROSA)26Sortm1(rtTA*M2)Jae
involves: 129S4/SvJae * C57BL/6 		abnormal bone marrow cell morphology/development J:179085
abnormal bone marrow cell physiology J:179085
abnormal large intestine morphology J:179085
abnormal proerythroblast morphology J:179085
decreased bone marrow cell number J:179085
decreased erythrocyte cell number J:179085
decreased hematopoietic cell number J:179085
decreased lymphocyte cell number J:179085
decreased megakaryocyte cell number J:179085
decreased neutrophil cell number J:179085
macrocytosis J:179085
postnatal growth retardation J:179085
premature death J:179085
reticulocytopenia J:179085
thrombocytopenia J:179085
thrombocytosis J:179085
Col1a1tm1(tetO-SOX2)Mjm/Col1a1+
Gt(ROSA)26Sortm1(tTA)Roos/Gt(ROSA)26Sor+
Lgr5tm1(cre/ERT2)Cle/Lgr5+
involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6 * DBA/2J 		abnormal ileum crypts of Lieberkuhn morphology J:199754
abnormal intestine physiology J:199754
ectopic Paneth cells J:199754
increased cell proliferation J:199754
Col1a1tm1(tetO-Stat1)Biat/Col1a1tm1(tetO-Stat1)Biat
Gt(ROSA)26Sortm1(rtTA*M2)Jae/Gt(ROSA)26Sortm1(rtTA*M2)Jae
Stat1tm1Dlv/Stat1tm1Dlv
involves: 129S/SvEv * 129S4/SvJae * C57BL/6 		abnormal susceptibility to infection induced morbidity/mortality J:212694
Col1a1tm1(tetO-Tcfap2c)Hsc/Col1a1+
Gt(ROSA)26Sortm1(rtTA*M2)Jae/Gt(ROSA)26Sor+
involves: 129S4/SvJae * C57BL/6 		abnormal circulating enzyme level J:174049
abnormal enterocyte proliferation J:174049
abnormal hepatocyte mitochondrial morphology J:174049
abnormal hepatocyte morphology J:174049
abnormal intestinal mucosa morphology J:174049
abnormal intestine development J:174049
abnormal pancreas physiology J:174049
abnormal small intestine morphology J:174049
decreased liver glycogen level J:174049
dehydration J:174049
normal immune system phenotype J:174049
increased circulating alanine transaminase level J:174049
increased circulating alkaline phosphatase level J:174049
increased circulating amylase level J:174049
increased circulating aspartate transaminase level J:174049
increased circulating lactate dehydrogenase level J:174049
increased hepatocyte apoptosis J:174049
increased hepatocyte proliferation J:174049
lethargy J:174049
liver failure J:174049
microvesicular hepatic steatosis J:174049
premature death J:174049
weight loss J:174049
Col1a1tm1(tetO-U2AF1*S34F)Mjwa/Col1a1+
Gt(ROSA)26Sortm1(rtTA*M2)Jae/?
involves: 129S4/SvJae * C57BL/6 		abnormal definitive hematopoiesis J:221403
Col1a1tm1(tetO-URI1)Ndj/Col1a1+
Tg(Cebpb-tTA)#Bjd/0
B6.Cg-Col1a1tm1(tetO-URI1)Ndj Tg(Cebpb-tTA)#Bjd 		abnormal enzyme/coenzyme level J:217463
abnormal liver morphology J:217463
decreased circulating glucose level J:217463
increased bile salt level J:217463
increased circulating alanine transaminase level J:217463
increased circulating serum albumin level J:217463
increased hepatocellular carcinoma incidence J:217463
increased incidence of tumors by chemical induction J:217463
increased liver adenoma incidence J:217463
increased metastatic potential J:217463
liver failure J:217463
liver fibrosis J:217463
premature death J:217463
Col1a1tm1(tetO-URI1)Ndj/Col1a1+
Tg(Cebpb-tTA)#Bjd/0
Trp53tm1Gev/Trp53+
B6.Cg-Trp53tm1Gev Col1a1tm1(tetO-URI1)Ndj Tg(Cebpb-tTA)#Bjd 		decreased hepatocyte apoptosis J:217463
increased hepatocellular carcinoma incidence J:217463
premature death J:217463
Col1a1tm1(tetO-URI1)Ndj/Col1a1tm1(tetO-URI1)Ndj
Tg(Cebpb-tTA)#Bjd/0
B6.Cg-Col1a1tm1(tetO-URI1)Ndj Tg(Cebpb-tTA)#Bjd 		increased hepatocellular carcinoma incidence J:217463
Col1a1tm1(tetO-Vegfc)Mmul/Col1a1+
involves: 129S4/SvJae * C57BL/6 		no abnormal phenotype detected J:82809
Col1a1tm1(tetO-YAP1*)Fcam/Col1a1+
Gt(ROSA)26Sortm1(rtTA,EGFP)Nagy/Gt(ROSA)26Sor+
Tg(Pbsn-cre)4Prb/0
involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * C57BL/6 * DBA/2 		increased prostate gland adenocarcinoma incidence J:222916
increased prostate gland tumor incidence J:222916
Col1a1tm1(tetO-YAP1*)Fcam/Col1a1+
Gt(ROSA)26Sortm1(rtTA,EGFP)Nagy/Gt(ROSA)26Sor+
Tg(KRT14-cre)1Amc/0
involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * C57BL/6 * CBA 		abnormal epidermal layer morphology J:171057
abnormal epidermal stem cell morphology J:171057
abnormal hair growth J:171057
abnormal tongue epithelium morphology J:171057
hyperkeratosis J:171057
increased cell proliferation J:171057
increased skin squamous cell carcinoma incidence J:171057
thick epidermis J:171057
thick skin J:171057
wrinkled skin J:171057
Col1a1tm1(tetO-YAP1*)Fcam/Col1a1+
Gt(ROSA)26Sortm1(rtTA*M2)Jae/Gt(ROSA)26Sor+
involves: 129S4/SvJae * C57BL/6 		abnormal enterocyte proliferation J:141457
abnormal intestinal epithelium morphology J:141457
abnormal intestinal goblet cell morphology J:141457
absent Paneth cells J:141457
decreased alkaline phosphatase activity J:141457
enlarged pancreas J:141457
increased cell proliferation J:141457
increased pancreatic acinar cell number J:141457
pancreatic acinar-to-ductal metaplasia J:141457
premature death J:141457
thick skin J:141457
Col1a1tm1(tetO-YAP1*)Fcam/Col1a1+
Tg(Cebpb-tTA)#Bjd/0
involves: 129S4/SvJae * C57BL/6 		abnormal hepatocyte morphology J:141457
decreased hepatocyte apoptosis J:141457
enlarged liver J:141457
increased hepatocyte proliferation J:141457
increased liver weight J:141457
liver hyperplasia J:141457
Col1a1tm1(tetO-Yap1*)Lrsn/Col1a1+
Gt(ROSA)26Sortm1(rtTA*M2)Jae/Gt(ROSA)26Sor+
involves: 129S4/SvJae * C57BL/6 		premature death J:185310
Col1a1tm1(tetO-Yod1*)Hpl/Col1a1tm1(tetO-Yod1*)Hpl
Gt(ROSA)26Sortm1(rtTA*M2)Jae/Gt(ROSA)26Sortm1(rtTA*M2)Jae
involves: 129S4/SvJae * C57BL/6 		abnormal CD8-positive, alpha-beta T cell physiology J:194608
abnormal professional antigen presenting cell physiology J:194608
normal immune system phenotype J:194608
Col1a1tm1(tetO-Yod1*)Hpl/Col1a1tm1(tetO-Yod1*)Hpl
Gt(ROSA)26Sortm1(rtTA*M2)Jae/Gt(ROSA)26Sortm1(rtTA*M2)Jae
Tap1tm1Arp/Tap1tm1Arp
involves: 129S2/SvPas * 129S4/SvJae * C57BL/6 		abnormal professional antigen presenting cell physiology J:194608
Col1a1tm2(CAG-IDH2*R172K)Kkw/Col1a1+
Ndor1Tg(UBC-cre/ERT2)1Ejb/0
involves: 129S/SvEv * 129S4/SvJae * BALB/c * C57BL/6 		abnormal mitochondrial crista morphology J:209629
abnormal mitochondrial morphology J:209629
abnormal mitochondrial physiology J:209629
abnormal myocardial fiber mitochondrial morphology J:209629
abnormal myocardial fiber morphology J:209629
abnormal sarcomere morphology J:209629
abnormal skeletal muscle fiber mitochondrial morphology J:209629
abnormal skeletal muscle morphology J:209629
abnormal Z line morphology J:209629
blood vessel congestion J:209629
brain vacuoles J:209629
cardiac fibrosis J:209629
decreased cardiac muscle contractility J:209629
decreased mitochondrial number J:209629
dilated cardiomyopathy J:209629
enlarged heart J:209629
increased cardiac muscle glycogen level J:209629
increased cardiomyocyte apoptosis J:209629
increased skeletal muscle glycogen level J:209629
lethargy J:209629
neurodegeneration J:209629
premature death J:209629
respiratory distress J:209629
skeletal muscle endomysial fibrosis J:209629
skeletal muscle fiber degeneration J:209629
skeletal muscle fiber necrosis J:209629
Col1a1tm2(tetO-CTNNB1*)Hoch/Col1a1tm2(tetO-CTNNB1*)Hoch
Gt(ROSA)26Sortm1(rtTA*M2)Jae/?
involves: 129S4/SvJae * C57BL/6 		abnormal crypts of Lieberkuhn morphology J:191050
abnormal intestinal epithelium morphology J:191050
abnormal intestinal goblet cell morphology J:191050
abnormal large intestine crypts of Lieberkuhn morphology J:191050
abnormal small intestine crypts of Lieberkuhn morphology J:191050
Col1a1tm2(tetO-Fosl2,-DsRed)Wag/Col1a1+
Tg(Cebpb-tTA)5Bjd/0
involves: 129S4/SvJae * C57BL/6 * NMRI 		decreased liver triglyceride level J:210545
decreased susceptibility to diet-induced hepatic steatosis J:210545
normal homeostasis/metabolism phenotype J:213764
Col1a1tm2(tetO-Fosl2,-DsRed)Wag/Col1a1+
Tg(Sp7-tTA,tetO-EGFP/cre)1Amc/0
involves: 129S4/SvJae * C57BL/6 * CD-1 		abnormal osteoblast morphology J:211215
abnormal osteoblast physiology J:211215
abnormal osteoclast morphology J:211215
normal adipose tissue phenotype J:211215
decreased body weight J:211215
decreased circulating adiponectin level J:211215
decreased circulating glucose level J:211215
decreased circulating insulin level J:211215
decreased gonadal fat pad weight J:211215
decreased insulin secretion J:211215
improved glucose tolerance J:211215
increased bone ossification J:211215
increased bone trabecula number J:211215
increased bone volume J:211215
increased circulating osteocalcin level J:211215
increased insulin sensitivity J:211215
increased trabecular bone thickness J:211215
Col1a1tm2(tetO-GFP/RNAi:Smc1a)Iaai/Col1a1+
Gt(ROSA)26Sortm1(rtTA*M2)Jae/Gt(ROSA)26Sor+
involves: 129S4/SvJae * C57BL/6 		abnormal bone marrow cell number J:229031
abnormal definitive hematopoiesis J:229031
abnormal hematopoietic stem cell morphology J:229031
decreased B cell number J:229031
decreased hematopoietic stem cell number J:229031
enlarged spleen J:229031
extramedullary hematopoiesis J:229031
increased bone marrow cell number J:229031
increased granulocyte monocyte progenitor cell number J:229031
increased hematopoietic stem cell number J:229031
increased myeloid cell number J:229031
increased neutrophil cell number J:229031
increased spleen red pulp amount J:229031
myeloid hyperplasia J:229031
myeloid metaplasia J:229031
Col1a1tm2(tetO-GFP/RNAi:Smc1a)Iaai/Col1a1tm3(tetO-GFP/RNAi:Stag2)Iaai
Gt(ROSA)26Sortm1(rtTA*M2)Jae/Gt(ROSA)26Sor+
involves: 129S4/SvJae * C57BL/6 		abnormal definitive hematopoiesis J:229031
abnormal spleen morphology J:229031
anemia J:229031
decreased B cell number J:229031
enlarged spleen J:229031
myeloid hyperplasia J:229031
Col1a1tm2(tetO-IDH2*R140Q)Ppp/Col1a1tm2(tetO-IDH2*R140Q)Ppp
Flt3tm1.1Dosm/Flt3tm1.1Dosm
Gt(ROSA)26Sortm1(rtTA*M2)Jae/?
involves: 129 * C57BL/6 		increased leukemia incidence J:210097
premature death J:210097
Col1a1tm2(tetO-IDH2*R140Q)Ppp/Col1a1tm2(tetO-IDH2*R140Q)Ppp
Gt(ROSA)26Sortm1(rtTA*M2)Jae/?
involves: 129S4/SvJae * C57BL/6 		abnormal hematopoietic stem cell proliferation J:210097
enlarged spleen J:210097
extramedullary hematopoiesis J:210097
normal hematopoietic system phenotype J:210097
increased hematopoietic stem cell proliferation J:210097
increased leukemia incidence J:210097
normal neoplasm J:210097
Col1a1tm2(tetO-LIN28B)Gqda/Col1a1+
Gt(ROSA)26Sortm1(rtTA,EGFP)Nagy/Gt(ROSA)26Sor+
Tg(Cdh16-cre)91Igr/0
involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * C57BL/6 * ICR 		normal renal/urinary system phenotype J:211179
Col1a1tm2(tetO-LIN28B)Gqda/Col1a1+
Gt(ROSA)26Sortm1(rtTA,EGFP)Nagy/Gt(ROSA)26Sor+
Wt1tm2(cre/ERT2)Wtp/Wt1+
involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * C57BL/6 		abnormal kidney mesenchyme morphology J:211179
delayed kidney development J:211179
increased kidney tumor incidence J:211179
kidney cyst J:211179
Col1a1tm2(tetO-LIN28B)Gqda/Col1a1+
Gt(ROSA)26Sortm1(rtTA,EGFP)Nagy/Gt(ROSA)26Sor+
Tg(Six2-EGFP/cre)1Amc/0
involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * C57BL/6 * CD-1 		kidney cyst J:211179
normal neoplasm J:211179
Col1a1tm2(tetO-LIN28B)Gqda/Col1a1+
Gt(ROSA)26Sortm1(rtTA*M2)Jae/Gt(ROSA)26Sor+
involves: 129S4/SvJae * C57BL/6 * CD-1 		decreased susceptibility to diet-induced obesity J:177113
hypoglycemia J:177113
improved glucose tolerance J:177113
increased insulin sensitivity J:177113
Col1a1tm2(tetO-LIN28B)Gqda/Col1a1+
Foxd1tm1(GFP/cre)Amc/Foxd1+
Gt(ROSA)26Sortm1(rtTA,EGFP)Nagy/Gt(ROSA)26Sor+
involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * C57BL/6 		hydronephrosis J:211179
normal neoplasm J:211179
Col1a1tm2(tetO-LIN28B)Gqda/Col1a1tm3(tetO-Mirlet7g/Mir21)Gqda
Gt(ROSA)26Sortm1(rtTA*M2)Jae/Gt(ROSA)26Sor+
involves: 129S4/SvJae * C57BL/6 * CD-1 		normal homeostasis/metabolism phenotype J:177113
Col1a1tm2(tetO-LIN28B)Gqda/Col1a1tm3(tetO-Mirlet7g/Mir21)Gqda
Gt(ROSA)26Sortm1(rtTA,EGFP)Nagy/Gt(ROSA)26Sor+
Wt1tm2(cre/ERT2)Wtp/Wt1+
involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * C57BL/6 		small kidney J:211179
Col1a1tm2(tetO-Pou5f1)Jae/Col1a1+
Gt(ROSA)26Sortm1(rtTA*M2)Jae/Gt(ROSA)26Sor+
involves: 129S4/SvJae * C57BL/6 		abnormal cell proliferation J:98920
abnormal epidermal layer morphology J:98920
abnormal forestomach morphology J:98920
abnormal hair follicle morphology J:98920
abnormal intermediate gastric gland morphology J:98920
abnormal intestinal epithelium morphology J:98920
abnormal small intestine morphology J:98920
abnormal stomach epithelium morphology J:98920
abnormal stomach glandular epithelium morphology J:98920
abnormal stomach mucosa morphology J:98920
dehydration J:98920
increased skin tumor incidence J:98920
lethargy J:98920
premature death J:98920
spleen atrophy J:98920
stomach epithelial hyperplasia J:98920
thymus atrophy J:98920
Col1a1tm2(tetO-Pou5f1)Jae/Col1a1+
Gt(ROSA)26Sortm1(tTA)Roos/Gt(ROSA)26Sor+
Lgr5tm1(cre/ERT2)Cle/Lgr5+
involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6 * DBA/2J 		abnormal intestine physiology J:199754
abnormal small intestine crypts of Lieberkuhn morphology J:199754
increased cell proliferation J:199754
Col1a1tm2(tetO-RNAi:Rps19)Karl/Col1a1+
Gt(ROSA)26Sortm1(rtTA*M2)Jae/Gt(ROSA)26Sortm1(rtTA*M2)Jae
involves: 129S4/SvJae * C57BL/6 		decreased erythrocyte cell number J:179085
decreased hematopoietic cell number J:179085
decreased lymphocyte cell number J:179085
macrocytosis J:179085
normal mortality/aging J:179085
postnatal growth retardation J:179085
reticulocytopenia J:179085
thrombocytopenia J:179085
thrombocytosis J:179085
Col1a1tm2(tetO-RNAi:Rps19)Karl/Col1a1tm2(tetO-RNAi:Rps19)Karl
Gt(ROSA)26Sortm1(rtTA*M2)Jae/Gt(ROSA)26Sortm1(rtTA*M2)Jae
involves: 129S4/SvJae * C57BL/6 		decreased erythrocyte cell number J:179085
decreased hematopoietic cell number J:179085
decreased lymphocyte cell number J:179085
decreased neutrophil cell number J:179085
macrocytosis J:179085
postnatal growth retardation J:179085
premature death J:179085
reticulocytopenia J:179085
thrombocytopenia J:179085
thrombocytosis J:179085
Col1a1tm2(tetO-U2AF1)Mjwa/Col1a1+
Gt(ROSA)26Sortm1(rtTA*M2)Jae/0
involves: 129S4/SvJae * C57BL/6 		normal hematopoietic system phenotype J:221403
Col1a1tm3(CAG-IDH2*R140Q)Kkw/Col1a1+
Tmem163Tg(ACTB-cre)2Mrt/0
involves: 129S4/SvJae * BALB/c * C57BL/6 * FVB/N 		cardiac hypertrophy J:209629
decreased body size J:209629
embryonic lethality, incomplete penetrance J:209629
hydrocephaly J:209629
premature death J:209629
seizures J:209629
tremors J:209629
Col1a1tm3(CAG-IDH2*R140Q)Kkw/Col1a1+
Ndor1Tg(UBC-cre/ERT2)1Ejb/0
involves: 129S/SvEv * 129S4/SvJae * BALB/c * C57BL/6 		abnormal mitochondrial crista morphology J:209629
abnormal mitochondrial morphology J:209629
abnormal mitochondrial physiology J:209629
abnormal myocardial fiber mitochondrial morphology J:209629
abnormal myocardial fiber morphology J:209629
abnormal sarcomere morphology J:209629
abnormal skeletal muscle fiber mitochondrial morphology J:209629
abnormal skeletal muscle morphology J:209629
abnormal Z line morphology J:209629
blood vessel congestion J:209629
brain vacuoles J:209629
cardiac fibrosis J:209629
decreased cardiac muscle contractility J:209629
decreased mitochondrial number J:209629
dilated cardiomyopathy J:209629
enlarged heart J:209629
increased cardiomyocyte apoptosis J:209629
increased skeletal muscle glycogen level J:209629
lethargy J:209629
neurodegeneration J:209629
premature death J:209629
respiratory distress J:209629
Col1a1tm3(tetO-Fosl1,-DsRed)Wag/Col1a1+
Tg(Cebpb-tTA)5Bjd/0
involves: 129S4/SvJae * C57BL/6 * NMRI 		abnormal liver morphology J:210545
decreased circulating alanine transaminase level J:210545, J:213764
decreased circulating cholesterol level J:213764
decreased circulating interleukin-6 level J:210545
decreased liver triglyceride level J:210545
decreased liver weight J:210545
decreased susceptibility to diet-induced hepatic steatosis J:210545
decreased susceptibility to injury J:213764
impaired glucose tolerance J:210545
increased bile salt level J:213764
increased circulating cholesterol level J:210545
increased circulating triglyceride level J:210545
increased liver weight J:213764
insulin resistance J:210545
liver inflammation J:210545
normal liver/biliary system phenotype J:213764
normal mortality/aging J:213764
Col1a1tm3(tetO-Fosl1,-DsRed)Wag/Col1a1+
Gt(ROSA)26Sortm1(rtTA*M2)Jae/Gt(ROSA)26Sor+
involves: 129S4/SvJae * C57BL/6 		abnormal skeleton morphology J:213764
ascites J:213764
enlarged spleen J:213764
lethargy J:213764
liver fibrosis J:213764
weight loss J:213764
Col1a1tm3(tetO-GFP/RNAi:Apc)Slowe/Col1a1+
Gt(ROSA)26Sortm1(rtTA*M2)Jae/Gt(ROSA)26Sor+
involves: 129S4/SvJae * C57BL/6 		abnormal forelimb morphology J:171191
abnormal hair follicle morphology J:171191
abnormal hindlimb morphology J:171191
decreased body size J:171191
delayed endochondral bone ossification J:171191
excessive hair J:171191
failure of endochondral bone ossification J:171191
fetal growth retardation J:171191
hydrops fetalis J:171191
increased leukemia incidence J:171191
increased lymphoma incidence J:171191
increased T cell derived lymphoma incidence J:171191
polydactyly J:171191
postnatal growth retardation J:171191
premature death J:171191
progressive hair loss J:171191
short snout J:171191
Col1a1tm3(tetO-GFP/RNAi:Stag2)Iaai/Col1a1+
Gt(ROSA)26Sortm1(rtTA*M2)Jae/Gt(ROSA)26Sor+
involves: 129S4/SvJae * C57BL/6 		abnormal definitive hematopoiesis J:229031
abnormal hematopoietic stem cell morphology J:229031
decreased B cell number J:229031
decreased hematopoietic stem cell number J:229031
increased myeloid cell number J:229031
Col1a1tm3(tetO-Mirlet7g/Mir21)Gqda/Col1a1+
involves: 129S4/SvJae * C57BL/6 		decreased neuronal stem cell self-renewal J:207231
Col1a1tm3(tetO-Mirlet7g/Mir21)Gqda/Col1a1+
Gt(ROSA)26Sortm1(rtTA*M2)Jae/Gt(ROSA)26Sor+
involves: 129S4/SvJae * C57BL/6 * CD-1 		decreased body size J:177113
impaired glucose tolerance J:177113
increased circulating glucose level J:177113
increased circulating insulin level J:177113
postnatal growth retardation J:177113
Col1a1tm3(tetO-Mirlet7g/Mir21)Gqda/Col1a1+
Myf5tm1(cre)Mrc/Myf5+
involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * C57BL/6 		decreased body length J:199720
decreased body size J:199720
Col1a1tm3(tetO-Mirlet7g/Mir21)Gqda/?
Gt(ROSA)26Sortm1(rtTA*M2)Jae/Gt(ROSA)26Sor+
involves: 129S4/SvJae * C57BL/6 		decreased primordial germ cell number J:196313
Col1a1tm3(tetO-Pou5f1,-Sox2,-Klf4,-Myc)Jae/Col1a1tm3(tetO-Pou5f1,-Sox2,-Klf4,-Myc)Jae
Gt(ROSA)26Sortm1(rtTA*M2)Jae/Gt(ROSA)26Sortm1(rtTA*M2)Jae
involves: 129S4/SvJae * C57BL/6 		no abnormal phenotype detected J:157298
Col1a1tm4(CAG-FGFR2_iIIIb*K660N)Kkw/Col1a1+
involves: 129S4/SvJae * BALB/c * C57BL/6 		increased lung tumor incidence J:214230
Col1a1tm4(CAG-FGFR2_iIIIb*K660N)Kkw/Col1a1+
Trp53tm1Brn/Trp53tm1Brn
involves: 129P2/OlaHsd * 129S4/SvJae * BALB/c * C57BL/6 		increased lung adenocarcinoma incidence J:214230
increased lung tumor incidence J:214230
premature death J:214230
respiratory distress J:214230
weight loss J:214230
Col1a1tm4(tetO-GFP/RNAi:Apc)Slowe/Col1a1+
Gt(ROSA)26Sortm1(rtTA*M2)Jae/Gt(ROSA)26Sor+
involves: 129S4/SvJae * C57BL/6 		abnormal hair follicle morphology J:171191
decreased body size J:171191
excessive hair J:171191
increased leukemia incidence J:171191
increased lymphoma incidence J:171191
increased T cell derived lymphoma incidence J:171191
postnatal growth retardation J:171191
premature death J:171191
progressive hair loss J:171191
short snout J:171191
Col1a1tm4(tetO-Jun/Fosl2)Wag/Col1a1+
Tg(Cebpb-tTA)5Bjd/0
involves: 129S4/SvJae * C57BL/6 * NMRI 		decreased liver triglyceride level J:210545
decreased susceptibility to diet-induced hepatic steatosis J:210545
Col1a1tm5(CAG-FGFR2_iIIIb*W290C)Kkw/Col1a1+
Trp53tm1Brn/Trp53tm1Brn
involves: 129P2/OlaHsd * 129S4/SvJae * BALB/c * C57BL/6 		increased lung tumor incidence J:214230
Col1a1tm5(tetO-GFP/RNAi:Cdkn2a)Slowe/Col1a1+
Gt(ROSA)26Sortm1(Luc)Kael/Gt(ROSA)26Sortm1(rtTA*M2)Jae
Krastm4Tyj/Kras+
Tg(Scgb1a1-rtTA)1Jaw/0
involves: 129S4/SvJae * 129S6/SvEvTac * C57BL/6 		cachexia J:171191
increased lung adenoma incidence J:171191
increased tumor incidence J:171191
premature death J:171191
respiratory distress J:171191
Col1a1tm5(tetO-Jun/Fos)Wag/Col1a1+
Gt(ROSA)26Sortm1(rtTA,EGFP)Nagy/Gt(ROSA)26Sor+
Tg(Alb1-cre)7Gsc/0
involves: 129 * C57BL/6 * FVB/N 		abnormal liver morphology J:210545
premature death J:210545
Col1a1tm6(tetO-MSI2)Jae/Col1a1+
Gt(ROSA)26Sortm1(rtTA*M2)Jae/Gt(ROSA)26Sor+
involves: 129S4/SvJae * C57BL/6 		abnormal bone marrow cell morphology/development J:163322
abnormal erythrocyte morphology J:163322
abnormal leukocyte morphology J:163322
abnormal myelopoiesis J:163322
decreased common myeloid progenitor cell number J:163322
decreased lymphocyte cell number J:163322
decreased neutrophil cell number J:163322
enlarged spleen J:163322
increased bone marrow cell number J:163322
increased erythrocyte cell number J:163322
increased hematocrit J:163322
increased hematopoietic stem cell number J:163322
increased leukemia incidence J:163322
increased leukocyte cell number J:163322
increased liver weight J:163322
increased mean corpuscular volume J:163322
increased spleen weight J:163322
increased susceptibility to induced morbidity/mortality J:163322
spleen hyperplasia J:163322
thrombocytopenia J:163322
Col1a1tm8(CAG-BDNF)Jae/Col1a1+
Mecp2tm1.1Jae/Y
Tg(Camk2a-cre)93Kln/0
involves: 129S4/SvJae * C57BL/6 * CBA/J 		abnormal action potential J:106973
normal behavior/neurological phenotype J:106973
decreased brain weight J:106973
premature death J:106973
Col1a1tm8(CAG-BDNF)Jae/Col1a1tm8(CAG-BDNF)Jae
Tg(Sim1-cre)1Lowl/0
involves: 129S4/SvJae * C57BL/6 * FVB 		abnormal hypothalamus physiology J:179918
normal homeostasis/metabolism phenotype J:179918
Col1a1tm8(tetO-GFP/RNAi:Rpa3)Slowe/Col1a1+
Tg(CMV-rtTA)4Bjd/0
involves: 129S4/SvJae * C57BL/6 * NMRI 		abnormal cell cycle J:171348
premature death J:171348
weight loss J:171348
Col1a1tm8(tetO-GFP/RNAi:Rpa3)Slowe/Col1a1+
Gt(ROSA)26Sortm1(rtTA*M2)Jae/Gt(ROSA)26Sor+
Tg(CMV-rtTA)4Bjd/0
involves: 129S4/SvJae * C57BL/6 * NMRI 		abnormal cell cycle J:171348
premature death J:171348
weight loss J:171348
Col1a1tm8(tetO-GFP/RNAi:Rpa3)Slowe/Col1a1+
Gt(ROSA)26Sortm1(rtTA*M2)Jae/Gt(ROSA)26Sortm1(rtTA*M2)Jae
involves: 129S4/SvJae * C57BL/6 		abnormal cell cycle J:171348
premature death J:171348
weight loss J:171348
Col1a1tm9(tetO-GFP/RNAi:Rpa3)Slowe/Col1a1+
Gt(ROSA)26Sortm1(rtTA*M2)Jae/Gt(ROSA)26Sor+
chimera involves: 129S4/SvJae * C57BL/6 		infertility J:171348
Col1a1tm10(tetO*-RFP/RNAi:Rpa3)Slowe/Col1a1+
Gt(ROSA)26Sortm1(rtTA*M2)Jae/Gt(ROSA)26Sor+
involves: 129S4/SvJae * C57BL/6 		abnormal cell cycle J:171348
early cellular replicative senescence J:171348
neonatal lethality, complete penetrance J:171348
no abnormal phenotype detected J:171348
Col1a1tm10(tetO*-RFP/RNAi:Rpa3)Slowe/Col1a1+
Gt(ROSA)26Sortm1(rtTA*M2)Jae/Gt(ROSA)26Sor+
Tg(CMV-rtTA)4Bjd/0
involves: 129S4/SvJae * C57BL/6 * NMRI 		premature death J:171348
weight loss J:171348
Col1a1tm10(tetO*-RFP/RNAi:Rpa3)Slowe/Col1a1+
Gt(ROSA)26Sortm1(rtTA*M2)Jae/Gt(ROSA)26Sortm1(rtTA*M2)Jae
involves: 129S4/SvJae * C57BL/6 		abnormal small intestinal crypt cell physiology J:171348
abnormal small intestinal crypt cell proliferation J:171348
decreased erythroid progenitor cell number J:171348
premature death J:171348
weight loss J:171348
Col1a1tm11(tetO*-RFP/RNAi:Rpa3)Slowe/Col1a1+
Gt(ROSA)26Sortm1(rtTA*M2)Jae/Gt(ROSA)26Sor+
involves: 129S4/SvJae * C57BL/6 		abnormal cell cycle J:171348
early cellular replicative senescence J:171348
neonatal lethality, complete penetrance J:171348
no abnormal phenotype detected J:171348
Col1a1tm11(tetO*-RFP/RNAi:Rpa3)Slowe/Col1a1+
Gt(ROSA)26Sortm1(rtTA*M2)Jae/Gt(ROSA)26Sor+
Tg(CMV-rtTA)4Bjd/0
involves: 129S4/SvJae * C57BL/6 * NMRI 		premature death J:171348
weight loss J:171348
Col1a1tm11(tetO*-RFP/RNAi:Rpa3)Slowe/Col1a1+
Gt(ROSA)26Sortm1(rtTA*M2)Jae/Gt(ROSA)26Sortm1(rtTA*M2)Jae
involves: 129S4/SvJae * C57BL/6 		abnormal small intestinal crypt cell physiology J:171348
abnormal small intestinal crypt cell proliferation J:171348
decreased erythroid progenitor cell number J:171348
premature death J:171348
weight loss J:171348
Col1a1tm11(tetO-Nup88)Jvd/Col1a1+
involves: 129S4/SvJae * C57BL/6 		abnormal cell cycle checkpoint function J:231166
abnormal mitosis J:231166
abnormal mitotic spindle morphology J:231166
aneuploidy J:231166
chromosomal instability J:231166
increased lung tumor incidence J:231166
increased tumor incidence J:231166
Col1a1tm13(tetO-Nup88)Jvd/Col1a1+
involves: 129S4/SvJae * C57BL/6 		abnormal cell cycle checkpoint function J:231166
abnormal mitosis J:231166
abnormal mitotic spindle morphology J:231166
aneuploidy J:231166
chromosomal instability J:231166
increased lung tumor incidence J:231166
increased tumor incidence J:231166
Col1a1tm17(tetO-GFP,-cas9*)Slowe/Col1a1+
Gt(ROSA)26Sortm1(rtTA*M2)Jae/Gt(ROSA)26Sor+
involves: 129S4/SvJae * C57BL/6 		abnormal small intestinal crypt cell physiology J:222595
abnormal small intestinal crypt cell proliferation J:222595
ectopic Paneth cells J:222595
Col1a1tm18(tetO-GFP,-cas9*)Slowe/Col1a1+
Gt(ROSA)26Sortm1(rtTA*M2)Jae/Gt(ROSA)26Sor+
involves: 129S4/SvJae * C57BL/6 		normal digestive/alimentary phenotype J:222595
Col1a1tm19(tetO-GFP,-cas9*)Slowe/Col1a1+
Gt(ROSA)26Sortm1(rtTA*M2)Jae/Gt(ROSA)26Sor+
involves: 129S4/SvJae * C57BL/6 		abnormal small intestinal crypt cell physiology J:222595
abnormal small intestinal crypt cell proliferation J:222595
ectopic Paneth cells J:222595
Col1a1tm20(tetO-GFP,-cas9*D10A)Slowe/Col1a1+
Gt(ROSA)26Sortm1(rtTA*M2)Jae/Gt(ROSA)26Sor+
involves: 129S4/SvJae * C57BL/6 		abnormal small intestinal crypt cell physiology J:222595
abnormal small intestinal crypt cell proliferation J:222595
ectopic Paneth cells J:222595
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MGI 6.24 		The Jackson Laboratory