Foxd1^{tm1(GFP/cre)Amc}
Targeted Allele Detail

Summary

• Symbol: Foxd1^{tm1(GFP/cre)Amc}
• Name: forkhead box D1; targeted mutation 1, Andrew P McMahon
• MGI ID: MGI:4359653
• Synonyms: FoxD1-cre, Foxd1EGFPcre, Foxd1GC, Foxd1^GC, FoxD1-GC, Foxd1-GFP-Cre
• Gene: Foxd1 Location: Chr13:98490753-98493213 bp, + strand Genetic Position: Chr13, 51.96 cM
• Alliance: Foxd1^{tm1(GFP/cre)Amc} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:148456
• Parent Cell Line: v6.5 (ES Cell)
• Strain of Origin: (C57BL/6 x 129S4/SvJae)F1

Mutation description

• Allele Type: Targeted (Recombinase)
• Mutation: Insertion
• Foxd1^{tm1(GFP/cre)Amc} expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Foxd1 (MGI:1347463)

• Mutation details: A targeting vector was designed to insert an eGFP/cre (GC) fusion protein coding sequence and frt-flanked PGK-neob-pA selection cassette into the 5' untranslated region of the Forkhead box D1 (Foxd1) targeted gene. (J:158051)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Foxd1 (mouse) Summary of all recombinase alleles driven by Foxd1. Comparative matrix view of recombinase activities Alliance mouse Foxd1 gene page

Expression

In Mice Carrying this Mutation:

138 assay results 7 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Foxd1 Mutation: 11 strains or lines available

References

• Original: J:148456 Humphreys BD, et al., Intrinsic epithelial cells repair the kidney after injury. Cell Stem Cell. 2008 Mar 6;2(3):284-91
• All: 81 reference(s)