Col1a1^{tm1(tetO-GFP,-RNAi:Eef1a1)Mcg}
Targeted Allele Detail

Summary

• Symbol: Col1a1^{tm1(tetO-GFP,-RNAi:Eef1a1)Mcg}
• Name: collagen, type I, alpha 1; targeted mutation 1, McGill University
• MGI ID: MGI:6693286
• Synonyms: Col1a1^{TRE GFP.shmiR-4E.389}
• Gene: Col1a1 Location: Chr11:94827050-94843868 bp, + strand Genetic Position: Chr11, 59.01 cM, cytoband D
• Alliance: Col1a1^{tm1(tetO-GFP,-RNAi:Eef1a1)Mcg} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:297390
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Inducible, Knockdown, Reporter)
• Inducer: doxycycline/tetracycline
• Mutation: Insertion
• Col1a1^{tm1(tetO-GFP,-RNAi:Eef1a1)Mcg} involves 1 genes/genome features (Eef1a1) View all
• Mutation details: The allele contains a tetracycline response element driving expression of a GFP reporter gene and short hairpin RNA targeting Eef1a1. (J:297390)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Col1a1 Mutation: 160 strains or lines available

References

• Original: J:297390 Shrestha P, et al., Amygdala inhibitory neurons as loci for translation in emotional memories. Nature. 2020 Oct;586(7829):407-411
• All: 2 reference(s)