Phenotypes associated with this allele
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Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Col1a1tm1(tetO-GFP,-RNAi:Eef1a1)Mcg mutation
(0 available);
any
Col1a1 mutation
(161 available)
Ssttm2.1(cre)Zjh mutation
(4 available);
any
Sst mutation
(35 available)
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behavior/neurological
N |
• mice virally expressing a cre-dependent tet transactivator exhibit normal behavior in an open field and exploration of an elevated plus maze
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• mice virally expressing a cre-dependent tet transactivator exhibit reduced long term memory in a cued threat-conditioning paradigm compared with wild-type
• however, supplementation with doxycycline rescues phenotype
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|
Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Col1a1tm1(tetO-GFP,-RNAi:Eef1a1)Mcg mutation
(0 available);
any
Col1a1 mutation
(161 available)
Tg(Prkcd-glc-1/CFP,-cre)EH124Gsat mutation
(1 available)
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behavior/neurological
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• mice virally expressing a cre-dependent tet transactivator exhibit impaired conditioned safety response to withdrawal of cued stimuli compared with wild-type mice
• however, acquisition of differential threat associative memory is normal
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• increased exploration of an elevated plus maze in mice virally expressing a cre-dependent tet transactivator
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