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Gene Expression Data
Assay Details
Assay
Reference: J:386951 Guertin TM, et al., Onset of embryonic and placental defects coincide in 19 of 22 novel mid-gestation lethal murine knockout lines. Development. 2026 May 15;153(10):dev205276
Assay type: RNA in situ
MGI Accession ID: MGI:8350481
Gene symbol: Tpbpa
Gene name: trophoblast specific protein alpha
Probe: 4311 probe
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 2D: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: spongiotrophoblast Present 2D Expression is seen in the spongiotrophoblast layer (SpT) of the junctional zone (JZ).
Specimen E8.5 - 3B; Ext1A: embryonic day 8.5 (more )
Note: Littermate control.
Structure Level Pattern Image Note
TS13: spongiotrophoblast Present Extended Data 1A E8.5 , 3B E8.5 Expressing cells are seen in the core of the ectoplacental cone (EPC) overlying the chorion.
Specimen E8.75 - Ext1A: embryonic day 8.75 (more )
Note: Littermate control.
Structure Level Pattern Image Note
TS13: spongiotrophoblast Present Extended Data 1A E8.75 Expression demonstrates the developmental progression of the layer.
Specimen E9.0 - 3B; Ext1A: embryonic day 9.0 (more )
Note: Littermate control.
Structure Level Pattern Image Note
TS14: spongiotrophoblast Present 3B E9.0 , Extended Data 1A E9.0 Expression demonstrates the developmental progression of the layer.
Specimen E9.25 - Ext1A: embryonic day 9.25 (more )
Note: Littermate control.
Structure Level Pattern Image Note
TS14: spongiotrophoblast Present Extended Data 1A E9.25 Expression demonstrates the developmental progression of the layer.
Specimen E9.5 - 3B; Ext1A: embryonic day 9.5 (more )
Note: Littermate control.
Structure Level Pattern Image Note
TS15: spongiotrophoblast Present 3B E9.5 , Extended Data 1A E9.5 Expression demonstrates the developmental progression of the layer.
Specimen E9.75 - 3B; Ext1A: embryonic day 9.75 (more )
Note: Littermate control.
Structure Level Pattern Image Note
TS15: spongiotrophoblast Present 3B E9.75 , Extended Data 1A E9.75 Expression demonstrates the developmental progression of the layer.
Specimen E10.0 - Ext1A: embryonic day 10.0 (more )
Note: Littermate control.
Structure Level Pattern Image Note
TS16: spongiotrophoblast Present Extended Data 1A E10.0 Expression demonstrates the developmental progression of the layer.
Specimen E10.5 - 3B; Ext1A: embryonic day 10.5 (more )
Note: Littermate control.
Structure Level Pattern Image Note
TS17: spongiotrophoblast Present Extended Data 1A E10.5 , 3B E10.5 The spongiotrophoblast layer overlies the entire labyrinthine zone.
Specimen 5A - Chp1 +/- E9.5; Ext8F: embryonic day 9.5; Chp1em1(IMPC)Tcp/Chp1+ (more )
Structure Level Pattern Image Note
TS15: spongiotrophoblast Present 5A Chp1+/- E9.5 Tpbpa , Extended Data 8F +/- Tpbpa
Specimen 5A - Chp1 -/- E9.5; Ext8F: embryonic day 9.5; Chp1em1(IMPC)Tcp/Chp1em1(IMPC)Tcp (more )
Structure Level Pattern Image Note
TS15: spongiotrophoblast Present Extended Data 8F -/- Tpbpa , 5A Chp1-/- E9.5 Tpbpa In mutants this layer is reduced compared to controls.
Specimen 5B - Alg3 +/- E10.5; Ext16H: embryonic day 10.5; Alg3em1(IMPC)J/Alg3+ (more )
Structure Level Pattern Image Note
TS17: spongiotrophoblast Present Extended Data 16H +/- Tpbpa , 5B Alg3+/- E10.5 Tpbpa
Specimen 5B - Alg3 -/- E10.5; Ext16H: embryonic day 10.5; Alg3em1(IMPC)J/Alg3em1(IMPC)J (more )
Structure Level Pattern Image Note
TS17: spongiotrophoblast Present 5B Alg3-/- E10.5 Tpbpa , Extended Data 16H -/- Tpbpa In mutants an expanded SpT layer was observed in 2 placentas whereas a reduction is observed in the other.
Specimen Atp1b1 +/- E9.5: embryonic day 9.5; Atp1b1em1(IMPC)Mbp/Atp1b1+ (more )
Structure Level Pattern Image Note
TS15: spongiotrophoblast Present Extended Data 2B +/- Tpbpa
Specimen Atp1b1 -/- E9.5: embryonic day 9.5; Atp1b1em1(IMPC)Mbp/Atp1b1em1(IMPC)Mbp (more )
Structure Level Pattern Image Note
TS15: spongiotrophoblast Present Extended Data 2B -/- Tpbpa In mutants this layer is comparable to that seen in controls.
Specimen Ehbp1 +/- E9.5: embryonic day 9.5; Ehbp1em1(IMPC)J/Ehbp1+ (more )
Structure Level Pattern Image Note
TS15: spongiotrophoblast Present Extended Data 3B +/- Tpbpa
Specimen Ehbp1 -/- E9.5: embryonic day 9.5; Ehbp1em1(IMPC)J/Ehbp1em1(IMPC)J (more )
Structure Level Pattern Image Note
TS15: spongiotrophoblast Present Extended Data 3B -/- Tpbpa In mutants this layer is comparable to that seen in controls.
Specimen Tedc2 +/- E9.5: embryonic day 9.5; Tedc2em1(IMPC)J/Tedc2+ (more )
Structure Level Pattern Image Note
TS15: spongiotrophoblast Present Extended Data 4B +/- Tpbpa
Specimen Tedc2 -/- E9.5: embryonic day 9.5; Tedc2em1(IMPC)J/Tedc2em1(IMPC)J (more )
Structure Level Pattern Image Note
TS15: spongiotrophoblast Present Extended Data 4B -/- Tpbpa In mutants this layer is comparable to that seen in controls.
Specimen Zmym2 +/- E9.5 - B: embryonic day 9.5; Zmym2em1(IMPC)J/Zmym2+ (more )
Structure Level Pattern Image Note
TS15: spongiotrophoblast Present Extended Data 5B +/- Tpbpa
Specimen Zmym2 -/- E9.5 - B: embryonic day 9.5; Zmym2em1(IMPC)J/Zmym2em1(IMPC)J (more )
Structure Level Pattern Image Note
TS15: spongiotrophoblast Present Extended Data 5B -/- Tpbpa In mutants development of this layer is variable. In the first 4 placentas examined, the layer was expanded compared to controls. However, in subsequent analyses, development of the layer was normal in 3 instances and reduced in 1.
Specimen Zmym2 +/- E9.5 - E: embryonic day 9.5; Zmym2em1(IMPC)J/Zmym2+ (more )
Structure Level Pattern Image Note
TS15: spongiotrophoblast Present Extended Data 5E +/- Tpbpa
Specimen Zmym2 -/- E9.5 - E: embryonic day 9.5; Zmym2em1(IMPC)J/Zmym2em1(IMPC)J (more )
Structure Level Pattern Image Note
TS15: spongiotrophoblast Present Extended Data 5E -/- Tpbpa In mutants development of this layer is variable. In the first 4 placentas examined, the layer was expanded compared to controls. However, in subsequent analyses, development of the layer was normal in 3 instances and reduced in 1.
Specimen Gcn1 +/- E9.5: embryonic day 9.5; Gcn1em1(IMPC)J/Gcn1+ (more )
Structure Level Pattern Image Note
TS15: spongiotrophoblast Present Extended Data 6B +/- Tpbpa
Specimen Gcn1 -/- E9.5 - #1: embryonic day 9.5; Gcn1em1(IMPC)J/Gcn1em1(IMPC)J (more )
Structure Level Pattern Image Note
TS15: spongiotrophoblast Present Extended Data 6B -/- #1 Tpbpa In mutants this layer is comparable to that seen in controls.
Specimen Gcn1 -/- E9.5 - #2: embryonic day 9.5; Gcn1em1(IMPC)J/Gcn1em1(IMPC)J (more )
Structure Level Pattern Image Note
TS15: spongiotrophoblast Present Extended Data 6B -/- #2 Tpbpa In mutants this layer is comparable to that seen in controls.
Specimen Slc30a9 Control E9.5: embryonic day 9.5 (more )
Note: Littermate control.
Structure Level Pattern Image Note
TS15: spongiotrophoblast Present Extended Data 7B Control Tpbpa
Specimen Slc30a9 -/- E9.5: embryonic day 9.5; Slc30a9em1(IMPC)Bay/Slc30a9em1(IMPC)Bay (more )
Structure Level Pattern Image Note
TS15: spongiotrophoblast Present Extended Data 7B -/- Tpbpa In mutants this layer is comparable to that seen in controls.
Specimen Chp1 +/- E9.5: embryonic day 9.5; Chp1em1(IMPC)Tcp/Chp1+ (more )
Structure Level Pattern Image Note
TS15: spongiotrophoblast Present Extended Data 8B +/- Tpbpa
Specimen Chp1 -/- E9.5 - #1: embryonic day 9.5; Chp1em1(IMPC)Tcp/Chp1em1(IMPC)Tcp (more )
Structure Level Pattern Image Note
TS15: spongiotrophoblast Present Extended Data 8B -/- #1 Tpbpa In mutants this layer is reduced compared to controls.
Specimen Chp1 -/- E9.5 - #2: embryonic day 9.5; Chp1em1(IMPC)Tcp/Chp1em1(IMPC)Tcp (more )
Structure Level Pattern Image Note
TS15: spongiotrophoblast Present Extended Data 8B -/- #2 Tpbpa In mutants this layer is reduced compared to controls.
Specimen Ppox +/- E9.5 - B: embryonic day 9.5; Ppoxem1(IMPC)J/Ppox+ (more )
Structure Level Pattern Image Note
TS15: spongiotrophoblast Present Extended Data 9B +/- Tpbpa
Specimen Ppox -/- E9.5 - B: embryonic day 9.5; Ppoxem1(IMPC)J/Ppoxem1(IMPC)J (more )
Structure Level Pattern Image Note
TS15: spongiotrophoblast Present Extended Data 9B -/- Tpbpa In mutants this layer is reduced compared to controls.
Specimen Ppox +/- E9.5 - D: embryonic day 9.5; Ppoxem1(IMPC)J/Ppox+ (more )
Structure Level Pattern Image Note
TS15: spongiotrophoblast Present Extended Data 9D +/- Tpbpa
Specimen Ppox -/- E9.5 - D: embryonic day 9.5; Ppoxem1(IMPC)J/Ppoxem1(IMPC)J (more )
Structure Level Pattern Image Note
TS15: spongiotrophoblast Present Extended Data 9D -/- Tpbpa In mutants this layer is reduced compared to controls.
Specimen Urm1 +/- E9.5 - B: embryonic day 9.5; Urm1em1(IMPC)J/Urm1+ (more )
Structure Level Pattern Image Note
TS15: spongiotrophoblast Present Extended Data 10B +/- Tpbpa
Specimen Urm1 -/- E9.5 - B: embryonic day 9.5; Urm1em1(IMPC)J/Urm1em1(IMPC)J (more )
Structure Level Pattern Image Note
TS15: spongiotrophoblast Present Extended Data 10B -/- Tpbpa In mutants this layer is reduced compared to controls.
Specimen Urm1 +/- E9.5 - E: embryonic day 9.5; Urm1em1(IMPC)J/Urm1+ (more )
Structure Level Pattern Image Note
TS15: spongiotrophoblast Present Extended Data 10E +/- Tpbpa
Specimen Urm1 -/- E9.5 - E: embryonic day 9.5; Urm1em1(IMPC)J/Urm1em1(IMPC)J (more )
Structure Level Pattern Image Note
TS15: spongiotrophoblast Present Extended Data 10E -/- Tpbpa In mutants this layer is reduced compared to controls.
Specimen Gmeb2 +/- E9.5 - B: embryonic day 9.5; Gmeb2em1(IMPC)J/Gmeb2+ (more )
Structure Level Pattern Image Note
TS15: spongiotrophoblast Present Extended Data 11B +/- Tpbpa
Specimen Gmeb2 -/- E9.5 - B: embryonic day 9.5; Gmeb2em1(IMPC)J/Gmeb2em1(IMPC)J (more )
Structure Level Pattern Image Note
TS15: spongiotrophoblast Present Extended Data 11B -/- Tpbpa In mutants this layer is reduced compared to controls.
Specimen Gmeb2 +/- E9.5 - E: embryonic day 9.5; Gmeb2em1(IMPC)J/Gmeb2+ (more )
Structure Level Pattern Image Note
TS15: spongiotrophoblast Present Extended Data 11E +/- Tpbpa
Specimen Gmeb2 -/- E9.5 - E: embryonic day 9.5; Gmeb2em1(IMPC)J/Gmeb2em1(IMPC)J (more )
Structure Level Pattern Image Note
TS15: spongiotrophoblast Present Extended Data 11E -/- Tpbpa In mutants this layer is reduced compared to controls.
Specimen Kctd5 +/- E9.5 - B: embryonic day 9.5; Kctd5em1(IMPC)J/Kctd5+ (more )
Structure Level Pattern Image Note
TS15: spongiotrophoblast Present Extended Data 12B +/- Tpbpa
Specimen Kctd5 -/- E9.5 - B: embryonic day 9.5; Kctd5em1(IMPC)J/Kctd5em1(IMPC)J (more )
Structure Level Pattern Image Note
TS15: spongiotrophoblast Present Extended Data 12B -/- Tpbpa In mutants this layer is reduced compared to controls.
Specimen Kctd5 +/- E9.5 - E: embryonic day 9.5; Kctd5em1(IMPC)J/Kctd5+ (more )
Structure Level Pattern Image Note
TS15: spongiotrophoblast Present Extended Data 12E +/- Tpbpa
Specimen Kctd5 -/- E9.5 - E: embryonic day 9.5; Kctd5em1(IMPC)J/Kctd5em1(IMPC)J (more )
Structure Level Pattern Image Note
TS15: spongiotrophoblast Present Extended Data 12E -/- Tpbpa In mutants this layer is reduced compared to controls.
Specimen Rprd2 +/- E9.5 - B: embryonic day 9.5; Rprd2em1(IMPC)J/Rprd2+ (more )
Structure Level Pattern Image Note
TS15: spongiotrophoblast Present Extended Data 13B +/- Tpbpa
Specimen Rprd2 -/- E9.5 - B: embryonic day 9.5; Rprd2em1(IMPC)J/Rprd2em1(IMPC)J (more )
Structure Level Pattern Image Note
TS15: spongiotrophoblast Present Extended Data 13B -/- Tpbpa In mutants this layer is reduced compared to controls.
Specimen Rprd2 +/- E9.5 - E: embryonic day 9.5; Rprd2em1(IMPC)J/Rprd2+ (more )
Structure Level Pattern Image Note
TS15: spongiotrophoblast Present Extended Data 13E +/- Tpbpa
Specimen Rprd2 -/- E9.5 - E: embryonic day 9.5; Rprd2em1(IMPC)J/Rprd2em1(IMPC)J (more )
Structure Level Pattern Image Note
TS15: spongiotrophoblast Present Extended Data 13E -/- Tpbpa In mutants this layer is reduced compared to controls.
Specimen Got2 +/- E9.5 - B: embryonic day 9.5; Got2em1(IMPC)Mbp/Got2+ (more )
Structure Level Pattern Image Note
TS15: spongiotrophoblast Present Extended Data 14B +/- Tpbpa
Specimen Got2 -/- E9.5 - B: embryonic day 9.5; Got2em1(IMPC)Mbp/Got2em1(IMPC)Mbp (more )
Structure Level Pattern Image Note
TS15: spongiotrophoblast Present Extended Data 14B -/- Tpbpa In mutants this layer is reduced compared to controls.
Specimen Got2 +/- E9.5 - E: embryonic day 9.5; Got2em1(IMPC)Mbp/Got2+ (more )
Structure Level Pattern Image Note
TS15: spongiotrophoblast Present Extended Data 14E +/- Tpbpa
Specimen Got2 -/- E9.5 - E: embryonic day 9.5; Got2em1(IMPC)Mbp/Got2em1(IMPC)Mbp (more )
Structure Level Pattern Image Note
TS15: spongiotrophoblast Present Extended Data 14E -/- Tpbpa In mutants this layer is reduced compared to controls.
Specimen Arpc1a +/- E9.5: embryonic day 9.5; Arpc1aem1(IMPC)J/Arpc1a+ (more )
Structure Level Pattern Image Note
TS15: spongiotrophoblast Present Extended Data 15B +/- Tpbpa
Specimen Arpc1a -/- E9.5: embryonic day 9.5; Arpc1aem1(IMPC)J/Arpc1aem1(IMPC)J (more )
Structure Level Pattern Image Note
TS15: spongiotrophoblast Present Extended Data 15B -/- Tpbpa In mutants this layer is comparable to that seen in controls.
Specimen Arpc1a +/- E10.5 - E: embryonic day 10.5; Arpc1aem1(IMPC)J/Arpc1a+ (more )
Structure Level Pattern Image Note
TS17: spongiotrophoblast Present Extended Data 15E +/- Tpbpa
Specimen Arpc1a -/- E10.5 - E: embryonic day 10.5; Arpc1aem1(IMPC)J/Arpc1aem1(IMPC)J (more )
Structure Level Pattern Image Note
TS17: spongiotrophoblast Present Extended Data 15E -/- Tpbpa In mutants development of this layer is variable. In the first 3 placentas examined, the layer was expanded compared to controls. However, in subsequent analyses, development of the layer was normal in 3 instances.
Specimen Arpc1a +/- E10.5 - H: embryonic day 10.5; Arpc1aem1(IMPC)J/Arpc1a+ (more )
Structure Level Pattern Image Note
TS17: spongiotrophoblast Present Extended Data 15H +/- Tpbpa
Specimen Arpc1a -/- E10.5 - H: embryonic day 10.5; Arpc1aem1(IMPC)J/Arpc1aem1(IMPC)J (more )
Structure Level Pattern Image Note
TS17: spongiotrophoblast Present Extended Data 15H -/- Tpbpa In mutants development of this layer is variable. In the first 3 placentas examined, the layer was expanded compared to controls. However, in subsequent analyses, development of the layer was normal in 3 instances.
Specimen Alg3 +/- E9.5: embryonic day 9.5; Alg3em1(IMPC)J/Alg3+ (more )
Structure Level Pattern Image Note
TS15: spongiotrophoblast Present Extended Data 16B +/- Tpbpa
Specimen Alg3 -/- E9.5: embryonic day 9.5; Alg3em1(IMPC)J/Alg3em1(IMPC)J (more )
Structure Level Pattern Image Note
TS15: spongiotrophoblast Present Extended Data 16B -/- Tpbpa In mutants this layer is comparable to that seen in controls.
Specimen Alg3 +/- E10.5 - E: embryonic day 10.5; Alg3em1(IMPC)J/Alg3+ (more )
Structure Level Pattern Image Note
TS17: spongiotrophoblast Present Extended Data 16E +/- Tpbpa
Specimen Alg3 -/- E10.5 - E: embryonic day 10.5; Alg3em1(IMPC)J/Alg3em1(IMPC)J (more )
Structure Level Pattern Image Note
TS17: spongiotrophoblast Present Extended Data 16E -/- Tpbpa In mutants an expanded SpT layer was observed in 2 placentas whereas a reduction is observed in the other.
Specimen Bltp2 +/- E9.5: embryonic day 9.5; Bltp2em1(IMPC)J/Bltp2+ (more )
Structure Level Pattern Image Note
TS15: spongiotrophoblast Present Extended Data 17B +/- Tpbpa
Specimen Bltp2 -/- E9.5: embryonic day 9.5; Bltp2em1(IMPC)J/Bltp2em1(IMPC)J (more )
Structure Level Pattern Image Note
TS15: spongiotrophoblast Present Extended Data 17B -/- Tpbpa In mutants this layer is comparable to that seen in controls.
Specimen Bltp2 +/- E10.5 - E: embryonic day 10.5; Bltp2em1(IMPC)J/Bltp2+ (more )
Structure Level Pattern Image Note
TS17: spongiotrophoblast Present Extended Data 17E +/- Tpbpa
Specimen Bltp2 -/- E10.5 - E: embryonic day 10.5; Bltp2em1(IMPC)J/Bltp2em1(IMPC)J (more )
Structure Level Pattern Image Note
TS17: spongiotrophoblast Present Extended Data 17E -/- Tpbpa In mutants this layer is reduced compared to controls.
Specimen Bltp2 +/- E10.5 - H: embryonic day 10.5; Bltp2em1(IMPC)J/Bltp2+ (more )
Structure Level Pattern Image Note
TS17: spongiotrophoblast Present Extended Data 17H +/- Tpbpa
Specimen Bltp2 -/- E10.5 - H: embryonic day 10.5; Bltp2em1(IMPC)J/Bltp2em1(IMPC)J (more )
Structure Level Pattern Image Note
TS17: spongiotrophoblast Present Extended Data 17H -/- Tpbpa In mutants this layer is reduced compared to controls.
Specimen Stt3b +/- E9.5: embryonic day 9.5; Stt3bem1(IMPC)J/Stt3b+ (more )
Structure Level Pattern Image Note
TS15: spongiotrophoblast Present Extended Data 18B +/- Tpbpa
Specimen Stt3b -/- E9.5: embryonic day 9.5; Stt3bem1(IMPC)J/Stt3bem1(IMPC)J (more )
Structure Level Pattern Image Note
TS15: spongiotrophoblast Present Extended Data 18B -/- Tpbpa In mutants this layer is comparable to that seen in controls.
Specimen Stt3b +/- E10.5: embryonic day 10.5; Stt3bem1(IMPC)J/Stt3b+ (more )
Structure Level Pattern Image Note
TS17: spongiotrophoblast Present Extended Data 18E +/- Tpbpa
Specimen Stt3b -/- E10.5: embryonic day 10.5; Stt3bem1(IMPC)J/Stt3bem1(IMPC)J (more )
Structure Level Pattern Image Note
TS17: spongiotrophoblast Present Extended Data 18E -/- Tpbpa In mutants this layer is comparable to that seen in controls.
Specimen Traf7 +/- E9.5: embryonic day 9.5; Traf7em1(IMPC)Tcp/Traf7+ (more )
Structure Level Pattern Image Note
TS15: spongiotrophoblast Present Extended Data 19B +/- Tpbpa
Specimen Traf7 -/- E9.5: embryonic day 9.5; Traf7em1(IMPC)Tcp/Traf7em1(IMPC)Tcp (more )
Structure Level Pattern Image Note
TS15: spongiotrophoblast Present Extended Data 19B -/- Tpbpa In mutants this layer is comparable to that seen in controls.
Specimen Traf7 +/- E10.5: embryonic day 10.5; Traf7em1(IMPC)Tcp/Traf7+ (more )
Structure Level Pattern Image Note
TS17: spongiotrophoblast Present Extended Data 19E +/- Tpbpa
Specimen Traf7 -/- E10.5: embryonic day 10.5; Traf7em1(IMPC)Tcp/Traf7em1(IMPC)Tcp (more )
Structure Level Pattern Image Note
TS17: spongiotrophoblast Present Extended Data 19E -/- Tpbpa In mutants this layer is comparable to that seen in controls.
Specimen Exoc3l4 +/- E9.5: embryonic day 9.5; Exoc3l4em1(IMPC)J/Exoc3l4+ (more )
Structure Level Pattern Image Note
TS15: spongiotrophoblast Present Extended Data 20B +/- Tpbpa
Specimen Exoc3l4 -/- E9.5: embryonic day 9.5; Exoc3l4em1(IMPC)J/Exoc3l4em1(IMPC)J (more )
Structure Level Pattern Image Note
TS15: spongiotrophoblast Present Extended Data 20B -/- Tpbpa In mutants this layer is reduced compared to controls.
Specimen Exoc3l4 +/- E10.5: embryonic day 10.5; Exoc3l4em1(IMPC)J/Exoc3l4+ (more )
Structure Level Pattern Image Note
TS17: spongiotrophoblast Present Extended Data 20D +/- Tpbpa
Specimen Exoc3l4 -/- E10.5: embryonic day 10.5; Exoc3l4em1(IMPC)J/Exoc3l4em1(IMPC)J (more )
Structure Level Pattern Image Note
TS17: spongiotrophoblast Present Extended Data 20D -/- Tpbpa In mutants there may be a slight developmental delay, but this phenotype was not consistent among all mutants examined.
Specimen Pgm1 +/- E9.5: embryonic day 9.5; Pgm1em1(IMPC)J/Pgm1+ (more )
Structure Level Pattern Image Note
TS15: spongiotrophoblast Present Extended Data 21B +/- Tpbpa
Specimen Pgm1 -/- E9.5: embryonic day 9.5; Pgm1em1(IMPC)J/Pgm1em1(IMPC)J (more )
Structure Level Pattern Image Note
TS15: spongiotrophoblast Present Extended Data 21B -/- Tpbpa In mutants this layer is comparable to that seen in controls.
Specimen Pgm1 +/- E10.5: embryonic day 10.5; Pgm1em1(IMPC)J/Pgm1+ (more )
Structure Level Pattern Image Note
TS17: spongiotrophoblast Present Extended Data 21E +/- Tpbpa
Specimen Pgm1 -/- E10.5: embryonic day 10.5; Pgm1em1(IMPC)J/Pgm1em1(IMPC)J (more )
Structure Level Pattern Image Note
TS17: spongiotrophoblast Present Extended Data 21E -/- Tpbpa In mutants this layer is comparable to that seen in controls.
Specimen Usb1 +/- E9.5: embryonic day 9.5; Usb1em1(IMPC)Bay/Usb1+ (more )
Structure Level Pattern Image Note
TS15: spongiotrophoblast Present Extended Data 22B +/- Tpbpa
Specimen Usb1 -/- E9.5: embryonic day 9.5; Usb1em1(IMPC)Bay/Usb1em1(IMPC)Bay (more )
Structure Level Pattern Image Note
TS15: spongiotrophoblast Present Extended Data 22B -/- Tpbpa In mutants this layer is comparable to that seen in controls.
Specimen Usb1 +/- E10.5: embryonic day 10.5; Usb1em1(IMPC)Bay/Usb1+ (more )
Structure Level Pattern Image Note
TS17: spongiotrophoblast Present Extended Data 22E +/- Tpbpa
Specimen Usb1 -/- E10.5: embryonic day 10.5; Usb1em1(IMPC)Bay/Usb1em1(IMPC)Bay (more )
Structure Level Pattern Image Note
TS17: spongiotrophoblast Present Extended Data 22E -/- Tpbpa In mutants this layer is comparable to that seen in controls.
Specimen Tgds +/- E9.5: embryonic day 9.5; Tgdsem1(IMPC)Mbp/Tgds+ (more )
Structure Level Pattern Image Note
TS15: spongiotrophoblast Present Extended Data 23B +/- Tpbpa
Specimen Tgds -/- E9.5: embryonic day 9.5; Tgdsem1(IMPC)Mbp/Tgdsem1(IMPC)Mbp (more )
Structure Level Pattern Image Note
TS15: spongiotrophoblast Present Extended Data 23B -/- Tpbpa In mutants this layer is comparable to that seen in controls. (Staining in the displayed mutant appears more intense than in controls, but this was not consistent in all mutants examined.)
Specimen Tgds +/- E10.5: embryonic day 10.5; Tgdsem1(IMPC)Mbp/Tgds+ (more )
Structure Level Pattern Image Note
TS17: spongiotrophoblast Present Extended Data 23E +/- Tpbpa
Specimen Tgds -/- E10.5: embryonic day 10.5; Tgdsem1(IMPC)Mbp/Tgdsem1(IMPC)Mbp (more )
Structure Level Pattern Image Note
TS17: spongiotrophoblast Present Extended Data 23E -/- Tpbpa In mutants this layer is comparable to that seen in controls.
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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09/15/2026
MGI 6.29 		The Jackson Laboratory