Atp1b1^em1(IMPC)Mbp
Endonuclease-mediated Allele Detail

Summary

• Symbol: Atp1b1^em1(IMPC)Mbp
• Name: ATPase, Na+/K+ transporting, beta 1 polypeptide; endonuclease-mediated mutation 1, Mouse Biology Program, UC Davis
• MGI ID: MGI:7425530
• Synonyms: Atp1b1^-
• Gene: Atp1b1 Location: Chr1:164264678-164285924 bp, - strand Genetic Position: Chr1, 71.75 cM
• Alliance: Atp1b1^em1(IMPC)Mbp page
• IMPC: Atp1b1 gene page

Atp1b1^em1(IMPC)Mbp/Atp1b1^em1(IMPC)Mbp embryos show growth retardation, abnormal embryo turning at E9.5, abnormal head shape, a slight kink in their caudal neural tube and defect in cranial neural tube closure, abnormal heart, and half show branchial arch defects.

Show the 4 phenotype image(s) involving this allele.

Mutation origin

• Strain of Origin: C57BL/6NCrl
• Project Collection: IMPC

Mutation description

Allele Type: Endonuclease-mediated (Null/knockout) Mutation: Intragenic deletion Inheritance: Not Specified

Strategy for the generation of the Atp1b1^em1(IMPC)Mbp allele.

Expression

In Mice Carrying this Mutation:	30 assay results
In Structures Affected by this Mutation:	15 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Atp1b1 Mutation: 20 strains or lines available

References

• Original: J:265051 MGI and IMPC, MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC). Database Release. 2018-2023
• All: 4 reference(s)