Phenotype Images associated with this Allele - MGI

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Phenotype Images associated with this Allele

Nomenclature

Symbol:	Atp1b1^em1(IMPC)Mbp
Name:	ATPase, Na+/K+ transporting, beta 1 polypeptide; endonuclease-mediated mutation 1, Mouse Biology Program, UC Davis
MGI ID:	MGI:7425530
Synonyms:	Atp1b1^-

Images for
Allele

Click images for details

Image	Caption	Genotypes involving this allele
Image	Caption	Allelic Composition	Genetic Background
	Atp1b1^em1(IMPC)Mbp/Atp1b1^em1(IMPC)Mbp embryos show growth retardation, abnormal embryo turning at E9.5, abnormal head shape, a slight kink in their caudal neural tube and defect in cranial neural tube closure, abnormal heart, and half show branchial arch defects.	Atp1b1^em1(IMPC)Mbp/Atp1b1^em1(IMPC)Mbp	C57BL/6NCrl-Atp1b1^em1(IMPC)Mbp/Mmucd
	AlleleSymbol(MGI:7425530\|0)/Atp1b1^em1(IMPC)Mbp embryos exhibit normal placentas.	Atp1b1^em1(IMPC)Mbp/Atp1b1^em1(IMPC)Mbp	C57BL/6NCrl-Atp1b1^em1(IMPC)Mbp/Mmucd
	E8.5 Atp1b1^em1(IMPC)Mbp/Atp1b1^em1(IMPC)Mbp embryos that are smaller than litter mates (but not grossly abnormal which represent a minority) have normal germ layer patterning.	Atp1b1^em1(IMPC)Mbp/Atp1b1^em1(IMPC)Mbp	C57BL/6NCrl-Atp1b1^em1(IMPC)Mbp/Mmucd
	By 9.5 most Atp1b1^em1(IMPC)Mbp/Atp1b1^em1(IMPC)Mbp embryos display abnormal heart shape	Atp1b1^em1(IMPC)Mbp/Atp1b1^em1(IMPC)Mbp	C57BL/6NCrl-Atp1b1^em1(IMPC)Mbp/Mmucd

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