Gene Expression Image Detail

Reference

Figure

ID

J:386951 Guertin TM, et al., Onset of embryonic and placental defects coincide in 19 of 22 novel mid-gestation lethal murine knockout lines. Development. 2026 May 15;153(10):dev205276

Extended Data 4

MGI:8377007

Image

Caption

(A) E9.5 Tedc2-/- placentas do not exhibit defects. (B) Histological images of adjacent sections from a representative E9.5 Tedc2-/- placenta demonstrating normal development comparable to controls (n = 3). Dashed boxes indicate the LZ region shown at higher magnification in C. A slight reduction in the Gcm1/MCT4+ SynTII layer is observed in the Tedc2 KO placentas, but this could be due to mild developmental delay of the conceptus. (D) Images of the embryonic component of the conceptuses shown in B and C. Scale bars: 500 m.

Copyright

This image is from Guertin TM, Development 2026 May 15;153(10):dev205276, and is displayed under the terms of the Creative Commons Attribution 4.0 International License.

Associated
Assays

Label	Assay & Result Details (Gene Symbol)	Spatial Mapping
B +/- Gcm1	MGI:8350479 (Gcm1)
B -/- Gcm1	MGI:8350479 (Gcm1)
B +/- Tfeb	MGI:8350480 (Tfeb)
B -/- Tfeb	MGI:8350480 (Tfeb)
B +/- Tpbpa	MGI:8350481 (Tpbpa)
B -/- Tpbpa	MGI:8350481 (Tpbpa)
C +/- Gcm1	MGI:8350479 (Gcm1)
C -/- Gcm1	MGI:8350479 (Gcm1)
C +/- MCT1	MGI:8350550 (Slc16a1)
C -/- MCT1	MGI:8350550 (Slc16a1)
C +/- MCT4	MGI:8350556 (Slc16a3)
C -/- MCT4	MGI:8350556 (Slc16a3)
C +/- Merge	MGI:8351304 (Emcn) MGI:8350550 (Slc16a1) MGI:8350556 (Slc16a3)
C -/- Merge	MGI:8351304 (Emcn) MGI:8350550 (Slc16a1) MGI:8350556 (Slc16a3)
C +/- Tfeb	MGI:8350480 (Tfeb)
C -/- Tfeb	MGI:8350480 (Tfeb)