About   Help   FAQ
Mammalian Phenotype Ontology Annotations
Query Results - Summary
113 genotypes with 114 annotations displayed of selected term and subterms
Searched Term: increased squamous cell carcinoma incidence
Allelic Composition
(Genetic Background)		 Annotated Term Reference
Aicdatm1(cre)Mnz/Aicda+
Gt(ROSA)26Sortm2(sb11)Njen/Gt(ROSA)26Sor+
TgTn(sb-T2/Onc2)6070Njen/0
(involves: 129 * 129P2/OlaHsd * C57BL/6 * C57BL/6J) 		increased skin squamous cell carcinoma incidence J:153656
Atp2a2tm1Ges/Atp2a2+
(involves: 129X1/SvJ * Black Swiss) 		increased squamous cell carcinoma incidence J:69754
Atp2c1tm1Ges/Atp2c1+
(involves: 129X1/SvJ * Black Swiss) 		increased squamous cell carcinoma incidence J:124662
AurkaGt(XQ0149)Wtsi/Aurka+
(involves: 129P2/OlaHsd * C57BL/6) 		increased squamous cell carcinoma incidence J:143099
Bap1em1Test/Bap1+
(involves: FVB) 		increased squamous cell carcinoma incidence J:213725
Bmpr1atm2.1Bhr/Bmpr1atm2.1Bhr
Ctnnb1tm1Mmt/Ctnnb1+
Krt14tm1.1(cre)Wbm/Krt14+
(involves: 129P2/OlaHsd * 129S7/SvEvBrd * 129X1/SvJ) 		increased squamous cell carcinoma incidence J:199091
Brca1tm1Cxd/Brca1tm2Cxd
Tg(KRT5-cre)5132Jlj/0
(involves: 129S6/SvEvTac * C57BL/6) 		increased squamous cell carcinoma incidence J:85354
Brca1tm1Cxd/Brca1tm2Cxd
Tg(KRT5-cre)5132Jlj/0
Tg(KRT5-E2F1)2Dgj/0
(involves: 129S6/SvEvTac * C57BL/6 * SJL) 		increased squamous cell carcinoma incidence J:85354
Brca1tm1Cxd/Brca1tm2Cxd
Tg(KRT5-E2F1)2Dgj/0
(involves: 129S6/SvEvTac * C57BL/6 * SJL) 		increased squamous cell carcinoma incidence J:85354
Brca1tm2Cxd/Brca1+
Tg(KRT5-E2F1)2Dgj/0
(involves: 129S6/SvEvTac * C57BL/6 * SJL) 		increased squamous cell carcinoma incidence J:85354
Cdh1tm1Jjon/Cdh1+
Trp53tm1Brn/Trp53tm1Brn
Tg(KRT14-cre)8Brn/0
(involves: 129P2/OlaHsd * FVB/N) 		increased squamous cell carcinoma incidence J:116152
Cdh1tm2Kem/Cdh1+
Smad4tm2.1Cxd/Smad4tm2.1Cxd
Trp53tm1Brn/Trp53tm1Brn
Tg(Pdx1-cre)6Tuv/0
(involves: 129 * C57BL/6 * FVB/N) 		increased squamous cell carcinoma incidence J:212549
Cdkn1atm1Tyj/Cdkn1atm1Tyj
(involves: 129/Sv * 129S2/SvPas * C57BL/6) 		increased squamous cell carcinoma incidence J:72780
Cdkn1atm1Tyj/Cdkn1atm1Tyj
Cdkn2atm1Rdp/Cdkn2atm1Rdp
(involves: 129/Sv * 129S2/SvPas * C57BL/6 * C57BL/6J * SJL) 		increased squamous cell carcinoma incidence J:72780
Cdkn2atm1Cjs/Cdkn2atm1Cjs
(involves: 129X1/SvJ * C57BL/6 * NIH/OlaHsd) 		increased squamous cell carcinoma incidence J:93298
Cdkn2atm1Cjs/Cdkn2atm1Cjs
Tacstd2tm1Lsm/Tacstd2tm1Lsm
(involves: 129X1/SvJ * C57BL/6) 		increased skin squamous cell carcinoma incidence J:182647
Cdkn2atm1Rdp/Cdkn2atm1Rdp
(involves: 129/Sv * C57BL/6 * C57BL/6J * SJL) 		increased squamous cell carcinoma incidence J:72780
Cebpatm1Gonz/Cebpatm1Gonz
Tg(KRT5-cre)5132Jlj/0
(involves: 129X1/SvJ * C57BL/6 * DBA/2J) 		increased squamous cell carcinoma incidence J:123139
Chuktm2Yhu/Chuktm2Yhu
(involves: 129S1/Sv * 129X1/SvJ * C57BL/6) 		increased skin squamous cell carcinoma incidence J:197037
Chuktm2Yhu/Chuktm2Yhu
Tg(Lor-CHUK)8Yhu/0
(involves: 129S1/Sv * 129X1/SvJ * FVB/N) 		increased lung squamous cell carcinoma incidence J:197037
Chuktm2Yhu/Chuktm2Yhu
Tg(Lor-CHUK)8Yhu/0
(involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * FVB/N) 		increased squamous cell carcinoma incidence J:197037
Col1a1tm1(tetO-YAP1*)Fcam/Col1a1+
Gt(ROSA)26Sortm1(rtTA,EGFP)Nagy/Gt(ROSA)26Sor+
Tg(KRT14-cre)1Amc/0
(involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * C57BL/6 * CBA) 		increased skin squamous cell carcinoma incidence J:171057
Ddb2tm1Vri/Ddb2+
(involves: 129P2/Ola * SKH1) 		increased squamous cell carcinoma incidence J:103406
Ddb2tm1Vri/Ddb2tm1Vri
(involves: 129P2/Ola * SKH1) 		increased squamous cell carcinoma incidence J:103406
Del(4D4Mit190-D4Mit51)2Aam/+
(involves: 129S7/SvEvBrd) 		increased squamous cell carcinoma incidence J:121726
Dicer1tm1Snj/Dicer1tm1Snj
Trp53tm1Brn/Trp53tm1Brn
Tg(KRT5-cre/PGR)1Der/0
(involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6N * FVB/N * ICR) 		increased skin squamous cell carcinoma incidence J:216813
Grhl3tm1Jane/Grhl3+
Ptentm1Mak/Pten+
(involves: 129P2/OlaHsd * 129S1/Sv) 		increased skin squamous cell carcinoma incidence J:178952
Grhl3tm1Jane/Grhl3tm3.1Jane
Tg(KRT14-cre)8Brn/0
(involves: 129S1/Sv * C57BL/6 * FVB/N) 		increased skin squamous cell carcinoma incidence J:178952
Gt(ROSA)26Sortm1(cre/ERT)Nat/Gt(ROSA)26Sor+
Ptentm1Hwu/Ptentm1Hwu
(involves: 129 * 129S4/SvJae * BALB/c * C57BL/6) 		increased skin squamous cell carcinoma incidence J:130367
Gt(ROSA)26Sortm1(MAML1)Wsp/Gt(ROSA)26Sor+
Tg(Tagln-cre)1Jjl/0
(involves: CD-1 * FVB/N) 		increased squamous cell carcinoma incidence J:112093
Gt(ROSA)26Sortm1(sb11)Njen/Gt(ROSA)26Sor+
Hprt1tm1(sb-Onco-Array)Peli/Y
(involves: 129S7/SvEvBrd) 		increased skin squamous cell carcinoma incidence J:166283
Gt(ROSA)26Sortm1(sb11)Njen/Gt(ROSA)26Sor+
Hprt1tm1(sb-Onco-Array)Peli/Hprt1+
(involves: 129S7/SvEvBrd) 		increased skin squamous cell carcinoma incidence J:166283
Gt(ROSA)26Sortm1(sb11)Njen/Gt(ROSA)26Sor+
TgTn(sb-T2/Onc3)12740Njen/0
(involves: C3H * C57BL/6J) 		increased skin squamous cell carcinoma incidence J:153656
increased squamous cell carcinoma incidence J:153656
Hic1tm1Sbb/Hic1+
(involves: 129S4/SvJae * C57BL/6) 		increased squamous cell carcinoma incidence J:81448
Hrhr/Hrhr
Msh2tm1Htr/Msh2tm1Htr
(involves: 129P2/OlaHsd) 		increased skin squamous cell carcinoma incidence J:79734
Hrhr/Hrhr
Msh2tm1Htr/Msh2tm1Htr
Xpatm1Tnka/Xpatm1Tnka
(involves: 129P2/OlaHsd * C57BL/6 * CBA) 		increased skin squamous cell carcinoma incidence J:79734
Hrhr/Hrhr
Tg(KRT14-Birc5)19Gros/0
(involves: C3H * C57BL/6 * SKH1) 		increased squamous cell carcinoma incidence J:95011
Krastm2Tyj/Kras+
(involves: 129S2/SvPas) 		increased squamous cell carcinoma incidence J:129627
Krastm2Tyj/Kras+
Trp53tm1Glo/Trp53+
(involves: 129S2/SvPas * 129S7/SvEvBrd) 		increased squamous cell carcinoma incidence J:129627
Krastm4Tyj/Kras+
Smad4tm2.1Cxd/Smad4tm2.1Cxd
Tg(Krt1-15-cre/PGR*)22Cot/0
(involves: 129S4/SvJae * 129S6/SvEvTac * C57BL/6 * C57BL/6J * SJL/J) 		increased skin squamous cell carcinoma incidence J:203922
Krastm4Tyj/Kras+
Stk11tm1.1Rdp/Stk11tm1.1Rdp
(involves: 129S4/SvJae * 129S6/SvEvTac * C57BL/6 * FVB/N) 		increased lung squamous cell carcinoma incidence J:124682
Krastm4Tyj/Kras+
Stk11tm1.1Rdp/Stk11tm1.2Rdp
(involves: 129S4/SvJae * 129S6/SvEvTac * C57BL/6 * FVB/N) 		increased lung squamous cell carcinoma incidence J:124682
Krastm4Tyj/Kras+
Trp53tm1Brn/Trp53tm1Brn
Tg(KRT5-cre/PGR)1Der/?
(involves: 129/Sv * 129P2/OlaHsd * C57BL/6 * FVB * ICR) 		increased squamous cell carcinoma incidence J:124222
Krastm4Tyj/Kras+
Trp53tm1Brn/Trp53tm1Brn
Tg(KRT14-cre/ERT)20Efu/0
(involves: 129P2/OlaHsd * 129S4/SvJae * CD-1) 		increased skin squamous cell carcinoma incidence J:172048
Krt14tm1.1(cre)Wbm/Krt14+
Tg(KRT14-Snai1)1Efu/0
Trp53tm1Brn/Trp53tm1Brn
(involves: 129P2/OlaHsd * CD-1) 		increased skin squamous cell carcinoma incidence J:229072
Ly6atm2(RUNX1)Grau/Ly6a+
(involves: 129X1/SvJ * C57BL/6J) 		increased squamous cell carcinoma incidence J:93408
Mc1re/Mc1re
Xpctm1Brd/Xpctm1Brd
Tg(KRT14-Kitl)1Takk/0
(involves: 129S7/SvEvBrd * C57BL/6 * SJL) 		increased squamous cell carcinoma incidence J:112959
Mdm2tm3.1Glo/Mdm2tm3.1Glo
Trp53tm3.1Glo/Trp53+
(B6.129S-Mdm2tm3.1Glo Trp53tm3.1Glo) 		increased squamous cell carcinoma incidence J:164201
Mdm2tm4.1Glo/Mdm2tm4.1Glo
Trp53tm3.1Glo/Trp53+
(B6.129S-Mdm2tm4.1Glo Trp53tm3.1Glo) 		increased squamous cell carcinoma incidence J:164201
Mettm1Gvw/Met+
(involves: 129 * C57BL/6J) 		increased squamous cell carcinoma incidence J:94722
Mettm4Gvw/Met+
(involves: 129 * C57BL/6J * FVB/N) 		increased squamous cell carcinoma incidence J:151890
Mlh1tm1Rak/Mlh1+
(involves: 129P2/OlaHsd * C57BL/6) 		increased squamous cell carcinoma incidence J:53451
Mmp9tm1Tvu/Mmp9tm1Tvu
Tg(KRT14-HPV16)wt1Dh/0
(involves: 129S6/SvEvTac * C57BL/6 * DBA/2 * FVB/N) 		increased skin squamous cell carcinoma incidence J:65699
Msh2tm1Whl/Msh2tm1Whl
(involves: 129P2/OlaHsd * C57BL/6J) 		increased squamous cell carcinoma incidence J:79016
Nbnem3Jpt/Nbnem3Jpt
Trp53tm1Tyj/Trp53tm1Tyj
(involves: 129S2/SvPas) 		increased squamous cell carcinoma incidence J:251434
Nbnem4Jpt/Nbnem4Jpt
Trp53tm1Tyj/Trp53tm1Tyj
(involves: 129S2/SvPas) 		increased squamous cell carcinoma incidence J:251434
Nkx2-9tm1Jlck/Nkx2-9tm1Jlck
(involves: 129/Sv * C57BL/6 * SJL) 		increased squamous cell carcinoma incidence J:115581
Nr1h2tm1.1Gstr/Nr1h2tm1.1Gstr
Nr1h3tm1.1Gstr/Nr1h3tm1.1Gstr
(involves: 129S1/Sv * 129X1/SvJ * C57BL/6) 		increased lung squamous cell carcinoma incidence J:234268
Otulinem1Gvl/Otulintm1c(EUCOMM)Hmgu
Tg(KRT14-cre)1Cgn/0
(involves: C57BL/6 * C57BL/6J * C57BL/6N * DBA/2) 		increased squamous cell carcinoma incidence J:312394
Otulintm1c(EUCOMM)Hmgu/Otulintm1c(EUCOMM)Hmgu
Tg(KRT14-cre)1Cgn/0
(involves: C57BL/6 * C57BL/6N * DBA/2) 		increased skin squamous cell carcinoma incidence J:312394
Perptm2Att/Perptm2Att
Tg(KRT14-cre/ERT2)1Ipc/0
(involves: 129S4/SvJae) 		increased skin squamous cell carcinoma incidence J:167545
Plk1Gt(RRR358)Byg/Plk1+
(involves: 129P2/OlaHsd * C57BL/6) 		increased squamous cell carcinoma incidence J:142593
Pold1tm1Bdp/Pold1tm1Bdp
(involves: 129S1/Sv * 129X1/SvJ * C57BL/6) 		increased squamous cell carcinoma incidence J:100685
Polhtm1.1Rak/Polhtm1.1Rak
(involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6) 		increased squamous cell carcinoma incidence J:105034
Ptentm1Hwu/Ptentm1Hwu
Tg(Fabp1-cre)1Jig/0
(involves: 129S4/SvJae * FVB/N) 		increased squamous cell carcinoma incidence J:106662
Ptentm1Hwu/Ptentm1Hwu
Tgfbr1tm1.1Karl/Tgfbr1tm1.1Karl
Tg(KRT14-cre/ERT)20Efu/0
(involves: 129 * 129S4/SvJae * C57BL/6 * CD-1 * FVB/N) 		increased squamous cell carcinoma incidence J:209026, J:194652
Ptentm2Mak/Ptentm2Mak
Tg(SFTPC-rtTA)5Jaw/0
Tg(tetO-cre)1Jaw/0
(involves: 129 * 129P2/OlaHsd * C57BL/6 * C57BL/6J) 		increased lung squamous cell carcinoma incidence J:127405
Rb1tm2Brn/Rb1tm2Brn
Trp53tm1Brn/Trp53tm1Brn
Tg(MMTV-cre)105Ayn/0
(FVB.Cg-Trp53tm1Brn Rb1tm2Brn Tg(MMTV-cre)105Ayn) 		increased squamous cell carcinoma incidence J:165292
Rgsc682/Rgsc682+
(involves: C57BL/6JJcl * DBA/2JJcl) 		increased squamous cell carcinoma incidence J:133634
Rgsc814/Rgsc814+
(involves: C57BL/6JJcl * DBA/2JJcl) 		increased squamous cell carcinoma incidence J:133634
Rgsc1049/Rgsc1049+
(involves: C57BL/6JJcl * DBA/2JJcl) 		increased squamous cell carcinoma incidence J:133634
Rint1tm1Whl/Rint1+
(Not Specified) 		increased skin squamous cell carcinoma incidence J:122805
SfnEr/Sfn+
(involves: 129/Sv * C57BL/6) 		increased squamous cell carcinoma incidence J:12025
Ssbp2tm1Lana/Ssbp2tm1Lana
(involves: 129S/SvEv * C57BL/6) 		increased squamous cell carcinoma incidence J:162035
Stk11tm1.1Rdp/Stk11tm1.1Rdp
Tg(KRT14-cre)1Ipc/0
(involves: 129S6/SvEvTac * C57BL/6 * FVB/N * SJL) 		increased squamous cell carcinoma incidence J:131037
Taf4tm1Idvd/Taf4tm1Idvd
Tg(KRT14-cre/ERT2)1Ipc/0
(involves: C57BL/6 * SJL) 		increased squamous cell carcinoma incidence J:124111
Terf1tm1.1Blas/Terf1tm1.1Blas
Tg(KRT5-cre)1Tak/0
Trp53tm1Tyj/Trp53tm1Tyj
(involves: 129 * C3H * C57BL/6 * SJL) 		increased skin squamous cell carcinoma incidence J:152077
Tg(K5-Ptgs2)19Kmd/0
(involves: NMRI) 		increased squamous cell carcinoma incidence J:79071
Tg(K5-Ptgs2)667Kmd/0
(involves: NMRI) 		increased squamous cell carcinoma incidence J:79071
Tg(KRT5-Akt1*)Jmpa/0
(involves: C57BL/6 * DBA/2 * DBA/2J * FVB/N) 		increased squamous cell carcinoma incidence J:144831
Tg(KRT5-rtTA)#Glk/0
Tg(tetO/CMV-Dek,-luc)317Siwe/0
(involves: FVB/N) 		increased squamous cell carcinoma incidence J:261249
Tg(KRT5-Terf2)PMBlas/Y
(involves: C57BL/6 * CBA) 		increased skin squamous cell carcinoma incidence J:102653
Tg(KRT5-Terf2)POBlas/0
(involves: C57BL/6 * CBA) 		increased skin squamous cell carcinoma incidence J:102653
Tg(KRT14-cre)8Brn/0
Tg(KRT5-Akt1*)Jmpa/0
Trp53tm1Brn/Trp53tm1Brn
(involves: 129P2/OlaHsd * C57BL/6 * DBA/2 * DBA/2J * FVB/N) 		increased squamous cell carcinoma incidence J:144831
Tg(KRT14-Fyn*)aJsey/0
(involves: C57BL/6 * CBA) 		increased skin squamous cell carcinoma incidence J:155536
Tg(KRT14-Fyn*)aJsey/0
(involves: C57BL/6 * CBA * FVB/N) 		increased skin squamous cell carcinoma incidence J:155536
Tg(KRT14-HPV8)9Vuc/0
(FVB.Cg-Tg(KRT14-HPV8)9Vuc) 		increased skin squamous cell carcinoma incidence J:96784
Tg(KRT14-HPV8)85Vuc/0
(FVB.Cg-Tg(KRT14-HPV8)85Vuc) 		increased skin squamous cell carcinoma incidence J:96784
Tg(KRT14-HPV8)#Vuc/0
(involves: C57BL/6 * DBA * FVB/N) 		increased skin squamous cell carcinoma incidence J:96784
Tg(KRT14-HPV16)wt1Dh/0
(FVB.Cg-Tg(KRT14-HPV16)wt1Dh/Nci) 		increased skin squamous cell carcinoma incidence J:65699
Tg(KRT14-HPV16)wt1Dh/0
(either: FVB.Cg-Tg(KRT14-HPV16)wt1Dh or (involves: C57BL/6 * DBA/2 * FVB/N)) 		increased skin squamous cell carcinoma incidence J:20130
Tg(KRT14-HPV16E7)2304Plam/0
(involves: FVB/N) 		increased skin squamous cell carcinoma incidence J:86018
Tg(KRT14-HPV16E7)2326Plam/0
(involves: FVB/N) 		increased skin squamous cell carcinoma incidence J:86018
Tg(KRT14-Snai1)1Efu/0
(involves: CD-1) 		increased skin squamous cell carcinoma incidence J:229072
Tg(Mdm2)1Snj/0
Trp53tm1Brd/Trp53tm1Brd
(involves: 129S7/SvEvBrd * C57BL/6) 		increased squamous cell carcinoma incidence J:51661
Tg(MMTVTGFA)29Rjc/0
(involves: C57BL/6 * DBA/2) 		increased squamous cell carcinoma incidence J:72080
Thbs1tm1Hyn/Thbs1tm1Hyn
Trp53tm1Tyj/Trp53+
(involves: 129S2/SvPas * C57BL/6) 		increased squamous cell carcinoma incidence J:72391
Tiam1tm1Jgc/Tiam1tm1Jgc
(involves: 129P2/OlaHsd * FVB) 		increased squamous cell carcinoma incidence J:77148
Trim62tm1Akil/Trim62tm1Akil
(involves: 129S/SvEv * C57BL/6) 		increased squamous cell carcinoma incidence J:204336
Trp53tm1Brn/Trp53tm1Brn
Tg(KRT5-cre/PGR)1Der/0
(involves: 129P2/OlaHsd * C57BL/6N * FVB/N * ICR) 		increased skin squamous cell carcinoma incidence J:216813
Trp53tm1Brn/Trp53tm1Brn
Tg(KRT14-cre)8Brn/0
(involves: 129P2/OlaHsd * FVB/N) 		increased squamous cell carcinoma incidence J:116152
Trp53tm1Brn/Trp53tm1Brn
Tg(MMTV-cre)105Ayn/0
(FVB.Cg-Trp53tm1Brn Tg(MMTV-cre)105Ayn) 		increased squamous cell carcinoma incidence J:165292
Trp53tm1Glo/Trp53+
(involves: 129S7/SvEvBrd * C57BL/6) 		increased squamous cell carcinoma incidence J:61683
Trp53tm1Glo/Trp53+
(involves: 129S7/SvEvBrd) 		increased squamous cell carcinoma incidence J:129627
Trp53tm1Tyj/Trp53+
(involves: 129S2/SvPas * C57BL/6) 		increased squamous cell carcinoma incidence J:72391
Trp53tm1Tyj/Trp53+
Trp63tm1Fmc/Trp63+
(involves: 129S2/SvPas * 129S4/SvJae * C57BL/6) 		increased squamous cell carcinoma incidence J:98958
Trp53tm1Tyj/Trp53tm1Tyj
(involves: 129S2/SvPas * C57BL/6) 		increased squamous cell carcinoma incidence J:72391
Trp53tm3.1Tyj/Trp53+
(involves: 129S4/SvJae) 		increased squamous cell carcinoma incidence J:95316
Trp53bp2tm1Xlu/Trp53bp2+
(involves: 129S6/SvEvTac * C57BL/6J) 		increased squamous cell carcinoma incidence J:108701
Trp63tm1Fmc/Trp63+
(involves: 129S4/SvJae * C57BL/6) 		increased squamous cell carcinoma incidence J:98958
Trp63tm1Fmc/Trp63+
Trp73tm1Fmc/Trp73+
(involves: 129S4/SvJae * C57BL/6) 		increased squamous cell carcinoma incidence J:98958
Tusc2tm1Avi/Tusc2tm1Avi
(involves: 129S1/Sv * C57BL/6J) 		increased squamous cell carcinoma incidence J:119985
Xpatm1Tnka/Xpatm1Tnka
(involves: C57BL/6 * CBA) 		increased skin squamous cell carcinoma incidence J:28709
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
04/30/2024
MGI 6.23 		The Jackson Laboratory