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Gene Expression Data
Assay Details
Assay
Reference: J:386951 Guertin TM, et al., Onset of embryonic and placental defects coincide in 19 of 22 novel mid-gestation lethal murine knockout lines. Development. 2026 May 15;153(10):dev205276
Assay type: RNA in situ
MGI Accession ID: MGI:8350480
Gene symbol: Tfeb
Gene name: transcription factor EB
Probe: Tfeb cDNA
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 2E: embryonic day 9.5 (more )
Structure Cell Type Level Pattern Image Note
TS15: labyrinthine zone syncytiotrophoblast cell Present Regionally restricted 2E Expression is seen in a subset of trophoblasts--SynTI cells and precursors.
Specimen E8.5 - 3C; Ext1B/E: embryonic day 8.5 (more )
Note: Littermate control.
Structure Cell Type Level Pattern Image Note
TS13: labyrinthine zone syncytiotrophoblast cell Present Regionally restricted 3C E8.5 , Extended Data 1E Tfeb E8.5 , Extended Data 1B E8.5 Expression is seen in SynTI cells and precursors. Uniform expression of the chorion is displayed, except for the basal-most layer.
Specimen E8.75 - 3C; Ext1B/E: embryonic day 8.75 (more )
Note: Littermate control.
Structure Cell Type Level Pattern Image Note
TS13: labyrinthine zone syncytiotrophoblast cell Present Regionally restricted Extended Data 1E Tfeb E8.75 , 3C E8.75 , Extended Data 1B E8.75 Expression is seen in SynTI cells and precursors.
Specimen E9.0 - Ext1B/E: embryonic day 9.0 (more )
Note: Littermate control.
Structure Cell Type Level Pattern Image Note
TS14: labyrinthine zone syncytiotrophoblast cell Present Regionally restricted Extended Data 1B E9.0 , Extended Data 1E Tfeb E9.0 Expression is seen in SynTI cells and precursors.
Specimen E9.25 - 3C; 6C Chp1 +/-; Ext1B/E; Ext 8B/C: embryonic day 9.25; Chp1em1(IMPC)Tcp/Chp1+ (more )
Structure Cell Type Level Pattern Image Note
TS14: labyrinthine zone syncytiotrophoblast cell Present Regionally restricted Extended Data 8B +/- Tfeb , Extended Data 8C +/- Tfeb , 3C E9.25 , 6C Chp1+/- Tfeb , Extended Data 1E Tfeb E9.25 , Extended Data 1B E9.25 Expression is seen in SynTI cells and precursors.
Specimen E9.5 - Ext1B/E: embryonic day 9.5 (more )
Note: Littermate control.
Structure Cell Type Level Pattern Image Note
TS15: labyrinthine zone syncytiotrophoblast cell Present Regionally restricted Extended Data 1B E9.5 , Extended Data 1E Tfeb E9.5 Expression is seen in SynTI cells and precursors.
Specimen E9.75 - 3C; 6B Got2 +/-; Ext1B/E; Ext14B/C: embryonic day 9.75; Got2em1(IMPC)Mbp/Got2+ (more )
Structure Cell Type Level Pattern Image Note
TS15: labyrinthine zone syncytiotrophoblast cell Present Regionally restricted 6B Got+/- Tfeb , Extended Data 14B +/- Tfeb , Extended Data 14C +/- Tfeb , Extended Data 1E Tfeb E9.75 , Extended Data 1B E9.75 , 3C E9.75 Expression is seen in SynTI cells and precursors.
Specimen E10.0 - Ext1B/E: embryonic day 10.0 (more )
Note: Littermate control.
Structure Cell Type Level Pattern Image Note
TS16: labyrinthine zone syncytiotrophoblast cell Present Regionally restricted Extended Data 1B E10.0 , Extended Data 1E Tfeb E10.0 Expression is seen in SynTI cells and precursors.
Specimen E10.5 - 3C; 6F Traf7 +/-; Ext1B/E; Ext19E/F: embryonic day 10.5; Traf7em1(IMPC)Tcp/Traf7+ (more )
Structure Cell Type Level Pattern Image Note
TS17: labyrinthine zone syncytiotrophoblast cell Present Regionally restricted Extended Data 1B E10.5 , 6F Traf7+/- Tfeb , Extended Data 1E Tfeb E10.5 , Extended Data 19F +/- Tfeb , 3C E10.5 , Extended Data 19E +/- Tfeb Expression is seen in SynTI cells and precursors. Expression is seen in an expanded region, with expressing cells interspersed with non-expressing cells.
Specimen 6A Gmeb2 +/-; Ext11B/C: embryonic day 9.5; Gmeb2em1(IMPC)J/Gmeb2+ (more )
Structure Cell Type Level Pattern Image Note
TS15: labyrinthine zone syncytiotrophoblast cell Present Regionally restricted Extended Data 11C +/- Tfeb , Extended Data 11B +/- Tfeb , 6A Gmemb2+/- Tfeb Expression is seen in SynTI cells and precursors.
Specimen 6A Gmeb2 -/-; Ext11B/C: embryonic day 9.5; Gmeb2em1(IMPC)J/Gmeb2em1(IMPC)J (more )
Structure Cell Type Level Pattern Image Note
TS15: labyrinthine zone syncytiotrophoblast cell Present Regionally restricted Extended Data 11B -/- Tfeb , 6A Gmemb2-/- Tfeb , Extended Data 11C -/- Tfeb Expression is seen in SynTI cells and precursors. In mutants the density of the expressing cells remains the same but the region fails to expand, remaining a thin layer.
Specimen 6B Got2 -/-: embryonic day 9.5; Got2em1(IMPC)Mbp/Got2em1(IMPC)Mbp (more )
Structure Cell Type Level Pattern Image Note
TS15: labyrinthine zone syncytiotrophoblast cell Present Regionally restricted 6B Got-/- Tfeb , Extended Data 14C -/- Tfeb , Extended Data 14B -/- Tfeb Expression is seen in SynTI cells and precursors. In mutants the density of the expressing cells remains the same but the region fails to expand, remaining a thin layer.
Specimen 6C Chp1 -/-; Ext8B/C: embryonic day 9.5; Chp1em1(IMPC)Tcp/Chp1em1(IMPC)Tcp (more )
Structure Cell Type Level Pattern Image Note
TS15: labyrinthine zone syncytiotrophoblast cell Present Regionally restricted 6C Chp1-/- Tfeb , Extended Data 8C -/- #2 Tfeb , Extended Data 8B -/- #2 Tfeb Expression is seen in SynTI cells and precursors. In mutants the density of the expressing cells remains the same but the region fails to expand, remaining a thin layer.
Specimen 6D Exoc3l4 +/-; Ext20D/E: embryonic day 10.5; Exoc3l4em1(IMPC)J/Exoc3l4+ (more )
Structure Cell Type Level Pattern Image Note
TS17: labyrinthine zone syncytiotrophoblast cell Present Regionally restricted 6D Exoc3l4+/- Tfeb , Extended Data 20E +/- Tfeb , Extended Data 20D +/- Tfeb Expression is seen in SynTI cells and precursors.
Specimen 6D Exoc3l4 -/-; Ext20D/E: embryonic day 10.5; Exoc3l4em1(IMPC)J/Exoc3l4em1(IMPC)J (more )
Structure Cell Type Level Pattern Image Note
TS17: labyrinthine zone syncytiotrophoblast cell Present Regionally restricted Extended Data 20D -/- Tfeb , 6D Exoc3l4-/- Tfeb , Extended Data 20E -/- Tfeb Expression is seen in SynTI cells and precursors. In mutants this layer is markedly reduced.
Specimen 6E Usb1 +/-; Ext22E/F: embryonic day 10.5; Usb1em1(IMPC)Bay/Usb1+ (more )
Structure Cell Type Level Pattern Image Note
TS17: labyrinthine zone syncytiotrophoblast cell Present Regionally restricted Extended Data 22F +/- Tfeb , 6E Usb1+/- Tfeb , Extended Data 22E +/- Tfeb Expression is seen in SynTI cells and precursors.
Specimen 6E Usb1 -/-; Ext22E/F: embryonic day 10.5; Usb1em1(IMPC)Bay/Usb1em1(IMPC)Bay (more )
Structure Cell Type Level Pattern Image Note
TS17: labyrinthine zone syncytiotrophoblast cell Present Regionally restricted 6E Usb1-/- Tfeb , Extended Data 22E -/- Tfeb , Extended Data 22F -/- Tfeb Expression is seen in SynTI cells and precursors. In mutants this layer is reduced.
Specimen 6F Traf7 -/-; Ext19E/F: embryonic day 10.5; Traf7em1(IMPC)Tcp/Traf7em1(IMPC)Tcp (more )
Structure Cell Type Level Pattern Image Note
TS17: labyrinthine zone syncytiotrophoblast cell Present Regionally restricted Extended Data 19E -/- Tfeb , 6F Traf7-/- Tfeb , Extended Data 19F -/- Tfeb Expression is seen in SynTI cells and precursors. In mutants this layer is reduced in thickness but displays elevated signal intensity, suggesting an increased cell density.
Specimen Atp1b1 +/- E9.5: embryonic day 9.5; Atp1b1em1(IMPC)Mbp/Atp1b1+ (more )
Structure Cell Type Level Pattern Image Note
TS15: labyrinthine zone syncytiotrophoblast cell Present Regionally restricted Extended Data 2C +/- Tfeb , Extended Data 2B +/- Tfeb Expression is seen in SynTI cells and precursors.
Specimen Atp1b1 -/- E9.5: embryonic day 9.5; Atp1b1em1(IMPC)Mbp/Atp1b1em1(IMPC)Mbp (more )
Structure Cell Type Level Pattern Image Note
TS15: labyrinthine zone syncytiotrophoblast cell Present Regionally restricted Extended Data 2C -/- Tfeb , Extended Data 2B -/- Tfeb Expression is seen in SynTI cells and precursors; in the mutant the size of this layer is comparable to that seen in the controls.
Specimen Ehbp1 +/- E9.5: embryonic day 9.5; Ehbp1em1(IMPC)J/Ehbp1+ (more )
Structure Cell Type Level Pattern Image Note
TS15: labyrinthine zone syncytiotrophoblast cell Present Regionally restricted Extended Data 3B +/- Tfeb , Extended Data 3C +/- Tfeb Expression is seen in SynTI cells and precursors.
Specimen Ehbp1 -/- E9.5: embryonic day 9.5; Ehbp1em1(IMPC)J/Ehbp1em1(IMPC)J (more )
Structure Cell Type Level Pattern Image Note
TS15: labyrinthine zone syncytiotrophoblast cell Present Regionally restricted Extended Data 3C -/- Tfeb , Extended Data 3B -/- Tfeb Expression is seen in SynTI cells and precursors; in the mutant the size of this layer is comparable to that seen in the controls. (A slight reduction in the layer was observed but was attributed to the developmental delay of the conceptus.)
Specimen Tedc2 +/- E9.5: embryonic day 9.5; Tedc2em1(IMPC)J/Tedc2+ (more )
Structure Cell Type Level Pattern Image Note
TS15: labyrinthine zone syncytiotrophoblast cell Present Regionally restricted Extended Data 4B +/- Tfeb , Extended Data 4C +/- Tfeb Expression is seen in SynTI cells and precursors.
Specimen Tedc2 -/- E9.5: embryonic day 9.5; Tedc2em1(IMPC)J/Tedc2em1(IMPC)J (more )
Structure Cell Type Level Pattern Image Note
TS15: labyrinthine zone syncytiotrophoblast cell Present Regionally restricted Extended Data 4B -/- Tfeb , Extended Data 4C -/- Tfeb Expression is seen in SynTI cells and precursors; in the mutant the size of this layer is comparable to that seen in the controls.
Specimen Zmym2 +/- E9.5: embryonic day 9.5; Zmym2em1(IMPC)J/Zmym2+ (more )
Structure Cell Type Level Pattern Image Note
TS15: labyrinthine zone syncytiotrophoblast cell Present Regionally restricted Extended Data 5B +/- Tfeb , Extended Data 5C +/- Tfeb Expression is seen in SynTI cells and precursors.
Specimen Zmym2 -/- E9.5: embryonic day 9.5; Zmym2em1(IMPC)J/Zmym2em1(IMPC)J (more )
Structure Cell Type Level Pattern Image Note
TS15: labyrinthine zone syncytiotrophoblast cell Present Regionally restricted Extended Data 5C -/- Tfeb , Extended Data 5B -/- Tfeb Expression is seen in SynTI cells and precursors; in the mutant the size of this layer is comparable to that seen in the controls.
Specimen Gcn1 +/- E9.5: embryonic day 9.5; Gcn1em1(IMPC)J/Gcn1+ (more )
Structure Cell Type Level Pattern Image Note
TS15: labyrinthine zone syncytiotrophoblast cell Present Regionally restricted Extended Data 6C +/- Tfeb , Extended Data 6B +/- Tfeb Expression is seen in SynTI cells and precursors.
Specimen Gcn1 -/- E9.5 - #1: embryonic day 9.5; Gcn1em1(IMPC)J/Gcn1em1(IMPC)J (more )
Structure Cell Type Level Pattern Image Note
TS15: labyrinthine zone syncytiotrophoblast cell Present Regionally restricted Extended Data 6B -/- #1 Tfeb , Extended Data 6C -/- #1 Tfeb Expression is seen in SynTI cells and precursors. In mutants the density of the expressing cells remains the same but the region fails to expand, remaining a thin layer.
Specimen Gcn1 -/- E9.5 - #2: embryonic day 9.5; Gcn1em1(IMPC)J/Gcn1em1(IMPC)J (more )
Structure Cell Type Level Pattern Image Note
TS15: labyrinthine zone syncytiotrophoblast cell Present Regionally restricted Extended Data 6C -/- #2 Tfeb , Extended Data 6B -/- #2 Tfeb Expression is seen in SynTI cells and precursors. In mutants the density of the expressing cells remains the same but the region fails to expand, remaining a thin layer.
Specimen Slc30a9 Control E9.5: embryonic day 9.5 (more )
Note: Littermate control.
Structure Cell Type Level Pattern Image Note
TS15: labyrinthine zone syncytiotrophoblast cell Present Regionally restricted Extended Data 7C Control Tfeb , Extended Data 7B Control Tfeb Expression is seen in SynTI cells and precursors.
Specimen Slc30a9 -/- E9.5: embryonic day 9.5; Slc30a9em1(IMPC)Bay/Slc30a9em1(IMPC)Bay (more )
Structure Cell Type Level Pattern Image Note
TS15: labyrinthine zone syncytiotrophoblast cell Present Regionally restricted Extended Data 7B -/- Tfeb , Extended Data 7C -/- Tfeb Expression is seen in SynTI cells and precursors. In mutants the density of the expressing cells remains the same but the region fails to expand, remaining a thin layer.
Specimen Chp1 -/- E9.5 - #1: embryonic day 9.5; Chp1em1(IMPC)Tcp/Chp1em1(IMPC)Tcp (more )
Structure Cell Type Level Pattern Image Note
TS15: labyrinthine zone syncytiotrophoblast cell Present Regionally restricted Extended Data 8C -/- #1 Tfeb , Extended Data 8B -/- #1 Tfeb Expression is seen in SynTI cells and precursors. In mutants the density of the expressing cells remains the same but the region fails to expand, remaining a thin layer.
Specimen Ppox +/- E9.5: embryonic day 9.5; Ppoxem1(IMPC)J/Ppox+ (more )
Structure Cell Type Level Pattern Image Note
TS15: labyrinthine zone syncytiotrophoblast cell Present Regionally restricted Extended Data 9C +/- Tfeb , Extended Data 9B +/- Tfeb Expression is seen in SynTI cells and precursors.
Specimen Ppox -/- E9.5: embryonic day 9.5; Ppoxem1(IMPC)J/Ppoxem1(IMPC)J (more )
Structure Cell Type Level Pattern Image Note
TS15: labyrinthine zone syncytiotrophoblast cell Present Regionally restricted Extended Data 9B -/- Tfeb , Extended Data 9C -/- Tfeb Expression is seen in SynTI cells and precursors. In mutants the density of the expressing cells remains the same but the region fails to expand, remaining a thin layer.
Specimen Urm1 +/- E9.5: embryonic day 9.5; Urm1em1(IMPC)J/Urm1+ (more )
Structure Cell Type Level Pattern Image Note
TS15: labyrinthine zone syncytiotrophoblast cell Present Regionally restricted Extended Data 10B +/- Tfeb , Extended Data 10C +/- Tfeb Expression is seen in SynTI cells and precursors.
Specimen Urm1 -/- E9.5: embryonic day 9.5; Urm1em1(IMPC)J/Urm1em1(IMPC)J (more )
Structure Cell Type Level Pattern Image Note
TS15: labyrinthine zone syncytiotrophoblast cell Present Regionally restricted Extended Data 10C -/- Tfeb , Extended Data 10B -/- Tfeb Expression is seen in SynTI cells and precursors. In mutants the density of the expressing cells remains the same but the region fails to expand, remaining a thin layer.
Specimen Kctd5 +/- E9.5: embryonic day 9.5; Kctd5em1(IMPC)J/Kctd5+ (more )
Structure Cell Type Level Pattern Image Note
TS15: labyrinthine zone syncytiotrophoblast cell Present Regionally restricted Extended Data 12B +/- Tfeb , Extended Data 12C +/- Tfeb Expression is seen in SynTI cells and precursors.
Specimen Kctd5 -/- E9.5: embryonic day 9.5; Kctd5em1(IMPC)J/Kctd5em1(IMPC)J (more )
Structure Cell Type Level Pattern Image Note
TS15: labyrinthine zone syncytiotrophoblast cell Present Regionally restricted Extended Data 12B -/- Tfeb , Extended Data 12C -/- Tfeb Expression is seen in SynTI cells and precursors. In mutants the density of the expressing cells remains the same but the region fails to expand, remaining a thin layer.
Specimen Rprd2 +/- E9.5: embryonic day 9.5; Rprd2em1(IMPC)J/Rprd2+ (more )
Structure Cell Type Level Pattern Image Note
TS15: labyrinthine zone syncytiotrophoblast cell Present Regionally restricted Extended Data 13C +/- Tfeb , Extended Data 13B +/- Tfeb Expression is seen in SynTI cells and precursors.
Specimen Rprd2 -/- E9.5: embryonic day 9.5; Rprd2em1(IMPC)J/Rprd2em1(IMPC)J (more )
Structure Cell Type Level Pattern Image Note
TS15: labyrinthine zone syncytiotrophoblast cell Present Regionally restricted Extended Data 13C -/- Tfeb , Extended Data 13B -/- Tfeb Expression is seen in SynTI cells and precursors. In mutants the density of the expressing cells remains the same but the region fails to expand, remaining a thin layer.
Specimen Arpc1a +/- E9.5: embryonic day 9.5; Arpc1aem1(IMPC)J/Arpc1a+ (more )
Structure Cell Type Level Pattern Image Note
TS15: labyrinthine zone syncytiotrophoblast cell Present Regionally restricted Extended Data 15C +/- Tfeb , Extended Data 15B +/- Tfeb Expression is seen in SynTI cells and precursors.
Specimen Arpc1a -/- E9.5: embryonic day 9.5; Arpc1aem1(IMPC)J/Arpc1aem1(IMPC)J (more )
Structure Cell Type Level Pattern Image Note
TS15: labyrinthine zone syncytiotrophoblast cell Present Regionally restricted Extended Data 15C -/- Tfeb , Extended Data 15B -/- Tfeb Expression is seen in SynTI cells and precursors; in the mutant the size of this layer is comparable to that seen in the controls.
Specimen Arpc1a +/- E10.5: embryonic day 10.5; Arpc1aem1(IMPC)J/Arpc1a+ (more )
Structure Cell Type Level Pattern Image Note
TS17: labyrinthine zone syncytiotrophoblast cell Present Regionally restricted Extended Data 15F +/- Tfeb , Extended Data 15E +/- Tfeb Expression is seen in SynTI cells and precursors.
Specimen Arpc1a -/- E10.5: embryonic day 10.5; Arpc1aem1(IMPC)J/Arpc1aem1(IMPC)J (more )
Structure Cell Type Level Pattern Image Note
TS17: labyrinthine zone syncytiotrophoblast cell Present Regionally restricted Extended Data 15E -/- Tfeb , Extended Data 15F -/- Tfeb Expression is seen in SynTI cells and precursors. In mutants the density of the expressing cells remains the same but the region fails to expand, remaining a thin layer.
Specimen Alg3 +/- E9.5: embryonic day 9.5; Alg3em1(IMPC)J/Alg3+ (more )
Structure Cell Type Level Pattern Image Note
TS15: labyrinthine zone syncytiotrophoblast cell Present Regionally restricted Extended Data 16C +/- Tfeb , Extended Data 16B +/- Tfeb Expression is seen in SynTI cells and precursors.
Specimen Alg3 -/- E9.5: embryonic day 9.5; Alg3em1(IMPC)J/Alg3em1(IMPC)J (more )
Structure Cell Type Level Pattern Image Note
TS15: labyrinthine zone syncytiotrophoblast cell Present Regionally restricted Extended Data 16C -/- Tfeb , Extended Data 16B -/- Tfeb Expression is seen in SynTI cells and precursors; in the mutant the size of this layer is comparable to that seen in the controls.
Specimen Alg3 +/- E10.5: embryonic day 10.5; Alg3em1(IMPC)J/Alg3+ (more )
Structure Cell Type Level Pattern Image Note
TS17: labyrinthine zone syncytiotrophoblast cell Present Regionally restricted Extended Data 16F +/- Tfeb , Extended Data 16E +/- Tfeb Expression is seen in SynTI cells and precursors.
Specimen Alg3 -/- E10.5: embryonic day 10.5; Alg3em1(IMPC)J/Alg3em1(IMPC)J (more )
Structure Cell Type Level Pattern Image Note
TS17: labyrinthine zone syncytiotrophoblast cell Present Regionally restricted Extended Data 16F -/- Tfeb , Extended Data 16E -/- Tfeb Expression is seen in SynTI cells and precursors. In mutants this layer is reduced in thickness but displays elevated signal intensity, suggesting an increased cell density.
Specimen Bltp2 +/- E9.5: embryonic day 9.5; Bltp2em1(IMPC)J/Bltp2+ (more )
Structure Cell Type Level Pattern Image Note
TS15: labyrinthine zone syncytiotrophoblast cell Present Regionally restricted Extended Data 17B +/- Tfeb , Extended Data 17C +/- Tfeb Expression is seen in SynTI cells and precursors.
Specimen Bltp2 -/- E9.5: embryonic day 9.5; Bltp2em1(IMPC)J/Bltp2em1(IMPC)J (more )
Structure Cell Type Level Pattern Image Note
TS15: labyrinthine zone syncytiotrophoblast cell Present Regionally restricted Extended Data 17C -/- Tfeb , Extended Data 17B -/- Tfeb Expression is seen in SynTI cells and precursors; in the mutant the size of this layer is comparable to that seen in the controls.
Specimen Bltp2 +/- E10.5: embryonic day 10.5; Bltp2em1(IMPC)J/Bltp2+ (more )
Structure Cell Type Level Pattern Image Note
TS17: labyrinthine zone syncytiotrophoblast cell Present Regionally restricted Extended Data 17E +/- Tfeb , Extended Data 17F +/- Tfeb Expression is seen in SynTI cells and precursors.
Specimen Bltp2 -/- E10.5: embryonic day 10.5; Bltp2em1(IMPC)J/Bltp2em1(IMPC)J (more )
Structure Cell Type Level Pattern Image Note
TS17: labyrinthine zone syncytiotrophoblast cell Present Regionally restricted Extended Data 17F -/- Tfeb , Extended Data 17E -/- Tfeb Expression is seen in SynTI cells and precursors. In 2 of 4 mutants examined this layer is markedly reduced and develops normally in another placenta..
Specimen Stt3b +/- E9.5: embryonic day 9.5; Stt3bem1(IMPC)J/Stt3b+ (more )
Structure Cell Type Level Pattern Image Note
TS15: labyrinthine zone syncytiotrophoblast cell Present Regionally restricted Extended Data 18C +/- Tfeb , Extended Data 18B +/- Tfeb Expression is seen in SynTI cells and precursors.
Specimen Stt3b -/- E9.5: embryonic day 9.5; Stt3bem1(IMPC)J/Stt3bem1(IMPC)J (more )
Structure Cell Type Level Pattern Image Note
TS15: labyrinthine zone syncytiotrophoblast cell Present Regionally restricted Extended Data 18C -/- Tfeb , Extended Data 18B -/- Tfeb Expression is seen in SynTI cells and precursors; in the mutant the size of this layer is comparable to that seen in the controls but the signal intensity appears elevated, suggesting a higher density of cells.
Specimen Stt3b +/- E10.5: embryonic day 10.5; Stt3bem1(IMPC)J/Stt3b+ (more )
Structure Cell Type Level Pattern Image Note
TS17: labyrinthine zone syncytiotrophoblast cell Present Regionally restricted Extended Data 18F +/- Tfeb , Extended Data 18E +/- Tfeb Expression is seen in SynTI cells and precursors.
Specimen Stt3b -/- E10.5: embryonic day 10.5; Stt3bem1(IMPC)J/Stt3bem1(IMPC)J (more )
Structure Cell Type Level Pattern Image Note
TS17: labyrinthine zone syncytiotrophoblast cell Present Regionally restricted Extended Data 18E -/- Tfeb , Extended Data 18F -/- Tfeb Expression is seen in SynTI cells and precursors; in the mutant the size of this layer is slightly reduced compared to that seen in the controls but the signal intensity appears elevated, suggesting a higher density of cells.
Specimen Traf7 +/- E9.5: embryonic day 9.5; Traf7em1(IMPC)Tcp/Traf7+ (more )
Structure Cell Type Level Pattern Image Note
TS15: labyrinthine zone syncytiotrophoblast cell Present Regionally restricted Extended Data 19C +/- Tfeb , Extended Data 19B +/- Tfeb Expression is seen in SynTI cells and precursors.
Specimen Traf7 -/- E9.5: embryonic day 9.5; Traf7em1(IMPC)Tcp/Traf7em1(IMPC)Tcp (more )
Structure Cell Type Level Pattern Image Note
TS15: labyrinthine zone syncytiotrophoblast cell Present Regionally restricted Extended Data 19B -/- Tfeb , Extended Data 19C -/- Tfeb Expression is seen in SynTI cells and precursors; in the mutant the size of this layer is comparable to that seen in the controls.
Specimen Exoc3l4 +/- E9.5: embryonic day 9.5; Exoc3l4em1(IMPC)J/Exoc3l4+ (more )
Structure Cell Type Level Pattern Image Note
TS15: labyrinthine zone syncytiotrophoblast cell Present Regionally restricted Extended Data 20B +/- Tfeb , Extended Data 20C +/- Tfeb Expression is seen in SynTI cells and precursors.
Specimen Exoc3l4 -/- E9.5: embryonic day 9.5; Exoc3l4em1(IMPC)J/Exoc3l4em1(IMPC)J (more )
Structure Cell Type Level Pattern Image Note
TS15: labyrinthine zone syncytiotrophoblast cell Present Regionally restricted Extended Data 20B -/- Tfeb , Extended Data 20C -/- Tfeb Expression is seen in SynTI cells and precursors; in the mutant the size of this layer is comparable to that seen in the controls.
Specimen Pgm1 +/- E9.5: embryonic day 9.5; Pgm1em1(IMPC)J/Pgm1+ (more )
Structure Cell Type Level Pattern Image Note
TS15: labyrinthine zone syncytiotrophoblast cell Present Regionally restricted Extended Data 21C +/- Tfeb , Extended Data 21B +/- Tfeb Expression is seen in SynTI cells and precursors.
Specimen Pgm1 -/- E9.5: embryonic day 9.5; Pgm1em1(IMPC)J/Pgm1em1(IMPC)J (more )
Structure Cell Type Level Pattern Image Note
TS15: labyrinthine zone syncytiotrophoblast cell Present Regionally restricted Extended Data 21C -/- Tfeb , Extended Data 21B -/- Tfeb Expression is seen in SynTI cells and precursors. In mutants this region fails to expand, remaining a thin layer.
Specimen Pgm1 +/- E10.5: embryonic day 10.5; Pgm1em1(IMPC)J/Pgm1+ (more )
Structure Cell Type Level Pattern Image Note
TS17: labyrinthine zone syncytiotrophoblast cell Present Regionally restricted Extended Data 21F +/- Tfeb , Extended Data 21E +/- Tfeb Expression is seen in SynTI cells and precursors.
Specimen Pgm1 -/- E10.5: embryonic day 10.5; Pgm1em1(IMPC)J/Pgm1em1(IMPC)J (more )
Structure Cell Type Level Pattern Image Note
TS17: labyrinthine zone syncytiotrophoblast cell Present Regionally restricted Extended Data 21E -/- Tfeb , Extended Data 21F -/- Tfeb Expression is seen in SynTI cells and precursors. In mutants this layer is markedly reduced.
Specimen Usb1 +/- E9.5: embryonic day 9.5; Usb1em1(IMPC)Bay/Usb1+ (more )
Structure Cell Type Level Pattern Image Note
TS15: labyrinthine zone syncytiotrophoblast cell Present Regionally restricted Extended Data 22B +/- Tfeb , Extended Data 22C +/- Tfeb Expression is seen in SynTI cells and precursors.
Specimen Usb1 -/- E9.5: embryonic day 9.5; Usb1em1(IMPC)Bay/Usb1em1(IMPC)Bay (more )
Structure Cell Type Level Pattern Image Note
TS15: labyrinthine zone syncytiotrophoblast cell Present Regionally restricted Extended Data 22B -/- Tfeb , Extended Data 22C -/- Tfeb Expression is seen in SynTI cells and precursors; in the mutant the size of this layer is comparable to that seen in the controls.
Specimen Tgds +/- E9.5: embryonic day 9.5; Tgdsem1(IMPC)Mbp/Tgds+ (more )
Structure Cell Type Level Pattern Image Note
TS15: labyrinthine zone syncytiotrophoblast cell Present Regionally restricted Extended Data 23C +/- Tfeb , Extended Data 23B +/- Tfeb Expression is seen in SynTI cells and precursors.
Specimen Tgds -/- E9.5: embryonic day 9.5; Tgdsem1(IMPC)Mbp/Tgdsem1(IMPC)Mbp (more )
Structure Cell Type Level Pattern Image Note
TS15: labyrinthine zone syncytiotrophoblast cell Present Regionally restricted Extended Data 23B -/- Tfeb , Extended Data 23C -/- Tfeb Expression is seen in SynTI cells and precursors; in the mutant the size of this layer is comparable to that seen in the controls.
Specimen Tgds +/- E10.5: embryonic day 10.5; Tgdsem1(IMPC)Mbp/Tgds+ (more )
Structure Cell Type Level Pattern Image Note
TS17: labyrinthine zone syncytiotrophoblast cell Present Regionally restricted Extended Data 23E +/- Tfeb , Extended Data 23F +/- Tfeb Expression is seen in SynTI cells and precursors.
Specimen Tgds -/- E10.5: embryonic day 10.5; Tgdsem1(IMPC)Mbp/Tgdsem1(IMPC)Mbp (more )
Structure Cell Type Level Pattern Image Note
TS17: labyrinthine zone syncytiotrophoblast cell Present Regionally restricted Extended Data 23E -/- Tfeb , Extended Data 23F -/- Tfeb Expression is seen in SynTI cells and precursors. In mutants this layer is reduced.
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09/15/2026
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