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Gene Expression Data
Assay Details
Assay
Reference: J:386951 Guertin TM, et al., Onset of embryonic and placental defects coincide in 19 of 22 novel mid-gestation lethal murine knockout lines. Development. 2026 May 15;153(10):dev205276
Assay type: RNA in situ
MGI Accession ID: MGI:8350479
Gene symbol: Gcm1
Gene name: glial cells missing homolog 1
Probe: Gcm1 cDNA
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 2F: embryonic day 9.5 (more )
Structure Cell Type Level Pattern Image Note
TS15: labyrinthine zone syncytiotrophoblast cell Present Regionally restricted 2F Expression is seen in a subset of trophoblasts--SynTII cells and precursors.
Specimen E8.5 - 3E/I; Ext1C/E: embryonic day 8.5 (more )
Note: Littermate control.
Structure Cell Type Level Pattern Image Note
TS13: labyrinthine zone syncytiotrophoblast cell Present Regionally restricted Extended Data 1C E8.5 , Extended Data 1E Gcm1 E8.5 , 3I , 3E E8.5 Expression is seen in SynTII cells and precursors; these cells are observed sporadically along the basal chorion.
Specimen E8.75 - 3E/I'; Ext1C/E: embryonic day 8.75 (more )
Note: Littermate control.
Structure Cell Type Level Pattern Image Note
TS13: labyrinthine zone syncytiotrophoblast cell Present Regionally restricted Extended Data 1C E8.75 , Extended Data 1E Gcm1 E8.75 , 3I' , 3E E8.75 Expression is seen in SynTII cells and precursors; signs of chorion involution and invasion of the allantois are observed at sites of expression.
Specimen E9.0 - Ext1C/E: embryonic day 9.0 (more )
Note: Littermate control.
Structure Cell Type Level Pattern Image Note
TS14: labyrinthine zone syncytiotrophoblast cell Present Regionally restricted Extended Data 1C E9.0 , Extended Data 1E Gcm1 E9.0 Expression is seen in SynTII cells and precursors.
Specimen E9.25 - 3E/I''; 6C Chp1 +/-; Ext1C/E; Ext8B/C: embryonic day 9.25; Chp1em1(IMPC)Tcp/Chp1+ (more )
Structure Cell Type Level Pattern Image Note
TS14: labyrinthine zone syncytiotrophoblast cell Present Regionally restricted Extended Data 8B +/- Gcm1 , Extended Data 1E Gcm1 E9.25 , Extended Data 8C +/- Gcm1 , Extended Data 1C E9.25 , 3I'' , 6C Chp1+/- Gcm1 , 3E E9.25 Expression is seen in a subset of SynTII cells and precursors.
Specimen E9.5 - Ext1C/E: embryonic day 9.5 (more )
Note: Littermate control.
Structure Cell Type Level Pattern Image Note
TS15: labyrinthine zone syncytiotrophoblast cell Present Regionally restricted Extended Data 1C E9.5 , Extended Data 1E Gcm1 E9.5 Expression is seen in a subset of SynTII cells and precursors.
Specimen E9.75 - 3E; 6B Got2 +/-; Ext1C/E; Ext14B/C: embryonic day 9.75; Got2em1(IMPC)Mbp/Got2+ (more )
Structure Cell Type Level Pattern Image Note
TS15: labyrinthine zone syncytiotrophoblast cell Present Regionally restricted Extended Data 1E Gcm1 E9.75 , Extended Data 1C E9.75 , 3E E9.75 , 6B Got+/- Gcm1 , Extended Data 14C +/- Gcm1 , Extended Data 14B +/- Gcm1 Expression is seen in a subset of SynTII cells and precursors.
Specimen E10.0 - Ext1C/E: embryonic day 10.0 (more )
Note: Littermate control.
Structure Cell Type Level Pattern Image Note
TS16: labyrinthine zone syncytiotrophoblast cell Present Regionally restricted Extended Data 1E Gcm1 E10.0 , Extended Data 1C E10.0 Expression is seen in a subset of SynTII cells and precursors.
Specimen E10.5 - 3E; 6F Traf7 +/-; Ext1C/E; Ext19E/F: embryonic day 10.5; Traf7em1(IMPC)Tcp/Traf7+ (more )
Structure Cell Type Level Pattern Image Note
TS17: labyrinthine zone syncytiotrophoblast cell Present Regionally restricted Extended Data 1C E10.5 , Extended Data 19E +/- Gcm1 , 6F Traf7+/- Gcm1 , 3E E10.5 , Extended Data 19F +/- Gcm1 , Extended Data 1E Gcm1 E10.5 Expression is seen in a subset of SynTII cells and precursors.
Specimen 6A Gmeb2 +/-; Ext11B/C: embryonic day 9.5; Gmeb2em1(IMPC)J/Gmeb2+ (more )
Structure Cell Type Level Pattern Image Note
TS15: labyrinthine zone syncytiotrophoblast cell Present Regionally restricted 6A Gmemb2+/- Gcm1 , Extended Data 11C +/- Gcm1 , Extended Data 11B +/- Gcm1 Expression is seen in a subset of SynTII cells and precursors.
Specimen 6A Gmeb2 -/-; Ext11B/C: embryonic day 9.5; Gmeb2em1(IMPC)J/Gmeb2em1(IMPC)J (more )
Structure Cell Type Level Pattern Image Note
TS15: labyrinthine zone syncytiotrophoblast cell Present Regionally restricted Extended Data 11C -/- Gcm1 , Extended Data 11B -/- Gcm1 , 6A Gmemb2-/- Gcm1 Expression is seen in a subset of SynTII cells and precursors; in the mutant a mild chorioallantoic branching defect was observed.
Specimen 6B Got2 -/-; Ext14B/C: embryonic day 9.5; Got2em1(IMPC)Mbp/Got2em1(IMPC)Mbp (more )
Structure Cell Type Level Pattern Image Note
TS15: labyrinthine zone syncytiotrophoblast cell Present Regionally restricted Extended Data 14B -/- Gcm1 , 6B Got-/- Gcm1 , Extended Data 14C -/- Gcm1 Expression is seen in a subset of SynTII cells and precursors; in the mutant a severe chorioallantoic branching defect was observed.
Specimen 6C Chp1 -/-; Ext8B/C: embryonic day 9.5; Chp1em1(IMPC)Tcp/Chp1em1(IMPC)Tcp (more )
Structure Cell Type Level Pattern Image Note
TS15: labyrinthine zone syncytiotrophoblast cell Present Regionally restricted 6C Chp1-/- Gcm1 , Extended Data 8B -/- #2 Gcm1 , Extended Data 8C -/- #2 Gcm1 Expression is seen in a subset of SynTII cells and precursors; in the mutant chorioallantoic branching and SynTII differentiation initiate but fail to further elongate and undergo secondary branching.
Specimen 6D Exoc3l4 +/-; Ext20D/E: embryonic day 10.5; Exoc3l4em1(IMPC)J/Exoc3l4+ (more )
Structure Cell Type Level Pattern Image Note
TS17: labyrinthine zone syncytiotrophoblast cell Present Regionally restricted 6D Exoc3l4+/- Gcm1 , Extended Data 20E +/- Gcm1 , Extended Data 20D +/- Gcm1 Expression is seen in a subset of SynTII cells and precursors.
Specimen 6D Exoc3l4 -/-; Ext20D/E: embryonic day 10.5; Exoc3l4em1(IMPC)J/Exoc3l4em1(IMPC)J (more )
Structure Cell Type Level Pattern Image Note
TS17: labyrinthine zone syncytiotrophoblast cell Present Regionally restricted 6D Exoc3l4-/- Gcm1 , Extended Data 20E -/- Gcm1 , Extended Data 20D -/- Gcm1 Expression is seen in a subset of SynTII cells and precursors; in the mutant chorioallantoic branching and SynTII development was severely impaired.
Specimen 6E Usb1 +/-; Ext22E/F: embryonic day 10.5; Usb1em1(IMPC)Bay/Usb1+ (more )
Structure Cell Type Level Pattern Image Note
TS17: labyrinthine zone syncytiotrophoblast cell Present Regionally restricted Extended Data 22E +/- Gcm1 , Extended Data 22F +/- Gcm1 , 6E Usb1+/- Gcm1 Expression is seen in a subset of SynTII cells and precursors.
Specimen 6E Usb1 -/-; Ext22E/F: embryonic day 10.5; Usb1em1(IMPC)Bay/Usb1em1(IMPC)Bay (more )
Structure Cell Type Level Pattern Image Note
TS17: labyrinthine zone syncytiotrophoblast cell Present Regionally restricted 6E Usb1-/- Gcm1 , Extended Data 22F -/- Gcm1 , Extended Data 22E -/- Gcm1 Expression is seen in a subset of SynTII cells and precursors; in the mutant chorioallantoic branching and SynTII development was decreased; expression is sparse and remains at the chorioallantoic interface.
Specimen 6F Traf7 -/-; Ext19E/F: embryonic day 10.5; Traf7em1(IMPC)Tcp/Traf7em1(IMPC)Tcp (more )
Structure Cell Type Level Pattern Image Note
TS17: labyrinthine zone syncytiotrophoblast cell Present Regionally restricted 6F Traf7-/- Gcm1 , Extended Data 19E -/- Gcm1 , Extended Data 19F -/- Gcm1 Expression is seen in a subset of SynTII cells and precursors; in the mutant chorioallantoic branching and SynTII development is nearly absent; expression is sparse.
Specimen Atp1b1 +/- E9.5: embryonic day 9.5; Atp1b1em1(IMPC)Mbp/Atp1b1+ (more )
Structure Cell Type Level Pattern Image Note
TS15: labyrinthine zone syncytiotrophoblast cell Present Regionally restricted Extended Data 2B +/- Gcm1 , Extended Data 2C +/- Gcm1 Expression is seen in a subset of SynTII cells and precursors.
Specimen Atp1b1 -/- E9.5: embryonic day 9.5; Atp1b1em1(IMPC)Mbp/Atp1b1em1(IMPC)Mbp (more )
Structure Cell Type Level Pattern Image Note
TS15: labyrinthine zone syncytiotrophoblast cell Present Regionally restricted Extended Data 2B -/- Gcm1 , Extended Data 2C -/- Gcm1 Expression is seen in a subset of SynTII cells and precursors; in the mutant chorioallantoic branching and SynTII development is comparable to that seen in controls.
Specimen Ehbp1 +/- E9.5: embryonic day 9.5; Ehbp1em1(IMPC)J/Ehbp1+ (more )
Structure Cell Type Level Pattern Image Note
TS15: labyrinthine zone syncytiotrophoblast cell Present Regionally restricted Extended Data 3B +/- Gcm1 , Extended Data 3C +/- Gcm1 Expression is seen in a subset of SynTII cells and precursors.
Specimen Ehbp1 -/- E9.5: embryonic day 9.5; Ehbp1em1(IMPC)J/Ehbp1em1(IMPC)J (more )
Structure Cell Type Level Pattern Image Note
TS15: labyrinthine zone syncytiotrophoblast cell Present Regionally restricted Extended Data 3B -/- Gcm1 , Extended Data 3C -/- Gcm1 Expression is seen in a subset of SynTII cells and precursors; in the mutant chorioallantoic branching and SynTII development is comparable to that seen in controls. (A slight reduction in the SynTII layer was observed but was attributed to the developmental delay of the conceptus.)
Specimen Tedc2 +/- E9.5: embryonic day 9.5; Tedc2em1(IMPC)J/Tedc2+ (more )
Structure Cell Type Level Pattern Image Note
TS15: labyrinthine zone syncytiotrophoblast cell Present Regionally restricted Extended Data 4B +/- Gcm1 , Extended Data 4C +/- Gcm1 Expression is seen in a subset of SynTII cells and precursors.
Specimen Tedc2 -/- E9.5: embryonic day 9.5; Tedc2em1(IMPC)J/Tedc2em1(IMPC)J (more )
Structure Cell Type Level Pattern Image Note
TS15: labyrinthine zone syncytiotrophoblast cell Present Regionally restricted Extended Data 4B -/- Gcm1 , Extended Data 4C -/- Gcm1 Expression is seen in a subset of SynTII cells and precursors; in the mutant chorioallantoic branching and SynTII development is comparable to that seen in controls. (A slight reduction in the SynTII layer was observed but was attributed to the developmental delay of the conceptus.)
Specimen Zmym2 +/- E9.5: embryonic day 9.5; Zmym2em1(IMPC)J/Zmym2+ (more )
Structure Cell Type Level Pattern Image Note
TS15: labyrinthine zone syncytiotrophoblast cell Present Regionally restricted Extended Data 5B +/- Gcm1 , Extended Data 5C +/- Gcm1 Expression is seen in a subset of SynTII cells and precursors.
Specimen Zmym2 -/- E9.5: embryonic day 9.5; Zmym2em1(IMPC)J/Zmym2em1(IMPC)J (more )
Structure Cell Type Level Pattern Image Note
TS15: labyrinthine zone syncytiotrophoblast cell Present Regionally restricted Extended Data 5B -/- Gcm1 , Extended Data 5C -/- Gcm1 Expression is seen in a subset of SynTII cells and precursors; in the mutant chorioallantoic branching and SynTII development is comparable to that seen in controls.
Specimen Gcn1 +/- E9.5: embryonic day 9.5; Gcn1em1(IMPC)J/Gcn1+ (more )
Structure Cell Type Level Pattern Image Note
TS15: labyrinthine zone syncytiotrophoblast cell Present Regionally restricted Extended Data 6B +/- Gcm1 , Extended Data 6C +/- Gcm1 Expression is seen in a subset of SynTII cells and precursors.
Specimen Gcn1 -/- E9.5 - #1: embryonic day 9.5; Gcn1em1(IMPC)J/Gcn1em1(IMPC)J (more )
Structure Cell Type Level Pattern Image Note
TS15: labyrinthine zone syncytiotrophoblast cell Present Regionally restricted Extended Data 6B -/- #1 Gcm1 , Extended Data 6C -/- #1 Gcm1 Expression is seen in a subset of SynTII cells and precursors; in the mutant chorioallantoic branching and SynTII differentiation initiate but fail to further elongate and undergo secondary branching.
Specimen Gcn1 -/- E9.5 - #2: embryonic day 9.5; Gcn1em1(IMPC)J/Gcn1em1(IMPC)J (more )
Structure Cell Type Level Pattern Image Note
TS15: labyrinthine zone syncytiotrophoblast cell Present Regionally restricted Extended Data 6B -/- #2 Gcm1 , Extended Data 6C -/- #2 Gcm1 Expression is seen in a subset of SynTII cells and precursors; in the mutant chorioallantoic branching and SynTII differentiation initiate but fail to further elongate and undergo secondary branching.
Specimen Slc30a9 Control E9.5: embryonic day 9.5 (more )
Note: Littermate control.
Structure Cell Type Level Pattern Image Note
TS15: labyrinthine zone syncytiotrophoblast cell Present Regionally restricted Extended Data 7C Control Gcm1 , Extended Data 7B Control Gcm1 Expression is seen in a subset of SynTII cells and precursors.
Specimen Slc30a9 -/- E9.5: embryonic day 9.5; Slc30a9em1(IMPC)Bay/Slc30a9em1(IMPC)Bay (more )
Structure Cell Type Level Pattern Image Note
TS15: labyrinthine zone syncytiotrophoblast cell Present Regionally restricted Extended Data 7C -/- Gcm1 , Extended Data 7B -/- Gcm1 Expression is seen in a subset of SynTII cells and precursors; in the mutant chorioallantoic branching and SynTII development was decreased.
Specimen Chp1 -/- E9.5 - #1: embryonic day 9.5; Chp1em1(IMPC)Tcp/Chp1em1(IMPC)Tcp (more )
Structure Cell Type Level Pattern Image Note
TS15: labyrinthine zone syncytiotrophoblast cell Present Regionally restricted Extended Data 8C -/- #1 Gcm1 , Extended Data 8B -/- #1 Gcm1 Expression is seen in a subset of SynTII cells and precursors; in the mutant chorioallantoic branching and SynTII differentiation initiate but fail to further elongate and undergo secondary branching.
Specimen Ppox +/- E9.5: embryonic day 9.5; Ppoxem1(IMPC)J/Ppox+ (more )
Structure Cell Type Level Pattern Image Note
TS15: labyrinthine zone syncytiotrophoblast cell Present Regionally restricted Extended Data 9C +/- Gcm1 , Extended Data 9B +/- Gcm1 Expression is seen in a subset of SynTII cells and precursors.
Specimen Ppox -/- E9.5: embryonic day 9.5; Ppoxem1(IMPC)J/Ppoxem1(IMPC)J (more )
Structure Cell Type Level Pattern Image Note
TS15: labyrinthine zone syncytiotrophoblast cell Present Regionally restricted Extended Data 9C -/- Gcm1 , Extended Data 9B -/- Gcm1 Expression is seen in a subset of SynTII cells and precursors; in the mutant chorioallantoic branching and SynTII differentiation initiate but fail to further elongate and undergo secondary branching.
Specimen Urm1 +/- E9.5: embryonic day 9.5; Urm1em1(IMPC)J/Urm1+ (more )
Structure Cell Type Level Pattern Image Note
TS15: labyrinthine zone syncytiotrophoblast cell Present Regionally restricted Extended Data 10B +/- Gcm1 , Extended Data 10C +/- Gcm1 Expression is seen in a subset of SynTII cells and precursors.
Specimen Urm1 -/- E9.5: embryonic day 9.5; Urm1em1(IMPC)J/Urm1em1(IMPC)J (more )
Structure Cell Type Level Pattern Image Note
TS15: labyrinthine zone syncytiotrophoblast cell Present Regionally restricted Extended Data 10C -/- Gcm1 , Extended Data 10B -/- Gcm1 Expression is seen in a subset of SynTII cells and precursors; in the mutant chorioallantoic branching and SynTII development was decreased.
Specimen Kctd5 +/- E9.5: embryonic day 9.5; Kctd5em1(IMPC)J/Kctd5+ (more )
Structure Cell Type Level Pattern Image Note
TS15: labyrinthine zone syncytiotrophoblast cell Present Regionally restricted Extended Data 12B +/- Gcm1 , Extended Data 12C +/- Gcm1 Expression is seen in a subset of SynTII cells and precursors.
Specimen Kctd5 -/- E9.5: embryonic day 9.5; Kctd5em1(IMPC)J/Kctd5em1(IMPC)J (more )
Structure Cell Type Level Pattern Image Note
TS15: labyrinthine zone syncytiotrophoblast cell Present Regionally restricted Extended Data 12C -/- Gcm1 , Extended Data 12B -/- Gcm1 Expression is seen in a subset of SynTII cells and precursors; in the mutant chorioallantoic branching and SynTII development was decreased.
Specimen Rprd2 +/- E9.5: embryonic day 9.5; Rprd2em1(IMPC)J/Rprd2+ (more )
Structure Cell Type Level Pattern Image Note
TS15: labyrinthine zone syncytiotrophoblast cell Present Regionally restricted Extended Data 13C +/- Gcm1 , Extended Data 13B +/- Gcm1 Expression is seen in a subset of SynTII cells and precursors.
Specimen Rprd2 -/- E9.5: embryonic day 9.5; Rprd2em1(IMPC)J/Rprd2em1(IMPC)J (more )
Structure Cell Type Level Pattern Image Note
TS15: labyrinthine zone syncytiotrophoblast cell Present Regionally restricted Extended Data 13C -/- Gcm1 , Extended Data 13B -/- Gcm1 Expression is seen in a subset of SynTII cells and precursors; in the mutant minimal expression indicates a complete failure of chorioallantoic branching and SynTII differentiation.
Specimen Arpc1a +/- E9.5: embryonic day 9.5; Arpc1aem1(IMPC)J/Arpc1a+ (more )
Structure Cell Type Level Pattern Image Note
TS15: labyrinthine zone syncytiotrophoblast cell Present Regionally restricted Extended Data 15B +/- Gcm1 , Extended Data 15C +/- Gcm1 Expression is seen in a subset of SynTII cells and precursors.
Specimen Arpc1a -/- E9.5: embryonic day 9.5; Arpc1aem1(IMPC)J/Arpc1aem1(IMPC)J (more )
Structure Cell Type Level Pattern Image Note
TS15: labyrinthine zone syncytiotrophoblast cell Present Regionally restricted Extended Data 15B -/- Gcm1 , Extended Data 15C -/- Gcm1 Expression is seen in a subset of SynTII cells and precursors; in the mutant chorioallantoic branching and SynTII development is comparable to that seen in controls.
Specimen Arpc1a +/- E10.5: embryonic day 10.5; Arpc1aem1(IMPC)J/Arpc1a+ (more )
Structure Cell Type Level Pattern Image Note
TS17: labyrinthine zone syncytiotrophoblast cell Present Regionally restricted Extended Data 15E +/- Gcm1 , Extended Data 15F +/- Gcm1 Expression is seen in a subset of SynTII cells and precursors.
Specimen Arpc1a -/- E10.5: embryonic day 10.5; Arpc1aem1(IMPC)J/Arpc1aem1(IMPC)J (more )
Structure Cell Type Level Pattern Image Note
TS17: labyrinthine zone syncytiotrophoblast cell Present Regionally restricted Extended Data 15E -/- Gcm1 , Extended Data 15F -/- Gcm1 Expression is seen in a subset of SynTII cells and precursors; in the mutant chorioallantoic branching and SynTII development was decreased.
Specimen Alg3 +/- E9.5: embryonic day 9.5; Alg3em1(IMPC)J/Alg3+ (more )
Structure Cell Type Level Pattern Image Note
TS15: labyrinthine zone syncytiotrophoblast cell Present Regionally restricted Extended Data 16C +/- Gcm1 , Extended Data 16B +/- Gcm1 Expression is seen in a subset of SynTII cells and precursors.
Specimen Alg3 -/- E9.5: embryonic day 9.5; Alg3em1(IMPC)J/Alg3em1(IMPC)J (more )
Structure Cell Type Level Pattern Image Note
TS15: labyrinthine zone syncytiotrophoblast cell Present Regionally restricted Extended Data 16B -/- Gcm1 , Extended Data 16C -/- Gcm1 Expression is seen in a subset of SynTII cells and precursors; in the mutant chorioallantoic branching and SynTII development was decreased.
Specimen Alg3 +/- E10.5: embryonic day 10.5; Alg3em1(IMPC)J/Alg3+ (more )
Structure Cell Type Level Pattern Image Note
TS17: labyrinthine zone syncytiotrophoblast cell Present Regionally restricted Extended Data 16E +/- Gcm1 , Extended Data 16F +/- Gcm1 Expression is seen in a subset of SynTII cells and precursors.
Specimen Alg3 -/- E10.5: embryonic day 10.5; Alg3em1(IMPC)J/Alg3em1(IMPC)J (more )
Structure Cell Type Level Pattern Image Note
TS17: labyrinthine zone syncytiotrophoblast cell Present Regionally restricted Extended Data 16E -/- Gcm1 , Extended Data 16F -/- Gcm1 Expression is seen in a subset of SynTII cells and precursors; in the mutant chorioallantoic branching and SynTII development was decreased as demonstrated by limited expression.
Specimen Bltp2 +/- E9.5: embryonic day 9.5; Bltp2em1(IMPC)J/Bltp2+ (more )
Structure Cell Type Level Pattern Image Note
TS15: labyrinthine zone syncytiotrophoblast cell Present Regionally restricted Extended Data 17C +/- Gcm1 , Extended Data 17B +/- Gcm1 Expression is seen in a subset of SynTII cells and precursors.
Specimen Bltp2 -/- E9.5: embryonic day 9.5; Bltp2em1(IMPC)J/Bltp2em1(IMPC)J (more )
Structure Cell Type Level Pattern Image Note
TS15: labyrinthine zone syncytiotrophoblast cell Present Regionally restricted Extended Data 17C -/- Gcm1 , Extended Data 17B -/- Gcm1 Expression is seen in a subset of SynTII cells and precursors; in the mutant chorioallantoic branching and SynTII development is comparable to that seen in controls.
Specimen Bltp2 +/- E10.5: embryonic day 10.5; Bltp2em1(IMPC)J/Bltp2+ (more )
Structure Cell Type Level Pattern Image Note
TS17: labyrinthine zone syncytiotrophoblast cell Present Regionally restricted Extended Data 17E +/- Gcm1 , Extended Data 17F +/- Gcm1 Expression is seen in a subset of SynTII cells and precursors.
Specimen Bltp2 -/- E10.5: embryonic day 10.5; Bltp2em1(IMPC)J/Bltp2em1(IMPC)J (more )
Structure Cell Type Level Pattern Image Note
TS17: labyrinthine zone syncytiotrophoblast cell Present Regionally restricted Extended Data 17F -/- Gcm1 , Extended Data 17E -/- Gcm1 Expression is seen in a subset of SynTII cells and precursors; in 3 mutants chorioallantoic branching and SynTII development was decreased; in the fourth mutant they developed normally.
Specimen Stt3b +/- E9.5: embryonic day 9.5; Stt3bem1(IMPC)J/Stt3b+ (more )
Structure Cell Type Level Pattern Image Note
TS15: labyrinthine zone syncytiotrophoblast cell Present Regionally restricted Extended Data 18C +/- Gcm1 , Extended Data 18B +/- Gcm1 Expression is seen in a subset of SynTII cells and precursors.
Specimen Stt3b -/- E9.5: embryonic day 9.5; Stt3bem1(IMPC)J/Stt3bem1(IMPC)J (more )
Structure Cell Type Level Pattern Image Note
TS15: labyrinthine zone syncytiotrophoblast cell Present Regionally restricted Extended Data 18C -/- Gcm1 , Extended Data 18B -/- Gcm1 Expression is seen in a subset of SynTII cells and precursors; in the mutant chorioallantoic branching and SynTII development was decreased.
Specimen Stt3b +/- E10.5: embryonic day 10.5; Stt3bem1(IMPC)J/Stt3b+ (more )
Structure Cell Type Level Pattern Image Note
TS17: labyrinthine zone syncytiotrophoblast cell Present Regionally restricted Extended Data 18F +/- Gcm1 , Extended Data 18E +/- Gcm1 Expression is seen in a subset of SynTII cells and precursors.
Specimen Stt3b -/- E10.5: embryonic day 10.5; Stt3bem1(IMPC)J/Stt3bem1(IMPC)J (more )
Structure Cell Type Level Pattern Image Note
TS17: labyrinthine zone syncytiotrophoblast cell Present Regionally restricted Extended Data 18E -/- Gcm1 , Extended Data 18F -/- Gcm1 Expression is seen in a subset of SynTII cells and precursors; in the mutant chorioallantoic branching and SynTII development was decreased.
Specimen Traf7 +/- E9.5: embryonic day 9.5; Traf7em1(IMPC)Tcp/Traf7+ (more )
Structure Cell Type Level Pattern Image Note
TS15: labyrinthine zone syncytiotrophoblast cell Present Regionally restricted Extended Data 19B +/- Gcm1 , Extended Data 19C +/- Gcm1 Expression is seen in a subset of SynTII cells and precursors.
Specimen Traf7 -/- E9.5: embryonic day 9.5; Traf7em1(IMPC)Tcp/Traf7em1(IMPC)Tcp (more )
Structure Cell Type Level Pattern Image Note
TS15: labyrinthine zone syncytiotrophoblast cell Present Regionally restricted Extended Data 19B -/- Gcm1 , Extended Data 19C -/- Gcm1 Expression is seen in a subset of SynTII cells and precursors; in the mutant chorioallantoic branching and SynTII development is comparable to that seen in controls.
Specimen Exoc3l4 +/- E9.5: embryonic day 9.5; Exoc3l4em1(IMPC)J/Exoc3l4+ (more )
Structure Cell Type Level Pattern Image Note
TS15: labyrinthine zone syncytiotrophoblast cell Present Regionally restricted Extended Data 20C +/- Gcm1 , Extended Data 20B +/- Gcm1 Expression is seen in a subset of SynTII cells and precursors.
Specimen Exoc3l4 -/- E9.5: embryonic day 9.5; Exoc3l4em1(IMPC)J/Exoc3l4em1(IMPC)J (more )
Structure Cell Type Level Pattern Image Note
TS15: labyrinthine zone syncytiotrophoblast cell Present Regionally restricted Extended Data 20B -/- Gcm1 , Extended Data 20C -/- Gcm1 Expression is seen in a subset of SynTII cells and precursors; in the mutant chorioallantoic branching and SynTII development is comparable to that seen in controls.
Specimen Pgm1 +/- E9.5: embryonic day 9.5; Pgm1em1(IMPC)J/Pgm1+ (more )
Structure Cell Type Level Pattern Image Note
TS15: labyrinthine zone syncytiotrophoblast cell Present Regionally restricted Extended Data 21C +/- Gcm1 , Extended Data 21B +/- Gcm1 Expression is seen in a subset of SynTII cells and precursors.
Specimen Pgm1 -/- E9.5: embryonic day 9.5; Pgm1em1(IMPC)J/Pgm1em1(IMPC)J (more )
Structure Cell Type Level Pattern Image Note
TS15: labyrinthine zone syncytiotrophoblast cell Present Regionally restricted Extended Data 21B -/- Gcm1 , Extended Data 21C -/- Gcm1 Expression is seen in a subset of SynTII cells and precursors; in the mutant chorioallantoic branching and SynTII development was decreased.
Specimen Pgm1 +/- E10.5: embryonic day 10.5; Pgm1em1(IMPC)J/Pgm1+ (more )
Structure Cell Type Level Pattern Image Note
TS17: labyrinthine zone syncytiotrophoblast cell Present Regionally restricted Extended Data 21F +/- Gcm1 , Extended Data 21E +/- Gcm1 Expression is seen in a subset of SynTII cells and precursors.
Specimen Pgm1 -/- E10.5: embryonic day 10.5; Pgm1em1(IMPC)J/Pgm1em1(IMPC)J (more )
Structure Cell Type Level Pattern Image Note
TS17: labyrinthine zone syncytiotrophoblast cell Present Regionally restricted Extended Data 21F -/- Gcm1 , Extended Data 21E -/- Gcm1 Expression is seen in a subset of SynTII cells and precursors; in mutants expression is sparse as chorioallantoic branching and SynTII layer formation is nearly absent.
Specimen Usb1 +/- E9.5: embryonic day 9.5; Usb1em1(IMPC)Bay/Usb1+ (more )
Structure Cell Type Level Pattern Image Note
TS15: labyrinthine zone syncytiotrophoblast cell Present Regionally restricted Extended Data 22B +/- Gcm1 , Extended Data 22C +/- Gcm1 Expression is seen in a subset of SynTII cells and precursors.
Specimen Usb1 -/- E9.5: embryonic day 9.5; Usb1em1(IMPC)Bay/Usb1em1(IMPC)Bay (more )
Structure Cell Type Level Pattern Image Note
TS15: labyrinthine zone syncytiotrophoblast cell Present Regionally restricted Extended Data 22B -/- Gcm1 , Extended Data 22C -/- Gcm1 Expression is seen in a subset of SynTII cells and precursors; in the mutant chorioallantoic branching and SynTII development is comparable to that seen in controls.
Specimen Tgds +/- E9.5: embryonic day 9.5; Tgdsem1(IMPC)Mbp/Tgds+ (more )
Structure Cell Type Level Pattern Image Note
TS15: labyrinthine zone syncytiotrophoblast cell Present Regionally restricted Extended Data 23B +/- Gcm1 , Extended Data 23C +/- Gcm1 Expression is seen in a subset of SynTII cells and precursors.
Specimen Tgds -/- E9.5: embryonic day 9.5; Tgdsem1(IMPC)Mbp/Tgdsem1(IMPC)Mbp (more )
Structure Cell Type Level Pattern Image Note
TS15: labyrinthine zone syncytiotrophoblast cell Present Regionally restricted Extended Data 23C -/- Gcm1 , Extended Data 23B -/- Gcm1 Expression is seen in a subset of SynTII cells and precursors; in the mutant chorioallantoic branching and SynTII development is comparable to that seen in controls.
Specimen Tgds +/- E10.5: embryonic day 10.5; Tgdsem1(IMPC)Mbp/Tgds+ (more )
Structure Cell Type Level Pattern Image Note
TS17: labyrinthine zone syncytiotrophoblast cell Present Regionally restricted Extended Data 23E +/- Gcm1 , Extended Data 23F +/- Gcm1 Expression is seen in a subset of SynTII cells and precursors.
Specimen Tgds -/- E10.5: embryonic day 10.5; Tgdsem1(IMPC)Mbp/Tgdsem1(IMPC)Mbp (more )
Structure Cell Type Level Pattern Image Note
TS17: labyrinthine zone syncytiotrophoblast cell Present Regionally restricted Extended Data 23F -/- Gcm1 , Extended Data 23E -/- Gcm1 Expression is seen in a subset of SynTII cells and precursors; in mutants expression is sparse as chorioallantoic branching and SynTII layer formation is nearly absent.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/15/2026
MGI 6.29 		The Jackson Laboratory