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Human Disease and Mouse Model Detail
Human Disease Diabetes Mellitus, Insulin-Dependent; IDDM
OMIM ID: 222100
Human Phenotype Ontology associations
Synonyms Diabetes Mellitus, Insulin-Dependent; Diabetes Mellitus, Type I
View all models View ALL (78) mouse models for this human disease.
Genes and
mouse models
Mutations in human and/or mouse homologs are associated with this disease

      *Disease is associated/modeled with this Gene or a homolog. More...
      Human Homologs Mouse Homologs Mouse Models Homology Source
     CD38 Cd38* View 1 model HomoloGene and HGNC
CDK4 Cdk4* View 1 model HomoloGene
E2F1 E2f1* View 1 model HomoloGene
FASLG Fasl* View 3 models HomoloGene
G6PC2 G6pc2* View 1 model HomoloGene
GAD2 Gad2* View 1 model HomoloGene
IFNG Ifng* View 2 models HomoloGene and HGNC
IFNGR2 Ifngr2* View 1 model HomoloGene
Ighg* View 1 model
Ighm* View 5 models
IL1R1 Il1r1* View 1 model HomoloGene
IL4 Il4* View 2 models HomoloGene and HGNC
INS Ins2* View 7 models HomoloGene
NOS2 Nos2* View 5 models HomoloGene and HGNC
PDX1 Pdx1* View 1 model HomoloGene and HGNC
PRF1 Prf1* View 2 models HomoloGene
PTPRN2 Ptprn2* View 1 model HomoloGene
SELL Sell* View 4 models HomoloGene
SENP1 Senp1* View 1 model HomoloGene and HGNC
STAT4 Stat4* View 4 models HomoloGene and HGNC
TNFSF4 Tnfsf4* View 1 model HomoloGene
     FOXP3* Foxp3   HomoloGene and HGNC
HNF1A* Hnf1a   HomoloGene
ITPR3* Itpr3   HomoloGene
OAS1* Oas1a, Oas1b, Oas1c, Oas1d, Oas1e, Oas1f, Oas1g, Oas1h   HGNC
PTPN22* Ptpn22   HomoloGene
Transgenes and
other genome features
Transgenes and other genome features developed in mice to model this disease.

     Transgenes and Other Genome Features Mouse Models
  H2-I View 1 model
  Tcra View 13 models
  Tg(H2-Ea-G6pc2)69Tkay View 1 model
  Tg(H2-Ea-Ins2)1Wehi View 1 model
  Tg(H2-Ead)12Lt View 1 model
  Tg(HLA-A/H2-D/B2M)1Dvs View 2 models
  Tg(Igh-6/Igh-V281)3Jwt View 2 models
  Tg(Igh-VB1-8/Igh-6m)1Mjsk View 1 model
  Tg(IghelMD4)4Ccg View 1 model
  Tg(Ins1-Cat,Tyr)25Pne View 2 models
  Tg(Ins2*Y16A)3Ell View 1 model
  Tg(Ins2-CALM1)26Ove View 2 models
  Tg(Ins2-CD80)3B7Flv View 4 models
  Tg(Ins2-CD86)12B70Flv View 1 model
  Tg(Ins2-Fasl)24Ach View 3 models
  Tg(Ins2-GP)34-20Olds View 2 models
  Tg(Ins2-HBEGF)5Rin View 1 model
  Tg(Ins2-Nos2)31Okam View 1 model
  Tg(Ins2-Nos2)40Okam View 4 models
  Tg(Ins2-NP)25-3Olds View 2 models
  Tg(INS-MT2A,Tyr)1Pne View 2 models
  Tg(INS-SOD2)3Pne View 1 model
  Tg(TcraAI4)1Dvs View 5 models
  Tg(TcraTcrbNY8.3)1Pesa View 1 model
References Disease References using Mouse Models (79)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.05
The Jackson Laboratory