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Human Disease and Mouse Model Detail
Human Disease Breast Cancer
OMIM ID: 114480
Synonyms Breast Cancer
View all models View ALL (72) mouse models for this human disease.
Genes and
mouse models
Mutations in human and/or mouse homologs are associated with this disease

      *Disease is associated/modeled with this Gene or a homolog. More...
      Human Homologs Mouse Homologs Mouse Models Homology Source
     BARD1* Bard1* View 3 models HomoloGene and HGNC
BRCA1* Brca1* View 11 models HomoloGene and HGNC
BRCA2* Brca2* View 6 models HomoloGene
ESR1* Esr1* View 1 model HomoloGene
PIK3CA* Pik3ca* View 4 models HomoloGene
TP53* Trp53* View 11 models HomoloGene and HGNC
     APC Apc* View 2 models HomoloGene and HGNC
CAV1 Cav1* View 1 model HomoloGene and HGNC
ERBB2 Erbb2* View 14 models HomoloGene and HGNC
ESPL1 Espl1* View 1 model HomoloGene
HGF Hgf* View 2 models HomoloGene and HGNC
MET Met* View 1 model HomoloGene
MYC Myc* View 7 models HomoloGene
WNT1 Wnt1* View 2 models HomoloGene
     AKT1* Akt1   HomoloGene and HGNC
ATM* Atm   HomoloGene
BRIP1* Brip1   HomoloGene and HGNC
CASP8* Casp8   HomoloGene and HGNC
CDH1* Cdh1   HomoloGene and HGNC
CHEK2* Chek2   HomoloGene and HGNC
HMMR* Hmmr   HomoloGene and HGNC
KRAS* Kras View 1 model HomoloGene and HGNC
NQO2* Nqo2   HomoloGene and HGNC
PALB2* Palb2   HomoloGene and HGNC
PHB* Phb   HomoloGene
PPM1D* Ppm1d   HomoloGene and HGNC
RAD51* Rad51   HomoloGene and HGNC
RAD54L* Rad54l   HomoloGene
RB1CC1* Rb1cc1   HomoloGene and HGNC
SLC22A18* Slc22a18   HomoloGene and HGNC
TSG101* Tsg101   HomoloGene
XRCC3* Xrcc3   HomoloGene
Transgenes and
other genome features
Transgenes and other genome features developed in mice to model this disease.

     Transgenes and Other Genome Features Mouse Models
  T(9;17)138Ca View 1 model
  Tg(C3-1-TAg)cJeg View 1 model
  Tg(MMTV-AURKA)#Cxd View 2 models
  Tg(MMTV-ERBB2)5Erick View 1 model
  Tg(MMTV-Erbb2)9Pjo View 1 model
  Tg(MMTV-Erbb2)10Pjo View 1 model
  Tg(MMTV-Erbb2)12Pjo View 1 model
  Tg(MMTV-Erbb2)17Pjo View 1 model
  Tg(MMTV-Erbb2)NK1Mul View 1 model
  Tg(MMTV-Erbb2*,-cre)1Mul View 1 model
  Tg(MMTV-ERBB2*,-luc)6157Aami View 1 model
  Tg(MMTV-Espl1)1Pati View 1 model
  Tg(MMTV-Myc)WT13Jrn View 1 model
  Tg(MMTV-Myc)WT21Jrn View 1 model
  Tg(MMTV-Myc*T58A)TA14Jrn View 1 model
  Tg(MMTV-Myc*T58A)TA39Jrn View 1 model
  Tg(MMTV-Myc*T58A)TA41Jrn View 1 model
  Tg(MMTV-neu/OT-I/OT-II)CBnel View 2 models
  Tg(MMTV-PyVT)634Mul View 1 model
  Tg(MMTV-PyVT)#Mul View 1 model
  Tg(MMTV-PyVT*Y250F)250-2Mul View 1 model
  Tg(MMTV-PyVT*Y315F*Y322F)Db-1Mul View 1 model
  Tg(MMTV-TGFBR2)7Hlm View 1 model
  Tg(MMTVneu)202Mul View 4 models
  Tg(TetO-Erbb2)1Lach View 1 model
  Tg(tetO-Esr1)#Paf View 1 model
  Tg(tetO-IGF1R)1Ramo View 1 model
  Tg(tetO-MYC)1Lach View 1 model
  Tg(tetO-PIK3CA*H1047R,-luc)2239Jjz View 1 model
  Tg(Trp53R172H)8512Jmr View 2 models
  Tg(Wap-Hgf)402Mig View 2 models
  Tg(Wap-TAg)1Depp View 1 model
  Tg(Wap-TAg)NP8Depp View 1 model
  Tg(Wnt1)1Hev View 2 models
References Disease References using Mouse Models (84)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/25/2015
MGI 6.0
The Jackson Laboratory