Phenotypes Associated with This Genotype

Genotype
MGI:3043322

• Allelic Composition: Etv4^tm1Hass/Etv4^tm1Hass; Tg(MMTVneu)202Mul/Tg(MMTVneu)202Mul
• Genetic Background: involves: FVB/N

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

neoplasm

increased mammary gland tumor incidence ( J:87017 )

• the onset, incidence and size of primary mammary tumors were comparable to those of Tg(MMTVneu)202Mul transgenic mice

decreased metastatic potential ( J:87017 )

• unlike mammary tumors of Tg(MMTVneu)202Mul transgenic mice, mammary tumors of mice expressing Tg(MMTVneu)202Mul in a homozygous null background did not metastasize to the lung

integument

increased mammary gland tumor incidence ( J:87017 )

• the onset, incidence and size of primary mammary tumors were comparable to those of Tg(MMTVneu)202Mul transgenic mice

endocrine/exocrine glands

increased mammary gland tumor incidence ( J:87017 )

• the onset, incidence and size of primary mammary tumors were comparable to those of Tg(MMTVneu)202Mul transgenic mice

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
breast cancer		DOID:1612	OMIM:114480	J:87017