Tg(tetO-PyVT,-cre)1Mul
Transgene Detail

Summary

• Symbol: Tg(tetO-PyVT,-cre)1Mul
• Name: transgene insertion 1, William Muller
• MGI ID: MGI:5805223
• Synonyms: MIC, TetO-Pyv mT-IRES-Cre
• Transgene: Tg(tetO-PyVT,-cre)1Mul Location: unknown
• Alliance: Tg(tetO-PyVT,-cre)1Mul page

Transgene origin

• Strain of Origin: FVB/N

Transgene description

• Transgene Type: Transgenic (Inducible, Recombinase)
• Inducer: doxycycline/tetracycline
• Mutation: Insertion
• Tg(tetO-PyVT,-cre)1Mul expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  bacteria	tetO

• Mutation details: A transgene was generated where an activated PyVT (Polyomavirus middle T antigen) and cre recombinase (coupled by an internal ribosomal entry site (IRES)) are under control of the tet-responsive promoter (tetO). (J:231983)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	tetO (bacteria) Summary of all recombinase alleles driven by tetO.

Disease models

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:231983 Rao T, et al., Inducible and coupled expression of the polyomavirus middle T antigen and Cre recombinase in transgenic mice: an in vivo model for synthetic viability in mammary tumour progression. Breast Cancer Res. 2014;16(1):R11
• All: 6 reference(s)