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All mouse models of hepatobiliary disease with phenotypic similarity to the human disease
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| Disease Term | Allelic Composition | Genetic Background | Reference | Phenotypes | ||||
  | Alagille syndrome | \Jag1Mhdahtu/\Jag1+ | C3HeB/FeJ-Jag1Mhdahtu | J:72108 | View | |||
| Alagille syndrome | \Jag1Ndr/\Jag1Ndr | involves: C3HeB/FeJ * C57BL/6 | J:277897 | View | ||||
| Alagille syndrome |
\Jag1tm1Frad/\Jag1tm1Frad \Tg(Cdh5-cre)7Mlia/0 |
B6.Cg-Jag1tm1Frad Tg(Cdh5-cre)7Mlia | J:189213 | View | ||||
| Alagille syndrome |
\Jag1tm1Frad/\Jag1tm1Frad \Tg(Tagln-cre)1Her/0 |
B6.Cg-Jag1tm1Frad Tg(Tagln-cre)1Her | J:166890 | View | ||||
| Alagille syndrome |
\Jag1tm1Grid/\Jag1+ \Notch2tm1Grid/\Notch2+ |
involves: 129S1/Sv * C57BL/6J | J:74574 | View | ||||
| Alagille syndrome |
\Jag1tm2Grid/\Jag1tm2Grid \H2az2Tg(Wnt1-cre)11Rth/\H2az2+ |
involves: 129S1/Sv * C57BL/6 * CBA | J:181120 | View | ||||
| cholestasis | \Abcb4tm1Bor/\Abcb4tm1Bor | C.129P2-Abcb4tm1Bor | J:199949 | View | ||||
| hepatocellular carcinoma | \Apctm2.1Cip/\Apctm2.1Cip | involves: 129P2/OlaHsd * C57BL/6N | J:94721 | View | ||||
| hepatocellular carcinoma | \Nr1h4tm1Gonz/\Nr1h4tm1Gonz | involves: 129X1/SvJ * C57BL/6 | J:118204, J:170790 | View | ||||
| hepatocellular carcinoma | \Nr1h4tm1Gonz/\Nr1h4tm1Gonz | involves: 129X1/SvJ * C57BL/6N | J:121075, J:170790 | View | ||||
| intrahepatic cholangiocarcinoma |
\Krastm4Tyj/\Kras+ \Ptentm2Mak/\Ptentm2Mak \Speer6-ps1Tg(Alb-cre)21Mgn/\Speer6-ps1+ |
involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6 * DBA | J:254370 | View | ||||
| intrahepatic cholangiocarcinoma |
\Krastm4Tyj/\Kras+ \Speer6-ps1Tg(Alb-cre)21Mgn/\Speer6-ps1+ |
involves: 129S4/SvJae * C57BL/6 * DBA | J:184949 | View | ||||
| intrahepatic cholangiocarcinoma |
\Krastm4Tyj/\Kras+ \Trp53tm1Brn/\Trp53+ \Speer6-ps1Tg(Alb-cre)21Mgn/\Speer6-ps1+ |
involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6 * DBA | J:184949 | View | ||||
| intrahepatic cholangiocarcinoma |
\Krastm4Tyj/\Kras+ \Trp53tm1Brn/\Trp53tm1Brn \Speer6-ps1Tg(Alb-cre)21Mgn/\Speer6-ps1+ |
involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6 * DBA | J:184949 | View | ||||
| intrahepatic cholestasis | \Abcb4tm1Bor/\Abcb4tm1Bor | involves: 129P2/OlaHsd * FVB/N | J:175015 | View | ||||
| intrahepatic cholestasis |
\Abcb4tm1Bor/\Abcb4tm1Bor \Portm1Wolf/\Portm1Wolf \Speer6-ps1Tg(Alb-cre)21Mgn/\Speer6-ps1+ |
involves: 129P2/OlaHsd * C57BL/6 * DBA * FVB/N | J:215915 | View | ||||
| metabolic dysfunction-associated steatotic liver disease | \Leprdb/\Leprdb | B6.BKS(D)-Leprdb/JOrlRj | J:277927 | View | ||||
| metabolic dysfunction-associated steatotic liver disease | \Pnpla3tm2.1Hobb/\Pnpla3tm2.1Hobb | involves: 129 * C57BL/6J | J:264475 | View | ||||
| | biliary atresia | \Sox17tm1Ysk/\Sox17+ | B6.129S1-Sox17tm1Ysk | J:194071, J:241569 | View | |||
| Caroli syndrome | \Pkhd1cyli/\Pkhd1cyli | D2.Cg-(D4Mit42-D4Smh6b) Pkhd1cyli/EiJ | J:343537 | View | ||||
| cholecystitis | \Abcb4tm1Bor/\Abcb4tm1Bor | FVB.129P2-Abcb4tm1Bor/J | J:105357 | View | ||||
| hepatitis | \Tg(APCS-Ifng)5Imeg/0 | involves: C57BL/6 * DBA/2 | J:16979 | View | ||||
| hepatocellular adenoma |
\Ptpn11tm1Gsf/\Ptpn11tm1Gsf \Speer6-ps1Tg(Alb-cre)21Mgn/\Speer6-ps1+ |
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA | J:172422 | View | ||||
| hepatocellular carcinoma | \Abcb4tm1Bor/\Abcb4tm1Bor | either: (involves: 129P2/OlaHsd) or (involves: 129P2/OlaHsd * FVB/N) | J:21232 | View | ||||
| hepatocellular carcinoma | \Cdkn1atm1(HBsAg)Xya/\Cdkn1a+ | either: (involves: 129S6/SvEvTac * C57BL/6) or (involves: 129S6/SvEvTac * Black Swiss) | J:88078 | View | ||||
| hepatocellular carcinoma | \Cdkn1atm1(HBsAg)Xya/\Cdkn1atm1(HBsAg)Xya | either: (involves: 129S6/SvEvTac * C57BL/6) or (involves: 129S6/SvEvTac * Black Swiss) | J:88078 | View | ||||
| hepatocellular carcinoma | \Cdkn1atm2(HBx)Xya/\Cdkn1a+ | either: (involves: 129S6/SvEvTac * C57BL/6) or (involves: 129S6/SvEvTac * Black Swiss) | J:88078 | View | ||||
| hepatocellular carcinoma | \Cdkn1atm2(HBx)Xya/\Cdkn1atm2(HBx)Xya | either: (involves: 129S6/SvEvTac * C57BL/6) or (involves: 129S6/SvEvTac * Black Swiss) | J:88078 | View | ||||
| hepatocellular carcinoma | \Foxm1tm1Rhc/\Foxm1tm1Rhc | involves: 129X1/SvJ | J:89472 | View | ||||
| hepatocellular carcinoma | \Gnmttm1Ymac/\Gnmttm1Ymac | involves: 129 * C57BL/6 | J:146081 | View | ||||
| hepatocellular carcinoma |
\Gtf2ird1Tg(Alb1-Myc)166.8Sst/\Gtf2ird1+ \Tg(Alb-E2F1)8Sst/0 |
involves: C57BL/6 * CBA | J:101128, J:170790 | View | ||||
| hepatocellular carcinoma |
\Gtf2ird1Tg(Alb1-Myc)166.8Sst/\Gtf2ird1+ \Tg(MtTGFA)42Lmb/0 |
involves: C57BL/6 * CBA * CD-1 | J:34434 | View | ||||
| hepatocellular carcinoma | \Iqgap2tm1Vs/\Iqgap2tm1Vs | involves: 129S4/SvJae | J:205882 | View | ||||
| hepatocellular carcinoma | \Krt18tm1Tmm/\Krt18tm1Tmm | involves: 129P2/OlaHsd | J:309021 | View | ||||
| hepatocellular carcinoma |
\Lect2tm1Ymg/\Lect2tm1Ymg \Tg(Pklr-Myc)73Ak/0 |
B6.Cg-Lect2tm1Ymg Tg(Pklr-Myc)73Ak | J:184496 | View | ||||
| hepatocellular carcinoma | \Mcm9Gt(AW0655)Wtsi/\Mcm9Gt(AW0655)Wtsi | involves: 129P2/OlaHsd * C3HeB/FeJ | J:177420 | View | ||||
| hepatocellular carcinoma | \Mcm9Gt(AW0655)Wtsi/\Mcm9Gt(XG743)Byg | involves: 129P2/OlaHsd * C3HeB/FeJ | J:177420 | View | ||||
| hepatocellular carcinoma | \Mcm9Gt(XG743)Byg/\Mcm9Gt(XG743)Byg | involves: 129P2/OlaHsd * C3HeB/FeJ | J:177420 | View | ||||
| hepatocellular carcinoma |
\Nfe2l1tm1Jefc/\Nfe2l1tm1Ywk \Speer6-ps1Tg(Alb-cre)21Mgn/\Speer6-ps1+ |
involves: 129X1/SvJ * C57BL/6J | J:97188 | View | ||||
| hepatocellular carcinoma |
\Ptentm1Hwu/\Ptentm1Hwu \Speer6-ps1Tg(Alb-cre)21Mgn/\Speer6-ps1+ |
involves: 129S4/SvJae * C57BL/6 * DBA | J:218587 | View | ||||
| hepatocellular carcinoma |
\Ptentm2Mak/\Ptentm2Mak \Speer6-ps1Tg(Alb-cre)21Mgn/\Speer6-ps1+ |
involves: 129P2/OlaHsd * C57BL/6 * C57BL/6J * DBA | J:90905 | View | ||||
| hepatocellular carcinoma |
\Ptentm2Mak/\Ptentm2Mak \Speer6-ps1Tg(Alb-cre)21Mgn/\Speer6-ps1+ |
involves: 129P2/OlaHsd * C57BL/6 * DBA | J:138099 | View | ||||
| hepatocellular carcinoma |
\Sav1tm2.1Dlim/\Sav1tm2.1Dlim \Speer6-ps1Tg(Alb-cre)21Mgn/\Speer6-ps1+ |
involves: C57BL/6 * DBA | J:238319 | View | ||||
| hepatocellular carcinoma |
\Tcra-Jtm1Tgi/\Tcra-Jtm1Tgi \Tg(Pklr-Myc)73Ak/0 |
B6.Cg-Tcra-Jtm1Tgi Tg(Pklr-Myc)73Ak | J:184496 | View | ||||
| hepatocellular carcinoma |
\Tg(Alb1-Myc)#Sst/0 \Tg(MtTGFA)Lmb/0 |
involves: C57BL/6 * CBA * CD-1 | J:176432 | View | ||||
| hepatocellular carcinoma | \Tg(HBVX*,-Myc)#Skp/\Tg(HBVX*,-Myc)#Skp | Not Specified | J:81098, J:202732 | View | ||||
| hepatocellular carcinoma | \Tg(Mup3-Plau)350-2Eps/? | C57BL/6-Tg(Mup3-Plau)350-2Eps | J:233146 | View | ||||
| hepatocellular carcinoma | \Tg(Pklr-Myc)73Ak/0 | B6.Cg-Tg(Pklr-Myc)73Ak | J:184496 | View | ||||
| hepatocellular carcinoma | \Tg(Pklr-Myc)73Ak/0 | involves: C57BL/6 * DBA | J:185488 | View | ||||
| hepatocellular carcinoma | \TxnipHyplip1/\Txnip+ | involves: CAST/Ei * HcB19/Dem | J:112292 | View | ||||
| hepatocellular carcinoma | \TxnipHyplip1/\TxnipHyplip1 | HcB19/Dem-TxnipHyplip1 | J:112292 | View | ||||
| hepatocellular carcinoma | \TxnipHyplip1/\TxnipHyplip1 | involves: CAST/Ei * HcB19/Dem | J:112292 | View | ||||
| hepatocellular carcinoma | \Uacatm1Kiy/\Uacatm1Kiy | B6.129P2-Uacatm1Kiy | J:157049 | View | ||||
| liver disease |
\Speer6-ps1Tg(Alb-cre)21Mgn/\Speer6-ps1+ \Trmutm1Tomik/\Trmutm1Tomik |
involves: C57BL/6 * DBA | J:235644 | View | ||||
| liver disease |
\Ssu72tm1Cwl/\Ssu72tm1Cwl \Speer6-ps1Tg(Alb-cre)21Mgn/\Speer6-ps1+ |
B6.Cg-Ssu72tm1Cwl Speer6-ps1Tg(Alb-cre)21Mgn | J:309624 | View | ||||
| metabolic dysfunction-associated steatohepatitis | \Krt18tm1Tmm/\Krt18tm1Tmm | involves: 129P2/OlaHsd | J:309021 | View | ||||
| metabolic dysfunction-associated steatohepatitis | \Mc4rtm1Matsu/\Mc4rtm1Matsu | C57BL/6J-Mc4rtm1Matsu | J:285412 | View | ||||
| metabolic dysfunction-associated steatohepatitis | \Nwd1em2.1Sisa/\Nwd1em2.1Sisa | involves: C57BL/6 * C57BL/6N * DBA/2 | J:363603 | View | ||||
| metabolic dysfunction-associated steatotic liver disease | \Aldh1l2tm2e(KOMP)Wtsi/\Aldh1l2tm2e(KOMP)Wtsi | involves: C57BL/6 * C57BL/6N | J:299012 | View | ||||
| metabolic dysfunction-associated steatotic liver disease | \Iigp1cem1Btlr/\Iigp1cem1Btlr | C57BL/6J-Iigp1cem1Btlr | J:333470 | View | ||||
| metabolic dysfunction-associated steatotic liver disease | \Iigp1cM1Btlr/\Iigp1cM1Btlr | C57BL/6J-Iigp1cM1Btlr | J:333470 | View | ||||
| metabolic dysfunction-associated steatotic liver disease | \Iigp1cM2Btlr/\Iigp1cM2Btlr | C57BL/6J-Iigp1cM2Btlr | J:333470 | View | ||||
| metabolic dysfunction-associated steatotic liver disease | \Lepob/\Lepob | B6.Cg-Lepob/JRj | J:277927 | View | ||||
| metabolic dysfunction-associated steatotic liver disease | \Nlrp3tm1Bhk/\Nlrp3tm1Bhk | B6.129S6-Nlrp3tm1Bhk/J | J:256504 | View | ||||
| metabolic dysfunction-associated steatotic liver disease | \Pgrmc1em1Ejho/\Pgrmc1em1Ejho | involves: C57BL/6N | J:268130 | View | ||||
| metabolic dysfunction-associated steatotic liver disease |
\Ppdpftm1Nju/\Ppdpftm1Nju \Speer6-ps1Tg(Alb-cre)21Mgn/\Speer6-ps1+ |
involves: C57BL/6 * DBA | J:307283 | View | ||||
| metabolic dysfunction-associated steatotic liver disease | \Sidt2tm1.1Hzha/\Sidt2tm1.1Hzha | involves: 129S6/SvEvTac * C57BL/6J | J:236042 | View | ||||
| polycystic liver disease |
\Prkcshtm1Som/\Prkcshtm1Som \Tg(CAG-cre/Esr1*)1Lbe/0 |
involves: 129 * 129S1/Sv * 129X1/SvJ * C57BL/6 | J:188763 | View | ||||
| polycystic liver disease | \Ucp2tm1Lowl/\Ucp2tm1Lowl | B6.129S4-Ucp2tm1Lowl | J:272325 | View | ||||
| primary biliary cholangitis | \Map3k14aly/\Map3k14aly | involves: C57BL/6J | J:48224 | View | ||||
| primary biliary cholangitis |
\Zc3h12atm1c(EUCOMM)Hmgu/\Zc3h12atm1c(EUCOMM)Hmgu \Speer6-ps1Tg(Alb-cre)21Mgn/\Speer6-ps1+ |
involves: C57BL/6 * C57BL/6N * DBA | J:304105 | View | ||||
| primary sclerosing cholangitis | \Abcb4tm1Bor/\Abcb4tm1Bor | CAnNCrl.12P2(FVB)-Abcb4tm1Bor | J:217802 | View | ||||
| primary sclerosing cholangitis | \Abcb4tm1Bor/\Abcb4tm1Bor | involves: 129P2/OlaHsd * BALB/c | J:168123 | View | ||||
| steatotic liver disease | \Adktm1Bois/\Adktm1Bois | involves: 129P3/JEmsJ * C57BL/6 | J:81518 | View | ||||
| steatotic liver disease |
\Ikbkgtm1.1Mpa/\Ikbkgtm1.1Mpa \Tg(Alb1-cre)7Gsc/0 |
involves: C57BL/6 * FVB/N | J:118336 | View | ||||
| steatotic liver disease | \Ldlrtm1Her/\Ldlrtm1Her | involves: 129S7/SvEvBrd * C57BL/6 | J:175559 | View | ||||
| steatotic liver disease | \Lepob/\Lepob | B6.Cg-Lepob/JRj | J:220381 | View | ||||
| steatotic liver disease | \Lgals3tm1Ftl/\Lgals3tm1Ftl | involves: 129S2/SvPas * CD-1 | J:116073, J:221030 | View | ||||
| steatotic liver disease | \Lrp6tm1Arma/\Lrp6tm1Arma | C57BL/6-Lrp6tm1Arma | J:225450 | View | ||||
| steatotic liver disease | \Mc4rtm1Lowl/\Mc4rtm1Lowl | involves: 129S4/SvJae * C57BL/6J | J:177386 | View | ||||
| steatotic liver disease |
\Ptentm1Hwu/\Ptentm1Hwu \Speer6-ps1Tg(Alb-cre)21Mgn/\Speer6-ps1+ |
involves: 129S4/SvJae * C57BL/6 * DBA | J:216841 | View | ||||
| steatotic liver disease |
\Ptentm2Mak/\Ptentm2Mak \Speer6-ps1Tg(Alb-cre)21Mgn/\Speer6-ps1+ |
involves: 129P2/OlaHsd * C57BL/6 * C57BL/6J * DBA | J:90905 | View | ||||
| steatotic liver disease |
\Sirt1tm1.2Cxd/\Sirt1tm1.2Cxd \Tg(Alb1-cre)1Dlr/? |
involves: 129S6/SvEvTac * FVB/N | J:179193 | View | ||||
| steatotic liver disease | \Tg(Mup3-Plau)350-2Eps/? | C57BL/6-Tg(Mup3-Plau)350-2Eps | J:233146 | View | ||||
| | intrahepatic cholestasis |
\Atp8b1tm1Nbf/\Atp8b1tm1Nbf \Portm1Wolf/\Portm1Wolf \Speer6-ps1Tg(Alb-cre)21Mgn/\Speer6-ps1+ |
involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6 * DBA | J:215915 | View | |||
| progressive familial intrahepatic cholestasis 4 |
\Tjp1tm1.1Whun/\Tjp1tm1.1Whun \Tjp2tm2Whun/\Tjp2tm2Whun \Speer6-ps1Tg(Alb-cre)21Mgn/\Speer6-ps1+ |
involves: 129S6/SvEvTac * C57BL/6 * C57BL/6N * C57BL/6NTac * DBA/2 | J:306936 | View | ||||
| Transgenes and Other Mutations | hepatitis | \Tg(KRT18*R89C)22Rgo/0 | involves: FVB/N | J:241700 | View | |||
| hepatitis | \Tg(KRT18*R89C)30Rgo/0 | involves: FVB/N | J:241700 | View | ||||
| hepatitis | \Tg(KRT18*R89C)50Rgo/0 | involves: FVB/N | J:241700 | View | ||||
| hepatocellular carcinoma |
\Rb1tm3Tyj/\Rb1tm3Tyj \Tg(tetO-MYC)36aBop/0 \Tg(Cebpb-tTA)5Bjd/0 |
involves: FVB/N * NMRI | J:172430 | View | ||||
| hepatocellular carcinoma | \Tg(Alb1HBV)44Bri/0 | C57BL/6J-Tg(Alb1HBV)44Bri/J | J:223921 | View | ||||
| hepatocellular carcinoma | \Tg(Alb-E2F1)8Sst/0 | involves: C57BL/6J * CBA/J | J:65354, J:101128, J:170790 | View | ||||
| hepatocellular carcinoma | \Tg(Alb-HBx)A112Tfts/0 | involves: C57BL/6 | J:104728 | View | ||||
| hepatocellular carcinoma | \Tg(Alb-HRAS*G12V)28Yu/0 | involves: C57BL/6J * CBA/J | J:107083, J:238319 | View | ||||
| hepatocellular carcinoma | \Tg(Alb-PDGFC)#Jcam/0 | involves: C57BL/6 | J:211984 | View | ||||
| hepatocellular carcinoma | \Tg(Alb-SND1)3aDsar/0 | involves: C57BL/6 * CBA | J:242582 | View | ||||
| hepatocellular carcinoma | \Tg(Alb-TAg)1Gjh/0 | C3.Cg-Tg(Alb-TAg)1Gjh | J:105110 | View | ||||
| hepatocellular carcinoma | \Tg(Alb-TAg)#Arnd/0 | C3Fe.Cg-Tg(Alb-TAg)#Arnd | J:171880 | View | ||||
| hepatocellular carcinoma |
\Tg(Cebpb-tTA)5Bjd/0 \Tg(tetO-MYC,-OVAL)#Gtgm/0 |
B6J.Cg-Tg(Cebpb-tTA)5Bjd Tg(tetO-MYC,-OVAL)#Gtgm | J:186226 | View | ||||
| hepatocellular carcinoma | \Tg(HBV-HCV)Kko/0 | C57BL/6N-Tg(HBV-HCV)Kko | J:69727 | View | ||||
| hepatocellular carcinoma | \Tg(HBx)3Yu/0 | involves: C57BL/6 * DBA | J:56196 | View | ||||
| hepatocellular carcinoma | \Tg(Myl2-FGF19)1Dfre/? | involves: FVB | J:77160, J:187236 | View | ||||
| hepatocellular carcinoma | \Tg(SERPINA1-TAg)1812Jtsb/0 | involves: C3H * C57BL/6 * ICR | J:101633 | View | ||||
| hepatocellular carcinoma | \Tg(SERPINC1-SV40)A1Pbr/0 | involves: C57BL/6 * DBA/2 | J:101541 | View | ||||
| hepatocellular carcinoma | \Tg(SERPINC1-SV40)A1Pbr/\Tg(SERPINC1-SV40)A1Pbr | involves: C57BL/6 * DBA/2 | J:101541 | View | ||||
| hepatocellular carcinoma |
\Tg(tetO-MET)23Rwng/0 \Tg(Cebpb-tTA)5Bjd/0 |
involves: FVB/N * NMRI | J:69731 | View | ||||
| hepatocellular carcinoma |
\Tg(tetO-MYC)36aBop/0 \Tg(Cebpb-tTA)5Bjd/0 |
involves: FVB/N * NMRI | J:93899, J:186226, J:172430 | View | ||||
| hepatocellular carcinoma | X/\Tg(SERPINC1-SV40)BPbr | involves: C57BL/6 * DBA/2 | J:101541, J:84204 | View | ||||
| metabolic dysfunction-associated steatotic liver disease | \Tg(Alb-SREBF1_ic)#Jkot/0 | involves: C57BL/6 | J:249664 | View | ||||
| metabolic dysfunction-associated steatotic liver disease | \Tg(aP2-SREBF1c)9884Reh/0 | involves: C57BL/6J * SJL | J:249664 | View | ||||
| steatotic liver disease | \Tg(Alb-PDGFC)#Jcam/0 | involves: C57BL/6 | J:96979 | View | ||||
| Additional Complex Models | hepatocellular carcinoma |
\Col1a1tm1(tetO-URI1)Ndj/\Col1a1+ \Tg(Cebpb-tTA)#Bjd/0 |
B6.Cg-Col1a1tm1(tetO-URI1)Ndj Tg(Cebpb-tTA)#Bjd | J:217463 | View | |||
| hepatocellular carcinoma |
\Col1a1tm1(tetO-URI1)Ndj/\Col1a1tm1(tetO-URI1)Ndj \Tg(Cebpb-tTA)#Bjd/0 |
B6.Cg-Col1a1tm1(tetO-URI1)Ndj Tg(Cebpb-tTA)#Bjd | J:217463 | View | ||||
| hepatocellular carcinoma |
\Rb1tm3Tyj/\Rb1tm3Tyj \Rbl1tm1Tyj/\Rbl1tm1Tyj \Rbl2tm2.1Tyj/\Rbl2tm2.1Tyj |
involves: 129S2/SvPas * 129S4/SvJae * C57BL/6 | J:177573 | View | ||||
| hepatocellular carcinoma |
\Stk3tm1Jav/\Stk3tm1Jav \Stk4Gt(AJ0315)Wtsi/\Stk4Gt(AJ0315)Wtsi \Speer6-ps1Tg(Alb-cre)21Mgn/\Speer6-ps1+ |
involves: 129 * 129P2/OlaHsd * C57BL/6 * DBA | J:238319 | View | ||||
| hepatocellular carcinoma |
\Tg(IRS1)1Mhep/0 \Tg(SERPINA1-HBVX)1655Jtsb/0 |
involves: C3H * C57BL/6 * FVB * ICR | J:227278 | View | ||||
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No similarity to the expected human disease phenotype was found.
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| Disease Term | Allelic Composition | Genetic Background | Reference | Phenotypes | ||||
| NOT Models | Alagille syndrome | \Jag1tm1Grid/\Jag1+ | involves: 129S1/Sv * C57BL/6 * FVB | J:54907 | View | |||
| intrahepatic cholestasis | \Atp8b1tm1Nbf/\Atp8b1tm1Nbf | involves: 129S1/SvImJ * 129S4/SvJae | J:89817 | View | ||||