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Phenotypes Associated with This Genotype
Genotype
MGI:3719416
Allelic
Composition		 TxnipHyplip1/TxnipHyplip1
Genetic
Background		 involves: CAST/Ei * HcB19/Dem
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
TxnipHyplip1 mutation (0 available); any Txnip mutation (51 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
neoplasm
increased hepatocellular carcinoma incidence ( J:112292 )
• 52 of 108 mice develop tumors

liver/biliary system
increased hepatocellular carcinoma incidence ( J:112292 )
• 52 of 108 mice develop tumors

Mouse Models of Human Disease
 DO ID OMIM ID(s) Ref(s)
hepatocellular carcinoma DOID:684 OMIM:114550
 J:112292

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory