hepatocellular carcinoma Disease Ontology Browser

Mouse Models

Human Disease Modeled: hepatocellular carcinoma
Associated Mouse Gene: Apc

Allelic Composition	Genetic Background	Reference	Phenotypes
Apctm2.1Cip/Apctm2.1Cip	involves: 129P2/OlaHsd * C57BL/6N	J:94721	View

Mouse Models

Human Disease Modeled: hepatocellular carcinoma
Associated Mouse Gene: Nr1h4

Allelic Composition	Genetic Background	Reference	Phenotypes
Nr1h4tm1Gonz/Nr1h4tm1Gonz	involves: 129X1/SvJ * C57BL/6	J:118204, J:170790	View
Nr1h4tm1Gonz/Nr1h4tm1Gonz	involves: 129X1/SvJ * C57BL/6N	J:121075, J:170790	View

Mouse Models

Human Disease Modeled: hepatocellular carcinoma
Associated Mouse Gene: Abcb4

Allelic Composition	Genetic Background	Reference	Phenotypes
Abcb4tm1Bor/Abcb4tm1Bor	either: (involves: 129P2/OlaHsd) or (involves: 129P2/OlaHsd * FVB/N)	J:21232	View

Mouse Models

Human Disease Modeled: hepatocellular carcinoma
Associated Mouse Gene: Cdkn1a

Allelic Composition	Genetic Background	Reference	Phenotypes
Cdkn1atm1(HBsAg)Xya/Cdkn1atm1(HBsAg)Xya	either: (involves: 129S6/SvEvTac * C57BL/6) or (involves: 129S6/SvEvTac * Black Swiss)	J:88078	View
Cdkn1atm2(HBx)Xya/Cdkn1atm2(HBx)Xya	either: (involves: 129S6/SvEvTac * C57BL/6) or (involves: 129S6/SvEvTac * Black Swiss)	J:88078	View
Cdkn1atm1(HBsAg)Xya/Cdkn1a+	either: (involves: 129S6/SvEvTac * C57BL/6) or (involves: 129S6/SvEvTac * Black Swiss)	J:88078	View
Cdkn1atm2(HBx)Xya/Cdkn1a+	either: (involves: 129S6/SvEvTac * C57BL/6) or (involves: 129S6/SvEvTac * Black Swiss)	J:88078	View

Mouse Models

Human Disease Modeled: hepatocellular carcinoma
Associated Mouse Gene: Foxm1

Allelic Composition	Genetic Background	Reference	Phenotypes
Foxm1tm1Rhc/Foxm1tm1Rhc	involves: 129X1/SvJ	J:89472	View

Mouse Models

Human Disease Modeled: hepatocellular carcinoma
Associated Mouse Gene: Gnmt

Allelic Composition	Genetic Background	Reference	Phenotypes
Gnmttm1Ymac/Gnmttm1Ymac	involves: 129 * C57BL/6	J:146081	View

Mouse Models

Human Disease Modeled: hepatocellular carcinoma
Associated Mouse Gene: Iqgap2

Allelic Composition	Genetic Background	Reference	Phenotypes
Iqgap2tm1Vs/Iqgap2tm1Vs	involves: 129S4/SvJae	J:205882	View

Mouse Models

Human Disease Modeled: hepatocellular carcinoma
Associated Mouse Gene: Krt18

Allelic Composition	Genetic Background	Reference	Phenotypes
Krt18tm1Tmm/Krt18tm1Tmm	involves: 129P2/OlaHsd	J:309021	View

Mouse Models

Human Disease Modeled: hepatocellular carcinoma
Associated Mouse Gene: Mcm9

Allelic Composition	Genetic Background	Reference	Phenotypes
Mcm9Gt(AW0655)Wtsi/Mcm9Gt(AW0655)Wtsi	involves: 129P2/OlaHsd * C3HeB/FeJ	J:177420	View
Mcm9Gt(XG743)Byg/Mcm9Gt(XG743)Byg	involves: 129P2/OlaHsd * C3HeB/FeJ	J:177420	View
Mcm9Gt(AW0655)Wtsi/Mcm9Gt(XG743)Byg	involves: 129P2/OlaHsd * C3HeB/FeJ	J:177420	View

Mouse Models

Human Disease Modeled: hepatocellular carcinoma
Associated Mouse Gene: Myc

Allelic Composition	Genetic Background	Reference	Phenotypes
Tg(Pklr-Myc)73Ak/0	B6.Cg-Tg(Pklr-Myc)73Ak	J:184496	View
Tg(HBVX,-Myc)#Skp/Tg(HBVX,-Myc)#Skp	Not Specified	J:81098, J:202732	View
Gtf2ird1Tg(Alb1-Myc)166.8Sst/Gtf2ird1+ Tg(Alb-E2F1)8Sst/0	involves: C57BL/6 * CBA	J:101128, J:170790	View
Tg(Pklr-Myc)73Ak/0	involves: C57BL/6 * DBA	J:185488	View
Lect2tm1Ymg/Lect2tm1Ymg Tg(Pklr-Myc)73Ak/0	B6.Cg-Lect2^tm1Ymg Tg(Pklr-Myc)73Ak	J:184496	View
Tg(Alb1-Myc)#Sst/0 Tg(MtTGFA)Lmb/0	involves: C57BL/6 * CBA * CD-1	J:176432	View
Tcra-Jtm1Tgi/Tcra-Jtm1Tgi Tg(Pklr-Myc)73Ak/0	B6.Cg-Tcra-J^tm1Tgi Tg(Pklr-Myc)73Ak	J:184496	View
Tg(tetO-MYC)36aBop/0 Tg(Cebpb-tTA)5Bjd/0	involves: FVB/N * NMRI	J:93899, J:186226, J:172430	View
Rb1tm3Tyj/Rb1tm3Tyj Tg(tetO-MYC)36aBop/0 Tg(Cebpb-tTA)5Bjd/0	involves: FVB/N * NMRI	J:172430	View
Gtf2ird1Tg(Alb1-Myc)166.8Sst/Gtf2ird1+ Tg(MtTGFA)42Lmb/0	involves: C57BL/6 * CBA * CD-1	J:34434	View

Mouse Models

Human Disease Modeled: hepatocellular carcinoma
Associated Mouse Gene: Nfe2l1

Allelic Composition	Genetic Background	Reference	Phenotypes
Nfe2l1tm1Jefc/Nfe2l1tm1Ywk Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+	involves: 129X1/SvJ * C57BL/6J	J:97188	View

Mouse Models

Human Disease Modeled: hepatocellular carcinoma
Associated Mouse Gene: Plau

Allelic Composition	Genetic Background	Reference	Phenotypes
Tg(Mup3-Plau)350-2Eps/?	C57BL/6-Tg(Mup3-Plau)350-2Eps	J:233146	View

Mouse Models

Human Disease Modeled: hepatocellular carcinoma
Associated Mouse Gene: Pten

Allelic Composition	Genetic Background	Reference	Phenotypes
Ptentm2Mak/Ptentm2Mak Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+	involves: 129P2/OlaHsd * C57BL/6 * C57BL/6J * DBA	J:90905	View
Ptentm2Mak/Ptentm2Mak Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+	involves: 129P2/OlaHsd * C57BL/6 * DBA	J:138099	View
Ptentm1Hwu/Ptentm1Hwu Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+	involves: 129S4/SvJae * C57BL/6 * DBA	J:218587	View

Mouse Models

Human Disease Modeled: hepatocellular carcinoma
Associated Mouse Gene: Sav1

Allelic Composition	Genetic Background	Reference	Phenotypes
Sav1tm2.1Dlim/Sav1tm2.1Dlim Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+	involves: C57BL/6 * DBA	J:238319	View

Mouse Models

Human Disease Modeled: hepatocellular carcinoma
Associated Mouse Gene: Txnip

Allelic Composition	Genetic Background	Reference	Phenotypes
TxnipHyplip1/TxnipHyplip1	HcB19/Dem-Txnip^Hyplip1	J:112292	View
TxnipHyplip1/TxnipHyplip1	involves: CAST/Ei * HcB19/Dem	J:112292	View
TxnipHyplip1/Txnip+	involves: CAST/Ei * HcB19/Dem	J:112292	View

Mouse Models

Human Disease Modeled: hepatocellular carcinoma
Associated Mouse Gene: Uaca

Allelic Composition	Genetic Background	Reference	Phenotypes
Uacatm1Kiy/Uacatm1Kiy	B6.129P2-Uaca^tm1Kiy	J:157049	View

Mouse Models

Human Disease Modeled: hepatocellular carcinoma

Allelic Composition	Genetic Background	Reference	Phenotypes
Tg(Alb-HRAS*G12V)28Yu/0	involves: C57BL/6J * CBA/J	J:107083, J:238319	View

Mouse Models

Human Disease Modeled: hepatocellular carcinoma

Allelic Composition	Genetic Background	Reference	Phenotypes
Lect2tm1Ymg/Lect2tm1Ymg Tg(Pklr-Myc)73Ak/0	B6.Cg-Lect2^tm1Ymg Tg(Pklr-Myc)73Ak	J:184496	View

Mouse Models

Human Disease Modeled: hepatocellular carcinoma

Allelic Composition	Genetic Background	Reference	Phenotypes
Tg(tetO-MET)23Rwng/0 Tg(Cebpb-tTA)5Bjd/0	involves: FVB/N * NMRI	J:69731	View

Mouse Models

Human Disease Modeled: hepatocellular carcinoma
Associated Mouse Transgene: Tg(Alb1HBV)44Bri

Allelic Composition	Genetic Background	Reference	Phenotypes
Tg(Alb1HBV)44Bri/0	C57BL/6J-Tg(Alb1HBV)44Bri/J	J:223921	View

Mouse Models

Human Disease Modeled: hepatocellular carcinoma
Associated Mouse Transgene: Tg(Alb-E2F1)8Sst

Allelic Composition	Genetic Background	Reference	Phenotypes
Tg(Alb-E2F1)8Sst/0	involves: C57BL/6J * CBA/J	J:65354, J:101128, J:170790	View
Gtf2ird1Tg(Alb1-Myc)166.8Sst/Gtf2ird1+ Tg(Alb-E2F1)8Sst/0	involves: C57BL/6 * CBA	J:101128, J:170790	View

Mouse Models

Human Disease Modeled: hepatocellular carcinoma
Associated Mouse Transgene: Tg(Alb-HBx)A112Tfts

Allelic Composition	Genetic Background	Reference	Phenotypes
Tg(Alb-HBx)A112Tfts/0	involves: C57BL/6	J:104728	View

Mouse Models

Human Disease Modeled: hepatocellular carcinoma
Associated Mouse Transgene: Tg(Alb-HRAS*G12V)28Yu

Allelic Composition	Genetic Background	Reference	Phenotypes
Tg(Alb-HRAS*G12V)28Yu/0	involves: C57BL/6J * CBA/J	J:107083, J:238319	View

Mouse Models

Human Disease Modeled: hepatocellular carcinoma
Associated Mouse Transgene: Tg(Alb-PDGFC)#Jcam

Allelic Composition	Genetic Background	Reference	Phenotypes
Tg(Alb-PDGFC)#Jcam/0	involves: C57BL/6	J:211984	View

Mouse Models

Human Disease Modeled: hepatocellular carcinoma
Associated Mouse Transgene: Tg(Alb-SND1)3aDsar

Allelic Composition	Genetic Background	Reference	Phenotypes
Tg(Alb-SND1)3aDsar/0	involves: C57BL/6 * CBA	J:242582	View

Mouse Models

Human Disease Modeled: hepatocellular carcinoma
Associated Mouse Transgene: Tg(Alb-TAg)1Gjh

Allelic Composition	Genetic Background	Reference	Phenotypes
Tg(Alb-TAg)1Gjh/0	C3.Cg-Tg(Alb-TAg)1Gjh	J:105110	View

Mouse Models

Human Disease Modeled: hepatocellular carcinoma
Associated Mouse Transgene: Tg(Alb-TAg)#Arnd

Allelic Composition	Genetic Background	Reference	Phenotypes
Tg(Alb-TAg)#Arnd/0	C3Fe.Cg-Tg(Alb-TAg)#Arnd	J:171880	View

Mouse Models

Human Disease Modeled: hepatocellular carcinoma
Associated Mouse Transgene: Tg(HBV-HCV)Kko

Allelic Composition	Genetic Background	Reference	Phenotypes
Tg(HBV-HCV)Kko/0	C57BL/6N-Tg(HBV-HCV)Kko	J:69727	View

Mouse Models

Human Disease Modeled: hepatocellular carcinoma
Associated Mouse Transgene: Tg(HBVX*,-Myc)#Skp

Allelic Composition	Genetic Background	Reference	Phenotypes
Tg(HBVX,-Myc)#Skp/Tg(HBVX,-Myc)#Skp	Not Specified	J:81098, J:202732	View

Mouse Models

Human Disease Modeled: hepatocellular carcinoma
Associated Mouse Transgene: Tg(HBx)3Yu

Allelic Composition	Genetic Background	Reference	Phenotypes
Tg(HBx)3Yu/0	involves: C57BL/6 * DBA	J:56196	View

Mouse Models

Human Disease Modeled: hepatocellular carcinoma
Associated Mouse Transgene: Tg(Mup3-Plau)350-2Eps

Allelic Composition	Genetic Background	Reference	Phenotypes
Tg(Mup3-Plau)350-2Eps/?	C57BL/6-Tg(Mup3-Plau)350-2Eps	J:233146	View

Mouse Models

Human Disease Modeled: hepatocellular carcinoma
Associated Mouse Transgene: Tg(Myl2-FGF19)1Dfre

Allelic Composition	Genetic Background	Reference	Phenotypes
Tg(Myl2-FGF19)1Dfre/?	involves: FVB	J:77160, J:187236	View

Mouse Models

Human Disease Modeled: hepatocellular carcinoma
Associated Mouse Transgene: Tg(Pklr-Myc)73Ak

Allelic Composition	Genetic Background	Reference	Phenotypes
Tg(Pklr-Myc)73Ak/0	B6.Cg-Tg(Pklr-Myc)73Ak	J:184496	View
Tg(Pklr-Myc)73Ak/0	involves: C57BL/6 * DBA	J:185488	View
Lect2tm1Ymg/Lect2tm1Ymg Tg(Pklr-Myc)73Ak/0	B6.Cg-Lect2^tm1Ymg Tg(Pklr-Myc)73Ak	J:184496	View
Tcra-Jtm1Tgi/Tcra-Jtm1Tgi Tg(Pklr-Myc)73Ak/0	B6.Cg-Tcra-J^tm1Tgi Tg(Pklr-Myc)73Ak	J:184496	View

Mouse Models

Human Disease Modeled: hepatocellular carcinoma
Associated Mouse Transgene: Tg(SERPINA1-TAg)1812Jtsb

Allelic Composition	Genetic Background	Reference	Phenotypes
Tg(SERPINA1-TAg)1812Jtsb/0	involves: C3H * C57BL/6 * ICR	J:101633	View

Mouse Models

Human Disease Modeled: hepatocellular carcinoma
Associated Mouse Transgene: Tg(SERPINC1-SV40)A1Pbr

Allelic Composition	Genetic Background	Reference	Phenotypes
Tg(SERPINC1-SV40)A1Pbr/Tg(SERPINC1-SV40)A1Pbr	involves: C57BL/6 * DBA/2	J:101541	View
Tg(SERPINC1-SV40)A1Pbr/0	involves: C57BL/6 * DBA/2	J:101541	View

Mouse Models

Human Disease Modeled: hepatocellular carcinoma
Associated Mouse Transgene: Tg(SERPINC1-SV40)BPbr

Allelic Composition	Genetic Background	Reference	Phenotypes
X/Tg(SERPINC1-SV40)BPbr	involves: C57BL/6 * DBA/2	J:101541, J:84204	View

Mouse Models

Human Disease Modeled: hepatocellular carcinoma
Associated Mouse Transgene: Tg(tetO-MET)23Rwng

Allelic Composition	Genetic Background	Reference	Phenotypes
Tg(tetO-MET)23Rwng/0 Tg(Cebpb-tTA)5Bjd/0	involves: FVB/N * NMRI	J:69731	View

Mouse Models

Human Disease Modeled: hepatocellular carcinoma
Associated Mouse Transgene: Tg(tetO-MYC)36aBop

Allelic Composition	Genetic Background	Reference	Phenotypes
Tg(tetO-MYC)36aBop/0 Tg(Cebpb-tTA)5Bjd/0	involves: FVB/N * NMRI	J:93899, J:186226, J:172430	View
Rb1tm3Tyj/Rb1tm3Tyj Tg(tetO-MYC)36aBop/0 Tg(Cebpb-tTA)5Bjd/0	involves: FVB/N * NMRI	J:172430	View

Mouse Models

Human Disease Modeled: hepatocellular carcinoma
Associated Mouse Transgene: Tg(tetO-MYC,-OVAL)#Gtgm

Allelic Composition	Genetic Background	Reference	Phenotypes
Tg(Cebpb-tTA)5Bjd/0 Tg(tetO-MYC,-OVAL)#Gtgm/0	B6J.Cg-Tg(Cebpb-tTA)5Bjd Tg(tetO-MYC,-OVAL)#Gtgm	J:186226	View

Mouse Models

Human Disease Modeled: hepatocellular carcinoma

Allelic Composition	Genetic Background	Reference	Phenotypes
Col1a1tm1(tetO-URI1)Ndj/Col1a1+ Tg(Cebpb-tTA)#Bjd/0	B6.Cg-Col1a1^{tm1(tetO-URI1)Ndj} Tg(Cebpb-tTA)#Bjd	J:217463	View

Mouse Models

Human Disease Modeled: hepatocellular carcinoma

Allelic Composition	Genetic Background	Reference	Phenotypes
Col1a1tm1(tetO-URI1)Ndj/Col1a1tm1(tetO-URI1)Ndj Tg(Cebpb-tTA)#Bjd/0	B6.Cg-Col1a1^{tm1(tetO-URI1)Ndj} Tg(Cebpb-tTA)#Bjd	J:217463	View

Mouse Models

Human Disease Modeled: hepatocellular carcinoma

Allelic Composition	Genetic Background	Reference	Phenotypes
Rb1tm3Tyj/Rb1tm3Tyj Rbl1tm1Tyj/Rbl1tm1Tyj Rbl2tm2.1Tyj/Rbl2tm2.1Tyj	involves: 129S2/SvPas * 129S4/SvJae * C57BL/6	J:177573	View

Mouse Models

Human Disease Modeled: hepatocellular carcinoma

Allelic Composition	Genetic Background	Reference	Phenotypes
Stk3tm1Jav/Stk3tm1Jav Stk4Gt(AJ0315)Wtsi/Stk4Gt(AJ0315)Wtsi Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+	involves: 129 * 129P2/OlaHsd * C57BL/6 * DBA	J:238319	View

Mouse Models

Human Disease Modeled: hepatocellular carcinoma

Allelic Composition	Genetic Background	Reference	Phenotypes
Tg(IRS1)1Mhep/0 Tg(SERPINA1-HBVX)1655Jtsb/0	involves: C3H * C57BL/6 * FVB * ICR	J:227278	View

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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