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Tg(Alb-TAg)#Arnd
Transgene Detail
Summary
Symbol: Tg(Alb-TAg)#Arnd
Name: transgene insertion, Bernd Arnold
MGI ID: MGI:5000250
Synonyms: Alb-SV40TAg(ind), AST
Transgene: Tg(Alb-TAg)#Arnd  Location: unknown  
Alliance: Tg(Alb-TAg)#Arnd page
Transgene
origin
Strain of Origin:  (CBA x DBA/2)F1
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Mutation detailsThe mouse promoter drives hepatocyte-specific expression of the SV40 T antigen preceded by a floxed neo STOP cassette. Removal of the STOP cassette is required to achieve expression of TAg. The pound symbol (#) is used when no line is specified and/or lines are pooled. (J:171880)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:171880 Stahl S, et al., Tumor agonist peptides break tolerance and elicit effective CTL responses in an inducible mouse model of hepatocellular carcinoma. Immunol Lett. 2009 Mar 24;123(1):31-7
All:  6 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory