All Phenotypes Tg(Alb-TAg)#Arnd MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Tg(Alb-TAg)#Arnd
transgene insertion, Bernd Arnold
MGI:5000250

Summary

2 genotypes

Allelic Composition	Tg(Alb-TAg)#Arnd/0
Genetic Background	C3Fe.Cg-Tg(Alb-TAg)#Arnd

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Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

neoplasm

• mice treated with an adenovirus expressing cre exhibit massive multinodular hepatocellular carcinomas unlike control mice

liver/biliary system

• mice treated with an adenovirus expressing cre exhibit massive multinodular hepatocellular carcinomas unlike control mice

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
hepatocellular carcinoma		DOID:684	OMIM:114550	J:171880

Allelic Composition	Tg(Alb-TAg)#Arnd/0
Genetic Background	(C3Fe.Cg-Tg(Alb-TAg)#Arnd x C57BL/6N)F1

Find Mice

Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

immune system

abnormal immune system physiology ( J:171880 )

• mice treated with an adenovirus expressing cre are tolerant to SV40 T antigen unlike control mice

• however, immunization with the agonistic peptide IVc-l breaks tolerance

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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