D2.Cg-(D4Mit42-D4Smh6b) Pkhd1<cyli>/EiJ Strain Detail MGI Mouse MGI:2173881

D2.Cg-(D4Mit42-D4Smh6b) Pkhd1^cyli/EiJ Strain Detail

Summary

3 associated mutations

Phenotype Overview

Blue squares indicate phenotypes directly attributed to mutations/alleles in this strain.

adipose tissue	behavior/neurological	cardiovascular system	cellular	craniofacial	digestive/alimentary system	embryo	endocrine/exocrine glands	growth/size/body	hearing/vestibular/ear	hematopoietic system	homeostasis/metabolism	immune system	integument	limbs/digits/tail	liver/biliary system	mortality/aging	muscle	neoplasm	nervous system	normal phenotype	pigmentation	renal/urinary system	reproductive system	respiratory system	skeleton	taste/olfaction	vision/eye

Click cells to view annotations.

Human Diseases

	model 1
Caroli syndrome	√

Key

√

disease model

expected model not found

1 associated strain record at IMSR

IMSR	Repository	IMSR Strain	Why Matched
JAX:003604	JAX	D2.Cg-(D4Mit42-D4Smh6b) Pkhd1^cyli/EiJ	exact match to ID

Earliest

J:343537 Yang C, et al., Pkhd1 cyli/cyli mice have altered renal Pkhd1 mRNA processing and hormonally sensitive liver disease. J Mol Med. 2023;101(9):1141-1115
All

1

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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