schizophrenia Disease Ontology Browser

Mouse Models

Human Disease Modeled: schizophrenia
Associated Mouse Gene: Akt1

Allelic Composition	Genetic Background	Reference	Phenotypes
\Akt1tm1Mbb/\Akt1tm1Mbb	involves: 129P2/OlaHsd * C57BL/6	J:185487	View

Mouse Models

Human Disease Modeled: schizophrenia
Associated Mouse Gene: Chrna7

Allelic Composition	Genetic Background	Reference	Phenotypes
\Chrna7tm1Bay/\Chrna7tm1Bay	B6.129S7-Chrna7^tm1Bay/J	J:214099	View

Mouse Models

Human Disease Modeled: schizophrenia
Associated Mouse Gene: Disc1

Allelic Composition	Genetic Background	Reference	Phenotypes
\Disc1tm1Kara/\Disc1tm1Kara	B6.129S6-Disc1^tm1Kara	J:107244	View
\Disc1Rgsc1390/\Disc1Rgsc1390	B6.Cg-Disc1^Rgsc1390	J:120634	View
\Disc1m1H/\Disc1m1H	B6N.C(C3H)-Disc1^m1H	J:229661	View
\Tg(Camk2a-ESR1/Disc1*)2698.1Sva/0	involves: C57BL/6 * C57BL/6NTac	J:127235	View
\Tg(Disc1/EGFP)M19Sshe/0	involves: C57BL/6JCrl * CBA/CaCrl	J:143557	View
\Disc1tm1Kara/\Disc1+	B6.129S6-Disc1^tm1Kara	J:107244	View
\Disc1tm1(DISC1/DISC1FP1,DISC1FP1/DISC1,DISC1)Xzho/\Disc1del	129S2/SvPasCrl-Disc1^del Disc1^{tm1(DISC1/DISC1FP1,DISC1FP1/DISC1,DISC1)Xzho}	J:214737	View

Mouse Models

Human Disease Modeled: schizophrenia
Associated Mouse Gene: Dtnbp1

Allelic Composition	Genetic Background	Reference	Phenotypes
\Dtnbp1sdy/\Dtnbp1sdy	B6J.D2-Dtnbp1^sdy	J:197066, J:223954	View
\Dtnbp1sdy/\Dtnbp1sdy	DBA/2J-Dtnbp1^sdy/J	J:143912	View

Mouse Models

Human Disease Modeled: schizophrenia
Associated Mouse Gene: Ncstn

Allelic Composition	Genetic Background	Reference	Phenotypes
\Ncstntm1.1Sud/\Ncstntm1.1Sud \Olig1tm1(cre)Rth/\Olig1+	involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ	J:234705	View

Mouse Models

Human Disease Modeled: schizophrenia
Associated Mouse Gene: Avpr1a

Allelic Composition	Genetic Background	Reference	Phenotypes
\Avpr1atm1Dgen/\Avpr1atm1Dgen	involves: 129P2/OlaHsd * C57BL/6	J:101679	View

Mouse Models

Human Disease Modeled: schizophrenia
Associated Mouse Gene: Bace1

Allelic Composition	Genetic Background	Reference	Phenotypes
\Bace1tm1Pcw/\Bace1tm1Pcw	involves: 129S1/Sv * 129X1/SvJ * C57BL/6J	J:133643	View

Mouse Models

Human Disease Modeled: schizophrenia
Associated Mouse Gene: Chst3

Allelic Composition	Genetic Background	Reference	Phenotypes
\Chst3tm1Dgen/\Chst3tm1Dgen	involves: 129P2/OlaHsd * C57BL/6	J:101679	View

Mouse Models

Human Disease Modeled: schizophrenia
Associated Mouse Gene: ckr

Allelic Composition	Genetic Background	Reference	Phenotypes
\ckr/\ckr	involves: C3H/HeRos * C57BL/10Ros	J:87399	View

Mouse Models

Human Disease Modeled: schizophrenia
Associated Mouse Gene: Cplx2

Allelic Composition	Genetic Background	Reference	Phenotypes
\Cplx2tm1Bros/\Cplx2tm1Bros	B6NCrl.Cg-Cplx2^tm1Bros	J:175056	View

Mouse Models

Human Disease Modeled: schizophrenia
Associated Mouse Gene: Csmd1

Allelic Composition	Genetic Background	Reference	Phenotypes
\Csmd1tm1Lex/\Csmd1tm1Lex	involves: 129S5/SvEvBrd * C57BL/6NTac	J:209700	View

NOT Models
No similarity to the expected human disease phenotype was found.

Allelic Composition	Genetic Background	Reference	Phenotypes
\Csmd1tm1Lex/\Csmd1tm1Lex	B6;129S5-Csmd1^tm1Lex/Mmucd	J:194991	View

Mouse Models

Human Disease Modeled: schizophrenia
Associated Mouse Gene: Ctsc

Allelic Composition	Genetic Background	Reference	Phenotypes
\Ctsctm1Dgen/\Ctsctm1Dgen	involves: 129P2/OlaHsd * C57BL/6	J:101679	View

Mouse Models

Human Disease Modeled: schizophrenia
Associated Mouse Gene: Gnas

Allelic Composition	Genetic Background	Reference	Phenotypes
\Tg(Camk2a-tTA)1Mmay/0 \Tg(tetO-Gnas)1593Mpke/0	B6.Cg-Tg(Camk2a-tTA)1Mmay Tg(tetO-Gnas)1593Mpke	J:166114	View

Mouse Models

Human Disease Modeled: schizophrenia
Associated Mouse Gene: Grin1

Allelic Composition	Genetic Background	Reference	Phenotypes
\Grin1tm1Bhk/\Grin1tm1Bhk	involves: 129P2/OlaHsd * C57BL/6 * DBA/2	J:57125	View

Mouse Models

Human Disease Modeled: schizophrenia
Associated Mouse Gene: Grm5

Allelic Composition	Genetic Background	Reference	Phenotypes
\Grm5tm1Rod/\Grm5tm1Rod	B6.129-Grm5^tm1Rod	J:268239	View

Mouse Models

Human Disease Modeled: schizophrenia
Associated Mouse Gene: Hivep2

Allelic Composition	Genetic Background	Reference	Phenotypes
\Hivep2tm1Sis/\Hivep2tm1Sis	either: (involves: BALB/cA * C57BL/6NCrlj * CBA/JNCrlj) or (involves: C57BL/6J * C57BL/6NCrlj * CBA/JNCrlj)	J:263351	View
\Hivep2tm1Sis/\Hivep2tm1Sis	involves: C57BL/6NCrlj * CBA/JNCrlj	J:271912	View

Mouse Models

Human Disease Modeled: schizophrenia
Associated Mouse Gene: Kif3b

Allelic Composition	Genetic Background	Reference	Phenotypes
\Kif3btm1Noh/\Kif3b+	involves: 129S4/SvJae * C57BL/6J	J:286227	View

Mouse Models

Human Disease Modeled: schizophrenia
Associated Mouse Gene: Lrrtm1

Allelic Composition	Genetic Background	Reference	Phenotypes
\Lrrtm1tm1.1Jaru/\Lrrtm1tm1.1Jaru	involves: C57BL/6 * C57BL/6J	J:174350	View

Mouse Models

Human Disease Modeled: schizophrenia
Associated Mouse Gene: Magi2

Allelic Composition	Genetic Background	Reference	Phenotypes
\Tg(Camk2a-Magi2)1Shlee/?	C57BL/6J-Tg(Camk2a-Magi2)1Shlee	J:218971	View

Mouse Models

Human Disease Modeled: schizophrenia
Associated Mouse Gene: Map2k7

Allelic Composition	Genetic Background	Reference	Phenotypes
\Map2k7tm1Pngr/\Map2k7+	involves: 129P2/OlaHsd * C57BL/6J	J:188339	View

Mouse Models

Human Disease Modeled: schizophrenia
Associated Mouse Gene: Map6

Allelic Composition	Genetic Background	Reference	Phenotypes
\Map6tm1Job/\Map6tm1Job	either: 129S2/SvPas or (involves: 129S2/SvPas * BALB/c)	J:79099	View
\Map6tm1Job/\Map6tm1Job	involves: 129S2/SvPas * C57BL/6	J:225083	View
\Map6tm1Job/\Map6+	involves: 129S2/SvPas * C57BL/6	J:225083	View

Mouse Models

Human Disease Modeled: schizophrenia
Associated Mouse Gene: Mdk

Allelic Composition	Genetic Background	Reference	Phenotypes
\Mdktm1Tmu/\Mdktm1Tmu	B6.129S2-Mdk^tm1Tmu	J:151029	View

Mouse Models

Human Disease Modeled: schizophrenia
Associated Mouse Gene: Nlgn2

Allelic Composition	Genetic Background	Reference	Phenotypes
\Nlgn2tm1.1Gchn/\Nlgn2tm1.1Gchn	involves: 129S/SvEv * C57BL/6J	J:272181	View

Mouse Models

Human Disease Modeled: schizophrenia
Associated Mouse Gene: Nr4a2

Allelic Composition	Genetic Background	Reference	Phenotypes
\Nr4a2tm1Tpe/\Nr4a2+	B6.129P2-Nr4a2^tm1Tpe	J:147544	View

Mouse Models

Human Disease Modeled: schizophrenia
Associated Mouse Gene: Nrg1

Allelic Composition	Genetic Background	Reference	Phenotypes
\Nrg1tm2Zhou/\Nrg1+	involves: 129S4/SvJae * C57BL/6	J:81106	View

Mouse Models

Human Disease Modeled: schizophrenia
Associated Mouse Gene: Nrg3

Allelic Composition	Genetic Background	Reference	Phenotypes
\Nrg3tm1.1Plet/\Nrg3tm1.1Plet	involves: C57BL/6	J:270199	View

Mouse Models

Human Disease Modeled: schizophrenia
Associated Mouse Gene: Nrxn1

Allelic Composition	Genetic Background	Reference	Phenotypes
\Nrxn1tm1Sud/\Nrxn1tm1Sud	involves: 129 * C57BL/6	J:153748	View

Mouse Models

Human Disease Modeled: schizophrenia
Associated Mouse Gene: Pdgfrb

Allelic Composition	Genetic Background	Reference	Phenotypes
\Pdgfrbtm1Msas/\Pdgfrbtm1Msas \Tg(Nes-cre)1Nogu/0	B6J.Cg-Pdgfrb^tm1Msas Tg(Nes-cre)1Nogu	J:229179	View

Mouse Models

Human Disease Modeled: schizophrenia
Associated Mouse Gene: Plcb1

Allelic Composition	Genetic Background	Reference	Phenotypes
\Plcb1tm1Hssh/\Plcb1tm1Hssh	involves: 129/Sv * C57BL/6	J:151070	View

Mouse Models

Human Disease Modeled: schizophrenia
Associated Mouse Gene: Ppara

Allelic Composition	Genetic Background	Reference	Phenotypes
\Pparaem1Tyrb/\Pparaem1Tyrb	C57BL/6J-Ppara^em1Tyrb	J:313946	View

Mouse Models

Human Disease Modeled: schizophrenia
Associated Mouse Gene: Ppm1g

Allelic Composition	Genetic Background	Reference	Phenotypes
\Ppm1gtm1Dgen/\Ppm1g+	involves: 129P2/OlaHsd * C57BL/6	J:101679	View

Mouse Models

Human Disease Modeled: schizophrenia
Associated Mouse Gene: Ppp3r1

Allelic Composition	Genetic Background	Reference	Phenotypes
\Ppp3r1tm1Stl/\Ppp3r1tm1Stl \Tg(Camk2a-cre)CW2Stl/0	C57BL/6-Ppp3r1^tm1Stl Tg(Camk2a-cre)CW2Stl	J:73203, J:84640	View

Mouse Models

Human Disease Modeled: schizophrenia
Associated Mouse Gene: Reln

Allelic Composition	Genetic Background	Reference	Phenotypes
\Relnrl/\Reln+	B6C3Fe a/a-Reln^rl/J	J:107996	View
\Relnrl/\Reln+	B6.Cg-Reln^rl	J:223944	View

Mouse Models

Human Disease Modeled: schizophrenia
Associated Mouse Gene: Setd1a

Allelic Composition	Genetic Background	Reference	Phenotypes
\Setd1aem1Yzhg/\Setd1a+	B6.Cg-Setd1a^em1Yzhg	J:328716	View

Mouse Models

Human Disease Modeled: schizophrenia
Associated Mouse Gene: Shank3

Allelic Composition	Genetic Background	Reference	Phenotypes
\Shank3tm4.1Gfng/\Shank3tm4.1Gfng	involves: 129S1/Sv * 129X1/SvJ * C57BL/6J	J:230887	View

Mouse Models

Human Disease Modeled: schizophrenia
Associated Mouse Gene: Slc6a1

Allelic Composition	Genetic Background	Reference	Phenotypes
\Slc6a1tm1Mlit/\Slc6a1tm1Mlit	B6.129S1-Slc6a1^tm1Mlit	J:204368	View

Mouse Models

Human Disease Modeled: schizophrenia
Associated Mouse Gene: Slc6a3

Allelic Composition	Genetic Background	Reference	Phenotypes
\Slc6a3tm1Mca/\Slc6a3tm1Mca	involves: 129P2/OlaHsd	J:31328	View

Mouse Models

Human Disease Modeled: schizophrenia
Associated Mouse Gene: Snap25

Allelic Composition	Genetic Background	Reference	Phenotypes
\Snap25Bdr/\Snap25+	involves: BALB/cAnNCrl	J:119733	View

Mouse Models

Human Disease Modeled: schizophrenia
Associated Mouse Gene: Sp4

Allelic Composition	Genetic Background	Reference	Phenotypes
\Sp4tm3(Sp4)Krc/\Sp4tm3(Sp4)Krc	involves: 129S1/Sv * 129X1/SvJ * Black Swiss	J:163637	View

Mouse Models

Human Disease Modeled: schizophrenia
Associated Mouse Gene: Srgap3

Allelic Composition	Genetic Background	Reference	Phenotypes
\Srgap3tm1.1Zi/\Srgap3tm1.1Zi	B6.129(SJL)-Srgap3^tm1.1Zi	J:192388	View

Mouse Models

Human Disease Modeled: schizophrenia
Associated Mouse Gene: Srr

Allelic Composition	Genetic Background	Reference	Phenotypes
\Srrrgsc1872/\Srrrgsc1872	C57BL/6JJcl-Srr^rgsc1872	J:151337	View
\Srrtm1.2Jtc/\Srrtm1.2Jtc	involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6	J:158266	View

Mouse Models

Human Disease Modeled: schizophrenia
Associated Mouse Gene: Syngap1

Allelic Composition	Genetic Background	Reference	Phenotypes
\Syngap1tm1Rlh/\Syngap1+	involves: 129S/SvEv * 129S1/Sv * 129X1/SvJ * C57BL/6J	J:194146	View

Mouse Models

Human Disease Modeled: schizophrenia
Associated Mouse Gene: Taar1

Allelic Composition	Genetic Background	Reference	Phenotypes
\Taar1tm1Tdw/\Taar1tm1Tdw	involves: 129S1/Sv * C57BL/6J	J:141501	View

Mouse Models

Human Disease Modeled: schizophrenia
Associated Mouse Gene: Tcf4

Allelic Composition	Genetic Background	Reference	Phenotypes
\Tg(Thy1-Tcf4)1Mjro/0	involves: C57BL/6N * FVB/N	J:197081	View

Mouse Models

Human Disease Modeled: schizophrenia
Associated Mouse Gene: Ywhaz

Allelic Composition	Genetic Background	Reference	Phenotypes
\YwhazGt(OST432062)Lex/\YwhazGt(OST432062)Lex	either: B6.129S5-Ywhaz^{Gt(OST432062)Lex} or C.129S5-Ywhaz^{Gt(OST432062)Lex} or (involves: 129S5/SvEvBrd * 129T2/SvEmsWehi))	J:217297	View

Mouse Models

Human Disease Modeled: schizophrenia
Associated Mouse Gene: Zfp521

Allelic Composition	Genetic Background	Reference	Phenotypes
\Zfp521tm1Nohk/\Zfp521tm1Nohk	B6J.Cg-Zfp521^tm1Nohk	J:214267	View

Mouse Models

Human Disease Modeled: schizophrenia
Associated Mouse Gene: Zfp804a

Allelic Composition	Genetic Background	Reference	Phenotypes
\Zfp804aem1Yqd/\Zfp804aem1Yqd	involves: C57BL/6 * FVB/N	J:312498	View

Mouse Models

Human Disease Modeled: schizophrenia
Associated Mouse Gene: Zic2

Allelic Composition	Genetic Background	Reference	Phenotypes
\Zic2tm1Jaru/\Zic2+	involves: 129S4/SvJae * C57BL/6J	J:174352	View

Mouse Models

Human Disease Modeled: schizophrenia

Allelic Composition	Genetic Background	Reference	Phenotypes
\Del(16Dgcr2-Hira)3Aam/\+	involves: 129S7/SvEvBrd * C57BL/6J	J:158957	View

Mouse Models

Human Disease Modeled: schizophrenia

Allelic Composition	Genetic Background	Reference	Phenotypes
\Del(16Dgcr2-Hira)3Aam/\+	involves: 129S7/SvEvBrd * C57BL/6J	J:158957	View

Mouse Models

Human Disease Modeled: schizophrenia

Allelic Composition	Genetic Background	Reference	Phenotypes
\Del(16Dgcr2-Hira)3Aam/\+	involves: 129S7/SvEvBrd * C57BL/6J	J:158957	View

NOT Models
No similarity to the expected human disease phenotype was found.

Allelic Composition	Genetic Background	Reference	Phenotypes
\Rtn4rtm1Gogo/\Rtn4rtm1Gogo	involves: 129 * C57BL/6J	J:130368	View
\Rtn4rrgsc1836/\Rtn4rrgsc1836	C57BL/6JJcl-Rtn4r^rgsc1836	J:176996	View

Mouse Models

Human Disease Modeled: schizophrenia

Allelic Composition	Genetic Background	Reference	Phenotypes
\Del(16Dgcr2-Hira)3Aam/\+	involves: 129S7/SvEvBrd * C57BL/6J	J:158957	View

Mouse Models

Human Disease Modeled: schizophrenia
Associated Mouse Complex/Cluster/Region: Del(16Dgcr2-Hira)3Aam

Allelic Composition	Genetic Background	Reference	Phenotypes
\Del(16Dgcr2-Hira)3Aam/\+	involves: 129S7/SvEvBrd * C57BL/6J	J:158957	View

Mouse Models

Human Disease Modeled: schizophrenia
Associated Mouse Transgene: Tg(Camk2a-DISC1)10Asaw

Allelic Composition	Genetic Background	Reference	Phenotypes
\Tg(Camk2a-DISC1)10Asaw/0	C57BL/6-Tg(Camk2a-DISC1)10Asaw	J:124683, J:194985	View

Mouse Models

Human Disease Modeled: schizophrenia
Associated Mouse Transgene: Tg(Camk2a-DISC1)37Asaw

Allelic Composition	Genetic Background	Reference	Phenotypes
\Tg(Camk2a-DISC1)37Asaw/\Tg(Camk2a-DISC1)37Asaw	C57BL/6-Tg(Camk2a-DISC1)37Asaw	J:194985	View
\Tg(Camk2a-DISC1)37Asaw/0	C57BL/6-Tg(Camk2a-DISC1)37Asaw	J:124683, J:194985	View

Mouse Models

Human Disease Modeled: schizophrenia
Associated Mouse Transgene: Tg(Camk2a-ESR1/Disc1*)2698.1Sva

Allelic Composition	Genetic Background	Reference	Phenotypes
\Tg(Camk2a-ESR1/Disc1*)2698.1Sva/0	involves: C57BL/6 * C57BL/6NTac	J:127235	View

Mouse Models

Human Disease Modeled: schizophrenia
Associated Mouse Transgene: Tg(Camk2a-Magi2)1Shlee

Allelic Composition	Genetic Background	Reference	Phenotypes
\Tg(Camk2a-Magi2)1Shlee/?	C57BL/6J-Tg(Camk2a-Magi2)1Shlee	J:218971	View

Mouse Models

Human Disease Modeled: schizophrenia
Associated Mouse Transgene: Tg(Disc1/EGFP)M19Sshe

Allelic Composition	Genetic Background	Reference	Phenotypes
\Tg(Disc1/EGFP)M19Sshe/0	involves: C57BL/6JCrl * CBA/CaCrl	J:143557	View

Mouse Models

Human Disease Modeled: schizophrenia
Associated Mouse Transgene: Tg(tetO-Gnas)1593Mpke

Allelic Composition	Genetic Background	Reference	Phenotypes
\Tg(Camk2a-tTA)1Mmay/0 \Tg(tetO-Gnas)1593Mpke/0	B6.Cg-Tg(Camk2a-tTA)1Mmay Tg(tetO-Gnas)1593Mpke	J:166114	View

Mouse Models

Human Disease Modeled: schizophrenia
Associated Mouse Transgene: Tg(tetO-HMOX1)6Hyms

Allelic Composition	Genetic Background	Reference	Phenotypes
\Tg(GFAP-tTA)6Hyms/0 \Tg(tetO-HMOX1)6Hyms/0	involves: FVB/N	J:186620	View

Mouse Models

Human Disease Modeled: schizophrenia
Associated Mouse Transgene: Tg(tetO-NRG1_i4)6Ajla

Allelic Composition	Genetic Background	Reference	Phenotypes
\Tg(Eno2tTA)5030Nes/0 \Tg(tetO-NRG1_i4)6Ajla/0	involves: C57BL/6 * C57BL/6J * SJL	J:231737	View

Mouse Models

Human Disease Modeled: schizophrenia
Associated Mouse Transgene: Tg(Thy1-Tcf4)1Mjro

Allelic Composition	Genetic Background	Reference	Phenotypes
\Tg(Thy1-Tcf4)1Mjro/0	involves: C57BL/6N * FVB/N	J:197081	View

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