Lrrtm1tm1.1Jaru
Targeted Allele Detail
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Symbol: |
Lrrtm1tm1.1Jaru |
Name: |
leucine rich repeat transmembrane neuronal 1; targeted mutation 1.1, Jun Aruga |
MGI ID: |
MGI:5085889 |
Gene: |
Lrrtm1 Location: Chr6:77219672-77234774 bp, + strand Genetic Position: Chr6, 33.89 cM
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Alliance: |
Lrrtm1tm1.1Jaru page
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Approach toward inanimate objects is altered in Lrrtm1tm1.1Jaru/Lrrtm1tm1.1Jaru mice
Show the 2 phenotype image(s) involving this allele.
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Germline Transmission: |
Earliest citation of germline transmission:
J:174350
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Parent Cell Line: |
CMTI-2 (ES Cell)
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Strain of Origin: |
C57BL/6J
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Allele Type: |
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Targeted (Null/knockout) |
Mutations: |
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Insertion, Intragenic deletion
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Mutation details: A loxP site was inserted into exon 2 upstream of the translation initiation site. An FRT-flanked neo cassette with a 3' loxP site was inserted downstream of exon 2. Cre-mediated recombination removed the coding region and neo cassette.
(J:174350)
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Generation of the Lrrtm1tm1.1Jaru allele |
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Lrrtm1 Mutation: |
23 strains or lines available
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Original: |
J:174350 Takashima N, et al., Impaired cognitive function and altered hippocampal synapse morphology in mice lacking lrrtm1, a gene associated with schizophrenia. PLoS One. 2011;6(7):e22716 |
All: |
1 reference(s) |
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