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Phenotypes Associated with This Genotype
Genotype
MGI:3606703
Allelic
Composition		 Chst3tm1Dgen/Chst3tm1Dgen
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Chst3tm1Dgen mutation (1 available); any Chst3 mutation (17 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
behavior/neurological
increased coping response ( J:101679 )
• decreased time immobile during a tail suspension test

nervous system
decreased prepulse inhibition ( J:101679 )
• decreased prepulse inhibition
• stimulus processing deficit similar to schizophrenia

Mouse Models of Human Disease
 DO ID OMIM ID(s) Ref(s)
schizophrenia DOID:5419 OMIM:181500
 J:101679

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory