Tg(Disc1/EGFP)M19Sshe
Transgene Detail

Summary

• Symbol: Tg(Disc1/EGFP)M19Sshe
• Name: transgene insertion M19, Sanbing Shen
• MGI ID: MGI:5428215
• Synonyms: Disc1tr, Disc1tr-EGFP
• Transgene: Tg(Disc1/EGFP)M19Sshe Location: unknown
• Alliance: Tg(Disc1/EGFP)M19Sshe page

Transgene origin

• Strain of Origin: C57BL/6JCrl x CBA/CaCrl

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence, Reporter)
• Mutation: Insertion
• Tg(Disc1/EGFP)M19Sshe expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Disc1 (MGI:2447658)

• Mutation details: The mouse BAC RP23-236F19 was modified by inserting an EGFP inframe with Disc1 exon 8. Line M19, with 2 copies of the transgene, was generated. The insertion of EGFP truncates Disc1. (J:143557)

Disease models

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:143557 Shen S, et al., Schizophrenia-related neural and behavioral phenotypes in transgenic mice expressing truncated Disc1. J Neurosci. 2008 Oct 22;28(43):10893-904
• All: 5 reference(s)