About   Help   FAQ
Dtnbp1sdy
Spontaneous Allele Detail
Summary
Symbol: Dtnbp1sdy
Name: dystrobrevin binding protein 1; sandy
MGI ID: MGI:1856628
Synonyms: Bloc1s8sdy, Dys-, Dys KO, sdy, sdy-
Gene: Dtnbp1  Location: Chr13:45075552-45155614 bp, - strand  Genetic Position: Chr13, 21.73 cM
Alliance: Dtnbp1sdy page
Mutation
origin
Strain of Origin:  DBA/2J
Mutation
description
Allele Type:    Spontaneous
Mutation:    Intragenic deletion
 
Mutation detailsThe mutation in the sandy mouse has been attributed to a deletion in the Dtnbp1 gene from intron 5 nucleotide 3701 to intron 7 nucleotide 12377. The deletion results in the loss of 52 amino acids from position 119-172 and abolishes expression of the protein. Western analysis did not detect protein in hippocampus tissue from homozygous mutant mice. (J:85123, J:169460)
Inheritance:    Recessive
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Disease models
Loading...
Expression
In Mice Carrying this Mutation: 10 assay results
In Structures Affected by this Mutation: 6 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Dtnbp1 Mutation:  27 strains or lines available
References
Original:  J:14267 Sweet HO, Sandy (sdy). Mouse Genome. 1990;86:237
All:  61 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
03/19/2024
MGI 6.23
The Jackson Laboratory