Excel File Text File *Disease is associated/modeled with this Gene or a homolog. More...
      Disease Term Human Homologs Mouse Homologs Mouse Models Homology Source
     autoimmune polyendocrine syndrome type 1 AIRE* Aire* 9 models HomoloGene and HGNC
CINCA Syndrome NLRP3* Nlrp3* 1 model HomoloGene and HGNC
familial Mediterranean fever MEFV* Mefv* 4 models HomoloGene and HGNC
immune dysregulation-polyendocrinopathy-enteropathy-X-linked syndrome FOXP3* Foxp3* 2 models HomoloGene and HGNC
systemic lupus erythematosus DNASE1* Dnase1* 1 model HomoloGene and HGNC
systemic lupus erythematosus PDCD1* Pdcd1* 2 models HomoloGene and HGNC
systemic lupus erythematosus FCGR2B* Fcgr2b* 2 models HomoloGene
     autoimmune hemolytic anemia TSLP Tslp* 1 model HomoloGene and HGNC
autoimmune hypersensitivity disease GPR132 Gpr132* 1 model HomoloGene and HGNC
autoimmune hypersensitivity disease CD200 Cd200* 1 model HomoloGene and HGNC
autoimmune hypersensitivity disease C9orf72 C9orf72* 3 models HomoloGene and HGNC
bullous pemphigoid COL17A1 Col17a1* 1 model HGNC
cutaneous lupus erythematosus TREX1 Trex1* 1 model HomoloGene and HGNC
Guillain-Barre syndrome AIRE Aire* 1 model HomoloGene and HGNC
Guillain-Barre syndrome CD86 Cd86* 1 model HomoloGene and HGNC
IgG4-related disease LAT Lat* 1 model HomoloGene and HGNC
multiple sclerosis LRCH1 Lrch1* 1 model HomoloGene and HGNC
multiple sclerosis PRF1 Prf1* 1 model HomoloGene and HGNC
multiple sclerosis TNF Tnf* 4 models HomoloGene and HGNC
Sjogren's syndrome AIRE Aire* 3 models HomoloGene and HGNC
Sjogren's syndrome CCR7 Ccr7* 1 model HomoloGene and HGNC
Sjogren's syndrome CYP19A1 Cyp19a1* 2 models HomoloGene and HGNC
Sjogren's syndrome E2F1 E2f1* 1 model HomoloGene and HGNC
Sjogren's syndrome FAS Fas* 4 models HomoloGene and HGNC
Sjogren's syndrome ID3 Id3* 2 models HomoloGene and HGNC
Sjogren's syndrome IL2 Il2* 1 model HomoloGene and HGNC
Sjogren's syndrome IL2RA Il2ra* 1 model HomoloGene and HGNC
Sjogren's syndrome IL4 Il4* 2 models HomoloGene and HGNC
Sjogren's syndrome MAP3K14 Map3k14* 1 model HomoloGene and HGNC
Sjogren's syndrome MUC19 Muc19* 1 model HGNC
Sjogren's syndrome NFKBIA Nfkbia* 1 model HomoloGene and HGNC
Sjogren's syndrome plt* 1 model
Sjogren's syndrome RORC Rorc* 1 model HomoloGene and HGNC
Sjogren's syndrome ST14 St14* 1 model HomoloGene and HGNC
Sjogren's syndrome TGFB1 Tgfb1* 1 model HomoloGene and HGNC
Sjogren's syndrome THBS1 Thbs1* 1 model HomoloGene and HGNC
Sjogren's syndrome TNFSF13B Tnfsf13b* 1 model HomoloGene and HGNC
Sjogren's syndrome TRAF3IP2 Traf3ip2* 1 model HomoloGene and HGNC
systemic lupus erythematosus TRAF3IP2 Traf3ip2* 2 models HomoloGene and HGNC
systemic lupus erythematosus RO60 Ro60* 3 models HomoloGene and HGNC
systemic lupus erythematosus RC3H1 Rc3h1* 1 model HomoloGene and HGNC
systemic lupus erythematosus RASSF5 Rassf5* 1 model HomoloGene and HGNC
systemic lupus erythematosus RASGRP1 Rasgrp1* 1 model HomoloGene and HGNC
systemic lupus erythematosus PTPRC Ptprc* 3 models HomoloGene and HGNC
systemic lupus erythematosus PRDM1 Prdm1* 1 model HomoloGene and HGNC
systemic lupus erythematosus PPARG Pparg* 1 model HomoloGene and HGNC
systemic lupus erythematosus POLB Polb* 1 model HomoloGene and HGNC
systemic lupus erythematosus PLD4 Pld4* 1 model HomoloGene and HGNC
systemic lupus erythematosus MTA2 Mta2* 1 model HomoloGene and HGNC
systemic lupus erythematosus MAN2A1 Man2a1* 1 model HomoloGene and HGNC
systemic lupus erythematosus LYN Lyn* 2 models HomoloGene and HGNC
systemic lupus erythematosus LBR Lbr* 1 model HomoloGene and HGNC
systemic lupus erythematosus JUNB Junb* 1 model HomoloGene and HGNC
systemic lupus erythematosus JAK1 Jak1* 1 model HomoloGene and HGNC
systemic lupus erythematosus INPP5D Inpp5d* 1 model HomoloGene and HGNC
systemic lupus erythematosus IKZF3 Ikzf3* 1 model HomoloGene and HGNC
systemic lupus erythematosus IFIH1 Ifih1* 2 models HomoloGene and HGNC
systemic lupus erythematosus GADD45A Gadd45a* 2 models HomoloGene and HGNC
systemic lupus erythematosus FAS Fas* 5 models HomoloGene and HGNC
systemic lupus erythematosus EP300 Ep300* 1 model HomoloGene and HGNC
systemic lupus erythematosus DEF6 Def6* 1 model HomoloGene and HGNC
systemic lupus erythematosus C1QA C1qa* 1 model HomoloGene and HGNC
systemic lupus erythematosus RUBCN Rubcn* 1 model HomoloGene and HGNC
systemic lupus erythematosus RXRA Rxra* 1 model HomoloGene and HGNC
systemic lupus erythematosus TIMD4 Timd4* 1 model HomoloGene and HGNC
systemic lupus erythematosus TLR7 Tlr7* 1 model HomoloGene and HGNC
systemic lupus erythematosus CYBB Cybb* 1 model HomoloGene and HGNC
systemic lupus erythematosus CDKN1A Cdkn1a* 2 models HomoloGene and HGNC
systemic lupus erythematosus CD40LG Cd40lg* 1 model HomoloGene and HGNC
systemic lupus erythematosus C4A, C4B C4b*, C4a 1 model HomoloGene and HGNC
systemic lupus erythematosus TNFRSF13B Tnfrsf13b* 1 model HomoloGene and HGNC
systemic lupus erythematosus BECN1 Becn1* 1 model HomoloGene and HGNC
systemic lupus erythematosus ATG7 Atg7* 1 model HomoloGene and HGNC
systemic lupus erythematosus ATG5 Atg5* 1 model HomoloGene and HGNC
systemic scleroderma FOSL2 Fosl2* 1 model HomoloGene and HGNC
systemic scleroderma FLI1 Fli1* 1 model HomoloGene and HGNC
systemic scleroderma FBN1 Fbn1* 3 models HomoloGene and HGNC
systemic scleroderma COL3A1 Col3a1* 1 model HomoloGene and HGNC
systemic scleroderma TGFBR1 Tgfbr1* 1 model HomoloGene and HGNC
     autoimmune hypersensitivity disease SIAE* Siae   HomoloGene and HGNC
autoimmune hypersensitivity disease FOXD3* Foxd3   HomoloGene and HGNC
autoimmune thrombocytopenic purpura FCGR2C*   HGNC
celiac disease HLA-DQA1* H2-Aa   HomoloGene
celiac disease CTLA4* Ctla4   HomoloGene and HGNC
celiac disease MYO9B* Myo9b   HomoloGene and HGNC
celiac disease HLA-DQB1* H2-Ab1   HomoloGene
Chilblain lupus TREX1* Trex1   HomoloGene and HGNC
Chilblain lupus SAMHD1* Samhd1   HomoloGene and HGNC
Guillain-Barre syndrome PMP22* Pmp22   HomoloGene and HGNC
multiple sclerosis HLA-DQB1* H2-Ab1   HomoloGene
multiple sclerosis HLA-DRB1*   HomoloGene
multiple sclerosis PDCD1* Pdcd1   HomoloGene and HGNC
multiple sclerosis TNFRSF1A* Tnfrsf1a 1 model HomoloGene and HGNC
STING-associated vasculopathy with onset in infancy STING1* Sting1   HomoloGene and HGNC
systemic lupus erythematosus CR2* Cr2   HomoloGene and HGNC
systemic lupus erythematosus CTLA4* Ctla4   HomoloGene and HGNC
systemic lupus erythematosus DNASE1L3* Dnase1l3   HomoloGene and HGNC
systemic lupus erythematosus FCGR2A* Fcgr3   HomoloGene
systemic lupus erythematosus IRF5* Irf5   HomoloGene and HGNC
systemic lupus erythematosus PTPN22* Ptpn22 1 model HomoloGene and HGNC
systemic lupus erythematosus STAT4* Stat4   HomoloGene and HGNC
systemic lupus erythematosus TLR5* Tlr5   HomoloGene and HGNC
systemic lupus erythematosus TREX1* Trex1   HomoloGene and HGNC

 
Transgenes and other genome features developed in mice to model this disease.
     Disease Term Transgenes and Other Genome Features Mouse Models
  autoimmune hemolytic anemia Tg(tetO/CMV-Tslp)#Sfz 1 model
  autoimmune hypersensitivity disease Tg(Cd4-BCL2*G101A*D102A*D103A)AWnt 1 model
  multiple sclerosis Tg(PLP1*)4Rsj 1 model
  multiple sclerosis Tg(Mbp-Pad2)28Fgm 2 models
  multiple sclerosis Tg(Gfap-TNF*)K21Gkl 2 models
  multiple sclerosis Tg(H2-Kb-Tcra,-Tcrb)1640Kurs 1 model
  multiple sclerosis Tg(Tnf)6074Gkl 2 models
  Sjogren's syndrome Tg(Tnfsf13b)1Fma 1 model
  Sjogren's syndrome Tg(CD2-Rorc)#Staka 1 model
  Sjogren's syndrome Tg(Emu-TXLNA)1Amjr 1 model
  Sjogren's syndrome Tg(Psp-Rbbp4)1Yoha 1 model
  systemic lupus erythematosus Igh-J 4 models
  systemic lupus erythematosus Tg(ACTB-TNFRSF6B)754Jwu 1 model
  systemic lupus erythematosus Tg(Igh-V-CD40lg)#Tsub 1 model
  systemic lupus erythematosus Tg(Tlr7)1Boll 1 model
  systemic lupus erythematosus Yaa 5 models
  systemic scleroderma Tg(H2-K-Fosl2,EGFP)13Wag 1 model