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Gstp3 Gene Detail
Summary
  • Symbol
    Gstp3
  • Name
    glutathione S-transferase pi 3
  • Synonyms
    BC021614, MGC:37914
  • Feature Type
    protein coding gene
  • IDs
    MGI:2385078
    NCBI Gene: 225884
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr19:4107477-4109569 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 19, 3.77 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    46 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2385078
 protein coding gene Chr19:4107470-4109587 (-)
129S1/SvImJ MGP_129S1SvImJ_G0024643
 protein coding gene Chr19:887207-889176 (-)
A/J MGP_AJ_G0024609
 protein coding gene Chr19:861625-863594 (-)
AKR/J MGP_AKRJ_G0024582
 protein coding gene Chr19:876203-878172 (-)
BALB/cJ MGP_BALBcJ_G0024609
 protein coding gene Chr19:847251-849220 (-)
C3H/HeJ MGP_C3HHeJ_G0024377
 protein coding gene Chr19:875030-876999 (-)
C57BL/6NJ MGP_C57BL6NJ_G0025057
 protein coding gene Chr19:917581-919550 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0022486
 protein coding gene Chr19:804886-806830 (-)
CAST/EiJ MGP_CASTEiJ_G0023849
 protein coding gene Chr19:886026-887996 (-)
CBA/J MGP_CBAJ_G0024348
 protein coding gene Chr19:981769-983738 (-)
DBA/2J MGP_DBA2J_G0024476
 protein coding gene Chr19:817558-819527 (-)
FVB/NJ MGP_FVBNJ_G0024443
 protein coding gene Chr19:830875-832844 (-)
LP/J MGP_LPJ_G0024562
 protein coding gene Chr19:880749-882718 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0024473
 protein coding gene Chr19:927680-929649 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0025104
 protein coding gene Chr19:878968-880937 (-)
PWK/PhJ MGP_PWKPhJ_G0023595
 protein coding gene Chr19:864363-866314 (-)
SPRET/EiJ MGP_SPRETEiJ_G0023400
 protein coding gene Chr19:864472-866611 (-)
WSB/EiJ MGP_WSBEiJ_G0023911
 protein coding gene Chr19:864455-866424 (-)



Homology
more
  • Human Ortholog
    GSTP1, glutathione S-transferase pi 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    GSTP1, glutathione S-transferase pi 1
  • Synonyms
    DFN7, FAEES3, GST3, GSTP, HEL-S-22, PI
  • Links
    NCBI Gene ID: 2950
    neXtProt AC: NX_P09211
    UniProt: P09211

  • Chr Location
    11q13.2; chr11:67583742-67586656 (+)  GRCh38
Human Diseases
more
  • Diseases
    54 with human GSTP1 associations

Human Disease Mouse Models
      
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Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    4 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
    27
  • GO References
    2
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    753
  • Tissues
    1
  • cDNA Data
    38
  • Literature Summary
    3
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000058216 Ensembl Gene Model | MGI Sequence Detail 2093 C57BL/6J ±  kb
transcript ENSMUST00000189808 Ensembl | MGI Sequence Detail 708 Not Applicable  
polypeptide ENSMUSP00000140159 Ensembl | MGI Sequence Detail 210 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    2 Sequences
  • EC
    2.5.1.18
  • InterPro Domains
    IPR004046 Glutathione S-transferase, C-terminal
    IPR036282 Glutathione S-transferase, C-terminal domain superfamily
    IPR010987 Glutathione S-transferase, C-terminal-like
    IPR004045 Glutathione S-transferase, N-terminal
    IPR003082 Glutathione S-transferase, Pi class
    IPR036249 Thioredoxin-like superfamily
Molecular
Reagents
less
  • All nucleic 38
    cDNA 38

    Microarray probesets 3
References
more
  • Summaries
    All 24
    Developmental Gene Expression 3
    Gene Ontology 2
    Phenotypes 4
  • Earliest
    J:82808 Strausberg RL, et al., Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903
  • Latest
    J:306171 Liu X, et al., Glutathione S-transferase Pi (Gstp) proteins regulate neuritogenesis in the developing cerebral cortex. Hum Mol Genet. 2021 Mar 25;30(1):30-45
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory