atopic dermatitis Disease Ontology Browser

Disease Ontology Browser

atopic dermatitis (DOID:3310)
Alliance: disease page
Synonyms: allergic dermatitis; atopic eczema; Atopic neurodermatitis; Besnier's prurigo
Alt IDs: OMIM:603165, EFO:0000274, ICD10CM:L20, MESH:D003876, OMIM:PS603165, UMLS_CUI:C0011615
Definition: An allergic contact dermatitis that is a chronically relapsing inflammatory allergic response located_in the skin that causes itching and flaking.

Term Browser
Genes (44)
Models (29)

Disease References using Mouse Models (45)

Mouse Models

Human Disease Modeled: atopic dermatitis
Associated Mouse Gene: Il4

Allelic Composition	Genetic Background	Reference	Phenotypes
\Tg(KRT14-Il4)#Lsch/0	involves: BALB/cBy * C57BL/6	J:126285	View

Mouse Models

Human Disease Modeled: atopic dermatitis
Associated Mouse Gene: Il13

Allelic Composition	Genetic Background	Reference	Phenotypes
\Tg(KRT5-tTA)1216Glk/0 \Tg(tetO-Il13)1Tazh/0	B6.Cg-Tg(KRT5-tTA)1216Glk Tg(tetO-Il13)1Tazh	J:150232	View

Mouse Models

Human Disease Modeled: atopic dermatitis
Associated Mouse Gene: Il18

Allelic Composition	Genetic Background	Reference	Phenotypes
\Tg(KRT14-Il18)#Knak/0	C57BL/6-Tg(KRT14-Il18)#Knak	J:78602	View

Mouse Models

Human Disease Modeled: atopic dermatitis
Associated Mouse Transgene: Tg(APOC1)1Lmh

Allelic Composition	Genetic Background	Reference	Phenotypes
\Tg(APOC1)1Lmh/\Tg(APOC1)1Lmh	involves: C57BL/6	J:135501	View

Mouse Models

Human Disease Modeled: atopic dermatitis
Associated Mouse Transgene: Tg(CD2-Stat6*V625A*T626A)78Mhk

Allelic Composition	Genetic Background	Reference	Phenotypes
\Tg(CD2-Stat6V625AT626A)78Mhk/0	involves: C3H * C57BL/6	J:160119	View

Mouse Models

Human Disease Modeled: atopic dermatitis
Associated Mouse Transgene: Tg(KRT14-CASP1)1Miz

Allelic Composition	Genetic Background	Reference	Phenotypes
\Tg(KRT14-CASP1)1Miz/0	involves: C57BL/6	J:78602	View

Mouse Models

Human Disease Modeled: atopic dermatitis
Associated Mouse Transgene: Tg(KRT14-Il4)#Lsch

Allelic Composition	Genetic Background	Reference	Phenotypes
\Tg(KRT14-Il4)#Lsch/0	involves: BALB/cBy * C57BL/6	J:126285	View

Mouse Models

Human Disease Modeled: atopic dermatitis
Associated Mouse Transgene: Tg(KRT14-Il18)#Knak

Allelic Composition	Genetic Background	Reference	Phenotypes
\Tg(KRT14-Il18)#Knak/0	C57BL/6-Tg(KRT14-Il18)#Knak	J:78602	View

Mouse Models

Human Disease Modeled: atopic dermatitis
Associated Mouse Transgene: Tg(KRT14-VP16/NR1I2)13Sdub

Allelic Composition	Genetic Background	Reference	Phenotypes
\Tg(KRT14-VP16/NR1I2)13Sdub/?	involves: C57BL/6	J:258435	View

Mouse Models

Human Disease Modeled: atopic dermatitis
Associated Mouse Transgene: Tg(SV40-KLK7)1010Teg

Allelic Composition	Genetic Background	Reference	Phenotypes
\Tg(SV40-KLK7)1010Teg/0	involves: C57BL/6J * CBA	J:75714	View

Mouse Models

Human Disease Modeled: atopic dermatitis
Associated Mouse Transgene: Tg(tetO-Il13)1Tazh

Allelic Composition	Genetic Background	Reference	Phenotypes
\Tg(KRT5-tTA)1216Glk/0 \Tg(tetO-Il13)1Tazh/0	B6.Cg-Tg(KRT5-tTA)1216Glk Tg(tetO-Il13)1Tazh	J:150232	View

Mouse Models

Human Disease Modeled: atopic dermatitis
Associated Mouse Transgene: Tg(tetO/CMV-Tslp)#Sfz

Allelic Composition	Genetic Background	Reference	Phenotypes
\Tg(KRT5-rtTA)1Glk/0 \Tg(tetO/CMV-Tslp)#Sfz/0	involves: C3H * C57BL/6 * FVB/N	J:100506	View

Mouse Models

Human Disease Modeled: atopic dermatitis
Associated Mouse Gene: Adam17

Allelic Composition	Genetic Background	Reference	Phenotypes
\Adam17tm1.2Bbl/\Adam17tm1.2Bbl \Sox9tm3(cre)Crm/\Sox9+	B6.129(SJL)-Sox9^tm3(cre)Crm Adam17^tm1.2Bbl	J:229771	View

Mouse Models

Human Disease Modeled: atopic dermatitis
Associated Mouse Gene: Casp8

Allelic Composition	Genetic Background	Reference	Phenotypes
\Casp8tm1Hed/\Casp8tm1Hed \Tg(KRT14-cre)1Efu/0	Not Specified	J:167299	View

Mouse Models

Human Disease Modeled: atopic dermatitis
Associated Mouse Gene: Ctse

Allelic Composition	Genetic Background	Reference	Phenotypes
\Ctsetm1Kjy/\Ctsetm1Kjy	involves: C57BL/6	J:108745	View

Mouse Models

Human Disease Modeled: atopic dermatitis
Associated Mouse Gene: Nfkbia

Allelic Composition	Genetic Background	Reference	Phenotypes
\Nfkbiatm1Stw/\Nfkbiatm1Stw	involves: 129S1/Sv	J:32527	View

Mouse Models

Human Disease Modeled: atopic dermatitis
Associated Mouse Gene: Nfkbiz

Allelic Composition	Genetic Background	Reference	Phenotypes
\Nfkbiztm1Mamo/\Nfkbiztm1Mamo	involves: 129S7/SvEvBrd	J:95040	View

Mouse Models

Human Disease Modeled: atopic dermatitis
Associated Mouse Gene: Noa

Allelic Composition	Genetic Background	Reference	Phenotypes
\Noa/\Noa+	NOA	J:43274	View

Mouse Models

Human Disease Modeled: atopic dermatitis
Associated Mouse Gene: Relb

Allelic Composition	Genetic Background	Reference	Phenotypes
\Relbtm1Brv/\Relbtm1Brv	either: (involves: 129S2/SvPas) or (involves: C57BL/6) or (involves: 129S2/SvPas * C57BL/6)	J:63950	View

Mouse Models

Human Disease Modeled: atopic dermatitis
Associated Mouse Gene: Sharpin

Allelic Composition	Genetic Background	Reference	Phenotypes
\Sharpincpdm/\Sharpincpdm	C57BL/KaLawRij-Sharpin^cpdm	J:14539, J:31745, J:116833	View

Mouse Models

Human Disease Modeled: atopic dermatitis
Associated Mouse Gene: Tmem79

Allelic Composition	Genetic Background	Reference	Phenotypes
\Tmem79ma/\Tmem79ma	B6.CBACaGr-Tmem79^ma/J	J:202453	View
\Tmem79ma/\Tmem79ma	involves: C57BL/6JJcl * CBA/CaGr	J:202316	View

Mouse Models

Human Disease Modeled: atopic dermatitis
Associated Mouse Gene: Traf3ip2

Allelic Composition	Genetic Background	Reference	Phenotypes
\Traf3ip2adjm/\Traf3ip2adjm	A.KOR-Traf3ip2^adjm	J:162859	View
\Traf3ip2adjm/\Traf3ip2adjm	AK.KOR-Traf3ip2^adjm	J:162859	View
\Traf3ip2adjm/\Traf3ip2adjm	B6.KOR-Traf3ip2^adjm	J:162859	View
\Traf3ip2adjm/\Traf3ip2adjm	C.KOR-Traf3ip2^adjm	J:162859	View
\Traf3ip2adjm/\Traf3ip2adjm	KOR-Traf3ip2^adjm	J:162859	View

Mouse Models

Human Disease Modeled: atopic dermatitis
Associated Mouse Gene: Trpv3

Allelic Composition	Genetic Background	Reference	Phenotypes
\Trpv3Nh/\Trpv3+	involves: DS	J:42153	View

Mouse Models

Human Disease Modeled: atopic dermatitis
Associated Mouse Gene: Tslp

Allelic Composition	Genetic Background	Reference	Phenotypes
\Tg(KRT5-rtTA)1Glk/0 \Tg(tetO/CMV-Tslp)#Sfz/0	involves: C3H * C57BL/6 * FVB/N	J:100506	View

Mouse Models

Human Disease Modeled: atopic dermatitis
Associated Mouse Gene: Wasl

Allelic Composition	Genetic Background	Reference	Phenotypes
\Wasltm1.1Ttha/\Wasltm1.1Ttha \Tg(KRT14-cre)1Amc/0	involves: C57BL/6 * C57BL/6N * CBA	J:271857	View

Mouse Models

Human Disease Modeled: atopic dermatitis

Allelic Composition	Genetic Background	Reference	Phenotypes
\Fgfr1tm1Upir/\Fgfr1tm1Upir \Fgfr2tm1Dor/\Fgfr2tm1Dor \Tg(KRT5-cre)5132Jlj/0	involves: 129X1/SvJ * C57BL/6 * C57BL/6J * DBA/2J	J:221184	View

Mouse Models

Human Disease Modeled: atopic dermatitis

Allelic Composition	Genetic Background	Reference	Phenotypes
\Dock8tm1Ysfk/\Dock8tm1Ysfk \Tg(TcrAND)53Hed/0	involves: C57BL/6 * SJL	J:305132	View

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