Phenotypes Associated with This Genotype

Genotype
MGI:4820830

• Allelic Composition: Traf3ip2^adjm/Traf3ip2^adjm
• Genetic Background: KOR-Traf3ip2^adjm

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

premature death ( J:162859 )

immune system

increased IgE level ( J:162859 )

• elevated in all, however female mice displaying serum IgE levels two times higher than those of male mice until 10 wk of age

dermatitis ( J:162859 )

• apparent at 5 wk of age, and is localized mainly to the face, including the ears, becoming progressively more severe

reproductive system

female infertility ( J:162859 )

♀

integument

dermatitis ( J:162859 )

• apparent at 5 wk of age, and is localized mainly to the face, including the ears, becoming progressively more severe

thick epidermis ( J:162859 )

increased pruritus ( J:162859 )

hematopoietic system

increased IgE level ( J:162859 )

• elevated in all, however female mice displaying serum IgE levels two times higher than those of male mice until 10 wk of age

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
atopic dermatitis		DOID:3310	OMIM:603165 OMIM:PS603165	J:162859