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Cd36 Gene Detail
Summary
  • Symbol
    Cd36
  • Name
    CD36 molecule
  • Synonyms
    FAT, fatty acid translocase, Scarb3
  • Feature Type
    protein coding gene
  • IDs
    MGI:107899
    NCBI Gene: 12491
  • Alliance
    genome feature page
  • Transcription Start Sites
    64 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:17986688-18093799 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 5, 8.11 cM
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    3165 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_107899
 protein coding gene Chr5:17986680-18093828 (-)
129S1/SvImJ ENSMUSG00200009767
 protein coding gene Chr5:13598537-13701792 (-)
A/J ENSMUSG00195038330
 protein coding gene Chr5:13092947-13200073 (-)
AKR/J ENSMUSG00220036289
 protein coding gene Chr5:13051221-13162572 (-)
BALB/cJ ENSMUSG00180023579
 protein coding gene Chr5:12950052-13057169 (-)
C3H/HeJ ENSMUSG00175025592
 protein coding gene Chr5:14901985-15009104 (-)
C57BL/6NJ ENSMUSG00215018044
 protein coding gene Chr5:13517518-13624631 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0026975
 protein coding gene Chr5:12998926-13098211 (-)
CAST/EiJ ENSTCUG00005002994
 protein coding gene Chr5:13248867-13349799 (-)
CBA/J ENSMUSG00210004663
 protein coding gene Chr5:13941372-14048488 (-)
DBA/2J ENSMUSG00185016872
 protein coding gene Chr5:15429529-15536870 (-)
FVB/NJ ENSMUSG00205027418
 protein coding gene Chr5:12655043-12761555 (-)
JF1/MsJ ENSUMUG00000001561
 protein coding gene Chr5:20068060-20175817 (-)
LP/J ENSMUSG00230002845
 protein coding gene Chr5:19919479-20022738 (-)
NOD/ShiLtJ ENSMUSG00190004417
 protein coding gene Chr5:12968030-13079088 (-)
NZO/HlLtJ ENSMUSG00225008721
 protein coding gene Chr5:25318698-25425810 (-)
PWK/PhJ ENSLUMG00010033562
 protein coding gene Chr5:13086381-13194005 (-)
SPRET/EiJ ENSMSPG00010026983
 protein coding gene Chr5:13867355-13903997 (-)
WSB/EiJ ENSIUOG00005030920
 protein coding gene Chr5:15784527-15891576 (-)



Homology
more
  • Human Ortholog
    CD36, CD36 molecule (CD36 blood group)
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CD36, CD36 molecule (CD36 blood group)
  • Synonyms
    BDPLT10, CHDS7, FAT, GP3B, GP4, GPIV, PASIV, SCARB3
  • Links
    NCBI Gene ID: 948
    UniProt: P16671

  • Chr Location
    7q21.11; chr7:80369532-80679277 (+)  GRCh38
Human Diseases
more
  • Diseases
    1 with Cd36 mouse models; 8 with human CD36 associations

Human Disease Mouse Models
      
IDs
 View 1 model
      
IDs
IDs
IDs
IDs
IDs
IDs
IDs
Click on a disease name to see all genes associated with that disease.

  • Mutations/Alleles
    1 with disease annotations
  • References
    2 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    110 phenotypes from 5 alleles in 9 genetic backgrounds
    8 phenotypes from multigenic genotypes
    325 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Homozygous mutant mice exhibit an immunodeficiency phenotype, are susceptible to S. aureus infection and develop ocular pterygium. Mice homozygous for disruptions in this gene display abnormal lipid homeostasis which affects energy utilization in the heart.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    236
  • GO References
    35
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    770
  • Tissues
    37
  • cDNA Data
    17
  • Literature Summary
    34
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000002944 Ensembl Gene Model | MGI Sequence Detail 107112 C57BL/6J ±  kb
    transcript ENSMUST00000170051 Ensembl | MGI Sequence Detail 3399 Not Applicable  
    polypeptide ENSMUSP00000133008 Ensembl | MGI Sequence Detail 472 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 27
      cDNA 18
      Primer pair 9
      Antibodies 1

      Microarray probesets 6
    Other
    Accession IDs
    less
    MGD-MRK-36478
    References
    more
    • Summaries
      All 491
      Developmental Gene Expression 34
      Diseases 2
      Gene Ontology 35
      Phenotypes 325
    • Earliest
      J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
    • Latest
      J:383108 Lin L, et al., A single-cell time-series atlas of endothelial cell embryonic development. Cell. 2026 Mar 5;189(5):1573-1590.e24
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/01/2026
    MGI 6.24     		The Jackson Laboratory