Shh+/Shhtm1Chg
Zic2Ku/Zic2+
involves: 129S1/Sv * 129X1/SvJ * BALB/cAnNCrl * C3H/HeH
|
no abnormal phenotype detected |
J:138862
|
Artm2Ska/Y
Shhtm2(cre/ERT2)Cjt/Shh+
involves: 129S6/SvEvTac * C57BL/6 * CBA
|
normal
reproductive system phenotype |
J:148515
|
Bmpr1atm2.1Bhr/Bmpr1atm2.1Bhr
Shhtm1(EGFP/cre)Cjt/?
involves: 129S7/SvEvBrd
|
preweaning lethality, complete penetrance |
J:166768
|
Ccd/Ccd+
ShhDsh/Shh+
involves: 101 * C3H * C57BL * C57BL/10Rl * SEC
|
abnormal clavicle morphology |
J:16170
|
|
abnormal cranium morphology |
J:16170
|
|
abnormal hindlimb morphology |
J:16170
|
|
abnormal humerus morphology |
J:16170
|
|
abnormal interparietal bone morphology |
J:16170
|
|
abnormal ischium morphology |
J:16170
|
|
abnormal maxilla morphology |
J:16170
|
|
abnormal neurocranium morphology |
J:16170
|
|
abnormal orbit morphology |
J:16170
|
|
abnormal pectoral girdle bone morphology |
J:16170
|
|
abnormal pelvic girdle bone morphology |
J:16170
|
|
abnormal pubis morphology |
J:16170
|
|
abnormal scapula morphology |
J:16170
|
|
abnormal temporal bone squamous part morphology |
J:16170
|
|
abnormal ventral tubercle of atlas morphology |
J:16170
|
|
abnormal vertebrae morphology |
J:16170
|
|
abnormal xiphoid process morphology |
J:16170
|
|
absent deltoid tuberosity |
J:16170
|
|
absent nasal bone |
J:16170
|
|
brachydactyly |
J:16170
|
|
fusion of atlas and odontoid process |
J:16170
|
|
occipital bone foramen |
J:16170
|
|
premature death |
J:16170
|
|
syndactyly |
J:16170
|
Chd7tm1.1Dmm/Chd7tm1.1Dmm
Gt(ROSA)26Sortm6(CAG-ZsGreen1)Hze/Gt(ROSA)26Sor+
Shhtm1(EGFP/cre)Cjt/Shh+
involves: 129S1/SvlmJ * 129S6/SvEvTac * C57BL/6J * SJL/J
|
normal
hearing/vestibular/ear phenotype |
J:310063
|
Ctnnb1tm1Mmt/Ctnnb1tm1Mmt
Shhtm1(EGFP/cre)Cjt/Shh+
involves: 129X1/SvJ
|
abnormal lung development |
J:204743
|
|
abnormal lung vasculature morphology |
J:204743
|
|
abnormal pulmonary artery morphology |
J:204743
|
|
abnormal pulmonary vein morphology |
J:204743
|
|
absent lungs |
J:204743
|
|
normal
cardiovascular system phenotype |
J:204743
|
|
tracheoesophageal fistula |
J:153098
|
Ctnnb1tm2Kem/Ctnnb1tm2Kem
Gt(ROSA)26Sortm1(Fgf8)Lma/Gt(ROSA)26Sor+
Shhtm1(EGFP/cre)Cjt/Shh+
involves: 129S1/Sv * 129X1/SvJ
|
abnormal reproductive system development |
J:223057
|
|
abnormal tail development |
J:223057
|
|
normal
reproductive system phenotype |
J:223057
|
Ctnnb1tm2Kem/Ctnnb1tm2Kem
Shhtm1(EGFP/cre)Cjt/Shh+
involves: 129S1/Sv * 129X1/SvJ
|
abnormal lung development |
J:153098
|
|
absent lung buds |
J:153098
|
|
absent lungs |
J:153098
|
Dicer1tm1Bdh/Dicer1+
Yy1tm2.1Yshi/Yy1+
Shhtm1(EGFP/cre)Cjt/Shh+
involves: 129 * 129S4/SvJae * C57BL/6
|
normal
respiratory system phenotype |
J:239777
|
Dicer1tm1Bdh/Dicer1tm1Bdh
Shhtm1(EGFP/cre)Cjt/Shh+
involves: 129
|
abnormal lung development |
J:106072
|
|
abnormal lung epithelium morphology |
J:106072
|
|
perinatal lethality, complete penetrance |
J:106072
|
|
small lung lobe |
J:106072
|
Dicer1tm1Mmk/Dicer1tm1Mmk
Fgf9tm1.1Fwan/Fgf9+
Shhtm1(EGFP/cre)Cjt/Shh+
involves: 129 * 129S4/SvJaeSor * C57BL/6J
|
normal
respiratory system phenotype |
J:224791
|
Dicer1tm1Mmk/Dicer1tm1Mmk
Fgf9tm1.1Fwan/Fgf9tm1.1Fwan
Shhtm1(EGFP/cre)Cjt/Shh+
involves: 129 * 129S4/SvJaeSor * C57BL/6J
|
normal
respiratory system phenotype |
J:224791
|
Dicer1tm1Mmk/Dicer1tm1Mmk
Shhtm1(EGFP/cre)Cjt/Shh+
involves: 129 * C57BL/6J
|
abnormal branching involved in lung morphogenesis |
J:224791
|
|
abnormal lung epithelium morphology |
J:224791
|
|
abnormal lung-associated mesenchyme development |
J:224791
|
|
enlarged lung |
J:224791
|
|
increased mesenchymal cell proliferation involved in lung development |
J:224791
|
|
lung cyst |
J:224791
|
Disp1icb/Disp1icb
Shhtm1Amc/Shhtm5Amc
Edil3Tg(Sox2-cre)1Amc/Edil3+
involves: 129/Sv * C57BL/6J * SWR
|
abnormal frontonasal prominence morphology |
J:94270
|
|
perinatal lethality, complete penetrance |
J:94270
|
Disp1icb/Disp1tm1Amc
Shhtm1(EGFP/cre)Cjt/Shh+
involves: 129X1/SvJ * C57BL/6J
|
oligodactyly |
J:92504
|
Disp1icb/Disp1tm1Amc
Shhtm1Amc/Shh+
involves: 129X1/SvJ * C57BL/6J
|
abnormal neuron specification |
J:92058
|
|
failure of heart looping |
J:92058
|
|
holoprosencephaly |
J:92058
|
|
proboscis |
J:92058
|
Disp1icb/Disp1tm2Amc
Shhtm1(EGFP/cre)Cjt/Shh+
involves: 129/Sv * C57BL/6J * SWR
|
abnormal facial morphology |
J:94270
|
|
abnormal nasal pit morphology |
J:94270
|
|
abnormal neuron differentiation |
J:94270
|
|
absent floor plate |
J:94270
|
|
absent parietal bone |
J:94270
|
|
absent premaxilla |
J:94270
|
|
neonatal lethality |
J:94270
|
Disp1tm1Pab/Disp1tm1Pab
Shhtm2Chg/Shh+
Edil3Tg(Sox2-cre)1Amc/Edil3+
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA
|
abnormal digit morphology |
J:109101
|
|
perinatal lethality, complete penetrance |
J:109101
|
|
preaxial polydactyly |
J:109101
|
Disp1tm2.1Amc/Disp1tm2.1Amc
Shhtm1Amc/Shh+
involves: 129/Sv * C57BL/6J * SWR
|
abnormal neuron differentiation |
J:94270
|
|
absent floor plate |
J:94270
|
Disp1tm2.1Amc/Disp1tm2Amc
Shhtm1(EGFP/cre)Cjt/Shh+
involves: 129/Sv * C57BL/6J * SWR
|
abnormal facial morphology |
J:94270
|
|
abnormal nasal pit morphology |
J:94270
|
|
abnormal neuron differentiation |
J:94270
|
|
abnormal parietal bone morphology |
J:94270
|
|
absent premaxilla |
J:94270
|
|
neonatal lethality |
J:94270
|
E2f4tm2.1Lees/E2f4tm2.1Lees
Shhtm1(EGFP/cre)Cjt/Shh+
involves: 129S4/SvJae * 129S4/SvJaeSor * C57BL/6
|
abnormal respiratory motile cilium morphology |
J:241925
|
Fgfr1tm1Jpa/Fgfr1tm1Jpa
Fgfr2tm1Dor/Fgfr2tm1Dor
Shhtm1(EGFP/cre)Cjt/Shh+
involves: 129S1/Sv * 129X1/SvJ
|
abnormal urethra urothelium morphology |
J:223057
|
|
normal
reproductive system phenotype |
J:223057
|
Fgfr1tm3.1Cxd/Fgfr1tm3.2Cxd
Shhtm1(EGFP/cre)Cjt/Shh+
involves: 129S6/SvEvTac
|
abnormal embryonic autopod plate morphology |
J:101736
|
|
oligodactyly |
J:101736
|
Fgfr1tm3.2Cxd/Fgfr1tm3.2Cxd
Shhtm1(EGFP/cre)Cjt/Shh+
involves: 129S6/SvEvTac
|
abnormal embryonic autopod plate morphology |
J:101736
|
|
oligodactyly |
J:101736
|
Fkbp8tm1Tili/Fkbp8tm1Tili
Shhtm1Chg/Shhtm1Chg
involves: C57BL/6
|
abnormal dorsal-ventral axis patterning |
J:89364
|
|
abnormal limb morphology |
J:89364
|
|
abnormal neural tube morphology |
J:89364
|
|
abnormal somite shape |
J:89364
|
|
absent notochord |
J:89364
|
|
decreased somite size |
J:89364
|
|
microphthalmia |
J:89364
|
Foxp1tm1.1Pwt/Foxp1tm1.1Pwt
Foxp4tm2.1Eem/Foxp4tm2.1Eem
Shhtm1(EGFP/cre)Cjt/Shh+
involves: 129S1/Sv * 129X1/SvJ * C57BL/6
|
abnormal respiratory system development |
J:185603
|
|
decreased club cell number |
J:185603
|
|
neonatal lethality, complete penetrance |
J:185603
|
|
respiratory distress |
J:185603
|
Foxp4tm2.1Eem/Foxp4tm2.1Eem
Shhtm1(EGFP/cre)Cjt/Shh+
involves: 129S1/Sv * 129X1/SvJ * C57BL/6
|
normal
mortality/aging |
J:185603
|
Gas1tm1Fan/Gas1tm1Fan
Shhtm1Chg/Shh+
involves: 129S1/Sv * 129X1/SvJ * C57BL/6
|
abnormal basisphenoid bone morphology |
J:122159
|
|
abnormal craniofacial bone morphology |
J:122159
|
|
abnormal incisor morphology |
J:122159
|
|
abnormal lower incisor morphology |
J:122159
|
|
abnormal mandible morphology |
J:122159
|
|
abnormal Meckel's cartilage morphology |
J:122159
|
|
abnormal middle ear morphology |
J:122159
|
|
abnormal molar morphology |
J:122159
|
|
abnormal nasal capsule morphology |
J:122159
|
|
abnormal neurocranium morphology |
J:122159
|
|
abnormal premaxilla morphology |
J:122159
|
|
abnormal stapes morphology |
J:122159
|
|
abnormal temporal bone morphology |
J:122159
|
|
absent gonial bone |
J:122159
|
|
absent incus |
J:122159
|
|
absent malleus |
J:122159
|
|
absent mandibular symphysis |
J:122159
|
|
absent tympanic ring |
J:122159
|
|
alisphenoid bone hypoplasia |
J:122159
|
|
cleft secondary palate |
J:122159
|
|
holoprosencephaly |
J:122159
|
|
perinatal lethality, complete penetrance |
J:122159
|
|
premature coronal suture closure |
J:122159
|
|
premaxilla hypoplasia |
J:122159
|
|
short Meckel's cartilage |
J:122159
|
|
single external naris |
J:122159
|
|
small cranium |
J:122159
|
|
synostosis |
J:122159
|
Gas1tm1Fan/Gas1tm1Fan
Shhtm1Chg/Shhtm1Chg
involves: 129S1/Sv * 129X1/SvJ * C57BL/6
|
abnormal craniofacial morphology |
J:122159
|
|
embryonic lethality, complete penetrance |
J:122159
|
Gas1tm2Fan/Gas1+
Shhtm1Chg/Shh+
involves: 129S1/Sv * 129X1/SvJ * C57BL/6J
|
increased neuronal precursor cell number |
J:121553
|
Gas1tm2Fan/Gas1tm2Fan
Shhtm1Chg/Shh+
involves: 129/Sv * 129S1/Sv * 129X1/SvJ * C57BL/6J
|
holoprosencephaly |
J:121554
|
|
oligodactyly |
J:121554
|
|
single external naris |
J:121554
|
Gas1tm2Fan/Gas1tm2Fan
Shhtm1Chg/Shh+
involves: 129S1/Sv * 129X1/SvJ * C57BL/6J
|
abnormal craniofacial morphology |
J:121553
|
|
abnormal floor plate morphology |
J:121553
|
|
abnormal innervation |
J:121553
|
|
abnormal intervertebral disk morphology |
J:121553
|
|
abnormal nose morphology |
J:121553
|
|
abnormal vertebral body morphology |
J:121553
|
|
decreased fetal size |
J:121553
|
|
decreased neuronal precursor cell number |
J:121553
|
|
forelimb oligodactyly |
J:121553
|
|
short mandible |
J:121553
|
Gas1tm2Fan/Gas1tm2Fan
Shhtm1Chg/Shhtm1Chg
involves: 129/Sv * 129S1/Sv * 129X1/SvJ * C57BL/6J
|
abnormal embryo turning |
J:121554
|
|
abnormal heart tube morphology |
J:121554
|
|
abnormal rostral-caudal body axis extension |
J:121554
|
|
cardiac edema |
J:121554
|
|
decreased embryo size |
J:121554
|
|
embryonic growth arrest |
J:121554
|
|
embryonic lethality during organogenesis, complete penetrance |
J:121554
|
|
enlarged pericardium |
J:121554
|
Gata6tm2.1Sad/Gata6tm2.1Sad
Shhtm2Amc/Shhtm2Amc
Tg(Prrx1-cre)1Cjt/0
involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * SJL/J
|
hindlimb oligodactyly |
J:205405
|
Gli1tm1Alj/Gli1tm1Alj
Tg(Shh)#Dje/0
involves: 129S1/Sv * 129X1/SvJ * Swiss Webster
|
abnormal cell proliferation |
J:94461
|
|
abnormal cerebellar granule layer morphology |
J:94461
|
|
abnormal cerebellar lobule formation |
J:94461
|
|
abnormal cerebellum external granule cell layer morphology |
J:94461
|
|
abnormal cerebellum morphology |
J:94461
|
Gli2tm1Blnw/Gli2tm1Blnw
Shhtm1Chg/Shhtm1Chg
involves: 129S1/Sv * 129X1/SvJ * C57BL/6
|
normal
cellular phenotype |
J:145182
|
|
normal
nervous system phenotype |
J:145182
|
Gli2tm2.1Alj/Gli2+
Shhtm1Chg/Shhtm1Chg
either: (involves: 129) or (involves: 129 * Black Swiss)
|
abnormal spinal cord morphology |
J:73074
|
|
abnormal telencephalon development |
J:73074
|
|
decreased embryo size |
J:73074
|
Gli2tm2.1Alj/Gli2tm2.1Alj
Shhtm1Chg/Shhtm1Chg
either: (involves: 129) or (involves: 129 * Black Swiss)
|
abnormal spinal cord interneuron morphology |
J:73074
|
|
absent floor plate |
J:73074
|
|
cyclopia |
J:73074
|
|
decreased motor neuron number |
J:73074
|
Gli2tm2.1Alj/Gli2tm3.1(Gli1)Alj
Shhtm1Chg/Shhtm1Chg
either: (involves: 129) or (involves: 129 * Black Swiss)
|
abnormal diencephalon morphology |
J:73074
|
|
abnormal ventral interneuron 3 morphology |
J:73074
|
|
absent floor plate |
J:73074
|
|
decreased motor neuron number |
J:73074
|
|
megacephaly |
J:73074
|
Gli3tm2Blnw/Gli3+
Shhtm1Chg/Shhtm1Chg
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * FVB/N
|
abnormal autopod morphology |
J:121609
|
|
abnormal digit morphology |
J:121609
|
|
abnormal limb morphology |
J:121609
|
|
abnormal phalanx morphology |
J:121609
|
|
absent tibia |
J:121609
|
|
polydactyly |
J:121609
|
|
short tibia |
J:121609
|
|
synostosis |
J:121609
|
Gt(ROSA)26Sortm1(CAG-Bmpr1a)Que/Gt(ROSA)26Sor+
Shhtm1(EGFP/cre)Cjt/?
Not Specified
|
abnormal esophageal epithelium morphology |
J:166768
|
|
abnormal forestomach morphology |
J:166768
|
|
preweaning lethality, complete penetrance |
J:166768
|
Gt(ROSA)26Sortm1(Fgf8)Lma/Gt(ROSA)26Sor+
Shhtm2(cre/ERT2)Cjt/Shh+
involves: 129S6/SvEvTac
|
abnormal genital tubercle morphology |
J:223057
|
|
abnormal reproductive system physiology |
J:223057
|
Gt(ROSA)26Sortm1(Fgf8)Lma/Gt(ROSA)26Sor+
Shhtm2(cre/ERT2)Cjt/Shhtm2(cre/ERT2)Cjt
involves: 129S6/SvEvTac
|
abnormal genital tubercle morphology |
J:223057
|
Gt(ROSA)26Sortm1(Fgf8)Lma/Gt(ROSA)26Sor+
Shhtm2(cre/ERT2)Cjt/Shhtm2(cre/ERT2)Cjt
Tg(Msx2-cre)5Rem/0
involves: 129S6/SvEvTac * C57BL/6 * CBA
|
abnormal limb development |
J:223057
|
Gt(ROSA)26Sortm1(Grem1)Svok/Gt(ROSA)26Sor+
Shhtm1(EGFP/cre)Cjt/0
involves: 129S1/Sv
|
polyphalangy |
J:214075
|
|
postaxial polydactyly |
J:214075
|
|
preaxial polydactyly |
J:214075
|
Gt(ROSA)26Sortm1(Notch1)Dam/Gt(ROSA)26Sor+
Shhtm2(cre/ERT2)Cjt/Shh+
involves: 129S4/SvJaeSor * 129S6/SvEvTac
|
normal
vision/eye phenotype |
J:118372
|
Gt(ROSA)26Sortm1(Smo/EYFP)Amc/Gt(ROSA)26Sortm1(Smo/EYFP)Amc
Shhtm2(cre/ERT2)Cjt/Shh+
involves: 129S6/SvEvTac * 129X1/SvJ
|
normal
neoplasm |
J:139574
|
Gt(ROSA)26Sortm1(tetO-Sox9)Msan/Gt(ROSA)26Sortm1(rtTA,EGFP)Nagy
Shhtm1(EGFP/cre)Cjt/Shh+
involves: 129S1/Sv * 129X1/SvJ
|
abnormal lung morphology |
J:202984
|
|
lung cyst |
J:202984
|
|
small lung |
J:202984
|
Gt(ROSA)26Sortm2(Sp8)Lma/Gt(ROSA)26Sor+
Shhtm1(EGFP/cre)Cjt/Shh+
Not Specified
|
normal
limbs/digits/tail phenotype |
J:223057
|
Gt(ROSA)26Sortm4(CAG-lacZ,-EGFP)Dym/Gt(ROSA)26Sor+
Shhtm1(EGFP/cre)Cjt/Shh+
involves: C57BL/6
|
abnormal skin morphology |
J:132568
|
|
thin epidermis |
J:132568
|
Gt(ROSA)26Sortm5(Etv4/en,-GFP)Amc/Gt(ROSA)26Sor+
Shhtm1Amc/Shhtm2Amc
Tg(Prrx1-cre)1Cjt/0
involves: 129 * C57BL/6 * CBA * SJL/J * Swiss Webster
|
abnormal digit morphology |
J:149478
|
HhatTg(TFAP2A-cre)1Will/Hhat+
Shhtm1Chg/Shh+
involves: 129S1/Sv * 129X1/SvJ
|
abnormal craniofacial morphology |
J:190013
|
Ift88tm1Bky/Ift88tm1Bky
Shhtm1(EGFP/cre)Cjt/Shh+
involves: 129P2/OlaHsd
|
abnormal palatal rugae morphology |
J:281425
|
Ift122sopb/Ift122sopb
Shhtm1Chg/Shhtm1Chg
involves: 129S1/Sv * 129X1/SvJ * C3HeB/FeJ * C57BL/6J
|
abnormal neural tube morphology |
J:168317
|
|
exencephaly |
J:168317
|
|
open neural tube |
J:168317
|
Ihhtm1Amc/Ihhtm1Amc
Shhtm1Amc/Shhtm1Amc
involves: 129/Sv * C57BL/6J * CBA/J
|
embryonic growth arrest |
J:62158
|
Ihhtm1Amc/Ihhtm1Amc
Shhtm1Chg/Shhtm1Chg
involves: 129S1/Sv * 129X1/SvJ * C57BL/6
|
abnormal visceral yolk sac mesenchyme morphology |
J:128367
|
|
abnormal visceral yolk sac morphology |
J:128367
|
|
absent vitelline blood vessels |
J:128367
|
|
failure of initiation of embryo turning |
J:128367
|
Krastm4Tyj/Kras+
Trp53tm1Brn/Trp53tm1Brn
Shhtm2(cre/ERT2)Cjt/Shh+
involves: 129P2/OlaHsd * 129S4/SvJae * 129S6/SvEvTac
|
normal
integument phenotype |
J:172048
|
Krastm4Tyj/Kras+
Shhtm2(cre/ERT2)Cjt/Shh+
involves: 129S4/SvJae * 129S6/SvEvTac
|
normal
integument phenotype |
J:172048
|
Ndst1tm1.1Grob/Ndst1+
Shhtm1Chg/Shh+
involves: 129S1/Sv * 129X1/SvJ * C57BL/6
|
abnormal eye development |
J:100425
|
|
abnormal maxillary prominence morphology |
J:100425
|
|
absent olfactory epithelium |
J:100425
|
|
absent tongue |
J:100425
|
|
aphakia |
J:100425
|
|
frontonasal prominence hypoplasia |
J:100425
|
|
mandible hypoplasia |
J:100425
|
|
microphthalmia |
J:100425
|
|
small snout |
J:100425
|
Ndst1tm1.1Grob/Ndst1tm1.1Grob
Shhtm1Chg/Shh+
involves: 129S1/Sv * 129X1/SvJ * C57BL/6
|
abnormal forebrain morphology |
J:100425
|
|
abnormal maxillary prominence morphology |
J:100425
|
|
abnormal midbrain morphology |
J:100425
|
|
frontonasal prominence hypoplasia |
J:100425
|
|
prenatal lethality |
J:100425
|
Nr5a1tm1.1Hain/Nr5a1tm1.1Hain
Shhtm1Amc/Shh+
involves: 129S1/Sv * 129X1/SvJ
|
abnormal aldosterone level |
J:175843
|
Pofut1tm2Pst/Pofut1tm1Pst
Shhtm2(cre/ERT2)Cjt/Shh+
involves: 129/Sv * 129S6/SvEvTac * C57BL/6J * SJL
|
abnormal bronchiole epithelium morphology |
J:150051
|
|
abnormal respiratory epithelium morphology |
J:150051
|
|
absent club cells |
J:150051
|
|
decreased birth body size |
J:150051
|
|
decreased body size |
J:150051
|
|
increased solitary pulmonary neuroendocrine cell number |
J:150051
|
|
lung inflammation |
J:150051
|
|
postnatal lethality, incomplete penetrance |
J:150051
|
|
premature death |
J:150051
|
|
normal
respiratory system phenotype |
J:150051
|
Ptch1tm1Mps/Ptch1+
Tg(Shh)#Dje/0
involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * Swiss Webster
|
abnormal cerebellar foliation |
J:108507
|
|
abnormal cerebellum development |
J:108507
|
|
abnormal cerebellum morphology |
J:108507
|
Ptch1tm1Mps/Ptch1+
Shhtm6Amc/Shhtm6Amc
involves: 129S1/Sv * 129X1/SvJ
|
no abnormal phenotype detected |
J:132152
|
Rbpjtm1Hon/Rbpjtm1.1Hon
Shhtm2(cre/ERT2)Cjt/Shh+
involves: 129P2/OlaHsd * 129S6/SvEvTac
|
abnormal respiratory epithelium morphology |
J:150051
|
|
absent club cells |
J:150051
|
Robo1tm1Matl/Robo1tm1Matl
Robo2tm1Rilm/Robo2tm1Rilm
Shhtm1(EGFP/cre)Cjt/Shh+
involves: 129
|
no abnormal phenotype detected |
J:193400
|
Rr26tm1Svok/Rr26tm1Svok
Shhtm1Chg/Shh+
involves: 129S1/Sv * 129X1/SvJ
|
normal
limbs/digits/tail phenotype |
J:207959
|
Rr29tm1.1Bobh/Rr29+
Shhtm1Chg/Shh+
involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ
|
abnormal limb morphology |
J:208849
|
|
oligodactyly |
J:208849
|
Rr45tm1.1Tshir/Rr45+
Shhtm1Chg/Shh+
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA/JNCrlj
|
abnormal arytenoid cartilage morphology |
J:148018
|
|
epiglottis hypoplasia |
J:148018
|
Rr115em1Bobh/Rr115+
Shhtm1Chg/Shh+
involves: 129S1/Sv * 129X1/SvJ * C57BL/6J
|
abnormal adenohypophysis development |
J:306254
|
|
abnormal hypothalamus morphology |
J:306254
|
|
abnormal magnocellular neurosecretory cell morphology |
J:306254
|
|
abnormal maxilla morphology |
J:306254
|
|
abnormal nasal cavity morphology |
J:306254
|
|
abnormal neurohypophysis development |
J:306254
|
|
abnormal parvocellular neurosecretory cell morphology |
J:306254
|
|
abnormal pterygoid bone morphology |
J:306254
|
|
abnormal Rathke's pouch development |
J:306254
|
|
basisphenoid bone hypoplasia |
J:306254
|
|
ectopic neurohypophysis |
J:306254
|
|
perinatal lethality, complete penetrance |
J:306254
|
|
round head |
J:306254
|
|
vomer bone hypoplasia |
J:306254
|
Rr117tm1.1Dje/Rr117+
Shhtm1Amc/Shh+
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CD-1 * FVB/N
|
normal
behavior/neurological phenotype |
J:170540
|
|
normal
homeostasis/metabolism phenotype |
J:170540
|
|
postnatal lethality, incomplete penetrance |
J:170540
|
|
slow postnatal weight gain |
J:170540
|
ShhDsh/Shh+
B10Rl.Cg-ShhDsh
|
abnormal cartilage development |
J:97323
|
|
abnormal cartilage morphology |
J:97323
|
|
abnormal chondrocyte differentiation |
J:97323
|
|
abnormal cranium morphology |
J:16170
|
|
abnormal frontal bone morphology |
J:14105,
J:16170
|
|
abnormal hindlimb morphology |
J:16170
|
|
abnormal joint morphology |
J:97323
|
|
abnormal maxilla morphology |
J:16170
|
|
abnormal neurocranium morphology |
J:16170
|
|
abnormal phalanx morphology |
J:14105,
J:97323
|
|
abnormal rib morphology |
J:14105,
J:16170
|
|
abnormal vertebrae morphology |
J:16170
|
|
brachydactyly |
J:14105,
J:16170,
J:97323
|
|
brachyphalangia |
J:14105,
J:97323
|
|
cervical vertebral fusion |
J:14105
|
|
decreased chondrocyte proliferation |
J:97323
|
|
fused joints |
J:97323
|
|
fusion of atlas and odontoid process |
J:16170
|
|
occipital bone foramen |
J:16170
|
|
short metacarpal bones |
J:97323
|
|
syndactyly |
J:14105,
J:16170,
J:97323
|
|
thin interparietal bone |
J:16170
|
ShhDsh/Shh+
involves: 101 * C3H * C57BL * SEC
|
brachydactyly |
J:14105
|
ShhDsh/ShhDsh
B10Rl.Cg-ShhDsh
|
decreased embryo size |
J:16170
|
|
prenatal lethality, incomplete penetrance |
J:16170
|
|
short limbs |
J:16170
|
ShhDsh/ShhDsh
involves: 101 * C3H * C57BL * SEC
|
abnormal ear morphology |
J:14105,
J:16170
|
|
abnormal embryo size |
J:14105,
J:16170
|
|
absent external female genitalia |
J:14105,
J:16170
|
|
absent external male genitalia |
J:14105,
J:16170
|
|
absent mouth |
J:14105,
J:16170
|
|
anophthalmia |
J:14105
|
|
brachydactyly |
J:16170
|
|
cyclopia |
J:16170
|
|
embryonic lethality during organogenesis, incomplete penetrance |
J:14105,
J:16170
|
|
microcephaly |
J:14105,
J:16170
|
|
neonatal lethality, complete penetrance |
J:16170
|
|
short limbs |
J:14105,
J:16170
|
ShhDsh/Shhtm1Chg
involves: 101 * 129S1/Sv * 129X1/SvJ * C3H * C57BL/10Rl
|
abnormal dorsal-ventral axis patterning |
J:97323
|
|
abnormal limb morphology |
J:97323
|
Shhtm1(EGFP/cre)Cjt/Shh+
Sox17tm1Ysk/Sox17+
involves: 129S1/Sv * C57BL/6
|
abnormal gallbladder smooth muscle morphology |
J:241569
|
Shhtm1(EGFP/cre)Cjt/Shh+
Sox9tm2Crm/Sox9tm2Crm
B6.Cg-Shhtm1(EGFP/cre)Cjt Sox9tm2Crm
|
abnormal primitive urogenital sinus morphology |
J:281428
|
Shhtm1Amc/Shhtm1Amc
Tg(SFTPC-rtTA)5Jaw/0
Tg(tetO-Shh)1Jaw/0
involves: FVB/N
|
abnormal lung lobe morphology |
J:91723
|
|
absent tracheal cartilage rings |
J:91723
|
|
neonatal lethality, complete penetrance |
J:91723
|
Shhtm1Chg/Shh+
Sulf1Gt(XM190)Byg/Sulf1Gt(XM190)Byg
Sulf2Gt(PST111)Byg/Sulf2Gt(PST111)Byg
involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6 * C57BL/10
|
abnormal craniofacial morphology |
J:130163
|
|
absent mandible |
J:130163
|
|
anophthalmia |
J:130163
|
|
microphthalmia |
J:130163
|
|
short mandible |
J:130163
|
Shhtm1Chg/Shh+
Vps25m1Lis/Vps25m1Lis
involves: 129S1/Sv * 129X1/SvJ * C3H * C57BL/6J
|
abnormal outer ear morphology |
J:223082
|
|
mandible hypoplasia |
J:223082
|
|
polydactyly |
J:223082
|
|
short snout |
J:223082
|
Shhtm1Chg/Shhtm1Chg
Tg(Prrx1-Sox9,-lacZ)1Haak/0
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA/2
|
abnormal limb bud morphology |
J:121946
|
Shhtm1Chg/Shhtm1Chg
Tmem107schlei/Tmem107schlei
involves: 129S1/Sv * 129X1/SvJ * C3HeB/FeJ * C57BL/6J
|
abnormal floor plate morphology |
J:186552
|
|
exencephaly |
J:186552
|
|
normal
limbs/digits/tail phenotype |
J:186552
|
|
oligodactyly |
J:186552
|
Shhtm1Chg/Shhtm1Chg
Tulp3hhkr/Tulp3hhkr
involves: 129S1/Sv * 129X1/SvJ * C3H/HeH * C57BL/6
|
abnormal neural tube morphology |
J:147584
|
|
edema |
J:147584
|
|
exencephaly |
J:147584
|
|
oligodactyly |
J:147584
|
|
spina bifida |
J:147584
|
Shhtm1Chg/Shhtm1Chg
Zic2Ku/Zic2Ku
involves: 129S1/Sv * 129X1/SvJ * BALB/cAnNCrl * C3H/HeH
|
abnormal forebrain morphology |
J:138862
|
|
abnormal heart morphology |
J:138862
|
|
decreased embryo size |
J:138862
|
|
failure of initiation of embryo turning |
J:138862
|
Six3tm3.1Gco/Six3+
Shhtm1Chg/Shh+
involves: 129S1/Sv * 129X1/SvJ * C57BL/6
|
abnormal cerebral hemisphere morphology |
J:140315
|
|
abnormal medial nasal prominence morphology |
J:140315
|
|
abnormal optic stalk morphology |
J:140315
|
|
abnormal palatal shelf fusion at midline |
J:140315
|
|
abnormal telencephalon morphology |
J:140315
|
|
absent corpus callosum |
J:140315
|
|
absent nasal septum |
J:140315
|
|
absent philtrum |
J:140315
|
|
holoprosencephaly |
J:140315
|
|
microcephaly |
J:140315
|
|
ocular hypotelorism |
J:140315
|
|
olfactory bulb hypoplasia |
J:140315
|
Sox9tm1Gsr/Sox9tm1Gsr
Shhtm1(EGFP/cre)Cjt/Shh+
involves: 129P2/OlaHsd
|
abnormal branching involved in lung morphogenesis |
J:202984
|
|
abnormal cell differentiation |
J:202984
|
|
abnormal lung epithelium morphology |
J:202984
|
|
decreased cell migration |
J:202984
|
|
decreased cell proliferation |
J:202984
|
|
lung cyst |
J:202984
|
|
perinatal lethality, incomplete penetrance |
J:202984
|
|
postnatal lethality, complete penetrance |
J:202984
|
|
respiratory distress |
J:202984
|
|
small lung |
J:202984
|
Sp8tm1Smb/Sp8tm1Smb
Shhtm1(EGFP/cre)Cjt/Shh+
involves: 129S1/Sv * 129X1/SvJ
|
abnormal craniofacial development |
J:200761
|
|
normal
craniofacial phenotype |
J:200761
|
|
ocular hypertelorism |
J:200761
|
Tctn1Gt(KST296)Byg/Tctn1Gt(KST296)Byg
Shhtm1Chg/Shhtm1Chg
involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6
|
increased forebrain size |
J:103820
|
Tg(UAS-Shh)1Rth/0
Tg(Wnt1-GAL4)1Rth/0
involves: C57BL/6J * CBA/J
|
abnormal blood vessel morphology |
J:57948
|
|
abnormal epaxial muscle morphology |
J:57948
|
|
abnormal midbrain morphology |
J:57948
|
|
abnormal neurocranium morphology |
J:57948
|
|
abnormal spinal cord morphology |
J:57948
|
|
absent vertebral arch |
J:57948
|
|
hemorrhage |
J:57948
|
|
hydromyelia |
J:57948
|
|
increased cell proliferation |
J:57948
|
|
increased spinal cord size |
J:57948
|
|
midbrain hyperplasia |
J:57948
|
Wnt1tm1.1Mze/Wnt1tm1.1Mze
Gt(ROSA)26Sortm14(CAG-tdTomato)Hze/Gt(ROSA)26Sor+
Shhtm1(EGFP/cre)Cjt/Shh+
involves: 129S6/SvEvTac * C57BL/6N
|
abnormal midbrain morphology |
J:194842
|
|
decreased neuron number |
J:194842
|
|
premature neuronal precursor differentiation |
J:194842
|
Yy1tm2.1Yshi/Yy1tm2.1Yshi
Shhtm1(EGFP/cre)Cjt/Shh+
involves: 129S4/SvJae * C57BL/6J
|
abnormal airway basal cell morphology |
J:239777
|
|
abnormal branching involved in lung morphogenesis |
J:239777
|
|
abnormal lung development |
J:239777
|
|
abnormal lung epithelium morphology |
J:239777
|
|
abnormal lung morphology |
J:239777
|
|
abnormal lung-associated mesenchyme development |
J:239777
|
|
abnormal respiratory epithelium physiology |
J:239777
|
|
abnormal trachea morphology |
J:239777
|
|
abnormal tracheal cartilage morphology |
J:239777
|
|
abnormal tracheal ciliated epithelium morphology |
J:239777
|
|
decreased club cell number |
J:239777
|
|
decreased respiratory mucosa goblet cell number |
J:239777
|
|
impaired myofibroblast differentiation |
J:239777
|
|
increased lung apoptosis |
J:239777
|
|
left pulmonary isomerism |
J:239777
|
|
lung cyst |
J:239777
|
|
neonatal lethality, complete penetrance |
J:239777
|
|
respiratory failure |
J:239777
|
|
trachea stenosis |
J:239777
|
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