Sox9^tm1Gsr
Targeted Allele Detail

Summary

• Symbol: Sox9^tm1Gsr
• Name: SRY (sex determining region Y)-box 9; targeted mutation 1, Gerd Scherer
• MGI ID: MGI:2385468
• Synonyms: Sox9^flox, Sox9-flox
• Gene: Sox9 Location: Chr11:112673050-112678586 bp, + strand Genetic Position: Chr11, 77.27 cM
• Alliance: Sox9^tm1Gsr page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:75124
• Parent Cell Line: E14.1 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A region containing exons 2 and 3 remains flanked by loxP sites following cre recombinase excision of a loxP-flanked neo cassette from Sox9^tm2Gsr. (J:75124)

Disease models

Expression

In Mice Carrying this Mutation:	238 assay results 5 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	25 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Sox9 Mutation: 32 strains or lines available

References

• Original: J:75124 Kist R, et al., Conditional inactivation of Sox9: a mouse model for campomelic dysplasia. Genesis. 2002 Feb;32(2):121-3
• All: 58 reference(s)