Gt(ROSA)26Sor^{tm1(Grem1)Svok}
Targeted Allele Detail

Summary

• Symbol: Gt(ROSA)26Sor^{tm1(Grem1)Svok}
• Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Steven Vokes
• MGI ID: MGI:5561086
• Synonyms: Gremlin, RG, Rosa^Gremlin, Tg(Rr26-lacZ)GremSvok
• Gene: Gt(ROSA)26Sor Location: Chr6:113044389-113054205 bp, - strand Genetic Position: Chr6, 52.73 cM
• Alliance: Gt(ROSA)26Sor^{tm1(Grem1)Svok} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:214075
• Parent Cell Line: CJ7 (ES Cell)
• Strain of Origin: 129S1/Sv-Oca2⁺ Tyr⁺ Kitl⁺

Mutation description

• Allele Type: Targeted (Conditional ready, Inserted expressed sequence)
• Mutation: Insertion
• Gt(ROSA)26Sor^{tm1(Grem1)Svok} expresses 1 gene
  Knock-in expresses:
  

  Organism	Expressed Gene	Note
  mouse	Grem1 (MGI:1344337)

• Mutation details: The targeting construct introduced into the locus a mouse Grem1 cDNA, a loxP-flanked cassette, PGK-NEO selection cassette, and a tpA transcriptional stop sequence. (J:210585, J:214075)

Expression

In Structures Affected by this Mutation:

9 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Gt(ROSA)26Sor Mutation: 942 strains or lines available

References

• Original: J:210585 Vokes SA, Direct data submission for cre-inducible transgene expressing Grem1 under the control of the Rosa26 promoter. MGI Direct Data Submission. 2014
• All: 3 reference(s)