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All mouse models of lymphatic system disease with phenotypic similarity to the human disease
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| Disease Term | Allelic Composition | Genetic Background | Reference | Phenotypes | ||||
  | B-cell lymphoma |
\Ezh2tm1.1Nesh/\Ezh2+ \Cd19tm1(cre)Cgn/\Cd19+ |
involves: 129 * 129P2/OlaHsd * C57BL/6 | J:239472 | View | |||
| Burkitt lymphoma | \Ightm1(Myc)Janz/\Igh+ | involves: 129X1/SvJ * C57BL/6 | J:96785 | View | ||||
| Burkitt lymphoma | \Myctm1Lbox/\Myc+ | involves: 129S1/Sv * 129X1/SvJ * FVB/N | J:97900 | View | ||||
| Burkitt lymphoma | \Myctm1Lbox/\Myctm1Lbox | involves: 129S1/Sv * 129X1/SvJ * FVB/N | J:97900 | View | ||||
| Burkitt lymphoma | \Tg(IghMyc)22Bri/0 | involves: C57BL/6 * SJL | J:78177, J:186117 | View | ||||
| familial hemophagocytic lymphohistiocytosis 2 | \Prf1tm1Sdz/\Prf1tm1Sdz | C57BL/6-Prf1tm1Sdz/J | J:92260, J:193137 | View | ||||
| familial hemophagocytic lymphohistiocytosis 3 | \Unc13dJinx/\Unc13dJinx | C57BL/6J-Unc13dJinx/Mmucd | J:119974 | View | ||||
| familial hemophagocytic lymphohistiocytosis 4 | \Stx11tm1.2Ics/\Stx11tm1.2Ics | involves: C57BL/6NTac | J:193137 | View | ||||
| | central conducting lymphatic anomaly | \Mdficem1Nlh/\Mdficem2Nlh | C57BL/6J-Mdficem1Nlh/Mdficem2Nlh | J:326462 | View | |||
| diffuse large B-cell lymphoma | \Smurf2Gt(RRA098)Byg/\Smurf2Gt(RRA098)Byg | involves: 129P2/OlaHsd * C57BL/6 | J:245679 | View | ||||
| diffuse large B-cell lymphoma | \Trp53tm1.2Awbr/\Trp53tm1.2Awbr | involves: C57BL/6 | J:173271 | View | ||||
| diffuse large B-cell lymphoma |
\Trp53tm1Tyj/\Trp53tm1Tyj \Tg(Ly6e-MALT1)#Isg/0 |
involves: 129S2/SvPas * C57BL/6 * CBA | J:185590 | View | ||||
| follicular lymphoma | \Rarres1tm1.2Mhl/\Rarres1+ | involves: 129S1/SvImJ * C57BL/6 * FVB/N * NIH Black Swiss | J:324270 | View | ||||
| follicular lymphoma | \Rarres1tm1.2Mhl/\Rarres1tm1.2Mhl | involves: 129S1/SvImJ * C57BL/6 * FVB/N * NIH Black Swiss | J:324270 | View | ||||
| follicular lymphoma | \Rarres1tm1d(KOMP)Wtsi/\Rarres1+ | involves: C57BL/6N | J:324270 | View | ||||
| hemophagocytic lymphohistiocytosis | \Elp1Gt(BGB184)Byg/\Elp1Gt(BGB184)Byg | B6.129P2-Gt(BGB184)Byg | J:145561 | View | ||||
| hemophagocytic lymphohistiocytosis | \Rab27aash/\Rab27aash | B6.C3Sn-Rab27aash | J:193137 | View | ||||
| hereditary lymphedema | \Flt4Chy/\Flt4+ | involves: C3H | J:72387 | View | ||||
| hereditary lymphedema | \Vegfctm1Ali/\Vegfc+ | involves: 129S1/Sv * 129X1/SvJ * ICR | J:209628 | View | ||||
| Langerhans-cell histiocytosis |
\Braftm1Mmcm/\Braftm1Mmcm \Cd207tm2.1(cre)Bjec/\Cd207+ |
involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6 | J:211690 | View | ||||
| Langerhans-cell histiocytosis |
\Braftm1Mmcm/\Braftm1Mmcm \Tg(Itgax-cre)1-1Reiz/0 |
involves: 129P2/OlaHsd * C57BL/6 * CBA | J:211690 | View | ||||
| lymphatic system disease | \Lgmntm1Ihn/\Lgmntm1Ihn | involves: 129P2/OlaHsd * C57BL/6 | J:143886 | View | ||||
| lymphoma |
\Gt(ROSA)26Sortm1(tTA,tetO-Mir155)Fjsl/\Gt(ROSA)26Sor+ \Tg(Nes-cre)1Wmz/0 |
involves: 129 * C57BL/6 * FVB/N * SJL/J | J:185598 | View | ||||
| lymphoma | \Tg(H2-K-Hmga1)#Lmsr/0 | involves: C57BL/6 * SJL | J:90252 | View | ||||
| malignant histiocytic disease | \Rcbtb2tm1.1Xyw/\Rcbtb2+ | involves: C57BL/6 * CBA | J:282928 | View | ||||
| malignant histiocytic disease | \Rcbtb2tm1.1Xyw/\Rcbtb2tm1.1Xyw | involves: C57BL/6 * CBA | J:282928 | View | ||||
| non-Hodgkin lymphoma | \Mtss1Gt(CSC156)Byg/\Mtss1Gt(CSC156)Byg | B6.129P2-Mtss1Gt(CSC156)Byg | J:186118 | View | ||||
| non-Hodgkin lymphoma | \S1pr2tm1Ajml/\S1pr2tm1Ajml | 129S5/SvEvBrd-S1pr2tm1Ajml | J:154439 | View | ||||
| non-Hodgkin lymphoma | \S1pr2tm1Ajml/\S1pr2tm1Ajml | involves: 129S5/SvEvBrd * C57BL/6 | J:154439 | View | ||||
| peripheral T-cell lymphoma | \Rc3h1san/\Rc3h1+ | involves: C57BL/6JSfdAnu | J:189087 | View | ||||
| T-cell acute lymphoblastic leukemia |
\Nbnem7Jpt/\Nbntm2Zqw \Tg(VAV1-cre)1Graf/0 |
involves: 129P2/OlaHsd | J:277750 | View | ||||
| T-cell acute lymphoblastic leukemia | \Tg(H2-K-Hmga1)#Lmsr/0 | involves: C57BL/6 * SJL | J:90252 | View | ||||
| T-cell adult acute lymphocytic leukemia |
\Gt(ROSA)26Sortm18(Zeb2)Jhai/\Gt(ROSA)26Sortm18(Zeb2)Jhai \Tg(Cd4-cre)1Cwi/0 |
involves: C57BL/6 * CD-1 * DBA/2 | J:263520 | View | ||||
| T-cell adult acute lymphocytic leukemia |
\Gt(ROSA)26Sortm18(Zeb2)Jhai/\Gt(ROSA)26Sortm18(Zeb2)Jhai \Tg(Tek-cre)1Ywa/0 |
involves: C57BL/6 * CD-1 * SJL | J:263520 | View | ||||
| T-cell adult acute lymphocytic leukemia | \Tg(Lck-Tax)53Hall/0 | involves: C57BL/6 | J:129531, J:214623 | View | ||||
| Transgenes and Other Mutations | Burkitt lymphoma | \Tg(IGL-MYC)3Hm/0 | C57BL/6N-Tg(IGL-MYC)3Hm/Nci | J:65245 | View | |||
| chronic lymphocytic leukemia | \Del(14Trim13-Dleu2)4Rdf/\Del(14Trim13-Dleu2)4Rdf | involves: 129S1/Sv * 129S4/SvJaeSor * C57BL/6 | J:156946 | View | ||||
| chronic lymphocytic leukemia |
\Del(14Trim13-Rnaseh2b)6Rdf/\+ \Cd19tm1(cre)Cgn/\Cd19+ |
involves: 129P2/OlaHsd * 129S1/Sv * 129S4/SvJaeSor * C57BL/6 | J:179879 | View | ||||
| chronic lymphocytic leukemia |
\Is(14)1Rdf \Is(14)2Rdf/\Del(14Trim13-Dleu2)4Rdf \Cd19tm1(cre)Cgn/\Cd19+ |
involves: 129P2/OlaHsd * 129S1/Sv * 129S4/SvJaeSor * C57BL/6 | J:156946 | View | ||||
| chronic lymphocytic leukemia |
\Is(14)1Rdf \Is(14)5Rdf/\Del(14Trim13-Rnaseh2b)6Rdf \Cd19tm1(cre)Cgn/\Cd19+ |
involves: 129P2/OlaHsd * 129S1/Sv * 129S4/SvJaeSor * C57BL/6 | J:179879 | View | ||||
| chronic lymphocytic leukemia |
\Mirc30em1Hhzg/\Mirc30em1Hhzg \Tg(Vav1-cre)#Cgp/0 |
involves: 129S4/SvJae * C57BL/6 * C57BL/6NRj | J:320883 | View | ||||
| chronic lymphocytic leukemia | \Mirc30tm1.2Rdf/\Mirc30tm1.2Rdf | involves: 129S1/Sv * 129S4/SvJaeSor * C57BL/6 | J:156946 | View | ||||
| chronic lymphocytic leukemia | \Tg(Igh-Mir29a,-Mir29b-1,-hrGFP)#Cro/0 | FVB/N-Tg(Igh-Mir29a,-Mir29b-1,-hrGFP)#Cro | J:162077 | View | ||||
| chronic lymphocytic leukemia |
\Tg(Igh-Mir29a,-Mir29b-1,-hrGFP)#Cro/0 \Tg(Igh-V186.2-TCL1A)3Cro/0 |
involves: C3H * C57BL/6 * FVB/N | J:162077 | View | ||||
| chronic lymphocytic leukemia | \Tg(Igh-ROR1)1Kip/0 | C57BL/6-Tg(Igh-ROR1)1Kip | J:206368 | View | ||||
| chronic lymphocytic leukemia |
\Tg(Igh-ROR1)1Kip/0 \Tg(Igh-V186.2-TCL1A)3Cro/0 |
B6.Cg-Tg(Igh-ROR1)1Kip Tg(Igh-V186.2-TCL1A)3Cro | J:206368 | View | ||||
| chronic lymphocytic leukemia | \Tg(Igh-TCL1A)1Ypek/0 | FVB/N-Tg(Igh-TCL1A)1Ypek | J:160184 | View | ||||
| chronic lymphocytic leukemia | \Tg(Igh-V186.2-TCL1A)3Cro/0 | B6.Cg-Tg(Igh-V186.2-TCL1A)3Cro | J:206368 | View | ||||
| chronic lymphocytic leukemia | \Tg(Igh-V186.2-TCL1A)3Cro/0 | involves: C3H * C57BL/6 | J:76574 | View | ||||
| chronic lymphocytic leukemia | \Tg(Lck-TNFSF13)3919Mhah/0 | B6.Cg-Tg(Lck-TNFSF13)3919Mhah | J:94628 | View | ||||
| extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue | \Tg(Ly6e-MALT1)#Isg/0 | involves: C57BL/6 * CBA | J:185590 | View | ||||
| follicular lymphoma | \Tg(Vav-BCL2)69Jad/0 | involves: C57BL/6J | J:88565 | View | ||||
| hereditary lymphedema | \Del(8A4-B3)7H/\+ | involves: 101/H * C3H/HeH | J:209628 | View | ||||
| lymphoma | \Tg(Vav1-STAT5B*N642H)726Biat/0 | C57BL/6NCrl-Tg(Vav1-STAT5B*N642H)726Biat | J:257519 | View | ||||
| non-Hodgkin lymphoma | \Tg(EmuSR-HDAC9)1468Kpet/0 | involves: C57BL/6 * CBA | J:237420 | View | ||||
| non-Hodgkin lymphoma |
\Tg(EmuSR-tTa)83Bop/\Tg(EmuSR-tTa)83Bop \Tg(tetO-NPM1/ALK,-luc)2Gde/0 |
involves: FVB/N | J:160236 | View | ||||
| non-Hodgkin lymphoma |
\Tg(EmuSR-tTa)83Bop/\Tg(EmuSR-tTa)83Bop \Tg(tetO-TPM3/ALK,-luc)2Gde/0 |
involves: FVB/N | J:160236 | View | ||||
| plasmacytoma | \Tg(H2-L-IL6)46Kish/\Tg(H2-L-IL6)46Kish | C.B6-Tg(H2-L-IL6)46Kish | J:74377 | View | ||||
| Additional Complex Models | B-cell lymphoma |
\Cd19tm1(cre)Cgn/\Cd19+ \Inpp5dtm1Rav/\Inpp5dtm1Rav \Ptentm1Hwu/\Ptentm1Hwu |
involves: 129P2/OlaHsd * 129S4/SvJae | J:166155 | View | |||
| chronic lymphocytic leukemia | \Ightm1.1(Tag)Rwhe/\Igh+ | involves: 129P2/OlaHsd * C57BL/6 | J:150315 | View | ||||
| chronic lymphocytic leukemia | \Ightm2.1(Tag)Rwhe/\Igh+ | involves: 129P2/OlaHsd * C57BL/6 | J:150315 | View | ||||
| chronic lymphocytic leukemia |
\Ighatm1(Myc)Janz/\Igha+ \Tg(Tnfsf13b)1Fma/0 |
involves: 129S1/Sv * C57BL/6 * DBA/2J | J:166158 | View | ||||
| chronic lymphocytic leukemia |
\Is(14)1Rdf/\Is(14)1Rdf \Is(14)5Rdf/\Is(14)5Rdf \Cd19tm1(cre)Cgn/\Cd19+ |
involves: 129P2/OlaHsd * 129S1/Sv * 129S4/SvJaeSor * C57BL/6 | J:179879 | View | ||||
| chronic lymphocytic leukemia |
\Tg(BCL2/IGH)#Jcre/0 \Tg(H2-K/Igh-Traf2*)#Ywc/0 |
involves: BALB/c * C57BL/6 * CBA/J * FVB/N * SJL/J * SWR/J | J:94116 | View | ||||
| diffuse large B-cell lymphoma |
\Cd19tm1(cre)Cgn/\Cd19+ \Gt(ROSA)26Sortm2(CARD11*L225LI)Jrld/\Gt(ROSA)26Sor+ |
involves: 129P2/OlaHsd | J:228288 | View | ||||
| lymphoma | \Epm2aTg(TcraK,TcrbK)TG-BFlv/\Epm2a+ | involves: C57BL/6 * C57BL/10 * C57BR/cd * CBA/J | J:112696 | View | ||||
| lymphoma |
\Espl1Gt(XL058)Byg/\Espl1+ \Trp53tm1Tyj/\Trp53tm1Tyj |
B6.129-Trp53tm1Tyj Espl1Gt(XL058)Byg | J:174926 | View | ||||
| non-Hodgkin lymphoma |
\Gt(ROSA)26Sortm4(Ikbkb)Rsky/\Gt(ROSA)26Sor+ \Ighg1tm1(cre)Cgn/\Ighg1+ \Prdm1tm2Masu/\Prdm1tm2Masu |
involves: 129P2/OlaHsd * C57BL/6 | J:167612 | View | ||||
| non-Hodgkin lymphoma | \Ighmtm1(Bcl6)Rdf/? | involves: 129/Sv * C57BL/6 | J:98937 | View | ||||