Elp1^{Gt(BGB184)Byg}
Gene trapped Allele Detail

Summary

• Symbol: Elp1^{Gt(BGB184)Byg}
• Name: elongator complex protein 1; gene trap BGB184, BayGenomics
• MGI ID: MGI:3835595
• Gene: Elp1 Location: Chr4:56749680-56802331 bp, - strand Genetic Position: Chr4, 31.66 cM
• Alliance: Elp1^{Gt(BGB184)Byg} page

Mutation origin

• Mutant Cell Line: BGB184
• Germline Transmission: Earliest citation of germline transmission: J:145561
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Gene trapped (Null/knockout, Reporter)
• Mutation: Insertion of gene trap vector
• Mutation details: A gene trap containing a beta-geo cassette was inserted into intron 9. The absence of transcript expression was confirmed by quantitative RT-PCR. (J:145561)

Disease models

Expression

In Structures Affected by this Mutation:

5 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Elp1 Mutation: 68 strains or lines available

References

• Original: J:145561 Chen YT, et al., Loss of mouse Ikbkap, a subunit of elongator, leads to transcriptional deficits and embryonic lethality that can be rescued by human IKBKAP. Mol Cell Biol. 2009 Feb;29(3):736-44
• All: 1 reference(s)