| Disease Term | Human Homologs | Mouse Homologs | Mouse Models | Homology Source | |||
  | type 2 diabetes mellitus | AKT2* | Akt2* | 1 model | Alliance of Genome Resources | ||
| type 2 diabetes mellitus | CDKAL1* | Cdkal1* | 1 model | Alliance of Genome Resources | |||
| type 2 diabetes mellitus | CYB5R4* | Cyb5r4* | 1 model | Alliance of Genome Resources | |||
| type 2 diabetes mellitus | GCK* | Gck* | 2 models | Alliance of Genome Resources | |||
| type 2 diabetes mellitus | HMGA1* | Hmga1*, Hmga1b | 2 models | Alliance of Genome Resources | |||
| type 2 diabetes mellitus | HNF1A* | Hnf1a* | 1 model | Alliance of Genome Resources | |||
| type 2 diabetes mellitus | INS* | Ins2*, Ins1 | 1 model | Alliance of Genome Resources | |||
| type 2 diabetes mellitus | IRS1* | Irs1* | 3 models | Alliance of Genome Resources | |||
| type 2 diabetes mellitus | IRS2* | Irs2* | 4 models | Alliance of Genome Resources | |||
| type 2 diabetes mellitus | LEP* | Lep* | 1 model | Alliance of Genome Resources | |||
| type 2 diabetes mellitus | LEPR* | Lepr* | 7 models | Alliance of Genome Resources | |||
| type 2 diabetes mellitus | PPARD* | Ppard* | 1 model | Alliance of Genome Resources | |||
| type 2 diabetes mellitus | PPP1R3A* | Ppp1r3a* | 1 model | Alliance of Genome Resources | |||
| type 2 diabetes mellitus | SLC2A2* | Slc2a2* | 1 model | Alliance of Genome Resources | |||
| type 2 diabetes mellitus | SLC2A4* | Slc2a4* | 1 model | Alliance of Genome Resources | |||
| | type 2 diabetes mellitus | ASIP | a* | 1 model | Alliance of Genome Resources | ||
| type 2 diabetes mellitus | AR | Ar* | 1 model | Alliance of Genome Resources | |||
| type 2 diabetes mellitus | CTF1 | Ctf1* | 1 model | Alliance of Genome Resources | |||
| type 2 diabetes mellitus | FEM1B | Fem1b* | 1 model | Alliance of Genome Resources | |||
| type 2 diabetes mellitus | FOXM1 | Foxm1* | 1 model | Alliance of Genome Resources | |||
| type 2 diabetes mellitus | GADD45GIP1 | Gadd45gip1* | 1 model | Alliance of Genome Resources | |||
| type 2 diabetes mellitus | HTR2C | Htr2c* | 1 model | Alliance of Genome Resources | |||
| type 2 diabetes mellitus | MADD | Madd* | 1 model | Alliance of Genome Resources | |||
| type 2 diabetes mellitus | MAFA | Mafa* | 1 model | Alliance of Genome Resources | |||
| type 2 diabetes mellitus | PHOX2A | Phox2a* | 2 models | Alliance of Genome Resources | |||
| type 2 diabetes mellitus | PPP1R3C | Ppp1r3c* | 1 model | Alliance of Genome Resources | |||
| type 2 diabetes mellitus | PRKCI | Prkci* | 1 model | Alliance of Genome Resources | |||
| type 2 diabetes mellitus | SDHB | Sdhb* | 1 model | Alliance of Genome Resources | |||
| type 2 diabetes mellitus | SNAP25 | Snap25* | 1 model | Alliance of Genome Resources | |||
| | lipoatrophic diabetes mellitus | LMNA* | Lmna | Alliance of Genome Resources | |||
| type 2 diabetes mellitus | ABCA1* | Abca1 | Alliance of Genome Resources | ||||
| type 2 diabetes mellitus | ABCB1* | Abcb1a, Abcb1b | Alliance of Genome Resources | ||||
| type 2 diabetes mellitus | ABCC8* | Abcc8 | Alliance of Genome Resources | ||||
| type 2 diabetes mellitus | ACE* | Ace | Alliance of Genome Resources | ||||
| type 2 diabetes mellitus | ACP1* | Acp1 | Alliance of Genome Resources | ||||
| type 2 diabetes mellitus | ADAM17* | Adam17 | Alliance of Genome Resources | ||||
| type 2 diabetes mellitus | ADIPOQ* | Adipoq | Alliance of Genome Resources | ||||
| type 2 diabetes mellitus | ADIPOR2* | Adipor2 | Alliance of Genome Resources | ||||
| type 2 diabetes mellitus | ADRA2A* | Adra2a | Alliance of Genome Resources | ||||
| type 2 diabetes mellitus | ADRA2B* | Adra2b | Alliance of Genome Resources | ||||
| type 2 diabetes mellitus | ADRB3* | Adrb3 | Alliance of Genome Resources | ||||
| type 2 diabetes mellitus | AGER* | Ager | Alliance of Genome Resources | ||||
| type 2 diabetes mellitus | AGRP* | Agrp | Alliance of Genome Resources | ||||
| type 2 diabetes mellitus | AHSG* | Ahsg | Alliance of Genome Resources | ||||
| type 2 diabetes mellitus | AKR1B1* | Akr1b1 | Alliance of Genome Resources | ||||
| type 2 diabetes mellitus | ALDH2* | Aldh2 | Alliance of Genome Resources | ||||
| type 2 diabetes mellitus | ALDOB* | Aldob | Alliance of Genome Resources | ||||
| type 2 diabetes mellitus | APOA5* | Apoa5 | Alliance of Genome Resources | ||||
| type 2 diabetes mellitus | APOB* | Apob | Alliance of Genome Resources | ||||
| type 2 diabetes mellitus | APOD* | Apod | Alliance of Genome Resources | ||||
| type 2 diabetes mellitus | APOM* | Apom | Alliance of Genome Resources | ||||
| type 2 diabetes mellitus | AXL* | Axl | Alliance of Genome Resources | ||||
| type 2 diabetes mellitus | BCHE* | Bche | Alliance of Genome Resources | ||||
| type 2 diabetes mellitus | BMAL2* | Bmal2 | Alliance of Genome Resources | ||||
| type 2 diabetes mellitus | BTC* | Btc | Alliance of Genome Resources | ||||
| type 2 diabetes mellitus | CACNA1D* | Cacna1d | Alliance of Genome Resources | ||||
| type 2 diabetes mellitus | CADM2* | Cadm2 | Alliance of Genome Resources | ||||
| type 2 diabetes mellitus | CAPN10* | Capn10 | Alliance of Genome Resources | ||||
| type 2 diabetes mellitus | CASP9* | Casp9 | Alliance of Genome Resources | ||||
| type 2 diabetes mellitus | CASQ1* | Casq1 | Alliance of Genome Resources | ||||
| type 2 diabetes mellitus | CD36* | Cd36 | Alliance of Genome Resources | ||||
| type 2 diabetes mellitus | CD38* | Cd38 | Alliance of Genome Resources | ||||
| type 2 diabetes mellitus | CDK4* | Cdk4 | Alliance of Genome Resources | ||||
| type 2 diabetes mellitus | CEL* | Cel | Alliance of Genome Resources | ||||
| type 2 diabetes mellitus | CLPS* | Clps | Alliance of Genome Resources | ||||
| type 2 diabetes mellitus | CNR1* | Cnr1 | Alliance of Genome Resources | ||||
| type 2 diabetes mellitus | CPE* | Cpe | Alliance of Genome Resources | ||||
| type 2 diabetes mellitus | CYP1A1* | Cyp1a1 | Alliance of Genome Resources | ||||
| type 2 diabetes mellitus | CYP2C9*, CYP2C8, CYP2C18, CYP2C19 | Cyp2c29, Cyp2c37, Cyp2c38, Cyp2c39, Cyp2c50, Cyp2c55, Cyp2c65, Cyp2c66 | Alliance of Genome Resources | ||||
| type 2 diabetes mellitus | CYP11B2*, CYP11B1 | Cyp11b1, Cyp11b2 | Alliance of Genome Resources | ||||
| type 2 diabetes mellitus | DPP4* | Dpp4 | Alliance of Genome Resources | ||||
| type 2 diabetes mellitus | DRD2* | Drd2 | Alliance of Genome Resources | ||||
| type 2 diabetes mellitus | ENPP1* | Enpp1 | Alliance of Genome Resources | ||||
| type 2 diabetes mellitus | ESR1* | Esr1 | Alliance of Genome Resources | ||||
| type 2 diabetes mellitus | F7* | F7 | Alliance of Genome Resources | ||||
| type 2 diabetes mellitus | FABP3* | Fabp3 | Alliance of Genome Resources | ||||
| type 2 diabetes mellitus | FASLG* | Fasl | Alliance of Genome Resources | ||||
| type 2 diabetes mellitus | FFAR1* | Ffar1 | Alliance of Genome Resources | ||||
| type 2 diabetes mellitus | FOXA2* | Foxa2 | Alliance of Genome Resources | ||||
| type 2 diabetes mellitus | FOXC2* | Foxc2 | Alliance of Genome Resources | ||||
| type 2 diabetes mellitus | FTO* | Fto | Alliance of Genome Resources | ||||
| type 2 diabetes mellitus | FXN* | Fxn | Alliance of Genome Resources | ||||
| type 2 diabetes mellitus | GCGR* | Gcgr | Alliance of Genome Resources | ||||
| type 2 diabetes mellitus | GCH1* | Gch1 | Alliance of Genome Resources | ||||
| type 2 diabetes mellitus | GCKR* | Gckr | Alliance of Genome Resources | ||||
| type 2 diabetes mellitus | GFPT2* | Gfpt2 | Alliance of Genome Resources | ||||
| type 2 diabetes mellitus | GHR* | Ghr | Alliance of Genome Resources | ||||
| type 2 diabetes mellitus | GHRL* | Ghrl | Alliance of Genome Resources | ||||
| type 2 diabetes mellitus | GIP* | Gip | Alliance of Genome Resources | ||||
| type 2 diabetes mellitus | GLO1* | Glo1 | Alliance of Genome Resources | ||||
| type 2 diabetes mellitus | GNB3* | Gnb3 | Alliance of Genome Resources | ||||
| type 2 diabetes mellitus | GP6* | Gp6 | Alliance of Genome Resources | ||||
| type 2 diabetes mellitus | GPD2* | Gpd2 | Alliance of Genome Resources | ||||
| type 2 diabetes mellitus | GPX3* | Gpx3 | Alliance of Genome Resources | ||||
| type 2 diabetes mellitus | GRB14* | Grb14 | Alliance of Genome Resources | ||||
| type 2 diabetes mellitus | GSTM1*, GSTM5 | Gstm1, Gstm2, Gstm3, Gstm6 | Alliance of Genome Resources | ||||
| type 2 diabetes mellitus | GSTP1* | Gstp1, Gstp2, Gstp3, Gstp-ps | Alliance of Genome Resources | ||||
| type 2 diabetes mellitus | GSTT1* | Gstt1 | Alliance of Genome Resources | ||||
| type 2 diabetes mellitus | HLA-DQA1*, HLA-DQA2 | H2-Aa | Alliance of Genome Resources | ||||
| type 2 diabetes mellitus | HFE* | Hfe | Alliance of Genome Resources | ||||
| type 2 diabetes mellitus | HIF1A* | Hif1a | Alliance of Genome Resources | ||||
| type 2 diabetes mellitus | HK2* | Hk2 | Alliance of Genome Resources | ||||
| type 2 diabetes mellitus | HMGCR* | Hmgcr | Alliance of Genome Resources | ||||
| type 2 diabetes mellitus | HMOX1* | Hmox1 | Alliance of Genome Resources | ||||
| type 2 diabetes mellitus | HNF1B* | Hnf1b | Alliance of Genome Resources | ||||
| type 2 diabetes mellitus | HNF4A* | Hnf4a | Alliance of Genome Resources | ||||
| type 2 diabetes mellitus | HSD11B1* | Hsd11b1 | Alliance of Genome Resources | ||||
| type 2 diabetes mellitus | HSPA1B*, HSPA1A | Hspa1a, Hspa1b | Alliance of Genome Resources | ||||
| type 2 diabetes mellitus | IAPP* | Iapp | 1 model | Alliance of Genome Resources | |||
| type 2 diabetes mellitus | IDE* | Ide | Alliance of Genome Resources | ||||
| type 2 diabetes mellitus | IFNG* | Ifng | Alliance of Genome Resources | ||||
| type 2 diabetes mellitus | IGF1* | Igf1 | Alliance of Genome Resources | ||||
| type 2 diabetes mellitus | IGF2BP2* | Igf2bp2 | Alliance of Genome Resources | ||||
| type 2 diabetes mellitus | IGF2R* | Igf2r | Alliance of Genome Resources | ||||
| type 2 diabetes mellitus | IGFBP3* | Igfbp3 | Alliance of Genome Resources | ||||
| type 2 diabetes mellitus | IKBKB* | Ikbkb | Alliance of Genome Resources | ||||
| type 2 diabetes mellitus | IL1B* | Il1b | Alliance of Genome Resources | ||||
| type 2 diabetes mellitus | IL1RN* | Il1rn | Alliance of Genome Resources | ||||
| type 2 diabetes mellitus | IL6* | Il6 | Alliance of Genome Resources | ||||
| type 2 diabetes mellitus | IL10* | Il10 | Alliance of Genome Resources | ||||
| type 2 diabetes mellitus | INPPL1* | Inppl1 | Alliance of Genome Resources | ||||
| type 2 diabetes mellitus | INSR* | Insr | 1 model | Alliance of Genome Resources | |||
| type 2 diabetes mellitus | ISL1* | Isl1 | Alliance of Genome Resources | ||||
| type 2 diabetes mellitus | ITGA2* | Itga2 | Alliance of Genome Resources | ||||
| type 2 diabetes mellitus | KCNJ11* | Kcnj11 | Alliance of Genome Resources | ||||
| type 2 diabetes mellitus | KCNQ1* | Kcnq1 | Alliance of Genome Resources | ||||
| type 2 diabetes mellitus | KIF6* | Kif6 | Alliance of Genome Resources | ||||
| type 2 diabetes mellitus | KLF11* | Klf11 | Alliance of Genome Resources | ||||
| type 2 diabetes mellitus | LIPC* | Lipc | Alliance of Genome Resources | ||||
| type 2 diabetes mellitus | LMNA* | Lmna | Alliance of Genome Resources | ||||
| type 2 diabetes mellitus | LPL* | Lpl | Alliance of Genome Resources | ||||
| type 2 diabetes mellitus | LTA* | Lta | Alliance of Genome Resources | ||||
| type 2 diabetes mellitus | MAPK8* | Mapk8 | Alliance of Genome Resources | ||||
| type 2 diabetes mellitus | MAPK8IP1* | Mapk8ip1 | Alliance of Genome Resources | ||||
| type 2 diabetes mellitus | MAPK9* | Mapk9 | Alliance of Genome Resources | ||||
| type 2 diabetes mellitus | MT2A*, MT1A, MT1B, MT1E, MT1F, MT1G, MT1H, MT1L, MT1M, MT1X | Mt1, Mt2 | Alliance of Genome Resources | ||||
| type 2 diabetes mellitus | ND1* | mt-Nd1 | Alliance of Genome Resources | ||||
| type 2 diabetes mellitus | MTHFR* | Mthfr | Alliance of Genome Resources | ||||
| type 2 diabetes mellitus | MTNR1B* | Mtnr1b | Alliance of Genome Resources | ||||
| type 2 diabetes mellitus | MTOR* | Mtor | Alliance of Genome Resources | ||||
| type 2 diabetes mellitus | NEUROD1* | Neurod1 | Alliance of Genome Resources | ||||
| type 2 diabetes mellitus | NEUROG3* | Neurog3 | Alliance of Genome Resources | ||||
| type 2 diabetes mellitus | NOS2* | Nos2 | Alliance of Genome Resources | ||||
| type 2 diabetes mellitus | NPY* | Npy | Alliance of Genome Resources | ||||
| type 2 diabetes mellitus | NR0B2* | Nr0b2 | Alliance of Genome Resources | ||||
| type 2 diabetes mellitus | NR1H2* | Nr1h2 | Alliance of Genome Resources | ||||
| type 2 diabetes mellitus | P2RY12* | P2ry12 | Alliance of Genome Resources | ||||
| type 2 diabetes mellitus | PARL* | Parl | Alliance of Genome Resources | ||||
| type 2 diabetes mellitus | PAX4* | Pax4 | Alliance of Genome Resources | ||||
| type 2 diabetes mellitus | PCK1* | Pck1 | Alliance of Genome Resources | ||||
| type 2 diabetes mellitus | PCSK2* | Pcsk2 | Alliance of Genome Resources | ||||
| type 2 diabetes mellitus | PDX1* | Pdx1 | 1 model | Alliance of Genome Resources | |||
| type 2 diabetes mellitus | PIK3C2G* | Pik3c2g | Alliance of Genome Resources | ||||
| type 2 diabetes mellitus | PIK3R1* | Pik3r1 | Alliance of Genome Resources | ||||
| type 2 diabetes mellitus | PKLR* | Pklr | Alliance of Genome Resources | ||||
| type 2 diabetes mellitus | PLA2G7* | Pla2g7 | Alliance of Genome Resources | ||||
| type 2 diabetes mellitus | PLAT* | Plat | Alliance of Genome Resources | ||||
| type 2 diabetes mellitus | PNPLA3* | Pnpla3 | Alliance of Genome Resources | ||||
| type 2 diabetes mellitus | PON1* | Pon1 | Alliance of Genome Resources | ||||
| type 2 diabetes mellitus | PON2* | Pon2 | Alliance of Genome Resources | ||||
| type 2 diabetes mellitus | PPARG* | Pparg | Alliance of Genome Resources | ||||
| type 2 diabetes mellitus | PPARGC1A* | Ppargc1a | Alliance of Genome Resources | ||||
| type 2 diabetes mellitus | PRKAA2* | Prkaa2 | Alliance of Genome Resources | ||||
| type 2 diabetes mellitus | PTH* | Pth | Alliance of Genome Resources | ||||
| type 2 diabetes mellitus | PTPN1* | Ptpn1 | Alliance of Genome Resources | ||||
| type 2 diabetes mellitus | PTPRD* | Ptprd | Alliance of Genome Resources | ||||
| type 2 diabetes mellitus | RBP4* | Rbp4 | Alliance of Genome Resources | ||||
| type 2 diabetes mellitus | RETN* | Retn | Alliance of Genome Resources | ||||
| type 2 diabetes mellitus | RRAD* | Rrad | Alliance of Genome Resources | ||||
| type 2 diabetes mellitus | SERPINF1* | Serpinf1 | Alliance of Genome Resources | ||||
| type 2 diabetes mellitus | SGCG* | Sgcg | Alliance of Genome Resources | ||||
| type 2 diabetes mellitus | SHBG* | Shbg | Alliance of Genome Resources | ||||
| type 2 diabetes mellitus | SLC2A1* | Slc2a1 | Alliance of Genome Resources | ||||
| type 2 diabetes mellitus | SLC30A8* | Slc30a8 | Alliance of Genome Resources | ||||
| type 2 diabetes mellitus | SOD1* | Sod1 | Alliance of Genome Resources | ||||
| type 2 diabetes mellitus | SOD2* | Sod2 | Alliance of Genome Resources | ||||
| type 2 diabetes mellitus | SOD3* | Sod3 | Alliance of Genome Resources | ||||
| type 2 diabetes mellitus | SORBS1* | Sorbs1 | Alliance of Genome Resources | ||||
| type 2 diabetes mellitus | SPHK1* | Sphk1 | Alliance of Genome Resources | ||||
| type 2 diabetes mellitus | SRC* | Src | Alliance of Genome Resources | ||||
| type 2 diabetes mellitus | SREBF1* | Srebf1 | Alliance of Genome Resources | ||||
| type 2 diabetes mellitus | SREBF2* | Srebf2 | Alliance of Genome Resources | ||||
| type 2 diabetes mellitus | STAT3* | Stat3 | Alliance of Genome Resources | ||||
| type 2 diabetes mellitus | TCF7L2* | Tcf7l2 | Alliance of Genome Resources | ||||
| type 2 diabetes mellitus | TLR4* | Tlr4 | Alliance of Genome Resources | ||||
| type 2 diabetes mellitus | UBE2E2* | Ube2e2 | Alliance of Genome Resources | ||||
| type 2 diabetes mellitus | UCP1* | Ucp1 | Alliance of Genome Resources | ||||
| type 2 diabetes mellitus | UCP3* | Ucp3 | Alliance of Genome Resources | ||||
| type 2 diabetes mellitus | USF1* | Usf1 | Alliance of Genome Resources | ||||
| type 2 diabetes mellitus | UTS2* | Uts2 | Alliance of Genome Resources | ||||
| type 2 diabetes mellitus | VPS26A* | Vps26a | Alliance of Genome Resources | ||||
| type 2 diabetes mellitus | WFS1* | Wfs1 | Alliance of Genome Resources | ||||
| type 2 diabetes mellitus | XRCC1* | Xrcc1 | Alliance of Genome Resources | ||||
Excel File
|
Transgenes and other genome features developed in mice to model this disease.
|
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| Disease Term | Transgenes and Other Genome Features | Mouse Models | |
| type 2 diabetes mellitus | Tg(aP2-SREBF1c)9884Reh | 1 model | |
| type 2 diabetes mellitus | Tg(Ckm-IGF1R*K1003R)1Dlr | 1 model | |
| type 2 diabetes mellitus | Tg(Ins2-IAPP)L13Gjsc | 1 model | |
| type 2 diabetes mellitus | Tg(Mafg-Nfe2l1)1Mym | 1 model | |
| type 2 diabetes mellitus | Tg(Mafg-Nfe2l1)6Mym | 1 model | |
| type 2 diabetes mellitus | Tg(UcpDta)1Kz | 2 models | |
| type 2 diabetes mellitus | Timo | 1 model | |