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Cyp2c66 Gene Detail
Summary
  • Symbol
    Cyp2c66
  • Name
    cytochrome P450, family 2, subfamily c, polypeptide 66
  • Synonyms
    2010301M18Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1917138
    NCBI Gene: 69888
  • Alliance
    genome feature page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr19:39102342-39175200 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 19, 33.75 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    1032 from dbSNP Build 142
  • Strain Annotations
    15
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1917138
 protein coding gene Chr19:39102342-39175516 (+)
129S1/SvImJ ENSMUSG00200026594
 protein coding gene Chr19:35914679-35973105 (+)
A/J ENSMUSG00195010688
 protein coding gene Chr19:36012390-36070831 (+)
AKR/J ENSMUSG00220017614
 protein coding gene Chr19:35896776-35955188 (+)
BALB/cJ ENSMUSG00180029332
 protein coding gene Chr19:36340330-36398767 (+)
C3H/HeJ ENSMUSG00175037583
 protein coding gene Chr19:35758321-35816762 (+)
C57BL/6NJ ENSMUSG00215020011
 protein coding gene Chr19:35771749-35844928 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0022933
 protein coding gene Chr19:35627652-35658532 (+)
CAST/EiJ no annotation
CBA/J ENSMUSG00210028136
 protein coding gene Chr19:35837580-35896014 (+)
DBA/2J ENSMUSG00185031148
 protein coding gene Chr19:36357733-36416183 (+)
FVB/NJ no annotation
JF1/MsJ ENSUMUG00000033022
 protein coding gene Chr19:36506420-36591098 (+)
LP/J ENSMUSG00230033423
 protein coding gene Chr19:37184405-37242844 (+)
NOD/ShiLtJ ENSMUSG00190009872
 protein coding gene Chr19:35747964-35806398 (+)
NZO/HlLtJ ENSMUSG00225042440
 protein coding gene Chr19:40734245-40792668 (+)
PWK/PhJ no annotation
SPRET/EiJ no annotation
WSB/EiJ ENSIUOG00005034669
 protein coding gene Chr19:35259367-35317833 (+)



Homology
more
  • Human Ortholog
    CYP2C8, cytochrome P450 family 2 subfamily C member 8
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CYP2C8, cytochrome P450 family 2 subfamily C member 8
  • Synonyms
    CPC8, CYP2C8DM, CYPIIC8, MP-12/MP-20
  • Links
    NCBI Gene ID: 1558
    UniProt: P10632

  • Chr Location
    10q23.33; chr10:95034359-95069498 (-)  GRCh38
Human Diseases
more
  • Diseases
    21 with human CYP2C19,CYP2C8,CYP2C9 associations

Human Disease Mouse Models
      
IDs
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Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    23
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    597
  • cDNA Data
    5
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 69888 NCBI Gene Model | MGI Sequence Detail 72859 C57BL/6J ±  kb
transcript NM_001011707 RefSeq | MGI Sequence Detail 1630 BALB/c  
polypeptide NP_001011707 RefSeq | MGI Sequence Detail 490 BALB/c  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 5
    cDNA 5

    Microarray probesets 1
References
more
  • Summaries
    All 28
    Gene Ontology 6
    Phenotypes 8
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:341617 Zhang J, et al., CYP eicosanoid pathway mediates colon cancer-promoting effects of dietary linoleic acid. FASEB J. 2023 Jul;37(7):e23009
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/01/2026
MGI 6.24 		The Jackson Laboratory