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Adipor2 Gene Detail
Summary
  • Symbol
    Adipor2
  • Name
    adiponectin receptor 2
  • Synonyms
    1110001I14Rik, D6Ucla1e
  • Feature Type
    protein coding gene
  • IDs
    MGI:93830
    NCBI Gene: 68465
  • Alliance
    gene page
  • Transcription Start Sites
    11 TSS
Location &
Maps
more
  • Sequence Map
    Chr6:119330111-119394489 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 6, 56.78 cM
  • Mapping Data
    8 experiments
Strain
Comparison
more
  • SNPs within 2kb
    314 from dbSNP Build 142
  • Strain Annotations
    18
  • RFLP
    1
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_93830
 protein coding gene Chr6:119330111-119394665 (-)
129S1/SvImJ MGP_129S1SvImJ_G0031193
 protein coding gene Chr6:122140849-122217231 (-)
A/J MGP_AJ_G0031162
 protein coding gene Chr6:117472891-117538705 (-)
AKR/J MGP_AKRJ_G0031093
 protein coding gene Chr6:120621779-120687297 (-)
BALB/cJ MGP_BALBcJ_G0031173
 protein coding gene Chr6:117244782-117313729 (-)
C3H/HeJ MGP_C3HHeJ_G0030536
 protein coding gene Chr6:63609024-63678901 (+)
C57BL/6NJ MGP_C57BL6NJ_G0031631
 protein coding gene Chr6:125261311-125339171 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0028792
 protein coding gene Chr6:114392040-114457109 (-)
CAST/EiJ MGP_CASTEiJ_G0030280
 protein coding gene Chr6:121059088-121134353 (-)
CBA/J MGP_CBAJ_G0030856
 protein coding gene Chr6:130220107-130303918 (-)
DBA/2J MGP_DBA2J_G0031012
 protein coding gene Chr6:116375320-116442473 (-)
FVB/NJ MGP_FVBNJ_G0030964
 protein coding gene Chr6:115498973-115564247 (-)
LP/J MGP_LPJ_G0031091
 protein coding gene Chr6:122156595-122228342 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0030998
 protein coding gene Chr6:134244108-134313534 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0031660
 protein coding gene Chr6:120664783-120732820 (-)
PWK/PhJ MGP_PWKPhJ_G0029995
 protein coding gene Chr6:115381430-115448416 (-)
SPRET/EiJ MGP_SPRETEiJ_G0029824
 protein coding gene Chr6:119375530-119446074 (-)
WSB/EiJ MGP_WSBEiJ_G0030363
 protein coding gene Chr6:120928820-120999488 (-)



Homology
more
  • Human Ortholog
    ADIPOR2, adiponectin receptor 2
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ADIPOR2, adiponectin receptor 2
  • Synonyms
    ACDCR2, PAQR2
  • Links
    NCBI Gene ID: 79602
    neXtProt AC: NX_Q86V24
    UniProt: Q86V24

  • Chr Location
    12p13.33; chr12:1690981-1788679 (+)  GRCh38.p7
Human Diseases
more
  • Diseases
    2 with human ADIPOR2 associations

Human Disease Mouse Models
      
IDs
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    46 phenotypes from 5 alleles in 6 genetic backgrounds
    10 phenotypes from multigenic genotypes
    33 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Mice homozygous for disruptions in this gene display small testes and epididymis, degeneration of the seminiferous tubules, abnormal sperm maturation and abnormal thermogenesis.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    30
  • GO References
    9
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    1059
  • Tissues
    199
  • cDNA Data
    206
  • Literature Summary
    13
  • Comparison Matrix
    Gene Expression + Phenotype
    • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 68465 NCBI Gene Model | MGI Sequence Detail 64379 C57BL/6J ±  kb
    transcript NM_001355692 RefSeq | MGI Sequence Detail 4152 C57BL/6  
    polypeptide Q8BQS5 UniProt | EBI | MGI Sequence Detail 386 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 211
      cDNA 207
      Primer pair 3
      Other 1

      Microarray probesets 5
    Other
    Accession IDs
    less
    MGD-MRK-7736, MGI:1889386, MGI:1915715, MGI:2141699
    References
    more
    • Summaries
      All 86
      Developmental Gene Expression 13
      Gene Ontology 9
      Phenotypes 33
    • Earliest
      J:15567 Warden CH, et al., Linkage mapping of 40 randomly isolated liver cDNA clones in the mouse. Genomics. 1993 Nov;18(2):295-307
    • Latest
      J:327433 Song Z, et al., The conserved Mediator subunit cyclin C (CCNC) is required for brown adipocyte development and lipid accumulation. Mol Metab. 2022 Jul 19;64:101548
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    01/24/2023
    MGI 6.22     		The Jackson Laboratory