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Disease Ontology Browser
metabolic dysfunction-associated steatotic liver disease (DOID:0080208)
Alliance: disease page
Synonyms: MAFLD; MASLD; metabolic dysfunction-associated fatty liver disease; metabolic dysfunction-related steatotic liver disease; metabolic-associated fatty liver disease; NAFL; NAFLD; non-alcoholic fatty liver; non-alcoholic fatty liver disease; nonalcoholic fatty liver; nonalcoholic fatty liver disease
Alt IDs: OMIM:613282, OMIM:613387, MESH:D065626
Definition: A steatotic liver disease characterized by at least one of five specified cardiometabolic risk factors and no other discernible cause with normal to no alcohol use. The five cardiometabolic risk factors are: (1) higher than normal body mass index or waist circumference; (2) higher than normal serum glucose or glycated hemoglobin level, or type 2 diabetes; (3) higher than normal blood pressure or hypertensive treatment; (4) higher than normal plasma triglycerides or lipid lowering treatment; and (5) lower than normal plasma high-density lipoprotein cholesterol.

Disease References using Mouse Models (21)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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