Adipor2 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Adipor2
adiponectin receptor 2
MGI:93830

47 phenotypes from 5 alleles in 6 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Adipor2^tm1.1Kry/Adipor2^tm1.1Kry Tg(Col1a1-cre)1Kry/0 involves: 129 * C57BL/6J * FVB	normal homeostasis/metabolism phenotype	J:199264
	normal skeleton phenotype	J:199264
Adipor2^{tm1b(EUCOMM)Hmgu}/Adipor2^{tm1b(EUCOMM)Hmgu} C57BL/6N-Adipor2^{tm1b(EUCOMM)Hmgu}/H	decreased grip strength	J:211773
	decreased lymphocyte cell number	J:211773
	increased neutrophil cell number	J:211773
	limb grasping	J:211773
	male infertility	J:211773
	small testis	J:211773
Adipor2^tm1Dgen/Adipor2^tm1Dgen B6.129P2-Adipor2^tm1Dgen	abnormal abdominal fat pad morphology	J:122027
	abnormal brown fat cell morphology	J:122027
	abnormal hormone level	J:122027
	abnormal lipid homeostasis	J:122027
	decreased brown adipose tissue mass	J:122027
	decreased circulating cholesterol level	J:122027
	decreased circulating HDL cholesterol level	J:122027
	decreased circulating insulin level	J:122027
	decreased fat cell size	J:122027
	decreased gonadal fat pad weight	J:122027
	decreased lean body mass	J:122027
	decreased liver triglyceride level	J:122027
	decreased percent body fat/body weight	J:122027
	decreased renal fat pad weight	J:122027
	decreased susceptibility to diet-induced obesity	J:122027
	decreased testis weight	J:122027
	improved glucose tolerance	J:122027
	increased brain weight	J:122027
	increased circulating adiponectin level	J:122027
	increased energy expenditure	J:122027
	increased food intake	J:122027
	increased locomotor activity	J:122027
Adipor2^tm1Dgen/Adipor2^tm1Dgen B6.129P2-Adipor2^tm1Dgen/J	abnormal adaptive thermogenesis	J:210480
	normal homeostasis/metabolism phenotype	J:210480
	impaired adaptive thermogenesis	J:210480
Adipor2^tm1Dgen/Adipor2^tm1Dgen involves: 129P2/OlaHsd * C57BL/6	abnormal spermatogenesis	J:101679
	decreased epididymis weight	J:101679
	decreased testis weight	J:101679
	multinucleated giant male germ cells	J:101679
	oligozoospermia	J:101679
	seminiferous tubule degeneration	J:101679
Adipor2^tm1Tka/Adipor2^tm1Tka involves: 129S4/SvJae * C57BL/6	abnormal glucose homeostasis	J:117919
	hyperglycemia	J:117919
	impaired glucose tolerance	J:117919
	increased circulating insulin level	J:117919
	insulin resistance	J:117919
Adipor2^tm2Dgen/Adipor2^tm2Dgen involves: 129P2/OlaHsd * C57BL/6	abnormal glucose homeostasis	J:129554
	decreased circulating cholesterol level	J:129554
	decreased circulating HDL cholesterol level	J:129554
	decreased circulating insulin level	J:129554
	decreased circulating LDL cholesterol level	J:129554
	decreased circulating triglyceride level	J:129554
	decreased circulating VLDL cholesterol level	J:129554
	decreased pancreatic beta cell number	J:129554
	decreased susceptibility to diet-induced obesity	J:129554
	increased circulating adiponectin level	J:129554
	increased circulating glucose level	J:129554

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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