Adipor2^tm2Dgen
Targeted Allele Detail

Summary

• Symbol: Adipor2^tm2Dgen
• Name: adiponectin receptor 2; targeted mutation 2, Deltagen
• MGI ID: MGI:3770154
• Synonyms: AdipoR2^-
• Gene: Adipor2 Location: Chr6:119330111-119394489 bp, - strand Genetic Position: Chr6, 56.78 cM
• Alliance: Adipor2^tm2Dgen page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:129554
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129P2/OlaHsd
• Project Collection: Deltagen

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exon 5 was replaced with an IRES-betageo cassette. The absence of full length transcript was confirmed by quantitative RT-PCR. (J:129554)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Adipor2 Mutation: 75 strains or lines available

References

• Original: J:129554 Liu Y, et al., Deficiency of adiponectin receptor 2 reduces diet-induced insulin resistance but promotes type 2 diabetes. Endocrinology. 2007 Feb;148(2):683-92
• All: 1 reference(s)