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Cyp2c54 Gene Detail
Summary
  • Symbol
    Cyp2c54
  • Name
    cytochrome P450, family 2, subfamily c, polypeptide 54
  • Feature Type
    protein coding gene
  • IDs
    MGI:3642960
    NCBI Gene: 404195
  • Alliance
    genome feature page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr19:40026384-40062271 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 19, 34.24 cM, cytoband C3
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1235 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3642960
 protein coding gene Chr19:40026383-40062289 (-)
129S1/SvImJ ENSMUSG00200027517
 protein coding gene Chr19:36772233-36808029 (-)
A/J ENSMUSG00195010834
 protein coding gene Chr19:36872102-36907897 (-)
AKR/J ENSMUSG00220018321
 protein coding gene Chr19:36674650-36710451 (-)
BALB/cJ ENSMUSG00180030306
 protein coding gene Chr19:37124536-37160331 (-)
C3H/HeJ ENSMUSG00175034556
 protein coding gene Chr19:36644941-36680901 (-)
C57BL/6NJ ENSMUSG00215021091
 protein coding gene Chr19:36714913-36750802 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0022935
 protein coding gene Chr19:36808584-36817361 (+)
CAST/EiJ ENSTCUG00005014632
 protein coding gene Chr19:36317983-36359207 (-)
CBA/J ENSMUSG00210029269
 protein coding gene Chr19:36727149-36763103 (-)
DBA/2J ENSMUSG00185029688
 protein coding gene Chr19:37247312-37283266 (-)
FVB/NJ ENSMUSG00205006114
 protein coding gene Chr19:36196405-36232203 (-)
JF1/MsJ ENSUMUG00000034105
 protein coding gene Chr19:37412317-37448148 (-)
LP/J ENSMUSG00230034637
 protein coding gene Chr19:38042440-38078234 (-)
NOD/ShiLtJ ENSMUSG00190010526
 protein coding gene Chr19:36603398-36639193 (-)
NZO/HlLtJ ENSMUSG00225043255
 protein coding gene Chr19:41592260-41628056 (-)
PWK/PhJ ENSLUMG00010001054
 protein coding gene Chr19:36579005-36614795 (-)
SPRET/EiJ ENSMSPG00010022341
 protein coding gene Chr19:36343722-36377653 (-)
WSB/EiJ ENSIUOG00005038050
 protein coding gene Chr19:36116365-36152164 (-)



Homology
more
  • Human Ortholog
    CYP2C8, cytochrome P450 family 2 subfamily C member 8
  • Vertebrate Orthologs
    1
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CYP2C8, cytochrome P450 family 2 subfamily C member 8
  • Synonyms
    CPC8, CYP2C8DM, CYPIIC8, MP-12/MP-20
  • Links
    NCBI Gene ID: 1558
    UniProt: P10632

  • Chr Location
    10q23.33; chr10:95034359-95069498 (-)  GRCh38
Human Diseases
more
  • Diseases
    21 with human CYP2C19,CYP2C8,CYP2C9 associations

Human Disease Mouse Models
      
IDs
IDs
IDs
IDs
IDs
IDs
IDs
IDs
IDs
IDs
IDs
IDs
IDs
IDs
IDs
IDs
IDs
IDs
IDs
IDs
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    37
  • GO References
    8
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    597
  • cDNA Data
    29
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000067225 Ensembl Gene Model | MGI Sequence Detail 35888 C57BL/6J ±  kb
transcript ENSMUST00000048959 Ensembl | MGI Sequence Detail 1786 Not Applicable  
polypeptide ENSMUSP00000048284 Ensembl | MGI Sequence Detail 490 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 29
    cDNA 29

    Microarray probesets 1
References
more
  • Summaries
    All 27
    Gene Ontology 8
    Phenotypes 8
  • Earliest
    J:113341 Wang H, et al., Cloning, expression, and characterization of three new mouse cytochrome p450 enzymes and partial characterization of their fatty acid oxidation activities. Mol Pharmacol. 2004 May;65(5):1148-58
  • Latest
    J:341617 Zhang J, et al., CYP eicosanoid pathway mediates colon cancer-promoting effects of dietary linoleic acid. FASEB J. 2023 Jul;37(7):e23009
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/01/2026
MGI 6.24 		The Jackson Laboratory