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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Rag2
recombination activating gene 2
MGI:97849
134 phenotypes from multigenic genotypes
Export: Excel File
Allelic Composition
Genetic Background		 Annotated Term Reference
\Apoetm1Unc/\Apoetm1Unc
\Rag2tm1Fwa/\Rag2+
involves: 129P2/OlaHsd * 129S/SvEv 		abnormal aorta morphology J:59156
decreased body weight J:59156
decreased circulating cholesterol level J:59156
decreased circulating HDL cholesterol level J:59156
increased uterus weight J:59156
\Apoetm1Unc/\Apoetm1Unc
\Rag2tm1Fwa/\Rag2tm1Fwa
involves: 129P2/OlaHsd * 129S/SvEv 		abnormal aorta morphology J:59156
decreased body weight J:59156
decreased circulating cholesterol level J:59156
decreased circulating HDL cholesterol level J:59156
increased uterus weight J:59156
\Cbltm1.1Hua/\Cbltm1.1Hua
\Lcp2tm1Gak/\Lcp2tm1Gak
\Rag2tm1Fwa/\Rag2tm1Fwa
involves: 129P2/OlaHsd * 129S/SvEv * 129S1/Sv * 129X1/SvJ 		abnormal T cell differentiation J:91369
\Ccnd3tm1Pisc/\Ccnd3tm1Pisc
\Rag2tm1Fwa/\Rag2tm1Fwa
involves: 129S/SvEv 		increased T cell proliferation J:88120
\Cd8atm1Asin/\Cd8atm1Asin
\Rag2tm1Fwa/\Rag2tm1Fwa
\Tg(TcraH-Y,TcrbH-Y)71Vbo/?
involves: 129S/SvEv * 129S1/Sv * 129X1/SvJ * C57BL/6J * DBA/2J 		abnormal CD8-positive, alpha beta T cell morphology J:125259
\Csf1tm1.1(CSF1)Flv/\Csf1tm1.1(CSF1)Flv
\Csf2/Il3tm1.1(CSF2,IL3)Flv/\Csf2/Il3tm1.1(CSF2,IL3)Flv
\Il2rgtm1.1Flv/\Il2rgtm1.1Flv
\Rag2tm1.1Flv/\Rag2tm1.1Flv
\Tg(SIRPA)1Flv/0
\Thpotm1.1(TPO)Flv/\Thpotm1.1(TPO)Flv
involves: 129S4/SvJae * BALB/cAnNTac 		abnormal response to transplant J:207289
\Csf1tm1.1(CSF1)Flv/\Csf1tm1.1(CSF1)Flv
\Csf2/Il3tm1.1(CSF2,IL3)Flv/\Csf2/Il3tm1.1(CSF2,IL3)Flv
\Il2rgtm1.1Flv/\Il2rgtm1.1Flv
\Rag2tm1.1Flv/\Rag2tm1.1Flv
\Thpotm1.1(TPO)Flv/\Thpotm1.1(TPO)Flv
involves: 129S4/SvJae * BALB/cAnNTac 		abnormal response to transplant J:207289
\Csf1tm1.1(CSF1)Flv/\Csf1tm1.1(CSF1)Flv
\Il2rgtm1.1Flv/\Il2rgtm1.1Flv
\Csf2/Il3tm1.1(CSF2,IL3)Flv/\Csf2/Il3tm1.1(CSF2,IL3)Flv
\Rag2tm1.1Flv/\Rag2tm1.1Flv
\Tg(SIRPA)1Flv/0
\Thpotm1.1(TPO)Flv/\Thpotm1.1(TPO)Flv
involves: 129S4/SvJae * BALB/cAnNTac 		abnormal response to transplant J:207289
\Csf1tm1.1(CSF1)Flv/\Csf1tm1.1(CSF1)Flv
\Il2rgtm1.1Flv/\Il2rgtm1.1Flv
\Csf2/Il3tm1.1(CSF2,IL3)Flv/\Csf2/Il3tm1.1(CSF2,IL3)Flv
\Rag2tm1.1Flv/\Rag2tm1.1Flv
\Thpotm1.1(TPO)Flv/\Thpotm1.1(TPO)Flv
involves: 129S4/SvJae * BALB/cAnNTac 		abnormal response to transplant J:207289
\Csf1tm1.1(CSF1)Flv/\Csf1tm1.1(CSF1)Flv
\Il2rgtm1.1Flv/\Il2rgtm1.1Flv
\Rag2tm1.1Flv/\Rag2tm1.1Flv
involves: 129P2/OlaHsd * 129S/SvEv * 129S4/SvJae * BALB/cAnNTac 		abnormal immune system physiology J:177073
normal craniofacial phenotype J:177073
normal hematopoietic system phenotype J:177073
normal immune system phenotype J:177073
normal skeleton phenotype J:177073
\Csf2/Il3tm1.1(CSF2,IL3)Flv/\Csf2/Il3tm1.1(CSF2,IL3)Flv
\Il2rgtm1.1Flv/\Il2rgtm1.1Flv
\Rag2tm1.1Flv/\Rag2tm1.1Flv
involves: 129S4/SvJae * BALB/cAnNCr * BALB/cAnNTac 		abnormal response to transplant J:168302
\Ctcftm2Gal/\Ctcftm2Gal
\Rag2tm1Fwa/\Rag2tm1Fwa
\Tg(Lck-cre)1Cwi/0
involves: 129P2/OlaHsd * 129S/SvEv * C57BL/6 * C57BL/10 		decreased double-positive T cell number J:143271
\Ctla4tm1Shr/\Ctla4tm1Shr
\Rag2tm1Fwa/\Rag2tm1Fwa
\Tg(DO11.10)10Dlo/0
involves: 129S/Sv * BALB/c * C3H * C57BL/6 		abnormal cytokine secretion J:110446
abnormal T cell physiology J:110446
normal immune system phenotype J:110446
\Del(7Pira1-Lilra6)1Fgla/\Del(7Pira1-Lilra6)1Fgla
\Il2rgtm1Wjl/\Il2rgtm1Wjl
\Rag2tm1Fwa/\Rag2tm1Fwa
involves: C57BL/6J * C57BL/6NTac 		abnormal response to transplant J:290663
\Dnajc11spc/\Dnajc11spc
\Rag2tm1Fwa/\Rag2tm1Fwa
involves: 129S6/SvEvTac * C57BL/6J 		normal abnormal behavior J:221543
\Dusp5tm1.1Achn/\Dusp5tm1.1Achn
\Rag2tm1.1Cgn/\Rag2tm1.1Cgn
involves: C57BL/6NCrl 		abnormal eosinophil physiology J:218203
abnormal susceptibility to parasitic infection J:218203
increased eosinophil cell number J:218203
\Erap1tm1Luc/\Erap1tm1Luc
\Rag2tm1Fwa/\Rag2tm1Fwa
\Tg(TcrLCMV)327Sdz/\Tg(TcrLCMV)327Sdz
involves: 129S/SvEv * 129S6/SvEvTac * C57BL/6 * C57BL/10SgSnAi * DBA/2 		normal immune system phenotype J:122479
\Errfi1tm1Gvw/\Errfi1tm1Gvw
\Rag2tm1Fwa/\Rag2tm1Fwa
involves: 129S/SvEv 		osteoarthritis J:100927
\Gata3tm1Jfz/\Gata3tm1Jfz
\Rag2tm1Fwa/\Rag2tm1Fwa
\Tg(Cd4-cre)1Cwi/0
\Tg(Tcra5CC7,Tcrb5CC7)IWep/0
involves: 129S/SvEv * C57BL/6 * DBA/2 		abnormal T cell differentiation J:141145
\Gpr15tm1.1Litt/\Gpr15tm1.1Litt
\Rag2tm1Fwa/\Rag2tm1Fwa
\Tg(TcraTcrb)425Cbn/0
involves: 129P2/OlaHsd * 129S/SvEv * BALB/c * C57BL/6 		abnormal immune system physiology J:199126
\H2b/\H2b
\Nfkbidtm1Clay/\Nfkbidtm1Clay
\Rag2tm1Fwa/\Rag2tm1Fwa
\Tg(TcraN15,TcrbN15)L2Elre/?
involves: 129S/SvEv * 129S6/SvEvTac * C57BL/6 		abnormal thymocyte activation J:132071
decreased interleukin-2 secretion J:132071
decreased T cell proliferation J:132071
\H2b/\H2b
\Rag2tm1Fwa/\Rag2tm1Fwa
\Tg(TcraN15,TcrbN15)L2Elre/?
involves: 129S/SvEv * C57BL/6 		abnormal cytotoxic T cell physiology J:133112
arrested T cell differentiation J:133112
decreased CD4-positive, alpha-beta T cell number J:133112
increased CD8-positive, alpha-beta T cell number J:133112
increased T cell proliferation J:133112
\H2d/\H2d
\Rag2tm1Fwa/\Rag2tm1Fwa
\Tg(TcraN15,TcrbN15)L2Elre/?
involves: 129S/SvEv * C57BL/6 		arrested T cell differentiation J:133112
decreased CD4-positive, alpha-beta T cell number J:133112
decreased CD8-positive, alpha-beta T cell number J:133112
\Hgftm1Jmw/\Hgftm1Jmw
\Rag2tm1Fwa/\Rag2tm1Fwa
involves: 129S/SvEv * 129S1/Sv * 129X1/SvJ * C57BL/6 		decreased hepatocyte proliferation J:97145
impaired liver regeneration J:97145
\Ikzf1tm3.1Mbu/\Ikzf1tm3.1Mbu
\Cd79atm1(cre)Reth/\Cd79a+
\Rag2tm1Fwa/\Rag2tm1Fwa
involves: 129P2/OlaHsd * 129S/SvEv * BALB/c * C57BL/6 * SJL 		decreased pro-B cell number J:209928
\Il2tm1Hor/\Il2tm1Hor
\Rag2tm1Fwa/\Rag2+
involves: 129P2/OlaHsd * 129S/SvEv * C57BL/6 		abnormal intestinal epithelium morphology J:29999
abnormal intestinal goblet cell morphology J:29999
anemia J:29999
cachexia J:29999
colitis J:29999
diarrhea J:29999
enlarged mesenteric lymph nodes J:29999
hunched posture J:29999
rectal hemorrhage J:29999
rectal prolapse J:29999
\Il2tm1Hor/\Il2tm1Hor
\Rag2tm1Fwa/\Rag2tm1Fwa
involves: 129P2/OlaHsd * 129S/SvEv * C57BL/6 		abnormal blood cell morphology/development J:29999
normal immune system phenotype J:29999
\Il2tm1Hor/\Il2tm1Hor
\Rag2tm1Fwa/\Rag2tm1Fwa
\Tg(Tcra5CC7,Tcrb5CC7)IWep/0
involves: 129P2/OlaHsd * C57BL/10 		abnormal T cell number J:120176
increased T-helper 17 cell number J:120176
\Il2rbtm1Mak/\Il2rbtm1Mak
\Rag2tm1Fwa/\Rag2tm1Fwa
involves: 129 * 129S/SvEv 		decreased NK cell number J:142654
\Il2rgtm1.1Flv/\Il2rgtm1.1Flv
\Csf2/Il3tm1.1(CSF2,IL3)Flv/\Csf2/Il3tm1.1(CSF2,IL3)Flv
\Rag2tm1.1Flv/\Rag2tm1.1Flv
involves: 129S4/SvJae * BALB/cAnNCr * BALB/cAnNTac 		abnormal response to transplant J:168302
\Il2rgtm1.1Flv/\Il2rgtm1.1Flv
\Rag2tm1.1Flv/\Rag2tm1.1Flv
involves: 129S4/SvJae * BALB/cAnNTac 		abnormal response to transplant J:168303
increased susceptibility to bacterial infection J:168303
\Il2rgtm1.1Flv/\Il2rgtm1.1Flv
\Rag2tm1.1Flv/\Rag2tm1.1Flv
\Thpotm1.1(TPO)Flv/\Thpotm1.1(TPO)Flv
involves: 129S4/SvJae * BALB/cAnNTac 		abnormal response to transplant J:168301
thrombocytopenia J:168301
\Il2rgtm1.1Flv/Y
\Rag2tm1.1Flv/\Rag2tm1.1Flv
involves: 129S4/SvJae * BALB/cAnNTac 		abnormal response to transplant J:168303
increased susceptibility to bacterial infection J:168303
\Il2rgtm1Cgn/\Il2rgtm1Cgn
\Rag2tm1Fwa/\Rag2tm1Fwa
involves: 129P2/OlaHsd * 129S/SvEv 		abnormal interleukin secretion J:142654
decreased NK cell number J:142654
increased susceptibility to bacterial infection J:142654
\Il2rgtm1Cgn/Y
\Rag2tm1Fwa/\Rag2tm1Fwa
B6.129-Rag2tm1Fwa Il2rgtm1Cgn 		absent B cells J:132257
absent NK cells J:132257
absent T cells J:132257
\Il2rgtm1Wjl/\Il2rgtm1Wjl
\Rag2tm1Fwa/\Rag2tm1Fwa
involves: 129S/SvEv * 129S4/SvJae 		abnormal interferon secretion J:140483
absent NK cells J:140483
absent T cells J:140483
increased susceptibility to bacterial infection J:140483
increased susceptibility to induced morbidity/mortality J:140483
lung inflammation J:140483
\Il6sttm1Thir/\Il6sttm1Thir
\Rag2tm1Fwa/\Rag2tm1Fwa
involves: 129S/SvEv * C57BL/6 		normal immune system phenotype J:133059
\Il7tm1Dnax/\Il7tm1Dnax
\Rag2tm1Fwa/\Rag2tm1Fwa
involves: 129P2/OlaHsd * 129S/SvEv 		decreased NK cell number J:132257
\Il12atm1Jm/\Il12atm1Jm
\Rag2tm1Fwa/\Rag2tm1Fwa
involves: 129S/SvEv * 129S1/Sv * 129S6/SvEvTac 		abnormal interferon secretion J:140483
decreased susceptibility to bacterial infection J:140483
lung inflammation J:140483
\Il12btm1Jm/\Il12btm1Jm
\Rag2tm1Fwa/\Rag2tm1Fwa
involves: 129S/SvEv * 129S1/Sv 		abnormal chemokine secretion J:140483
abnormal interferon secretion J:140483
increased susceptibility to bacterial infection J:140483
lung inflammation J:140483
\Il15tm1Imx/\Il15tm1Imx
\Rag2tm1Fwa/\Rag2tm1Fwa
involves: 129S/SvEv * C57BL/6 		decreased NK cell number J:132257
\Il23rtm1.1Ngh/\Il23rtm1.1Ngh
\Rag2tm1Fwa/\Rag2tm1Fwa
involves: 129S/SvEv * C57BL/6 		abnormal circulating interleukin level J:216867
abnormal large intestine crypts of Lieberkuhn morphology J:216867
decreased colon length J:216867
decreased interleukin-17 secretion J:216867
weight loss J:216867
\Lattm6.1(HBEGF/EGFP)Mal/?
\Rag2tm1Fwa/\Rag2tm1Fwa
\Tg(TcraH-Y,TcrbH-Y)1Pas/?
involves: 129S/SvEv * 129S2/SvPas * C57BL/6 		abnormal T cell physiology J:138401
\Lime1tm1.1Mal/\Lime1tm1.1Mal
\Rag2tm1Fwa/\Rag2tm1Fwa
\Tg(TcraH-Y,TcrbH-Y)1Pas/?
B6.Cg-Rag2tm1Fwa Lime1tm1.1Mal Tg(TcraH-Y,TcrbH-Y)1Pas 		abnormal CD4-positive T cell differentiation J:126321
increased CD4-positive, alpha-beta T cell number J:126321
\Mmp9tm1Tvu/\Mmp9tm1Tvu
\Rag2tm1Fwa/\Rag2tm1Fwa
B6.129S-Rag2tm1Fwa Mmp9tm1Tvu 		decreased tumor incidence J:105098
\Mmp9tm1Tvu/\Mmp9tm1Tvu
\Rag2tm1Fwa/\Rag2tm1Fwa
involves: 129S/SvEv * 129S6/SvEvTac * C57BL/6 * FVB/N 		abnormal tumor morphology J:140033
decreased metastatic potential J:140033
decreased tumor growth/size J:140033
\Mogtm1Dpd/\Mogtm1Dpd
\Rag2tm1Cgn/\Rag2tm1Cgn
\Tg(Tcra2D2,Tcrb2D2)1Kuch/0
involves: 129S2/SvPas * C57BL/6 		increased susceptibility to experimental autoimmune encephalomyelitis J:151335
\Nfkbiztm1Aki/\Nfkbiztm1Aki
\Rag2tm1Fwa/\Rag2tm1Fwa
involves: 129P2/OlaHsd * 129S/SvEv 		normal immune system phenotype J:194832
\Nr3c1tm1.1Jda/\Nr3c1tm1.1Jda
\Rag2tm1.1Cgn/\Rag2tm1.1Cgn
\Tg(Lck-cre)548Jxm/0
\Tg(TcrAND)53Hed/0
B6.Cg-Rag2tm1.1Cgn Nr3c1tm1.1Jda Tg(Lck-cre)548Jxm Tg(TcrAND)53Hed 		decreased double-positive T cell number J:189951
\Pdpk1tm1.1Mlw/\Pdpk1tm1.1Mlw
\Rag2tm1Fwa/\Rag2tm1Fwa
\Tnfrsf4tm2(cre)Nik/\Tnfrsf4+
\Gt(ROSA)26Sortm1(EYFP)Cos/\Gt(ROSA)26Sor+
involves: 129S/SvEv * 129X1/SvJ * C57BL/6 		abnormal keratinocyte differentiation J:226194
dermatitis J:226194
epidermal hyperplasia J:226194
premature death J:226194
\Prss16tm1.1Mal/\Prss16+
\Rag2tm1Fwa/\Rag2tm1Fwa
\Tg(TcraH-Y,TcrbH-Y)1Pas/?
involves: 129S/SvEv * 129S2/SvPas * C57BL/6 		abnormal positive T cell selection J:148034
decreased CD4-positive, alpha-beta T cell number J:148034
decreased single-positive T cell number J:148034
lymph node hypoplasia J:148034
\Prss16tm1.1Mal/\Prss16tm1.1Mal
\Rag2tm1Fwa/\Rag2tm1Fwa
\Tg(TcraH-Y,TcrbH-Y)1Pas/?
involves: 129S/SvEv * 129S2/SvPas * C57BL/6 		abnormal positive T cell selection J:148034
decreased CD4-positive, alpha-beta T cell number J:148034
decreased double-positive T cell number J:148034
decreased single-positive T cell number J:148034
lymph node hypoplasia J:148034
spleen hypoplasia J:148034
thymus hypoplasia J:148034
\Rag2tm1.1Cgn/\Rag2tm1.1Cgn
\Tg(HLA-DR2)#Lfug/0
\Tg(TCROb.1A12)#Lfug/0
involves: C57BL/6 * DBA/2 		autoimmune response J:134764
CNS inflammation J:134764
demyelination J:134764
hindlimb paralysis J:134764
\Rag2tm1.1Cgn/\Rag2tm1.1Cgn
\Trex1tm1Tld/\Trex1tm1Tld
involves: 129P2/OlaHsd * C57BL/6 		normal immune system phenotype J:181257
normal mortality/aging J:181257
\Rag2tm1.1Desi/\Rag2tm1.1Desi
\Trp53tm1Tyj/\Trp53tm1Tyj
involves: 129S2/SvPas * 129X1/SvJ * C57BL/6 		increased B cell derived lymphoma incidence J:168974
increased T cell derived lymphoma incidence J:168974
\Rag2tm1.1Mss/\Rag2tm1.1Mss
involves: 129S6/SvEvTac 		abnormal lymphopoiesis J:171970
abnormal pre-B cell morphology J:171970
decreased pre-B cell number J:171970
increased DN3 thymocyte number J:171970
normal neoplasm J:170462
\Rag2tm1.1Mss/\Rag2tm1.1Mss
\Trp53tm1Tyj/\Trp53tm1Tyj
involves: 129S2/SvPas * 129S6/SvEvTac 		abnormal chromosome morphology J:170462
aneuploidy J:170462
increased lymphoma incidence J:170462
increased T cell derived lymphoma incidence J:170462
premature death J:170462
\Rag2tm1Cgn/\Rag2tm1Cgn
\Xrcc4tm1Fwa/\Xrcc4tm2Fwa
\Tg(Cr2-cre)3Cgn/?
involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6 		abnormal class switch recombination J:150339
spontaneous chromosome breakage J:150339
\Rag2tm1Fwa/\Rag2+
\Trp53tm1Tyj/\Trp53tm1Tyj
involves: 129S/SvEv * 129S2/SvPas * C57BL/6J 		increased T cell derived lymphoma incidence J:47667
premature death J:47667
\Rag2tm1Fwa/\Rag2+
\Tg(LPV-TAg1135)11Tvd/0
involves: 129S/SvEv * C57BL/6 * DBA/2 		increased T cell derived lymphoma incidence J:47667
premature death J:47667
\Rag2tm1Fwa/\Rag2tm1Fwa
\Cd47tm1Fpl/\Cd47tm1Fpl
\Il2rgtm1Cgn/Y
involves: 129P2/OlaHsd * 129S/SvEv * 129S7/SvEvBrd * C57BL/6 		absent peripheral lymph nodes J:203904
decreased CD4-positive, alpha-beta T cell number J:203904
decreased lymphocyte cell number J:203904
decreased susceptibility to graft versus host disease J:203904
increased activated T cell number J:203904
increased CD8-positive, alpha-beta T cell number J:203904
increased susceptibility to Retroviridae infection J:203904
\Rag2tm1Fwa/\Rag2tm1Fwa
\Rnaseh2atm1Crh/\Rnaseh2atm1Crh
involves: 129S/SvEv 		perinatal lethality, complete penetrance J:232933
\Rag2tm1Fwa/\Rag2tm1Fwa
\Rr299391tm1.1Fwa/\Rr299391tm1.1Fwa
involves: 129P2/OlaHsd * 129S/SvEv 		abnormal T cell receptor delta chain V(D)J recombination J:149413
\Rag2tm1Fwa/\Rag2tm1Fwa
\Sos1tm1.1Les/\Sos1tm1.1Les
\Tg(Lck-cre)1Cwi/0
involves: 129S/SvEv * C57BL/6 		abnormal T cell differentiation J:174536
decreased T cell proliferation J:174536
\Rag2tm1Fwa/\Rag2tm1Fwa
\Stat1tm1Rds/\Stat1tm1Rds
involves: 129S/SvEv * 129S6/SvEvTac 		increased gastrointestinal tumor incidence J:216040
increased mammary adenocarcinoma incidence J:216040
\Rag2tm1Fwa/\Rag2tm1Fwa
\Tbatatm1Faf/\Tbatatm1Faf
involves: 129P2/OlaHsd * 129S/SvEv * C57BL/6 		abnormal bone marrow cell physiology J:166065
abnormal T cell differentiation J:166065
increased thymocyte number J:166065
\Rag2tm1Fwa/\Rag2tm1Fwa
\Tbx21tm1Glm/\Tbx21tm1Glm
involves: 129S/SvEv * 129S6/SvEvTac 		abnormal digestive system physiology J:141481
abnormal intestinal epithelium morphology J:141481
abnormal large intestine crypts of Lieberkuhn morphology J:141481
colitis J:141481
normal digestive/alimentary phenotype J:141481
increased tumor necrosis factor secretion J:141481
large intestinal inflammation J:141481
rectal prolapse J:141481
\Rag2tm1Fwa/\Rag2tm1Fwa
\TcraLn3Jae/\Tcra+
\TcrbLn3Jae/\Tcrb+
involves: 129S/SvEv * 129S4/SvJae * C57BL/6 		abnormal double-negative T cell morphology J:143006
absent gamma-delta T cells J:143006
decreased CD4-positive, alpha-beta T cell number J:143006
increased CD8-positive, alpha-beta T cell number J:143006
\Rag2tm1Fwa/\Rag2tm1Fwa
\TcrbLn3Jae/\Tcrb+
involves: 129S/SvEv * 129S4/SvJae * C57BL/6 		abnormal double-negative T cell morphology J:143006
absent gamma-delta T cells J:143006
decreased CD4-positive, alpha-beta T cell number J:143006
increased double-positive T cell number J:143006
\Rag2tm1Fwa/\Rag2tm1Fwa
\Tg(Cd4-NPM/ALK)N1Ingh/0
involves: 129S/SvEv * C57BL/6 * Swiss Webster 		increased DN3 thymocyte number J:235890
increased T cell derived lymphoma incidence J:235890
increased thymus tumor incidence J:235890
\Rag2tm1Fwa/\Rag2tm1Fwa
\Tg(Cd4-NPM/ALK)N1Ingh/0
\Tg(TcraTcrb)1100Mjb/0
involves: 129S/SvEv * C57BL/6 * Swiss Webster 		increased gastrointestinal stromal tumor incidence J:235890
increased hepatocellular carcinoma incidence J:235890
increased sarcoma incidence J:235890
\Rag2tm1Fwa/\Rag2tm1Fwa
\Tg(DO11.10)10Dlo/0
involves: 129S/SvEv * BALB/c * C3H * C57BL/6 		normal immune system phenotype J:110446
\Rag2tm1Fwa/\Rag2tm1Fwa
\Tg(EmuSR-tTa)83Bop/0
\Tg(tetO-Nfatct1*)1Grc/0
involves: 129S/SvEv * C57BL/6J * CBA/J * FVB/N 		abnormal double-positive T cell morphology J:141917
\Rag2tm1Fwa/\Rag2tm1Fwa
\Tg(Igh-Pim1)1Brn/0
involves: 129S/SvEv * C57BL/6LiA * CBA 		decreased thymocyte number J:114561
\Rag2tm1Fwa/\Rag2tm1Fwa
\Tg(KRT14-Il1f6)1Hblu/?
involves: 129S/SvEv * C57BL/6 * DBA/2 		abnormal skin morphology J:126327
\Rag2tm1Fwa/\Rag2tm1Fwa
\Tg(Lck-Akt1*)M-1Pnt/0
involves: 129S/SvEv * C3H/He * C57BL/6 		absent CD4-positive, alpha-beta T cells J:135903
absent CD8-positive, alpha-beta T cells J:135903
increased double-positive T cell number J:135903
\Rag2tm1Fwa/\Rag2tm1Fwa
\Tg(LPV-TAg1135)11Tvd/0
involves: 129S/SvEv * C57BL/6 * DBA/2 		increased T cell derived lymphoma incidence J:47667
premature death J:47667
\Rag2tm1Fwa/\Rag2tm1Fwa
\Tg(Tcra5CC7,Tcrb5CC7)IWep/?
\Themis5AT161/\Themis5AT161
involves: 129S/SvEv * C57BL/6 		arrested T cell differentiation J:151076
increased double-positive T cell number J:151076
\Rag2tm1Fwa/\Rag2tm1Fwa
\Tg(Tcra51-11.5,Tcrb51-11.5)AR206Ayr/0
involves: 129S/SvEv * C57BL/6 * C57BL/6NTac * DBA/2 		abnormal CD4-positive T cell differentiation J:125548
abnormal positive T cell selection J:125548
decreased CD4-positive, alpha-beta T cell number J:125548
increased double-positive T cell number J:125548
thymus hyperplasia J:125548
\Rag2tm1Fwa/\Rag2tm1Fwa
\Tg(TcraCN.B1,TcrbCN.B1)SM1Jen/0
involves: 129S/SvEv * C57BL/6 		increased susceptibility to bacterial infection induced morbidity/mortality J:162539
\Rag2tm1Fwa/\Rag2tm1Fwa
\Tg(TcraH-Y,TcrbH-Y)71Vbo/?
involves: 129S/SvEv * C57BL/6J * DBA/2J 		abnormal CD8-positive, alpha beta T cell morphology J:125259
abnormal CD8-positive, alpha-beta T cell physiology J:125259
abnormal cytotoxic T cell physiology J:66565
\Rag2tm1Fwa/\Rag2tm1Fwa
\Tg(TcraH-Y,TcrbH-Y)71Vbo/?
\Themis5AT161/\Themis5AT161
involves: 129S/SvEv * C57BL/6 * DBA/2 		decreased single-positive T cell number J:151076
\Rag2tm1Fwa/\Rag2tm1Fwa
\Tg(TcraTcrbNY8.3)1Pesa/0
NOD.Cg-Rag2tm1Fwa Tg(TcraTcrbNY8.3)1Pesa 		increased circulating glucose level J:94192
\Rag2tm1Fwa/\Rag2tm1Fwa
\Tg(TcrHEL3A9)1Mmd/0
involves: 129S/SvEv * C57BL/6 		abnormal CD4-positive, alpha beta T cell morphology J:78309
abnormal double-positive T cell morphology J:78309
abnormal T cell activation J:78309
abnormal T cell proliferation J:78309
abnormal thymus cell ratio J:78309
decreased CD4-positive, alpha-beta T cell number J:78309
\Rag2tm1Fwa/\Rag2tm1Fwa
\Tg(TcrHEL3A9)1Mmd/0
\Tg(TLK2mHEL)2Ccg/0
involves: 129S/SvEv * C57BL/6 		abnormal CD4-positive, alpha beta T cell morphology J:78309
abnormal CD4-positive, alpha-beta T cell physiology J:78309
abnormal T cell activation J:78309
abnormal T cell proliferation J:78309
decreased CD4-positive, alpha-beta T cell number J:78309
decreased double-positive T cell number J:78309
thyroid gland inflammation J:78309
\Rag2tm1Fwa/\Rag2tm1Fwa
\Trp53tm1Tyj/\Trp53tm1Tyj
involves: 129S/SvEv * 129S2/SvPas * C57BL/6J 		increased T cell derived lymphoma incidence J:47667
premature death J:47667
\Rag2tm1Fwa/\Rag2tm1Fwa
\Unc93b1tm1.1Kmiy/\Unc93b1tm1.1Kmiy
involves: 129P2/OlaHsd * 129S/SvEv * C57BL/6 		normal hematopoietic system phenotype J:174308
normal mortality/aging J:174308
\Rag2tm1Fwa/\Rag2tm1Fwa
\Wdr1rede/\Wdr1rede
involves: 129S/SvEv * C57BL/6 		abnormal immune system physiology J:134092
thrombocytopenia J:134092
\Rag2tm2.1Desi/\Rag2tm2.1Desi
\Trp53tm1Tyj/\Trp53tm1Tyj
involves: 129S2/SvPas * 129X1/SvJ * C57BL/6 		increased T cell derived lymphoma incidence J:168974
\Rr148tm1.1Fwa/\Rr148tm1.1Fwa
\Rag2tm1Fwa/\Rag2tm1Fwa
involves: 129S/SvEv * 129S6/SvEvTac 		abnormal B cell differentiation J:101400
\Rr148tm1Fwa/\Rr148tm1Fwa
\Rag2tm1Fwa/\Rag2tm1Fwa
involves: 129S/SvEv * 129S6/SvEvTac 		abnormal B cell differentiation J:101400
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03/25/2025
MGI 6.24 		The Jackson Laboratory