About   Help   FAQ
Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Emx1
empty spiracles homeobox 1
MGI:95387
260 phenotypes from multigenic genotypes
Export: Excel File
Allelic Composition
Genetic Background
Annotated Term Reference
Adcy1tm1Ito/Adcy1tm1.1Ito
Emx1tm1(cre)Ito/Emx1+
B6.129P2-Emx1tm1(cre)Ito Adcy1tm1Ito Adcy1tm1.1Ito
abnormal barrel cortex morphology J:137123
decreased miniature excitatory postsynaptic current amplitude J:137123
normal nervous system phenotype J:137123
reduced long-term potentiation J:137123
Adcy3tm2.1Drs/Adcy3tm2.1Drs
Emx1tm1(cre)Krj/Emx1+
involves: 129S2/SvPas * 129X1/SvJ
abnormal depression-related behavior J:281839
abnormal long-term spatial reference memory J:281839
abnormal object recognition memory J:281839
abnormal response to new environment J:281839
behavioral despair J:281839
hypoactivity J:281839
impaired spatial learning J:281839
Afdntm1c(EUCOMM)Hmgu/Afdntm1c(EUCOMM)Hmgu
Emx1tm1(cre)Krj/Emx1+
involves: 129S2/SvPas * C57BL/6J * C57BL/6N
abnormal cell cycle J:215584
abnormal cerebral cortex morphology J:215584
abnormal cortical ventricular zone morphology J:215584
abnormal embryonic neuroepithelium morphology J:215584
abnormal hippocampus morphology J:215584
abnormal neocortex morphology J:215584
abnormal nervous system tract morphology J:215584
abnormal radial glial cell morphology J:215584
abnormal stratification in cerebral cortex J:215584
abnormal telencephalon development J:215584
ectopic neuron J:215584
increased brain size J:215584
increased neocortex size J:215584
increased neuronal precursor cell number J:215584
increased radial glial cell number J:215584
thin cortical plate J:215584
Arhgef9tm1Betz/Y
Emx1tm1(cre)Yql/Emx1+
involves: 129P2/OlaHsd * 129S2/SvPas * C57BL/6
abnormal neuron morphology J:141850
Atrtm2Bal/Atrtm2Bal
Emx1tm1(cre)Krj/Emx1+
involves: 129S2/SvPas * C57BL/6J
abnormal cerebral cortex morphology J:181920
abnormal corpus callosum morphology J:181920
abnormal stratification in cerebral cortex J:181920
hippocampus hypoplasia J:181920
Atxn1tm2Hzo/Atxn1tm2Hzo
Atxn1ltm2Hzo/Atxn1ltm2Hzo
Emx1tm1(cre)Krj/Emx1+
involves: 129S2/SvPas * 129S7/SvEvBrd
decreased anxiety-related response J:240674
decreased cerebral cortex cell number J:240674
decreased dentate gyrus size J:240674
impaired contextual conditioning behavior J:240674
increased locomotor activity J:240674
thin cerebral cortex J:240674
Bdnftm1Krj/Bdnf+
Emx1tm1(cre)Krj/Emx1+
involves: 129S2/SvPas * C57BL/6J
normal growth/size/body region phenotype J:84683
Bdnftm1Krj/Bdnftm1Lfr
Emx1tm1(cre)Krj/Emx1+
involves: 129S2/SvPas * C57BL/6J
abnormal cerebral cortex morphology J:96903
abnormal hippocampus morphology J:96903
abnormal medium spiny neuron morphology J:96903
abnormal nest building behavior J:84683
abnormal visual cortex morphology J:84683
decreased body weight J:84683
decreased striatum size J:96903
delayed eyelid opening J:84683
increased aggression J:84683
limb grasping J:96903
obese J:84683
premature death J:84683
reduced fertility J:84683
thin cerebral cortex J:84683
Bhlhe22tm2.1Meg/Bhlhe22tm2.1Meg
Emx1tm1(cre)Krj/Emx1+
involves: 129/Sv * 129S2/SvPas
normal behavior/neurological phenotype J:158273
normal integument phenotype J:158273
Bhlhe22tm2.1Meg/Bhlhe22tm2.1Meg
Emx1tm1(cre)Krj/Emx1+
involves: 129S2/SvPas * 129S6/SvEvTac * C57BL/6J
abnormal anterior corticospinal tract morphology J:182304
absent corpus callosum J:182304
absent hippocampal commissure J:182304
Bicd2tm1Hgrd/Bicd2tm1Hgrd
Emx1tm1(cre)Krj/Emx1+
involves: C57BL/6
abnormal hippocampus layer morphology J:210236
abnormal neuronal migration J:210236
abnormal stratification in cerebral cortex J:210236
normal nervous system phenotype J:210236
Bptftm1.1Cwu/Bptftm1.1Cwu
Emx1tm1(cre)Krj/Emx1+
involves: 129S1/Sv * 129S2/SvPas * C57BL/6
abnormal cerebral cortex morphology J:334252
abnormal head shape J:334252
abnormal neuron specification J:334252
abnormal neuronal precursor proliferation J:334252
abnormal stratification in cerebral cortex J:334252
normal behavior/neurological phenotype J:334252
decreased body weight J:334252
decreased brain weight J:334252
decreased forebrain size J:334252
decreased neuronal precursor cell number J:334252
forebrain hypoplasia J:334252
increased neuron apoptosis J:334252
microgliosis J:334252
normal mortality/aging J:334252
Brpf1tm1c(EUCOMM)Wtsi/Brpf1tm1c(EUCOMM)Wtsi
Emx1tm1(cre)Krj/Emx1+
involves: 129S2/SvPas * C57BL/6J * C57BL/6N
abnormal behavior J:241490
abnormal cell cycle checkpoint function J:224155
abnormal cell physiology J:240552
abnormal corpus callosum morphology J:224155
abnormal dentate gyrus morphology J:224155
abnormal hippocampal mossy fiber morphology J:224155
abnormal hippocampus CA1 region morphology J:224155
abnormal hippocampus development J:224155
abnormal hippocampus morphology J:224155
abnormal hippocampus neuron morphology J:224155
abnormal hippocampus pyramidal cell layer J:224155
abnormal hippocampus region morphology J:224155
abnormal neocortex morphology J:224155, J:241490
abnormal nest building behavior J:241490
abnormal neuronal precursor cell migration J:224155
abnormal neuronal stem cell morphology J:224155
abnormal radial glial cell morphology J:224155
decreased body size J:241490
decreased corpus callosum size J:241490
decreased dentate gyrus size J:224155
decreased food intake J:241490
decreased neocortex size J:241490
decreased neuronal precursor cell number J:224155
decreased neuronal precursor proliferation J:224155, J:241490
decreased radial glial cell number J:224155
increased subiculum size J:224155
limb grasping J:241490
normal nervous system phenotype J:241490
postnatal lethality, incomplete penetrance J:224155, J:241490
prenatal growth retardation J:241490
prenatal lethality, incomplete penetrance J:241490
thin cortical plate J:241490
Btbd9tm1c(EUCOMM)Wtsi/Btbd9tm1c(EUCOMM)Wtsi
Emx1tm1(cre)Yql/Emx1+
involves: 129S2/SvPas * 129S4/SvJaeSor * C57BL/6N
abnormal primary motor cortex morphology J:282582
abnormal primary somatosensory cortex morphology J:282582
abnormal sleep behavior J:282582
hyperactivity J:282582
impaired coordination J:282582
increased thermal nociceptive threshold J:282582
Cadpstm1.1Tfr/Cadpstm1.2Tfr
Emx1tm1(cre)Ito/Emx1+
B6.Cg-Emx1tm1(cre)Ito Cadpstm1.1Tfr Cadpstm1.2Tfr
abnormal dentate gyrus morphology J:204664
abnormal Golgi trans cisterna morphology J:204664
abnormal hippocampus pyramidal cell morphology J:204664
abnormal synaptic bouton morphology J:204664
normal nervous system phenotype J:204664
Camk2atm1.1Yelg/Camk2atm1.1Yelg
Emx1tm1.1(cre)Ito/0
B6J.Cg-Camk2atm1.1Yelg Emx1tm1.1(cre)Ito
impaired contextual conditioning behavior J:216169
impaired spatial learning J:216169
Cdh2tm1Glr/Cdh2tm1Glr
Emx1tm1(cre)Krj/Emx1+
involves: 129S6/SvEvTac * C57BL/6
abnormal cerebral cortex morphology J:215584
abnormal cortical ventricular zone morphology J:215584
abnormal neocortex morphology J:215584
abnormal nervous system tract morphology J:215584
abnormal radial glial cell morphology J:215584
ectopic neuron J:215584
increased neuronal precursor cell number J:215584
thickened cerebral cortex J:215584
Cdyltm1.1Yuw/Cdyltm1.1Yuw
Emx1tm1(cre)Yql/Emx1+
involves: 129S2/SvPas * C57BL/6
abnormal neuronal migration J:251551
normal behavior/neurological phenotype J:251551
increased susceptibility to pharmacologically induced seizures J:251551
Celf4tm1.1Frk/Celf4tm1.1Frk
Emx1tm1(cre)Krj/?
involves: 129 * C57BL/6J
increased susceptibility to induction of seizure by inducing agent J:19671
Celsr1tm1Fati/Celsr1tm1Fati
Emx1tm1(cre)Krj/Emx1+
involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ
whorled hair J:157059
Celsr3tm1Agof/Celsr3tm2Agof
Emx1tm1(cre)Krj/Emx1+
involves: 129P2/OlaHsd * 129S2/SvPas
abnormal anterior commissure morphology J:134879
abnormal brain internal capsule morphology J:134879
abnormal corticospinal tract morphology J:134879
Chn1tm1Ito/Chn1tm1.1Ito
Emx1tm1(cre)Krj/Emx1+
involves: 129S2/SvPas * C57BL/6NSlc
normal behavior/neurological phenotype J:209606
Chrm1tm2.1Stl/Chrm1tm2.1Stl
Emx1tm1.1(cre)Ito/0
involves: 129P2/OlaHsd
abnormal excitatory postsynaptic currents J:156540
abnormal long-term depression J:156540
abnormal miniature excitatory postsynaptic currents J:156540
decreased paired-pulse facilitation J:156540
Cictm1c(KOMP)Wtsi/Cictm1c(KOMP)Wtsi
Emx1tm1(cre)Krj/Emx1+
involves: 129S2/SvPas * C57BL/6 * C57BL/6N
abnormal cerebral cortex morphology J:240674
abnormal pyramidal neuron dendrite morphology J:240674
decreased anxiety-related response J:240674
decreased cerebral cortex cell number J:240674
decreased dentate gyrus size J:240674
decreased neurotransmitter release J:240674
impaired contextual conditioning behavior J:240674
increased locomotor activity J:240674
thin cerebral cortex J:240674
Clcn7tm3.1Tjj/Clcn7tm3.1Tjj
Emx1tm1.1(cre)Ito/Emx1+
involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * BALB/cJ * C57BL/6
abnormal cerebral cortex morphology J:155176
abnormal dentate gyrus morphology J:155176
abnormal hippocampus morphology J:155176
abnormal lysosome physiology J:155176
astrocytosis J:155176
enlarged lateral ventricles J:155176
normal growth/size/body region phenotype J:155176
hippocampal neuron degeneration J:155176
limb grasping J:155176
loss of cortex neurons J:155176
loss of hippocampal neurons J:155176
microgliosis J:155176
normal mortality/aging J:155176
neurodegeneration J:155176
normal skeleton phenotype J:155176
Cmtr1tm1b(EUCOMM)Hmgu/Cmtr1tm1b(EUCOMM)Hmgu
Emx1tm1(cre)Krj/Emx1+
Tg(Thy1-YFP)HJrs/0
involves: 129S2/SvPas * C57BL/6J * C57BL/6N * CBA
abnormal dendrite morphology J:300305
abnormal susceptibility to Riboviria infection J:300305
decreased neocortex size J:300305
Ctnnb1tm2Kem/Ctnnb1tm2Kem
Emx1tm1(cre)Yql/Emx1+
B6.129-Emx1tm1(cre)Yql Ctnnb1tm2Kem
abnormal cerebral cortex morphology J:92923
abnormal hippocampus morphology J:92923
abnormal nursing J:92923
absent corpus callosum J:92923
absent dentate gyrus J:92923
absent hippocampal commissure J:92923
absent hippocampus CA1 region J:92923
absent hippocampus CA2 region J:92923
absent hippocampus CA3 region J:92923
decreased body size J:92923
dilated lateral ventricle J:92923
increased susceptibility to pharmacologically induced seizures J:92923
male infertility J:92923
seizures J:92923
Dact1tm1.1Bnrc/Dact1tm1.2Bnrc
Emx1tm1(cre)Krj/Emx1+
involves: 129S2/SvPas
abnormal dendritic spine morphology J:159217
normal nervous system phenotype J:159217
Eif4a3tm1.1Dlsi/Eif4a3+
Emx1tm1(cre)Krj/Emx1+
involves: 129S2/SvPas * C57BL/6J
abnormal neocortex morphology J:235650
abnormal neuronal stem cell morphology J:235650
abnormal telencephalon development J:235650
absent telencephalon J:235650
decreased brain size J:235650
decreased forebrain size J:235650
decreased neocortex size J:235650
microcephaly J:235650
Emx1tm1(cre)Ito/Emx1+
Grin1tm1Stl/Grin1tm2Stl
involves: 129P2/OlaHsd * 129S2/SvPas * 129S4/SvJae * C57BL/6
abnormal postnatal growth J:64064
abnormal primary somatosensory cortex morphology J:80900
abnormal somatosensory cortex morphology J:64064
absent barrels in primary somatosensory cortex J:64064, J:80900
decreased body weight J:64064
reduced NMDA receptor mediated synaptic activity in barrel cortex J:64064
Emx1tm1(cre)Ito/Emx1+
Hes1tm1Fgu/Hes1tm1Hojo
Hes5tm1Fgu/Hes5tm1Fgu
involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ
abnormal neurohypophysis morphology J:121843
abnormal pituitary diverticulum morphology J:121843
abnormal pituitary gland development J:121843
abnormal pituitary gland morphology J:121843
abnormal pituitary infundibular stalk morphology J:121843
absent pituitary intermediate lobe J:121843
increased somatotroph cell number J:121843
pituitary gland hypoplasia J:121843
Emx1tm1(cre)Ito/Emx1+
Olig2tm1Qrlu/Olig2tm1Qrlu
involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6
abnormal myelination J:105071
Emx1tm1(cre)Ito/Emx1+
Htr2atm1Grch/Htr2atm2Grch
129S6.Cg-Htr2atm1Grch Htr2atm2Grch Emx1tm1(cre)Ito
normal behavior/neurological phenotype J:110958
Emx1tm1(cre)Ito/Emx1+
Rgs9tm1.1(cre)Yql/Rgs9+
Tg(HTT*97Q)IXwy/0
involves: 129P2/OlaHsd * FVB
normal behavior/neurological phenotype J:208675
normal nervous system phenotype J:208675
Emx1tm1(cre)Ito/Emx1+
Tg(HTT*97Q)IXwy/0
involves: 129P2/OlaHsd * FVB
normal behavior/neurological phenotype J:208675
decreased locomotor activity J:208675
impaired coordination J:208675
normal nervous system phenotype J:208675
Emx1tm1(cre)Ito/Emx1+
Hes1tm1Kag/Hes1tm1Kag
involves: 129P2/OlaHsd * C57BL/6 * CBA
normal nervous system phenotype J:139170
Emx1tm1(cre)Ito/Emx1+
Hes1tm1Kag/Hes1tm1Kag
Hes3tm1Kag/Hes3tm1Kag
Hes5tm1Fgu/Hes5tm1Fgu
involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA
abnormal brain morphology J:139170
abnormal embryonic neuroepithelium morphology J:139170
abnormal neuron differentiation J:139170
absent choroid plexus J:139170
increased Cajal-Retzius cell number J:139170
Emx1tm1(cre)Ito/Emx1+
Rac1tm1Atai/Rac1tm1Jms
involves: 129P2/OlaHsd * 129S/SvEv * C57BL/6 * ICR
abnormal barrel cortex morphology J:140575
abnormal brain commissure morphology J:140575
abnormal corpus callosum morphology J:140575
abnormal dentate gyrus morphology J:140575
abnormal hippocampus pyramidal cell layer J:140575
abnormal telencephalon morphology J:140575
decreased anterior commissure size J:140575
decreased hippocampal commissure size J:140575
decreased survivor rate J:140575
postnatal lethality, incomplete penetrance J:140575
small hippocampus J:140575
Emx1tm1(cre)Ito/Emx1+
Tg(CAG-Mtor*)#Atai/0
involves: 129P2/OlaHsd * C57BL/6 * DBA/2 * ICR
abnormal cerebral cortex morphology J:211789
decreased neuronal precursor cell number J:211789
increased neuron apoptosis J:211789
small hippocampus J:211789
Emx1tm1(cre)Ito/?
Gt(ROSA)26Sortm1(HD*103Q)Xwy/?
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL
normal nervous system phenotype J:99759
Emx1tm1(cre)Krj/Emx1+
Numbtm1Ynj/Numbtm1Ynj
involves: 129S2/SvPas * 129X1/SvJ * CD-1
no abnormal phenotype detected J:87149
Emx1tm1(cre)Krj/Emx1+
Numbtm1Ynj/Numbtm1Ynj
Numbltm1Wmz/Numbltm1Wmz
involves: 129S2/SvPas * 129X1/SvJ * CD-1
abnormal brain ventricle morphology J:87149
abnormal cerebral cortex morphology J:87149
abnormal cortical marginal zone morphology J:87149
abnormal embryonic neuroepithelium morphology J:87149
abnormal forebrain morphology J:87149
abnormal hearing physiology J:87149
abnormal hippocampus morphology J:87149
abnormal lateral ventricle morphology J:87149
abnormal neuron differentiation J:87149
abnormal neuron specification J:87149
absent corpus callosum J:87149
circling J:87149
decreased body size J:87149
ectopic cortical neuron J:87149
enlarged brain ventricles J:87149
female infertility J:87149
increased neuron apoptosis J:87149
male infertility J:87149
postnatal lethality, incomplete penetrance J:87149
small thalamus J:87149
social withdrawal J:87149
sporadic seizures J:87149
stereotypic behavior J:87149
Emx1tm1(cre)Krj/Emx1+
Wnt3atm2Eag/Wnt3a+
involves: 129S2/SvPas
abnormal cerebral cortex morphology J:104373
abnormal suckling behavior J:104373
absent Cajal-Retzius cell J:104373
absent choroid plexus J:104373
postnatal lethality J:104373
short mandible J:104373
Emx1tm1(cre)Krj/Emx1+
Mycbp2tm1Adia/Mycbp2tm1Adia
involves: 129S2/SvPas * C57BL/6
abnormal axon guidance J:125702
abnormal corpus callosum morphology J:125702
abnormal hippocampus morphology J:125702
decreased corpus callosum size J:125702
enlarged lateral ventricles J:125702
Emx1tm1(cre)Krj/Emx1+
Ptpn11tm6Bgn/Ptpn11+
B6.129S-Ptpn11tm6Bgn Emx1tm1(cre)Krj
abnormal hippocampus neuron morphology J:242312
abnormal spatial learning J:242312
decreased exploration in new environment J:242312
impaired cued conditioning behavior J:242312
Emx1tm1(cre)Krj/Emx1+
Lhx2tm1.1Ddmo/Lhx2tm1.1Ddmo
involves: 129S2/SvPas * C57BL/6 * SJL
abnormal neocortex morphology J:154611
abnormal olfactory bulb morphology J:154611
abnormal olfactory cortex morphology J:154611
abnormal telencephalon morphology J:154611
telencephalon hypoplasia J:154611
Emx1tm1(cre)Krj/Emx1+
Lhx2tm1.1Ddmo/Lhx2tm1.2Ddmo
involves: 129S2/SvPas * C57BL/6 * SJL
abnormal neocortex morphology J:154611
abnormal olfactory bulb morphology J:154611
abnormal olfactory cortex morphology J:154611
abnormal telencephalon morphology J:154611
telencephalon hypoplasia J:154611
Emx1tm1(cre)Krj/Emx1+
Gsx2tm2.1Kc/Gsx2tm2.1Kc
involves: 129S6/SvEvTac * C57BL/6 * SJL
abnormal lateral ganglionic eminence morphology J:154936
abnormal neuron differentiation J:154936
abnormal olfactory bulb morphology J:154936
Emx1tm1(cre)Krj/Emx1+
Gsx2tm2.1Kc/Gsx2tm2.1Kc
Tg(CAG-cat,-EGFP)1Rbns/0
involves: 129S6/SvEvTac * C57BL/6 * C57BL/6J * SJL
abnormal olfactory bulb development J:154936
Emx1tm1(cre)Krj/Emx1+
Esco2tm1.1Ge/Esco2tm1.1Ge
involves: 129S2/SvPas * C57BL/6 * SJL
abnormal embryonic neuroepithelium morphology J:180371
abnormal hippocampus development J:180371
abnormal neocortex morphology J:180371
abnormal neuronal precursor proliferation J:180371
absent hippocampus J:180371
increased neuron apoptosis J:180371
microcephaly J:180371
Emx1tm1(cre)Krj/Emx1+
Topbp1tm1Pmc/Topbp1tm1Pmc
involves: 129S2/SvPas * C57BL/6J
abnormal cerebral cortex morphology J:181920
Emx1tm1(cre)Krj/Emx1+
Tg(CMV-GFP,-Smarcc2,-lacZ)#Stoy/0
involves: 129S2/SvPas
abnormal DNA methylation J:197141
abnormal neocortex morphology J:197141
abnormal neuron differentiation J:197141
abnormal neuron number J:197141
abnormal neuronal precursor cell number J:197141
thin cerebral cortex J:197141
Emx1tm1(cre)Krj/Emx1+
Magohtm1c(KOMP)Dlsi/Magoh+
involves: 129S2/SvPas * C57BL/6J
microcephaly J:235650
Emx1tm1(cre)Krj/Emx1+
Rbm8atm1Dlsi/Rbm8a+
involves: 129S2/SvPas * C57BL/6J
abnormal cerebral cortex morphology J:235650
decreased neuron number J:235650
microcephaly J:235650
Emx1tm1(cre)Krj/Emx1+
Rbm8atm1Dlsi/Rbm8a+
involves: C57BL/6J
abnormal cerebral cortex morphology J:221648
abnormal radial glial cell apoptosis J:221648
abnormal radial glial cell morphology J:221648
abnormal stratification in cerebral cortex J:221648
abnormal telencephalon development J:221648
decreased brain size J:221648
decreased neocortex size J:221648
decreased neuronal precursor cell number J:221648
decreased radial glial cell number J:221648
ectopic cortical neuron J:221648
impaired neuron differentiation J:221648
increased forebrain apoptosis J:221648
increased neuron apoptosis J:221648
increased neuron number J:221648
increased neuronal precursor proliferation J:221648
microcephaly J:221648
premature neuronal precursor differentiation J:221648
small brain ventricles J:221648
thin cerebral cortex J:221648
Emx1tm1(cre)Krj/Emx1+
Rcor2tm1c(EUCOMM)Wtsi/Rcor2tm1c(EUCOMM)Wtsi
involves: 129S2/SvPas * C57BL/6N
decreased brain size J:235702
thin cerebral cortex J:235702
Emx1tm1(cre)Krj/?
Kcnq2tm1.1Avtz/Kcnq2tm1.1Avtz
involves: 129S2/SvPas * C57BL/6
abnormal action potential J:208109
abnormal afterhyperpolarization J:208109
abnormal brain wave pattern J:208109
abnormal hippocampus morphology J:208109
abnormal nervous system electrophysiology J:208109
postnatal lethality, incomplete penetrance J:208109
premature death J:208109
tonic-clonic seizures J:208109
Emx1tm1(cre)Krj/?
Kcnq3tm1.1Avtz/Kcnq3tm1.1Avtz
involves: 129S2/SvPas * C57BL/6
abnormal hippocampus morphology J:208109
abnormal nervous system electrophysiology J:208109
Emx1tm1(cre)Krj/?
Rai1tm2.1Luo/Rai1tm2.1Luo
either: (involves: 129S1/Sv * 129S2/SvPas * C57BL/6) or (involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ * C57BL/6)
no abnormal phenotype detected J:237687
Emx1tm1(cre)Yql/Emx1+
Lhx2tm1Monu/Lhx2tm1Monu
involves: 129P2/OlaHsd * 129S2/SvPas
abnormal cerebral cortex morphology J:130167
Emx1tm1(cre)Yql/Emx1+
Tor1atm2Yql/Tor1atm2Yql
involves: 129S2/SvPas * 129S4/SvJae * C57BL/6
abnormal gait J:130483
abnormal motor coordination/balance J:130483
circling J:130483
hyperactivity J:130483
increased stereotypic behavior J:130483
normal nervous system phenotype J:130483
Emx1tm1.1(cre)Ito/Emx1+
Tg(Gfap-GFAP*R239H)60TMIke/0
involves: 129P2/OlaHsd * C57BL/6J
increased susceptibility to pharmacologically induced seizures J:139349
Emx1tm1.1(cre)Ito/Emx1+
Scn1atm2.1Kzy/Scn1atm2.1Kzy
involves: 129P2/OlaHsd * C57BL/6
abnormal neocortex morphology J:202863
normal behavior/neurological phenotype J:202863
Emx1tm1.1(cre)Ito/Emx1+
Scn1atm2.1Kzy/Scn1atm2.1Kzy
Tg(Slc32a1-cre)65Kzy/0
involves: 129P2/OlaHsd * C57BL/6
convulsive seizures J:202863
premature death J:202863
Emx1tm1Sia/Emx1tm1Sia
Emx2tm1Sia/Emx2+
involves: C57BL/6 * CBA
abnormal cerebral cortex morphology J:163926
abnormal embryonic/fetal subventricular zone morphology J:163926
Emx1tm1Sia/Emx1tm1Sia
Emx2tm1Sia/Emx2tm1Sia
involves: C57BL/6 * CBA
abnormal pallium development J:163926
absent dentate gyrus J:163926
absent hippocampal fimbria J:163926
absent hippocampus J:163926
Emx1tm1Sia/Emx1tm1Sia
Otx1tm1Sia/Otx1tm1Sia
Not Specified
normal nervous system phenotype J:98539
Emx1tm1Sia/Emx1tm1Sia
Otx2tm1Sia/Otx2+
involves: C57BL/6 * CBA
normal nervous system phenotype J:98539
Emx1tm1Sia/Emx1tm1Sia
Rr103tm3.1Sia/Rr103tm3.1Sia
involves: C57BL/6 * CBA
abnormal cerebral cortex morphology J:163926
abnormal pallium development J:163926
absent dentate gyrus J:163926
small hippocampus J:163926
Emx1tm1Sia/Emx1tm1Sia
Rr103tm3Sia/Rr103tm3Sia
involves: C57BL/6 * CBA
abnormal cerebral cortex morphology J:163926
abnormal pallium development J:163926
absent dentate gyrus J:163926
small hippocampus J:163926
Epha4tm1.1Bzh/Epha4tm1.2Bzh
Emx1tm1(cre)Krj/Emx1+
involves: 129S2/SvPas * 129S7/SvEvBrd
abnormal corticospinal tract morphology J:209606
normal behavior/neurological phenotype J:209606
Fezf2tm1.1Nses/Fezf2tm1.1Nses
Emx1tm1(cre)Ito/Emx1+
involves: 129P2/OlaHsd * 129S1/Sv
abnormal corticospinal tract morphology J:186632
Fgf13tm1Xuzh/Y
Emx1tm1(cre)Yql/Emx1+
involves: 129S2/SvPas
abnormal axon morphology J:186253
abnormal cerebral cortex pyramidal cell morphology J:186253
abnormal depression-related behavior J:186253
abnormal object recognition memory J:186253
abnormal spatial learning J:186253
abnormal spatial working memory J:186253
behavioral despair J:186253
hyperactivity J:186253
impaired cued conditioning behavior J:186253
increased anxiety-related response J:186253
Glultm1.1Ncd/Glultm1.1Ncd
Emx1tm1(cre)Krj/Emx1+
B6.Cg-Glultm1.1Ncd Emx1tm1(cre)Krj
abnormal blood vessel physiology J:272643
abnormal brain vasculature morphology J:272643
abnormal locomotor activation J:272643
astrocytosis J:272643
decreased anxiety-related response J:272643
decreased aspartic acid level J:272643
decreased gamma-aminobutyric acid level J:272643
decreased glutamic acid level J:272643
decreased glutamine level J:272643
decreased locomotor activity J:272643
decreased vertical activity J:272643
hippocampus pyramidal cell degeneration J:272643
increased locomotor activity J:272643
neurodegeneration J:272643
premature death J:272643
seizures J:272643
Gm30731tm1.1Dalm/Gm30731tm1.1Dalm
Emx1tm1(cre)Krj/Emx1+
involves: 129S/SvEv * 129S2/SvPas * C57BL/6
abnormal cerebral cortex morphology J:281278
abnormal neocortex morphology J:281278
abnormal neuronal stem cell physiology J:281278
increased neuron number J:281278
Islr2tm1.1Ddg/Islr2tm2.1Ddg
Emx1tm1(cre)Krj/Emx1+
involves: 129S2/SvPas * 129S6/SvEvTac * C57BL/6 * SJL
abnormal brain internal capsule morphology J:210221
abnormal brain morphology J:210221
abnormal telencephalon development J:210221
premature death J:210221
Itgb1tm1Mll/Itgb1tm1Mll
Emx1tm1(cre)Krj/Emx1+
involves: 129S2/SvPas * 129X1/SvJ
abnormal Cajal-Retzius cell morphology J:170581
abnormal radial glial cell morphology J:170581
normal nervous system phenotype J:170581
radial glial endfoot detachment J:170581
Kat6atm1c(EUCOMM)Wtsi/Kat6atm1c(EUCOMM)Wtsi
Emx1tm1(cre)Krj/Emx1+
involves: 129S2/SvPas * C57BL/6J * C57BL/6N * CD-1
no abnormal phenotype detected J:224155
Knl1tm1c(EUCOMM)Hmgu/Knl1tm1c(EUCOMM)Hmgu
Emx1tm1(cre)Krj/Emx1+
involves: 129S2/SvPas * 129S4/SvJaeSor * C57BL/6N
decreased neuron number J:278483
microcephaly J:278483
telencephalon hypoplasia J:278483
Magohtm1c(KOMP)Dlsi/Magoh+
Emx1tm1(cre)Krj/Emx1+
B6.Cg-Magohtm1c(KOMP)Dlsi Emx1tm1(cre)Krj
decreased brain size J:213515
thin cerebral cortex J:213515
Mpp3tm1.1Wij/Mpp3tm1.1Wij
Emx1tm1(cre)Ito/Emx1+
involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6J
abnormal cerebral cortex morphology J:198427
abnormal mitotic spindle morphology J:198427
abnormal neuronal migration J:198427
increased mitotic index J:198427
Nr2f1tm2.1Mist/Nr2f1tm2.1Mist
Emx1tm1(cre)Krj/Emx1+
involves: 129S2/SvPas * C57BL/6J
abnormal barrel cortex morphology J:127387
abnormal cerebral cortex morphology J:127387
abnormal primary somatosensory cortex morphology J:127387
normal nervous system phenotype J:127387
Nrg1tm1Fej/Nrg1tm1Fej
Emx1tm1(cre)Krj/?
involves: 129P2/OlaHsd * 129S2/SvPas
normal nervous system phenotype J:145464
Orc3tm1.1Zhua/Orc3tm1.1Zhua
Emx1tm1(cre)Krj/Emx1+
involves: 129S2/SvPas
abnormal radial glial cell morphology J:170581
decreased neuronal precursor proliferation J:170581
decreased radial glial cell number J:170581
normal nervous system phenotype J:170581
Pals1tm1Caw/Pals1+
Emx1tm1(cre)Krj/Emx1+
involves: 129S2/SvPas
abnormal behavior J:160624
abnormal cerebral cortex morphology J:160624
abnormal neuronal precursor proliferation J:160624
premature neuronal precursor differentiation J:160624
small hippocampus J:160624
Pals1tm1Caw/Pals1tm1Caw
Emx1tm1(cre)Krj/Emx1+
involves: 129S2/SvPas
abnormal brain morphology J:160624
abnormal cerebral cortex morphology J:160624
abnormal gait J:160624
abnormal neuronal precursor proliferation J:160624
abnormal placing response J:160624
abnormal spatial learning J:160624
normal behavior/neurological phenotype J:160624
decreased body weight J:160624
decreased exploration in new environment J:160624
decreased grip strength J:160624
decreased locomotor activity J:160624
disheveled coat J:160624
increased neuron apoptosis J:160624
jerky movement J:160624
jumpy J:160624
loss of cortex neurons J:160624
normal mortality/aging J:160624
premature neuronal precursor differentiation J:160624
normal reproductive system phenotype J:160624
thin cerebral cortex J:160624
Pals1tm1Caw/Pals1tm1Caw
Tsc2tm1.1Mjg/Tsc2tm1.1Mjg
Emx1tm1(cre)Krj/Emx1+
involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ
abnormal cerebral cortex morphology J:160624
Pax6tm2Pgr/Pax6tm2Pgr
Smarcc2tm1.1Stoy/Smarcc2+
Emx1tm1(cre)Krj/Emx1+
involves: 129S1/Sv * 129S2/SvPas * C57BL/6
abnormal neuron number J:197141
normal nervous system phenotype J:197141
Pax6tm2Pgr/Pax6tm2Pgr
Smarcc2tm1.1Stoy/Smarcc2tm1.1Stoy
Emx1tm1(cre)Krj/Emx1+
involves: 129S1/Sv * 129S2/SvPas * C57BL/6
abnormal neocortex morphology J:197141
abnormal neuron number J:197141
abnormal neuronal precursor cell number J:197141
Pdcd10tm1Wami/Pdcd10tm1Wami
Emx1tm1(cre)Krj/Emx1+
involves: 129 * 129S2/SvPas * C57BL/6
abnormal brain vasculature morphology J:170480
astrocytosis J:170480
increased brain size J:170480
increased hemangioma incidence J:170480
normal mortality/aging J:170480
Pik3r4mbe/Pik3r4tm1.1Mpnd
Emx1tm1(cre)Krj/Emx1+
involves: 129S2/SvPas * C3H/HeH * C57BL/6
abnormal hippocampus pyramidal cell layer J:258027
abnormal hippocampus stratum oriens morphology J:258027
ectopic hippocampus pyramidal cells J:258027
Pik3r4tm1.1Mpnd/Pik3r4tm1.1Mpnd
Emx1tm1(cre)Krj/Emx1+
involves: 129S2/SvPas * C57BL/6
abnormal cerebral cortex morphology J:258027
abnormal hippocampus morphology J:258027
thin cerebral cortex J:258027
Pnkptm1.1Pmc/Pnkptm1.1Pmc
Emx1tm1(cre)Krj/Emx1+
involves: 129S1/Sv * 129S2/SvPas * C57BL/6
abnormal cerebellar cortex morphology J:226703
decreased body size J:226703
decreased brain size J:226703
decreased cell proliferation J:226703
increased brain apoptosis J:226703
Pomt2tm1.1Hhu/Pomt2tm1.1Hhu
Emx1tm1(cre)Krj/Emx1+
involves: 129S2/SvPas * 129S4/SvJaeSor * 129S6/SvEvTac * C57BL/6J
abnormal Ammon gyrus morphology J:179356
abnormal basement membrane morphology J:179356
abnormal Cajal-Retzius cell morphology J:179356
abnormal dentate gyrus morphology J:179356
abnormal forebrain morphology J:179356
abnormal hippocampus CA3 region morphology J:179356
abnormal hippocampus layer morphology J:179356
abnormal neocortex morphology J:179356
abnormal radial glial cell morphology J:179356
astrocytosis J:179356
Ppp4r3aem1Qili/Ppp4r3aem1Qili
Emx1tm1(cre)Krj/Emx1+
involves: 129S2/SvPas * C57BL/6J
abnormal miniature excitatory postsynaptic currents J:326388
abnormal sucrose solution preference J:326388
normal behavior/neurological phenotype J:326388
behavioral despair J:326388
decreased dendritic spine density J:326388
decreased neurotransmitter release J:326388
increased anxiety-related response J:326388
increased thigmotaxis J:326388
Ptbp1tm1Nobu/Ptbp1tm2Nobu
Emx1tm1(cre)Ito/Emx1+
involves: 129P2/OlaHsd
abnormal brain ependyma motile cilium morphology J:213479
abnormal telencephalon morphology J:213479
dilated lateral ventricle J:213479
hydrocephaly J:213479
Ptbp2tm1.1Dblk/Ptbp2tm1.1Dblk
Emx1tm1(cre)Ito/Emx1+
involves: 129P2/OlaHsd * 129S2/SvPas
abnormal mitral cell morphology J:207976
abnormal olfactory bulb layer morphology J:207976
absent corpus callosum J:207976
decreased body size J:207976
enlarged lateral ventricles J:207976
neurodegeneration J:207976
neuron degeneration J:207976
postnatal growth retardation J:207976
postnatal lethality, complete penetrance J:207976
slow postnatal weight gain J:207976
small hippocampus J:207976
thin cerebral cortex J:207976
Rem2tm1c(EUCOMM)Hmgu/Rem2tm1c(EUCOMM)Hmgu
Emx1tm1(cre)Krj/Emx1+
involves: 129S2/SvPas * 129S4/SvJaeSor * C57BL/6N
abnormal visual cortex morphology J:263600
Rnu11tm1.1Rank/Rnu11tm1.1Rank
Emx1tm1(cre)Krj/Emx1+
involves: 129S2/SvPas * 129X1/SvJ
abnormal pallium development J:266583
absent hippocampus J:266583
decreased neuron number J:266583
decreased neuronal precursor cell number J:266583
decreased radial glial cell number J:266583
increased cell death J:266583
microcephaly J:266583
Robo4tm1.1Xby/Robo4tm1.1Xby
Emx1tm1(cre)Ito/Emx1+
involves: 129P2/OlaHsd * C57BL/6
normal nervous system phenotype J:202213
Slc12a2tm1.1Jheb/Slc12a2tm1.1Jheb
Emx1tm1(cre)Krj/Emx1+
involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ * C57BL/6
normal behavior/neurological phenotype J:201156
Slc17a6tm1.1Jder/Slc17a6tm1.1Jder
Emx1tm1(cre)Krj/Emx1+
B6.Cg-Emx1tm1(cre)Krj Slc17a6tm1.1Jder
abnormal dendrite morphology J:192240
abnormal dendritic spine morphology J:192240
abnormal glutamate-mediated receptor currents J:192240
abnormal spatial learning J:192240
abnormal spatial reference memory J:192240
decreased body size J:192240
decreased synaptic glutamate release J:192240
increased exploration in new environment J:192240
increased paired-pulse ratio J:192240
reduced long-term depression J:192240
Smarcc2tm1.1Stoy/Smarcc2tm1.1Stoy
Emx1tm1(cre)Krj/Emx1+
involves: 129S1/Sv * 129S2/SvPas * C57BL/6
abnormal DNA methylation J:197141
abnormal neocortex morphology J:197141
abnormal neuron differentiation J:197141
abnormal neuronal precursor cell number J:197141
abnormal neuronal precursor proliferation J:197141
thickened cerebral cortex J:197141
Sp2tm1.1Htg/Sp2tm1.1Htg
Emx1tm1(cre)Krj/Emx1+
involves: 129S2/SvPas
abnormal cortical plate morphology J:194076
abnormal cortical ventricular zone morphology J:194076
abnormal embryonic/fetal subventricular zone morphology J:194076
abnormal neuron differentiation J:194076
prenatal lethality, incomplete penetrance J:194076
Tor1atm1Wtd/Tor1atm3.1Wtd
Emx1tm1(cre)Krj/Emx1+
involves: 129S1/Sv * 129S2/SvPas * 129S6/SvEvTac * C57BL/6J
gliosis J:213785
impaired coordination J:213785
limb grasping J:288753
neurodegeneration J:213785
thin cerebral cortex J:288753
Tor1atm1Wtd/Tor1atm3.1Wtd
Tor1btm1.2Wtd/Tor1btm1.1Wtd
Emx1tm1(cre)Krj/Emx1+
involves: 129S1/Sv * 129S2/SvPas * 129S6/SvEvTac * C57BL/6J
gliosis J:288753
neurodegeneration J:288753
postnatal growth retardation J:288753
premature death J:288753
thin cerebral cortex J:288753
Tor1atm2Wtd/Tor1atm3.1Wtd
Emx1tm1(cre)Krj/Emx1+
involves: 129S1/Sv * 129S2/SvPas * 129S6/SvEvTac * C57BL/6J
normal nervous system phenotype J:288753
Tor1atm2Wtd/Tor1atm3.1Wtd
Tor1btm1.2Wtd/Tor1b+
Emx1tm1(cre)Krj/Emx1+
involves: 129S1/Sv * 129S2/SvPas * 129S6/SvEvTac * C57BL/6J
limb grasping J:288753
thin cerebral cortex J:288753
Tor1atm2Wtd/Tor1atm3.1Wtd
Tor1btm1.2Wtd/Tor1btm1.2Wtd
Emx1tm1(cre)Krj/Emx1+
involves: 129S1/Sv * 129S2/SvPas * 129S6/SvEvTac * C57BL/6J
thin cerebral cortex J:288753
Tsc2tm1.1Kcess/Tsc2tm1.1Kcess
Emx1tm1(cre)Krj/Emx1+
involves: 129S/Sv * C57BL/6J
decreased body weight J:195049
environmentally induced seizures J:195049
postnatal growth retardation J:195049
postnatal lethality, complete penetrance J:195049
Zfp335tm1.1Caw/Zfp335+
Emx1tm1(cre)Krj/Emx1+
involves: 129S2/SvPas * 129S6/SvEvTac * C57BL/6
thin cerebral cortex J:193339
Zfp335tm1.1Caw/Zfp335tm1.1Caw
Emx1tm1(cre)Krj/Emx1+
involves: 129S2/SvPas * 129S6/SvEvTac * C57BL/6
decreased brain size J:193339
loss of cortex neurons J:193339

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
04/23/2024
MGI 6.23
The Jackson Laboratory