Prmt9^em1Sqiu
Endonuclease-mediated Allele Detail

Summary

• Symbol: Prmt9^em1Sqiu
• Name: protein arginine methyltransferase 9; endonuclease-mediated mutation 1, Shenfeng Qiu
• MGI ID: MGI:8166513
• Synonyms: Prmt9^flox
• Gene: Prmt9 Location: Chr8:78276026-78307967 bp, + strand Genetic Position: Chr8, 36.61 cM
• Alliance: Prmt9^em1Sqiu page

Mutation origin

• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready)
• Mutation: Insertion
• Exon 5 was flanked by loxP sites via CRISPR/Cas9 technology. (J:360860)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Prmt9 Mutation: 29 strains or lines available

References

• Original: J:360860 Shen L, et al., Loss-of-function mutation in PRMT9 causes abnormal synapse development by dysregulation of RNA alternative splicing. Nat Commun. 2024 Apr 1;15(1):2809
• All: 1 reference(s)