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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Ptpn11
protein tyrosine phosphatase, non-receptor type 11
MGI:99511
306 phenotypes from 22 alleles in 46 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Cd19tm1(cre)Cgn/Cd19+
Ptpn11tm1Ckq/Ptpn11+
involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6J 		increased acute lymphoblastic leukemia incidence J:177285
increased B cell derived lymphoma incidence J:177285
premature death J:177285
Egr2tm2(cre)Pch/Egr2+
Ptpn11tm1.1Wbm/Ptpn11tm1.1Wbm
involves: 129P2/OlaHsd * 129S2/SvPas * C57BL/6 * SJL 		abnormal myelination J:153219, J:207470
decreased motor neuron number J:153219
decreased nerve conduction velocity J:153219
Emx1tm1(cre)Krj/Emx1+
Ptpn11tm6Bgn/Ptpn11+
B6.129S-Ptpn11tm6Bgn Emx1tm1(cre)Krj 		abnormal hippocampus neuron morphology J:242312
abnormal spatial learning J:242312
decreased exploration in new environment J:242312
impaired cued conditioning behavior J:242312
Hprt1tm1(CAG-cre)Mnn/Hprt1+
Ptpn11tm1Ckq/Ptpn11+
involves: 129S1/Sv * 129S6/SvEvTac * C57BL/6J 		abnormal craniofacial development J:177285
abnormal heart tube morphology J:177285
embryonic growth retardation J:177285
embryonic lethality during organogenesis, complete penetrance J:177285
Meox2tm1(cre)Sor/Meox2+
Ptpn11tm6Bgn/Ptpn11+
involves: 129S4/SvJaeSor * 129S6/SvEvTac * C57BL/6 		abnormal heart morphology J:147154
atrial septal defect J:147154
double outlet right ventricle J:147154
heart valve hyperplasia J:147154
thin myocardium J:147154
ventricular septal defect J:147154
Ptpn11tm1.1Ics/Ptpn11+
involves: 129S2/SvPas * C57BL/6 * FVB/N 		abnormal carbohydrate metabolism J:216593
abnormal cranium size J:216593
abnormal epididymal fat pad morphology J:216593
abnormal fat cell differentiation J:216593
abnormal heart septum morphology J:216593
abnormal lipid level J:216593
cardiac hypertrophy J:216593
decreased brown adipose tissue amount J:216593
decreased cardiac muscle contractility J:216593
decreased cardiac stroke volume J:216593
decreased circulating adiponectin level J:216593
decreased circulating alanine transaminase level J:216593
decreased circulating glucose level J:216593
decreased circulating insulin level J:216593
decreased circulating leptin level J:216593
decreased cranium length J:216593
decreased heart left ventricle posterior wall thickness J:216593
decreased heart rate J:216593
decreased liver triglyceride level J:216593
decreased skeletal muscle triglyceride level J:216593
decreased subcutaneous adipose tissue amount J:216593
decreased susceptibility to diet-induced obesity J:216593
decreased systemic arterial blood pressure J:216593
decreased total body fat amount J:216593
decreased white fat cell number J:216593
dilated cardiomyopathy J:216593
dilated heart left ventricle J:216593
enhanced lipolysis J:216593
enlarged heart J:216593
enlarged spleen J:216593
heart left ventricle hypertrophy J:216593
improved glucose tolerance J:216593
increased adipocyte glucose uptake J:216593
increased energy expenditure J:216593
increased fat cell size J:216593
increased glycerol level J:216593
increased insulin sensitivity J:216593
increased lean body mass J:216593
ocular hypertelorism J:216593
postnatal growth retardation J:216593
slow postnatal weight gain J:216593
Ptpn11tm1.1Rbns/Ptpn11tm1.1Rbns
B6.Cg-Ptpn11tm1.1Rbns 		no abnormal phenotype detected J:150835
Ptpn11tm1.1Rbns/Ptpn11tm1.1Rbns
H2az2Tg(Wnt1-cre)11Rth/H2az2+
B6.Cg-Ptpn11tm1.1Rbns H2az2Tg(Wnt1-cre)11Rth 		abnormal aortic arch and aortic arch branch attachment J:150835
abnormal eye distance/ position J:150835
abnormal mandible morphology J:150835
abnormal nasal bone morphology J:150835
abnormal nasal cartilage morphology J:150835
abnormal nasopharynx morphology J:150835
abnormal tongue morphology J:150835
absent craniofacial bones J:150835
absent mandible J:150835
absent nasal capsule J:150835
common truncal valve J:150835
decreased fetal size J:150835
lethality throughout fetal growth and development, complete penetrance J:150835
microcephaly J:150835
micrognathia J:150835
persistent truncus arteriosus J:150835
small ears J:150835
small snout J:150835
ventricular septal defect J:150835
Ptpn11tm1.1Wbm/Ptpn11tm1.1Wbm
involves: 129P2/OlaHsd * C57BL/6 * SJL 		abnormal Schwann cell physiology J:153219
Ptpn11tm1.1Wbm/Ptpn11tm1.1Wbm
H2az2Tg(Wnt1-cre)11Rth/H2az2+
involves: 129P2/OlaHsd * C57BL/6 * C57BL/6J * SJL * SJL/J 		abnormal axon extension J:153219
abnormal axon fasciculation J:153219
abnormal craniofacial morphology J:153219
abnormal melanocyte morphology J:153219
abnormal sensory neuron innervation pattern J:153219
absent Schwann cell precursors J:153219
decreased enteric neural crest cell number J:153219
decreased Schwann cell number J:153219
decreased Schwann cell precursor number J:153219
decreased sensory neuron number J:153219
embryonic lethality during organogenesis, incomplete penetrance J:153219
Ptpn11tm1.1Wbm/Ptpn11tm1.1Wbm
Tg(Dhh-cre)1Mejr/0
involves: 129P2/OlaHsd * FVB/N 		abnormal Schwann cell physiology J:207470
decreased Schwann cell number J:207470
Ptpn11tm1Bgn/Ptpn11+
129S6.129S4-Ptpn11tm1Bgn 		normal mortality/aging J:147154
Ptpn11tm1Bgn/Ptpn11+
B6.129S4-Ptpn11tm1Bgn 		abnormal heart morphology J:147154
perinatal lethality, incomplete penetrance J:147154
Ptpn11tm1Bgn/Ptpn11+
C.129S4-Ptpn11tm1Bgn 		perinatal lethality, incomplete penetrance J:147154
Ptpn11tm1Bgn/Ptpn11+
involves: 129S4/SvJae * C57BL/6 		abnormal cardiac epithelial to mesenchymal transition J:147154
abnormal common myeloid progenitor cell morphology J:147154
decreased body length J:147154
decreased body weight J:147154
increased inner canthal distance J:147154
perinatal lethality, incomplete penetrance J:147154
Ptpn11tm1Bgn/Ptpn11+
involves: 129S4/SvJae * C57BL/6J 		abnormal heart development J:91609
broad snout J:91609
decreased body length J:91609
decreased body weight J:91609
decreased cardiomyocyte apoptosis J:91609
double outlet right ventricle J:91609
enlarged mitral valve J:91609
enlarged spleen J:91609
flattened snout J:91609
hepatic necrosis J:91609
increased cell proliferation J:91609
increased leukocyte cell number J:91609
increased lymphocyte cell number J:91609
increased neutrophil cell number J:91609
myeloid hyperplasia J:91609
perinatal lethality, incomplete penetrance J:91609
small cranium J:91609
ventricular septal defect J:91609
Ptpn11tm1Bgn/Ptpn11tm1Bgn
involves: 129S4/SvJae * C57BL/6J 		abnormal heart development J:91609
atrial septal defect J:91609
atrioventricular septal defect J:91609
decreased cardiomyocyte apoptosis J:91609
double outlet right ventricle J:91609
embryonic lethality during organogenesis, complete penetrance J:91609
hemorrhage J:91609
hepatic necrosis J:91609
hydrops fetalis J:91609
increased cell proliferation J:91609
pericardial effusion J:91609
small liver J:91609
thin myocardium J:91609
thin myocardium compact layer J:91609
ventricular septal defect J:91609
Ptpn11tm1Ckq/Ptpn11+
involves: 129S6/SvEvTac * C57BL/6J 		no abnormal phenotype detected J:177285
Ptpn11tm1Ckq/Ptpn11+
Lyz2tm1(cre)Ifo/Lyz2+
involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6J 		increased acute promyelocytic leukemia incidence J:177285
myeloid hyperplasia J:177285
premature death J:177285
Ptpn11tm1Ckq/Ptpn11+
Tg(Mx1-cre)1Cgn/0
involves: 129S6/SvEvTac * C57BL/6 * C57BL/6J * CBA 		abnormal bone marrow cell morphology/development J:177285
abnormal hematopoietic stem cell physiology J:177285
anemia J:177285
aneuploidy J:177285
arrested B cell differentiation J:177285
chromosomal instability J:177285
decreased common myeloid progenitor cell number J:177285
decreased hematopoietic stem cell number J:177285
enlarged liver J:177285
enlarged spleen J:177285
extramedullary hematopoiesis J:177285
increased acute lymphoblastic leukemia incidence J:177285
increased acute promyelocytic leukemia incidence J:177285
increased B cell derived lymphoma incidence J:177285
increased hematopoietic stem cell number J:177285
increased leukemia incidence J:177285
increased leukocyte cell number J:177285
increased lymphoblastic lymphoma incidence J:177285
increased neutrophil cell number J:177285
increased spleen weight J:177285
myeloid hyperplasia J:177285
premature death J:177285
Ptpn11tm1Ckq/Ptpn11+
Tg(Lck-cre)1Cwi/0
involves: 129S6/SvEvTac * C57BL/6J 		normal immune system phenotype J:177285
increased acute lymphoblastic leukemia incidence J:177285
increased lymphoblastic lymphoma incidence J:177285
premature death J:177285
Ptpn11tm1Gsf/Ptpn11tm1Gsf
Plekha5Tg(AMH-cre)1Flor/Plekha5+
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL 		abnormal seminiferous tubule epithelium morphology J:250152
abnormal Sertoli cell barrier function J:250152
abnormal Sertoli cell barrier morphology J:250152
abnormal spermatocyte morphology J:250152
abnormal spermatogonia morphology J:250152
arrest of spermatogenesis J:250152
azoospermia J:250152
decreased male germ cell number J:250152
decreased testis weight J:250152
increased Leydig cell number J:250152
increased male germ cell apoptosis J:250152
male infertility J:250152
seminiferous tubule degeneration J:250152
small seminiferous tubules J:250152
Ptpn11tm1Gsf/Ptpn11tm1Gsf
Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA 		abnormal hepatocyte morphology J:172422
abnormal liver morphology J:172422
abnormal liver parenchyma morphology J:172422
focal hepatic necrosis J:172422
hepatic necrosis J:172422
increased acute inflammation J:172422
increased circulating alanine transaminase level J:172422
increased circulating aspartate transaminase level J:172422
increased circulating interleukin-6 level J:172422
increased hepatocyte proliferation J:172422
increased incidence of tumors by chemical induction J:172422
increased liver adenoma incidence J:172422
liver fibrosis J:172422
liver hyperplasia J:172422
liver inflammation J:172422
weight loss J:172422
Ptpn11tm1Gsf/Ptpn11tm1Gsf
Tg(Camk2a-cre)2Szi/0
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA 		abnormal circulating hormone level J:94738
abnormal glucose homeostasis J:94738
abnormal liver morphology J:94738
decreased body temperature J:94738
decreased circulating thyroxine level J:94738
decreased circulating triiodothyronine level J:94738
enlarged liver J:94738
hepatic steatosis J:94738
hyperglycemia J:94738
hypersecretion of corticosterone J:94738
hypoglycemia J:94738
increased body length J:94738
increased brown adipose tissue amount J:94738
increased circulating corticosterone level J:94738
increased circulating growth hormone level J:94738
increased circulating insulin level J:94738
increased circulating leptin level J:94738
increased circulating thyroid-stimulating hormone level J:94738
increased circulating triglyceride level J:94738
increased liver glycogen level J:94738
increased liver triglyceride level J:94738
increased susceptibility to weight gain J:94738
increased white adipose tissue amount J:94738
obese J:94738
reduced female fertility J:94738
Ptpn11tm1Gsf/Ptpn11tm1Gsf
Tg(Ckmm-cre)5Khn/0
involves: 129S1/Sv * 129X1/SvJ * FVB 		abnormal heart echocardiography feature J:144767
abnormal myocardial fiber calcium currents J:144767
congestive heart failure J:144767
decreased cardiac muscle cell glucose uptake J:144767
decreased muscle cell glucose uptake J:144767
decreased ventricle muscle contractility J:144767
dilated cardiomyopathy J:144767
enlarged heart J:144767
impaired glucose tolerance J:144767
increased cardiac muscle triglyceride level J:144767
increased circulating insulin level J:144767
increased circulating triglyceride level J:144767
increased heart ventricle size J:144767
increased myocardial fiber size J:144767
increased skeletal muscle triglyceride level J:144767
insulin resistance J:144767
premature death J:144767
Ptpn11tm1Gsf/Ptpn11tm1Gsf
Tg(Col2a1-cre/ERT2)1Dic/0
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 		abnormal gait J:324822
abnormal spine curvature J:324822
abnormal vertebral column morphology J:324822
abnormal vertebral epiphyseal plate morphology J:324822
ectopic cartilage J:233244
exostosis J:233244
kyphoscoliosis J:324822
kyphosis J:324822
lordosis J:324822
scoliosis J:324822
normal skeleton phenotype J:324822
Ptpn11tm1Gsf/Ptpn11tm1Gsf
Tg(Inha-cre)3Zuk/0
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL 		arrest of spermatogenesis J:250152
male infertility J:250152
seminiferous tubule degeneration J:250152
small testis J:250152
Ptpn11tm1Gsf/Ptpn11tm1Gsf
Tg(Pax6-cre,GFP)1Pgr/0
involves: 129S1/Sv * 129X1/SvJ * FVB 		abnormal lacrimal gland development J:130571
absent lacrimal glands J:130571
Ptpn11tm1Gsf/Ptpn11tm1Gsf
Tg(Six3-cre)69Frty/0
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA/2 		abnormal cone electrophysiology J:174095
abnormal retina inner nuclear layer morphology J:174095
abnormal rod electrophysiology J:174095
decreased a-wave amplitude J:174095
decreased b-wave amplitude J:174095
optic nerve atrophy J:174095
retina degeneration J:174095
retina ganglion cell degeneration J:174095
retina outer nuclear layer degeneration J:174095
thin retina ganglion layer J:174095
thin retina inner nuclear layer J:174095
thin retina inner plexiform layer J:174095
thin retina outer nuclear layer J:174095
Ptpn11tm1Paw/Ptpn11tm1Paw
involves: 129S1/Sv * 129X1/SvJ 		abnormal cell death J:106624
decreased cell proliferation J:106624
polyploidy J:106624
Ptpn11tm1Paw/Ptpn11tm1Paw
involves: 129S1/Sv * 129X1/SvJ * CD-1 		abnormal allantois morphology J:43740
abnormal axial mesoderm morphology J:43740
abnormal embryonic neuroepithelium morphology J:43740
abnormal gastrulation J:43740
abnormal heart development J:43740
abnormal neural tube morphology J:43740
abnormal notochord morphology J:43740
abnormal rostral-caudal axis patterning J:43740
abnormal visceral yolk sac morphology J:43740
abnormal vitelline vascular remodeling J:43740
caudal body truncation J:43740
embryonic growth arrest J:43740
embryonic growth retardation J:43740
embryonic lethality during organogenesis, complete penetrance J:43740
failure of initiation of embryo turning J:43740
incomplete somite formation J:43740
kinked neural tube J:43740
open neural tube J:43740
Ptpn11tm1Rbn/Ptpn11+
involves: 129 * Black Swiss 		no abnormal phenotype detected J:35137
Ptpn11tm1Rbn/Ptpn11tm1Rbn
involves: 129 * Black Swiss 		decreased litter size J:35137
embryonic lethality, complete penetrance J:35137
Ptpn11tm1Yan/Ptpn11tm1Yan
Tg(Ckmm-cre)5Khn/0
involves: 129/Sv * C57BL/6 * FVB 		decreased skeletal muscle fiber number J:114499
decreased skeletal muscle fiber size J:114499
Ptpn11tm2Bgn/Ptpn11tm2Bgn
involves: 129S4/SvJae 		disorganized embryonic tissue J:106624
embryonic lethality between implantation and somite formation, complete penetrance J:106624
inner cell mass degeneration J:106624
Ptpn11tm3Bgn/Ptpn11tm3Bgn
involves: 129X1/SvJ * C57BL/6J 		improved glucose tolerance J:167406
Ptpn11tm3Bgn/Ptpn11tm3Bgn
Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+
involves: 129X1/SvJ * C57BL/6 * C57BL/6J * DBA 		decreased circulating glucose level J:167406
decreased circulating insulin level J:167406
decreased circulating triglyceride level J:167406
improved glucose tolerance J:167406
increased insulin sensitivity J:167406
Ptpn11tm4.2Bgn/Ptpn11+
B6.129S6-Ptpn11tm4.2Bgn 		abnormal interventricular septum morphology J:301775
cardiac fibrosis J:301775
increased heart weight J:301775
thick ventricular wall J:301775
Ptpn11tm4.2Bgn/Ptpn11+
involves: 129S6/SvEvTac * C57BL/6J * FVB/N 		abnormal chest morphology J:172033
abnormal cranium size J:172033
abnormal eye distance/ position J:172033
abnormal facial morphology J:172033
abnormal organ of Corti morphology J:172033
abnormal reproductive system morphology J:172033
cardiac fibrosis J:172033
cardiac hypertrophy J:172033
normal cardiovascular system phenotype J:172033
decreased body size J:172033
decreased ventricle muscle contractility J:172033
depressed nasal bridge J:172033
dilated cardiomyopathy J:172033
enlarged heart J:172033
heart left ventricle hypertrophy J:172033
normal hematopoietic system phenotype J:172033
increased heart weight J:172033
increased myocardial fiber size J:172033
ocular hypertelorism J:172033
pectus carinatum J:172033
pectus excavatum J:172033
premature death J:172033
short femur J:172033
thick interventricular septum J:172033
thick ventricular wall J:172033
Ptpn11tm5Bgn/Ptpn11tm5Bgn
involves: 129S4/SvJae * C57BL/6J 		abnormal blastocyst morphology J:106624
abnormal endoderm development J:106624
abnormal trophectoderm morphology J:106624
decreased trophectoderm cell proliferation J:106624
embryonic lethality at implantation, incomplete penetrance J:106624
impaired embryo implantation J:106624
Ptpn11tm6Bgn/Ptpn11+
Tg(Tek-cre)12Flv/0
involves: 129S6/SvEvTac * C3H * C57BL/6 		double outlet right ventricle J:147154
embryonic lethality J:147154
increased atrioventricular cushion size J:147154
thin myocardium J:147154
ventricular septal defect J:147154
Ptpn11tm6Bgn/Ptpn11+
Tg(EIIa-cre)C5379Lmgd/0
involves: 129S6/SvEvTac * FVB/N 		preweaning lethality, complete penetrance J:148430
Ptpn11tm6Bgn/Ptpn11+
Tg(Mx1-cre)1Cgn/0
involves: 129S6/SvEvTac * C57BL/6 * CBA 		abnormal bone marrow cell number J:148430
abnormal definitive hematopoiesis J:148430
abnormal erythropoiesis J:148430
abnormal leukopoiesis J:148430
abnormal liver sinusoid morphology J:148430
abnormal splenic cell ratio J:148430
anemia J:148430
decreased bone marrow cell number J:148430
decreased common myeloid progenitor cell number J:148430
decreased granulocyte monocyte progenitor cell number J:148430
decreased hematopoietic stem cell number J:148430
enlarged liver J:148430
enlarged spleen J:148430
extramedullary hematopoiesis J:148430
increased granulocyte number J:148430
increased leukocyte cell number J:148430
increased monocyte cell number J:148430
intermingled spleen red and white pulp J:148430
premature death J:148430
Ptpn11tm6Bgn/Ptpn11+
Tg(CAG-cre/Esr1*)5Amc/0
involves: 129S6/SvEvTac * C57BL/6 * CBA 		abnormal definitive hematopoiesis J:148430
abnormal leukopoiesis J:148430
Ptpn11tm6Bgn/Ptpn11+
H2az2Tg(Wnt1-cre)11Rth/H2az2+
involves: 129S6/SvEvTac * C57BL/6 * CBA/J 		normal cardiovascular system phenotype J:147154
decreased cranium height J:147154
increased inner canthal distance J:147154
Ptpn11tm6Bgn/Ptpn11+
Tg(Myh6-cre)2182Mds/0
involves: 129S6/SvEvTac * C57BL/6 * FVB/N 		normal cardiovascular system phenotype J:147154
Ptpn11tm7Bgn/Ptpn11+
involves: 129S4/SvJae * 129S6/SvEvTac * C57BL/6 		abnormal common myeloid progenitor cell morphology J:147154
decreased body length J:147154
decreased body weight J:147154
decreased cranium height J:147154
Ptpn11tm7Bgn/Ptpn11tm7Bgn
involves: 129S4/SvJae * 129S6/SvEvTac * C57BL/6 		abnormal common myeloid progenitor cell morphology J:147154
atrial septal defect J:147154
decreased body length J:147154
decreased body weight J:147154
decreased cranium height J:147154
decreased survivor rate J:147154
double outlet right ventricle J:147154
increased atrioventricular cushion size J:147154
increased inner canthal distance J:147154
thin myocardium J:147154
ventricular septal defect J:147154
Tg(CAG-cat,-Ptpn11)1Rbns/0
Tg(Tek-cre)12Flv/0
involves: C3H * C57BL/6 * FVB/N 		normal cardiovascular system phenotype J:142212
Tg(Myh6-Ptpn11)75Rbns/0
FVB.Cg-Tg(Myh6-Ptpn11)75Rbns 		normal cardiovascular system phenotype J:123963
Tg(Myh6-Ptpn11*Q79R)197Rbns/0
FVB.Cg-Tg(Myh6-Ptpn11*Q79R)197Rbns 		normal cardiovascular system phenotype J:123963
Tg(Myh6-Ptpn11*Q510E)#Krnz/0
FVB/N-Tg(Myh6-Ptpn11*Q510E)#Krnz 		normal cardiovascular system phenotype J:181656
Tg(Myh7-Ptpn11)294Rbns/0
FVB.Cg-Tg(Myh7-Ptpn11)294Rbns 		normal cardiovascular system phenotype J:123963
Tg(Myh7-Ptpn11*Q79R)11Rbns/0
FVB.Cg-Tg(Myh7-Ptpn11*Q79R)11Rbns 		abnormal atrial thrombosis J:123963
abnormal cardiovascular system physiology J:123963
abnormal interventricular groove morphology J:123963
decreased cardiac muscle contractility J:123963
dilated heart atrium J:123963
dilated heart ventricle J:123963
increased heart weight J:123963
increased lung weight J:123963
premature death J:123963
thick ventricular wall J:123963
ventricular cardiomyopathy J:123963
ventricular septal defect J:123963
Tg(Myh7-Ptpn11*Q510E)#Krnz/0
FVB/N-Tg(Myh7-Ptpn11*Q510E)#Krnz 		abnormal heart echocardiography feature J:181656, J:222124
abnormal heart ventricle shape J:181656
abnormal interventricular groove morphology J:181656
abnormal myocardial fiber morphology J:222124
abnormal myocardial fiber physiology J:222124
cardiac hypertrophy J:181656, J:222124
cardiac interstitial fibrosis J:181656
cardiomyopathy J:181656
decreased cardiac muscle contractility J:181656
fetal cardiomyocyte disarray J:181656
increased cardiac muscle contractility J:222124
increased fetal cardiomyocyte size J:181656
increased heart atrium size J:181656
increased heart left atrium size J:181656
increased heart weight J:181656, J:222124
increased myocardial fiber size J:181656, J:222124
myocardial fiber disarray J:181656
thick interventricular septum J:181656
ventricular septal defect J:181656
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04/30/2024
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